Novel anti-cancer functions of IP6: Growth inhibition and differentiation of human mammary cancer cell lines in vitro

Anticancer Research

Volumn 16, Issue 6 A, 1996, Pages 3287-3292

  Shamsuddin, Abulkalam M ^a   Yang, Guang Yu ^b   Vucenik, Ivana ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Cell proliferation; Chemoprevention; Phytate; Signal transduction

Indexed keywords

ESTROGEN RECEPTOR; LACTALBUMIN; PHYTIC ACID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DNA SYNTHESIS; DOSE RESPONSE; HIGH FIBER DIET; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL;

BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL DIVISION; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LACTALBUMIN; NEOPLASM PROTEINS; PHYTIC ACID; TUMOR CELLS, CULTURED;

EID: 0030499776     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Parker SL, Tong T, Bolden S and Wingo PA: Cancer statistics 1996, CA 46: 5-27, 1996.
2. Harland BF and Oberleas D: Phytate in foods. World Rev Nutr Diet 52: 235-259, 1987.
3. 6. Trends Biol Sci 18: 53-56, 1993.
4. Berridge MJ: Inositol trisphosphate and calcium signalling. Nature (Lend) 361: 315-325, 1993.
5. Elsayed A, Chakravarthy A and Shamsuddin A: Inositol hexaphosphate from corn decreased the frequency of colorectal cancer in azoxymethane treated rats. Lab Invest 56: 21A, 1987.
6. Rizzo MT and Weber G: 1-Phosphatidylinositol 4-kinase: An enzyme linked with proliferation and malignancy. Cancer Res 54: 2611-2614, 1994.
7. Singhal RL, Prajda N, Yeh A and Weber G: 1-Phosphatidylinositol 4-phosphate 5-kinase (EC 2.7.1.68): A proliferation- and malignancy-linked signal transduction enzyme. Cancer Res 54: 5574-5578, 1994.
8. Russo J, Gusterson BA, Rogers AE, Russo IH, Wellings SR and Zwieten MJV: Biology of disease. Comparative study of human and rat mammary tumorigenesis. Lab Invest 62: 244-278, 1990.
9. Kohn EC and Liotta LA: Molecular insights into cancer invasion: Strategies for prevention and intervention. Cancer Res 55: 1856-1862, 1995.
10. Zang EA, Barrett NO and Cohen LA: Differences in nutritional risk factors for breast cancer among New York City White, Hispanic, and Black college students. Ethnicity Dis 4: 28-40, 1994.