Carbonic anhydrase inhibitors - Part 49: Synthesis of substituted ureido and thioureido derivatives of aromatic/heterocyclic sulfonamides with increased affinities for isozyme I

European Journal of Medicinal Chemistry

Volumn 33, Issue 2, 1998, Pages 83-93

  Supuran, Claudiu T ^a   Scozzafava, Andrea ^a   Jurca, Bogdan C ^b   Ilies, Marc A ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF BUCHAREST   (Romania)

Author keywords

1,3 Disubstituted (thio)ureas; 1,5 Disubstituted 2 thiobiurets; Aromatic; Carbonic anhydrase; Heterocyclic sulfonamide; Isocyanate; Isothiocyanate; Isozyme I, II, IV; Isozyme specific inhibitor

Indexed keywords

CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; ISOENZYME; SULFONAMIDE; THIOUREA DERIVATIVE; UREA DERIVATIVE;

ARTICLE; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SPECIFICITY; HUMAN; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

EID: 0032007213     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(98)80033-0     Document Type: Article

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