메뉴 건너뛰기




Volumn 25, Issue 11, 2004, Pages 2115-2123

Anti-angiogenic activity of inositol hexaphosphate (IP6)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; BASIC FIBROBLAST GROWTH FACTOR; CALRETICULIN; MATRIGEL; MESSENGER RNA; PHYTIC ACID; UNCLASSIFIED DRUG; VASCULOTROPIN; VASOSTATIN;

EID: 8844244745     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh232     Document Type: Article
Times cited : (91)

References (72)
  • 3
    • 0025021262 scopus 로고
    • Antioxidant functions of phytic acid
    • Graf,E. and Eaton,J.W. (1990) Antioxidant functions of phytic acid. Free Radical Biol. Med., 8, 61-69.
    • (1990) Free Radical Biol. Med. , vol.8 , pp. 61-69
    • Graf, E.1    Eaton, J.W.2
  • 4
    • 0029036869 scopus 로고
    • Metabolism and biological activities of inositol pentakisphosphates and inositol hexakis-phosphate
    • Sasakawa,N., Sharif,M. and Hanley,M.R. (1995) Metabolism and biological activities of inositol pentakisphosphates and inositol hexakis-phosphate. Biochem. Pharmacol., 50, 137-146.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 137-146
    • Sasakawa, N.1    Sharif, M.2    Hanley, M.R.3
  • 5
    • 0029693744 scopus 로고    scopus 로고
    • Inositol pentakis- and hexakisphosphate metabolism adds versatility to the actions of inositol polyphosphates: Novel effects on ion channels and protein traffic
    • Shears,S.B. (1996) Inositol pentakis- and hexakisphosphate metabolism adds versatility to the actions of inositol polyphosphates: novel effects on ion channels and protein traffic. Sub-Cell. Biochem. 26, 187-226.
    • (1996) Sub-Cell. Biochem. , vol.26 , pp. 187-226
    • Shears, S.B.1
  • 8
    • 0033516604 scopus 로고    scopus 로고
    • A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export
    • York,J.D., Odom,A.R., Murphy,R., Ives,E.B. and Wente,S.R. (1999) A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. Science, 285, 96-100.
    • (1999) Science , vol.285 , pp. 96-100
    • York, J.D.1    Odom, A.R.2    Murphy, R.3    Ives, E.B.4    Wente, S.R.5
  • 9
    • 0034677903 scopus 로고    scopus 로고
    • A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control
    • Odom,A.R., Stahlberg,A., Wente,S.R. and York,J.D. (2000) A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control. Science, 287, 2026-2029.
    • (2000) Science , vol.287 , pp. 2026-2029
    • Odom, A.R.1    Stahlberg, A.2    Wente, S.R.3    York, J.D.4
  • 11
    • 0036392197 scopus 로고    scopus 로고
    • Anti-cancer function of phytic acid
    • Shamsuddin,A.M. (2002) Anti-cancer function of phytic acid. Int. J. Food Sci. Technol., 37, 769-782.
    • (2002) Int. J. Food Sci. Technol. , vol.37 , pp. 769-782
    • Shamsuddin, A.M.1
  • 13
    • 0030499776 scopus 로고    scopus 로고
    • 6: Growth inhibition and differentiation of human mammary cancer cell lines in vitro
    • 6: growth inhibition and differentiation of human mammary cancer cell lines in vitro. Anticancer Res., 16, 3287-3292.
    • (1996) Anticancer Res. , vol.16 , pp. 3287-3292
    • Shamsuddin, A.M.1    Yang, G.-Y.2    Vucenik, I.3
  • 14
    • 0027442548 scopus 로고
    • Growth inhibition and differentiation of HT-29 cells in vitro by inositol hexaphosphate (phytic acid)
    • Sakamoto,K., Venkatraman,G. and Shamsuddin,A.M. (1993) Growth inhibition and differentiation of HT-29 cells in vitro by inositol hexaphosphate (phytic acid). Carcinogenesis, 14, 1815-1819.
    • (1993) Carcinogenesis , vol.14 , pp. 1815-1819
    • Sakamoto, K.1    Venkatraman, G.2    Shamsuddin, A.M.3
  • 15
    • 0027761183 scopus 로고
    • Inhibition of mammary carcinogenesis by inositol hexaphosphate (phytic acid). A pilot study
    • Vucenik,I., Sakamoto,K., Bansal,M. and Shamsuddin,A.M. (1993) Inhibition of mammary carcinogenesis by inositol hexaphosphate (phytic acid). A pilot study. Cancer Lett., 75, 95-102.
    • (1993) Cancer Lett. , vol.75 , pp. 95-102
    • Vucenik, I.1    Sakamoto, K.2    Bansal, M.3    Shamsuddin, A.M.4
  • 16
    • 0029057655 scopus 로고
    • Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer
    • Vucenik,I., Yang,G.-Y. and Shamsuddin,A.M. (1995) Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer. Carcinogenesis, 16, 1055-1058.
    • (1995) Carcinogenesis , vol.16 , pp. 1055-1058
    • Vucenik, I.1    Yang, G.-Y.2    Shamsuddin, A.M.3
  • 17
    • 0030855536 scopus 로고    scopus 로고
    • 6) and high-bran diet in the prevention of DMBA-induced rat mammary carcinogenesis
    • 6) and high-bran diet in the prevention of DMBA-induced rat mammary carcinogenesis. Nutr. Cancer 28, 7-13.
    • (1997) Nutr. Cancer , vol.28 , pp. 7-13
    • Vucenik, I.1    Yang, G.-Y.2    Shamsuddin, A.M.3
  • 19
    • 0024517059 scopus 로고
    • Inositol hexaphosphate inhibits large intestinal cancer in F344 rats 5 months after induction by azoxymethane
    • Shamsuddin,A.M. and Ullah,A. (1989) Inositol hexaphosphate inhibits large intestinal cancer in F344 rats 5 months after induction by azoxymethane. Carcinogenesis, 10, 625-626.
    • (1989) Carcinogenesis , vol.10 , pp. 625-626
    • Shamsuddin, A.M.1    Ullah, A.2
  • 20
    • 0024405693 scopus 로고
    • Inositol and inositol hexaphosphate suppresses cell proliferation and tumor formation in CD-1 mice
    • Shamsuddin,A.M., Ullah,A. and Chakravarthy,A. (1989) Inositol and inositol hexaphosphate suppresses cell proliferation and tumor formation in CD-1 mice. Carcinogenesis, 10, 1461-1463.
    • (1989) Carcinogenesis , vol.10 , pp. 1461-1463
    • Shamsuddin, A.M.1    Ullah, A.2    Chakravarthy, A.3
  • 21
    • 0025612325 scopus 로고
    • Dose-dependent inhibition of large intestinal cancer by inositol hexaphosphate in F344 rats
    • Ullah,A. and Shamsuddin,A.M. (1990) Dose-dependent inhibition of large intestinal cancer by inositol hexaphosphate in F344 rats. Carcinogenesis, 11, 2219-2222.
    • (1990) Carcinogenesis , vol.11 , pp. 2219-2222
    • Ullah, A.1    Shamsuddin, A.M.2
  • 22
    • 0026686410 scopus 로고
    • Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate
    • Pretlow,T.P., O'Riordan,M.A., Somich,G.A., Amini,S.B. and Pretlow,T.G. (1992) Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate. Carcinogenesis, 13, 1509-1512.
    • (1992) Carcinogenesis , vol.13 , pp. 1509-1512
    • Pretlow, T.P.1    O'Riordan, M.A.2    Somich, G.A.3    Amini, S.B.4    Pretlow, T.G.5
  • 23
    • 0031408142 scopus 로고    scopus 로고
    • Interactive suppression of aberrant crypt foci induced by azoxymethane in rat colon by phytic acid and green tea
    • Challa,A., Rao,D.R. and Reddy,B.S. (1997) Interactive suppression of aberrant crypt foci induced by azoxymethane in rat colon by phytic acid and green tea. Carcinogenesis, 18, 2023-2026.
    • (1997) Carcinogenesis , vol.18 , pp. 2023-2026
    • Challa, A.1    Rao, D.R.2    Reddy, B.S.3
  • 24
    • 0026658125 scopus 로고
    • Antitumor activity of phytic acid (inositol hexaphosphate) in murine transplanted and metastatic fibrosarcoma, a pilot study
    • Vucenik,I., Tomazic,V.J., Fabian,D. and Shamsuddin,A.M. (1992) Antitumor activity of phytic acid (inositol hexaphosphate) in murine transplanted and metastatic fibrosarcoma, a pilot study. Cancer Lett., 65, 9-13.
    • (1992) Cancer Lett. , vol.65 , pp. 9-13
    • Vucenik, I.1    Tomazic, V.J.2    Fabian, D.3    Shamsuddin, A.M.4
  • 25
    • 0031856814 scopus 로고    scopus 로고
    • Novel anticancer function of inositol hexaphosphate: Ihibition of human rhabdomyosarcoma in vitro and in vivo
    • Vucenik,I., Kalebic,T., Tantivejkul,K. and Shamsuddin,A.M. (1998) Novel anticancer function of inositol hexaphosphate: inhibition of human rhabdomyosarcoma in vitro and in vivo. Anticancer Res., 18, 1377-1384.
    • (1998) Anticancer Res. , vol.18 , pp. 1377-1384
    • Vucenik, I.1    Kalebic, T.2    Tantivejkul, K.3    Shamsuddin, A.M.4
  • 27
    • 0032217237 scopus 로고    scopus 로고
    • 6 regresses pre-existing human liver cancer xenotransplanted in nude mice
    • 6 regresses pre-existing human liver cancer xenotransplanted in nude mice. Anticancer Res., 18, 4091-4096.
    • (1998) Anticancer Res. , vol.18 , pp. 4091-4096
    • Vucenik, I.1    Zhang, Z.S.2    Shamsuddin, A.M.3
  • 29
    • 0027340038 scopus 로고
    • 3H]-PhytiC acid (inositol hexaphosphate) is absorbed and distributed to various tissues in rats
    • 3H]-PhytiC acid (inositol hexaphosphate) is absorbed and distributed to various tissues in rats. J. Nutr., 123, 713-720.
    • (1993) J. Nutr. , vol.123 , pp. 713-720
    • Sakamoto, K.1    Vucenik, I.2    Shamsuddin, A.M.3
  • 30
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman,J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Med., 1, 27-31.
    • (1995) Nature Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 31
    • 84975525035 scopus 로고
    • Clinical applications of research on angiogenesis
    • Folkman,J. (1995) Clinical applications of research on angiogenesis. N. Engl. J. Med., 333, 1757-1763.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1757-1763
    • Folkman, J.1
  • 32
    • 0034090097 scopus 로고    scopus 로고
    • Angiogenesis: Potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases and chronic inflammation
    • Griffioen,A.W. and Molema,G. (2000) Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases and chronic inflammation. Pharmacol. Rev., 52, 237-268.
    • (2000) Pharmacol. Rev. , vol.52 , pp. 237-268
    • Griffioen, A.W.1    Molema, G.2
  • 33
    • 0022648938 scopus 로고
    • How is blood vessel growth regulated in normal and neoplastic tissue?
    • Folkman,J. (1986) How is blood vessel growth regulated in normal and neoplastic tissue? Cancer Res., 46, 467-473.
    • (1986) Cancer Res. , vol.46 , pp. 467-473
    • Folkman, J.1
  • 34
    • 0035313488 scopus 로고    scopus 로고
    • FGF and VEGF function in angiogenesis: Signalling pathways, biological responses and therapeutic inhibition
    • Cross,M.J. and Claesson-Welsh,L. (2001) FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition. Trends Pharmacol. Sci., 22, 201-207.
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 201-207
    • Cross, M.J.1    Claesson-Welsh, L.2
  • 35
    • 0035525207 scopus 로고    scopus 로고
    • Angiogenesis inhibition in solid tumor
    • Rosen,L.S. (2001) Angiogenesis inhibition in solid tumor. Cancer J., 7 (suppl. 3), S120-S128.
    • (2001) Cancer J. , vol.7 , Issue.SUPPL. 3
    • Rosen, L.S.1
  • 39
    • 0025204095 scopus 로고
    • Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth
    • Ingber,D., Fujita,T., Kishimoto,S., Sudo,K., Kanamaru,T., Brem,H. and Folkman,J. (1990) Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth. Nature, 348, 555-557.
    • (1990) Nature , vol.348 , pp. 555-557
    • Ingber, D.1    Fujita, T.2    Kishimoto, S.3    Sudo, K.4    Kanamaru, T.5    Brem, H.6    Folkman, J.7
  • 40
    • 0033797806 scopus 로고    scopus 로고
    • Phase I dose escalation pharmacokinetics of O-(chloroacetylcarbamoyl) fumagillol (TNP-470) and its metabolites in AIDS patients with Kaposi's sarcoma
    • Moore,J.D., Dezube,B.J., Gill,P., Zhou,X.J., Acosta,E.P. and Sommadossi,J.P. (2000) Phase I dose escalation pharmacokinetics of O-(chloroacetylcarbamoyl) fumagillol (TNP-470) and its metabolites in AIDS patients with Kaposi's sarcoma. Cancer Chemother. Pharmacol., 46, 173-179.
    • (2000) Cancer Chemother. Pharmacol. , vol.46 , pp. 173-179
    • Moore, J.D.1    Dezube, B.J.2    Gill, P.3    Zhou, X.J.4    Acosta, E.P.5    Sommadossi, J.P.6
  • 43
    • 0034675269 scopus 로고    scopus 로고
    • Anti-angiogenic potential of a cancer chemopreventive flavonoid antioxidant, sylmarin: Inhibition of key attributes of vascular endothelial cells and angiogenic cytokine secretion by cancer epithelial cells
    • Jiang,C., Agarwal,R. and Lü,J. (2000) Anti-angiogenic potential of a cancer chemopreventive flavonoid antioxidant, sylmarin: inhibition of key attributes of vascular endothelial cells and angiogenic cytokine secretion by cancer epithelial cells. Biochem. Biophys. Res. Commun., 276, 371-378.
    • (2000) Biochem. Biophys. Res. Commun. , vol.276 , pp. 371-378
    • Jiang, C.1    Agarwal, R.2    Lü, J.3
  • 44
    • 0010115240 scopus 로고    scopus 로고
    • Anti-angiogenic activity of torilin, a sesquiterpene compound isolated from Torilis japonica
    • Kim,M.S., Lee,Y.M., Moon,E.-J., Kim,S.E., Lee,J.J. and Kim,K.-W. (2000) Anti-angiogenic activity of torilin, a sesquiterpene compound isolated from Torilis japonica. Int. J. Cancer, 87, 269-275.
    • (2000) Int. J. Cancer , vol.87 , pp. 269-275
    • Kim, M.S.1    Lee, Y.M.2    Moon, E.-J.3    Kim, S.E.4    Lee, J.J.5    Kim, K.-W.6
  • 45
    • 0035937335 scopus 로고    scopus 로고
    • EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells
    • Jung,Y.D., Kim,M.S., Chay,K.O., Ahn,B.W., Liu,W., Bucana,C.D., Gallick,G.E. and Ellis,L.M. (2001) EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells. Br. J. Cancer, 84, 844-850.
    • (2001) Br. J. Cancer , vol.84 , pp. 844-850
    • Jung, Y.D.1    Kim, M.S.2    Chay, K.O.3    Ahn, B.W.4    Liu, W.5    Bucana, C.D.6    Gallick, G.E.7    Ellis, L.M.8
  • 46
    • 0032445492 scopus 로고    scopus 로고
    • Vasostatin, a calreticulin fragment, inhibits angiogenesis and suppresses tumor growth
    • Pike,S.E., Yao,L., Jones,K.D. et al. (1998) Vasostatin, a calreticulin fragment, inhibits angiogenesis and suppresses tumor growth. J. Exp. Med., 188, 2349-2356.
    • (1998) J. Exp. Med. , vol.188 , pp. 2349-2356
    • Pike, S.E.1    Yao, L.2    Jones, K.D.3
  • 47
    • 0033214331 scopus 로고    scopus 로고
    • Calreticulin and calreticulin fragments are endothelial cell inhibitors that suppress tumor growth
    • Pike,S.E., Yao,L., Setsuda,J. et al. (1999) Calreticulin and calreticulin fragments are endothelial cell inhibitors that suppress tumor growth. Blood, 94, 2461-2468.
    • (1999) Blood , vol.94 , pp. 2461-2468
    • Pike, S.E.1    Yao, L.2    Setsuda, J.3
  • 48
    • 0034284301 scopus 로고    scopus 로고
    • Effective targeting of tumor vasculature by the angiogenesis inhibitors vasostatin and interleukin-12
    • Yao,L., Pike,S.E., Setsda,J., Parekh,J., Gupta,G., Raffeld,M., Jaffe,E.S. and Tosato,G. (2000) Effective targeting of tumor vasculature by the angiogenesis inhibitors vasostatin and interleukin-12. Blood, 96, 1900-1905.
    • (2000) Blood , vol.96 , pp. 1900-1905
    • Yao, L.1    Pike, S.E.2    Setsda, J.3    Parekh, J.4    Gupta, G.5    Raffeld, M.6    Jaffe, E.S.7    Tosato, G.8
  • 51
    • 0028981092 scopus 로고
    • The α-glucosidase I inhibitor castanospermine alters endothelial cell glycosylation, prevents angiogenesis and inhibits tumor growth
    • Pili,R., Chang,J., Partis,R.A., Mueller,R.A., Novick,T., Chrest,F.J. and Passaniti,A. (1995) The α-glucosidase I inhibitor castanospermine alters endothelial cell glycosylation, prevents angiogenesis and inhibits tumor growth. Cancer Res., 55, 2920-2926.
    • (1995) Cancer Res. , vol.55 , pp. 2920-2926
    • Pili, R.1    Chang, J.2    Partis, R.A.3    Mueller, R.A.4    Novick, T.5    Chrest, F.J.6    Passaniti, A.7
  • 52
    • 0026495179 scopus 로고
    • A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin and fibroblast growth factor
    • Passaniti,A., Taylor,R.M., Pili,R., Guo,Y., Long,P.V., Haney,J.A., Pauly,R.R., Grant,D.S. and Martin,G.R. (1992) A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin and fibroblast growth factor. Lab. Invest., 67, 519-528.
    • (1992) Lab. Invest. , vol.67 , pp. 519-528
    • Passaniti, A.1    Taylor, R.M.2    Pili, R.3    Guo, Y.4    Long, P.V.5    Haney, J.A.6    Pauly, R.R.7    Grant, D.S.8    Martin, G.R.9
  • 53
    • 0032919721 scopus 로고    scopus 로고
    • Expression of messenger ribonucleic acid splice variants for vascular endothelial growth factor in the penis of adult rats and humans
    • Burchardt,M., Burchardt,T., Chen,M.-W., Shabsigh,A., de la Taille,A., Buttyan,R. and Shagsigh,R. (1999) Expression of messenger ribonucleic acid splice variants for vascular endothelial growth factor in the penis of adult rats and humans. Biol. Reproduct., 60, 398-404.
    • (1999) Biol. Reproduct. , vol.60 , pp. 398-404
    • Burchardt, M.1    Burchardt, T.2    Chen, M.-W.3    Shabsigh, A.4    de la Taille, A.5    Buttyan, R.6    Shagsigh, R.7
  • 54
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou,T.-C. and Talalay,P. (1987) Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul., 22, 27-55.
    • (1987) Adv. Enzyme Regul. , vol.22 , pp. 27-55
    • Chou, T.-C.1    Talalay, P.2
  • 55
    • 0344244904 scopus 로고    scopus 로고
    • 6) inhibits key events of cancer metastasis: In vitro studies of adhesion, migration and invasion of MDA-MB 231 human breast cancer cells
    • 6) inhibits key events of cancer metastasis: In vitro studies of adhesion, migration and invasion of MDA-MB 231 human breast cancer cells. Anticancer Res., 23, 3671-3680.
    • (2003) Anticancer Res. , vol.23 , pp. 3671-3680
    • Tantivejkul, K.1    Vucenik, I.2    Shamsuddin, A.M.3
  • 58
    • 0036136731 scopus 로고    scopus 로고
    • Angioprevention: Angiogenesis is a common and key target for cancer chemopreventive agent
    • Tossetti,F., Ferrari,N., De Flora,S. and Albini,A. (2002) Angioprevention: angiogenesis is a common and key target for cancer chemopreventive agent. FASEB J., 16, 2-14.
    • (2002) FASEB J. , vol.16 , pp. 2-14
    • Tossetti, F.1    Ferrari, N.2    De Flora, S.3    Albini, A.4
  • 59
    • 0037360095 scopus 로고    scopus 로고
    • Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of prostate carcinoma DU145: Modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes
    • Singh,R.P., Agarwal,C. and Agarwal,R. (2003) Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of prostate carcinoma DU145: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes. Carcinogenesis, 24, 555-563.
    • (2003) Carcinogenesis , vol.24 , pp. 555-563
    • Singh, R.P.1    Agarwal, C.2    Agarwal, R.3
  • 60
    • 1642453720 scopus 로고    scopus 로고
    • In vivo suppression of hormone-refractory prostate cancer growth by inositol heaxaphosphate: Induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor
    • Singh,R.P., Sharma,G., Mallikarjuna,G.U., Dhanalakshmi,S., Agarwal,C. and Agarwal,R. (2004) In vivo suppression of hormone-refractory prostate cancer growth by inositol heaxaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor. Clin. Cancer Res., 10, 244-250.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 244-250
    • Singh, R.P.1    Sharma, G.2    Mallikarjuna, G.U.3    Dhanalakshmi, S.4    Agarwal, C.5    Agarwal, R.6
  • 62
    • 0031690845 scopus 로고    scopus 로고
    • Increased expression of vascular endothelial growth factor is associated with tumor progression in hepatocellular carcinoma
    • Torimura,T., Sata,M., Ueno,T., Kin,M., Tsuji,R., Suzaku,K., Hashimoto,O., Sugawara,H. and Tanikawa,K. (1998) Increased expression of vascular endothelial growth factor is associated with tumor progression in hepatocellular carcinoma. Hum. Pathol., 29, 986-991.
    • (1998) Hum. Pathol. , vol.29 , pp. 986-991
    • Torimura, T.1    Sata, M.2    Ueno, T.3    Kin, M.4    Tsuji, R.5    Suzaku, K.6    Hashimoto, O.7    Sugawara, H.8    Tanikawa, K.9
  • 63
    • 6844237654 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) mRNA isoform expression pattern is correlated with liver metastasis and poor prognosis in colon cancer
    • Tokunaga,T., Oshika,Y., Abe,Y. et al. (1998) Vascular endothelial growth factor (VEGF) mRNA isoform expression pattern is correlated with liver metastasis and poor prognosis in colon cancer. Br. J. Cancer, 77, 998-1002.
    • (1998) Br. J. Cancer , vol.77 , pp. 998-1002
    • Tokunaga, T.1    Oshika, Y.2    Abe, Y.3
  • 64
    • 0035477438 scopus 로고    scopus 로고
    • Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1a, HIF-2a and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/Akt signaling pathway
    • Blancher,C., Moore,J.W., Robertson,N. and Harris,A.L. (2001) Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1a, HIF-2a and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3′-kinase/Akt signaling pathway. Cancer Res., 61, 7349-7355.
    • (2001) Cancer Res. , vol.61 , pp. 7349-7355
    • Blancher, C.1    Moore, J.W.2    Robertson, N.3    Harris, A.L.4
  • 65
    • 0032541029 scopus 로고    scopus 로고
    • p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblast
    • Milanini,J., Vinals,F., Pouyssegur,J. and Pages,G. (1998) p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblast. J Biol. Chem., 273, 18165-18172.
    • (1998) J. Biol. Chem. , vol.273 , pp. 18165-18172
    • Milanini, J.1    Vinals, F.2    Pouyssegur, J.3    Pages, G.4
  • 66
    • 0033215389 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cell
    • Jung,Y.D., Nakano,K., Liu,W., Gallick,G.E. and Ellis,L.M. (1999) Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cell. Cancer Res., 59, 4804-4807.
    • (1999) Cancer Res. , vol.59 , pp. 4804-4807
    • Jung, Y.D.1    Nakano, K.2    Liu, W.3    Gallick, G.E.4    Ellis, L.M.5
  • 67
    • 0030793370 scopus 로고
    • Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphatidylinositol-3′ kinase
    • Huang,C., Ma,W.-Y., Hecht,S.S. and Dong,Z. (1977) Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphatidylinositol-3′ kinase. Cancer Res. 57, 2873-2878.
    • (1977) Cancer Res. , vol.57 , pp. 2873-2878
    • Huang, C.1    Ma, W.-Y.2    Hecht, S.S.3    Dong, Z.4
  • 68
    • 0034526276 scopus 로고    scopus 로고
    • Impairment of erbB1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells
    • Zi,X., Singh,R.P. and Agarwal,R. (2000) Impairment of erbB1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells. Carcinogenesis, 21, 2225-2235.
    • (2000) Carcinogenesis , vol.21 , pp. 2225-2235
    • Zi, X.1    Singh, R.P.2    Agarwal, R.3
  • 69
    • 0036964804 scopus 로고    scopus 로고
    • Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFκB-mediated cell survival pathway
    • Ferry,S., Matsuda,M., Yoshida,H. and Hirata,M. (2002) Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFκB-mediated cell survival pathway. Carcinogenesis, 23, 2031-2041.
    • (2002) Carcinogenesis , vol.23 , pp. 2031-2041
    • Ferry, S.1    Matsuda, M.2    Yoshida, H.3    Hirata, M.4
  • 70
    • 0037052641 scopus 로고    scopus 로고
    • Matrix metalloproteinases in cancer: Prognostic markers and therapeutic targets
    • Vihinen,P. and Kahari,V.M. (2002) Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets. Int. J. Cancer 99, 157-166.
    • (2002) Int. J. Cancer , vol.99 , pp. 157-166
    • Vihinen, P.1    Kahari, V.M.2
  • 71
    • 0028314275 scopus 로고
    • 6) and insulin-like growth factor II receptor binding sites in the rat brain
    • 6) and insulin-like growth factor II receptor binding sites in the rat brain. Neuroreport, 5, 625-628.
    • (1994) Neuroreport , vol.5 , pp. 625-628
    • Kar, S.1    Quirion, R.2    Parent, A.3
  • 72
    • 0031974197 scopus 로고    scopus 로고
    • Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma
    • Kim,K.W., Bae,S.K., Lee,O.K., Bae,M.H., Lee,M.J. and Park,B.C. (1998) Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma. Cancer Res., 58, 348-351.
    • (1998) Cancer Res. , vol.58 , pp. 348-351
    • Kim, K.W.1    Bae, S.K.2    Lee, O.K.3    Bae, M.H.4    Lee, M.J.5    Park, B.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.