Protective effect of green tea polyphenol (-)-epigallocatechin gallate and other antioxidants on lipid peroxidation in gerbil brain homogenates

Phytotherapy Research

Volumn 17, Issue 3, 2003, Pages 206-209

  Lee, Seong Ryong ^a   Im, Ki Jo ^a   Suh, Seong Il ^a   Jung, Jung Gil ^a  

^a Keimyung University   (South Korea)

Author keywords

Antioxidant; Brain homogenate; EGCG; Lipid peroxidation; Lipoic acid; Melatonin; Trolox

Indexed keywords

AMMONIUM SULFATE; ANTIOXIDANT; EPIGALLOCATECHIN GALLATE; FERROUS ION; GREEN TEA EXTRACT; HYDROGEN PEROXIDE; MELATONIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOCTIC ACID; TROLOX C;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; ENZYME SUBSTRATE; FENTON REACTION; GERBIL; IC 50; IN VITRO STUDY; LIPID PEROXIDATION; MALE; NEUROPROTECTION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; TEA;

ANIMALS; ANTIOXIDANTS; BRAIN; CATECHIN; CHROMANS; DOSE-RESPONSE RELATIONSHIP, DRUG; FERROUS COMPOUNDS; FLAVONOIDS; GERBILLINAE; HYDROGEN PEROXIDE; INHIBITORY CONCENTRATION 50; LIPID PEROXIDATION; MALE; MELATONIN; PHENOLS; PHYTOTHERAPY; POLYMERS; QUATERNARY AMMONIUM COMPOUNDS; TEA; THIOBARBITURIC ACID REACTIVE SUBSTANCES; THIOCTIC ACID;

GERBILLINAE;

EID: 0037354510     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1090     Document Type: Article

References (21)

1. Aguirre N, Barrionuevo M, Ramirez MJ et al. 1999. Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity. Neuroreport 10: 3675-3680.
2. Aucamp J, Gaspar A, Hara Y, Apostolides Z. 1997. Inhibition of xanthine oxidase by catechins from tea (Camellia sinensis). Anticancer Res 17: 4381-4386.
3. Barlow-Waldon LR, Reiter RJ, Abe M et al. 1995. Melatonin eliminates brain glutathione peroxidase activity. Neurochem Int 26: 497-502.
4. Biewenga GP, Haenen GR, Bast A. 1997. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol 29: 315-331.
5. Chan MM, Fong D, Ho CT, Huang HI. 1997. Inhibition of inducible nitric oxide synthase gene expression and enzyme activity by epigallocatechin gallate, a natural product from green tea. Biochem Pharmacol 54: 1281-1286.
6. Garcia JJ, Martinez-Ballarin E, Robinson M et al. 2000. Protective effect of β-carbolines and other antioxidants on lipid peroxidation due to hydrogen peroxide in rat brain homogenates. Neurosci Lett 294: 1-4.
7. Guo Q, Zhao B, Li M et al. 1996. Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes. Biochim Biophys Acta 1304: 210-222.
8. Kabuto H, Yokoi I, Ogawa N. 1998. Melatonin inhibits iron-induced epileptic discharges in rats by suppressing peroxidation. Epilepsia 39: 237-243.
9. Lee SR, Suh SI, Kim SP. 2000. Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils. Neurosci Lett 287: 191-194.
10. Limson J, Nyoong T, Daya S. 1998. The interaction of melatonin and its precursors with aluminum, calcium, copper, iron, lead, and zinc: an adsorptive voltammetric study. J Pineal Res 24: 15-21.
11. Manev H, Uz T, Kharlamov A, Joo JY. 1996. Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats. FASEB J 10: 1546-1551.
12. Matsuo N, Yamada K, Shoji K. 1997. Effect of tea polyphenols on histamine release from rat basophilic leukemia (RBL-2H3) cells: the structure-inhibitory activity relationship. Allergy 52: 58-64.
13. Melchiorri D, Reiter RJ, Attia A et al. 1995. Potent protective effect of melatonin on in vivo paraquat induced toxicity. Life Sci 56: 83-88.
14. Muller U, Krieglstein J. 1995. Prolonged pretreatment with alpha-lipoic acid protects cultured neurons against hypoxic, glutamate- or iron-induced injury. J Cereb Blood Flow Metab 15: 624-630.
15. Packer L, Tritschler HJ, Wessel K. 1997. Neuroprotection by the metabolic antioxidant α-lipoic acid. Free Radical Biol Med 22:359-378.
16. Reiter RJ. 1995. Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J 9: 526-533.
17. Reiter RJ. 1996. Functional aspects of the pineal hormone melatonin in combating cell and tissue damage induced by free radicals. Eur J Endocrinol 134: 412-420.
18. Sinet PM, Heikkila RE, Cohen G. 1980. Hydrogen peroxide production by rat brain in vivo. J Neurochem 34: 1421-1426.
19. Suganuma M, Okabe S, Oniyama M et al. 1998. Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue. Carcinogenesis 19: 1771-1776.
20. Tan DX, Chen LD, Poeggeler B et al. 1993. Melatonin: a potent endogenous hydroxyl radical scavenger. Endocrinol J 1: 57-60.
21. Winterbourn CC. 1995. Toxicity of iron and hydrogen peroxide: the Fenton reaction. Toxicol Lett 82-83: 969-974.