2-carbomethoxy-3-aryl-8-bicyclo[3.2.1]octanes: Potent non-nitrogen inhibitors of monoamine transporters

Journal of Medicinal Chemistry

Volumn 43, Issue 16, 2000, Pages 2982-2991

  Meltzer, P C ^a   Blundell, P ^a   Yong, Y F ^a   Chen, Z ^a   George, C ^b   Gonzalez, M D ^a   Madras, B K ^c  

^a ORGANIX INC   (United States)

^b NAVAL RESEARCH LABORATORY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; BICYCLO[3.2.1]OCTANE DERIVATIVE; CITALOPRAM; COCAINE DERIVATIVE; DOPAMINE TRANSPORTER; MONOAMINE; TRITIUM;

ARTICLE; CENTRAL NERVOUS SYSTEM; CHEMICAL STRUCTURE; COCAINE DEPENDENCE; DOPAMINERGIC SYSTEM; DRUG ABUSE; LIGAND BINDING; STRUCTURE ACTIVITY RELATION;

ANIMALS; BICYCLO COMPOUNDS; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; LIGANDS; MACACA FASCICULARIS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; PROTEIN BINDING; PUTAMEN; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034632801     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000191g     Document Type: Article

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