Synthesis of 8-thiabicyclo[3.2.1]oct-2-enes and their binding affinity for the dopamine and serotonin transporters

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 24, 2004, Pages 6007-6010

  Meltzer, Peter C ^a   Pham Huu, Duy Phong ^a   Madras, Bertha K ^b  

^a ORGANIX INC   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLOROPHENYL 8 THIABICYCLO[3.2.1]OCT 2 ENE; DOPAMINE TRANSPORTER; OCTANE; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

AMINE TRANSPORT; ARTICLE; BINDING AFFINITY; DRUG BINDING; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50;

ALKENES; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING, COMPETITIVE; CITALOPRAM; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT MODULATORS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR STRUCTURE; NERVE TISSUE PROTEINS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 8844254052     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.09.080     Document Type: Article

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