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Volumn 46, Issue 3, 2000, Pages 173-179

Phase I dose escalation pharmacokinetics of O-(chloroacetylcarbamoyl) fumagillol (TNP-470) and its metabolites in AIDS patients with Kaposi's sarcoma

(6) Moore, Jeff D a Dezube, Bruce J b Gill, Parkash c Zhou, Xiao Jian a Acosta, Edward P a Sommadossi, Jean Pierre a

a UNIVERSITY OF ALABAMA AT BIRMINGHAM (United States)

b BETH ISRAEL DEACONESS MEDICAL CENTER (United States)

c UNIVERSITY OF SOUTHERN CALIFORNIA (United States)

Author keywords

Angiogenesis; Kaposi's sarcoma; Mass spectrometry; Metabolism; Pharmacokinetics; TNP 470

Indexed keywords

FUMAGILLOL CHLOROACETYLCARBAMATE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ANGIOGENESIS; AREA UNDER THE CURVE; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; DOSE CALCULATION; DRUG HALF LIFE; ENDOTHELIUM CELL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; KAPOSI SARCOMA; MALE; PHASE 1 CLINICAL TRIAL; PLASMA CLEARANCE; PRIORITY JOURNAL;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANGIOGENESIS INHIBITORS; ANTIBIOTICS, ANTINEOPLASTIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOHEXANES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INFUSIONS, INTRAVENOUS; MASS SPECTROMETRY; SARCOMA, KAPOSI; SENSITIVITY AND SPECIFICITY; SESQUITERPENES;

EID: 0033797806 PISSN: 03445704 EISSN: None Source Type: Journal
DOI: 10.1007/s002800000149 Document Type: Article

Times cited : (22)

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.