M2 muscarinic acetylcholine receptor knock-out mice show deficits in behavioral flexibility, working memory, and hippocampal plasticity

Journal of Neuroscience

Volumn 24, Issue 45, 2004, Pages 10117-10127

  Seeger, Thomas ^a   Fedorova, Irina ^b   Zheng, Fang ^c   Miyakawa, Tsuyoshi ^d   Koustova, Elena ^b   Gomeza, Jesus ^b   Basile, Anthony S ^b   Alzheimer, Christian ^a,c   Wess, Jürgen ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF KIEL   (Germany)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

Acetylcholine; Hippocampus; Knock out mice; Learning and memory; Long term potentiation; Muscarinic receptors; Synaptic plasticity

Indexed keywords

BICUCULLINE; MUSCARINIC AGENT; MUSCARINIC M2 RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR; CARBACHOL; GALLAMINE TRIETHIODIDE;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN SLICE; CONTROLLED STUDY; HIPPOCAMPUS; KNOCKOUT MOUSE; LEARNING; LONG TERM POTENTIATION; MAZE TEST; MOUSE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; STIMULUS RESPONSE; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION; WILD TYPE; WORKING MEMORY; AMNESIA; ANIMAL; ANIMAL BEHAVIOR; DRUG EFFECT; EXCITATORY POSTSYNAPTIC POTENTIAL; GENETICS; MALE; MEMORY; MOUSE MUTANT; PATCH CLAMP; PATHOPHYSIOLOGY; PHYSIOLOGY;

AMNESIA; ANIMALS; BEHAVIOR, ANIMAL; BICUCULLINE; CARBACHOL; EXCITATORY POSTSYNAPTIC POTENTIALS; GALLAMINE TRIETHIODIDE; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MEMORY; MICE; MICE, KNOCKOUT; MUSCARINIC AGONISTS; NEURONAL PLASTICITY; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RECEPTOR, MUSCARINIC M2; RECEPTORS, GABA-A;

EID: 8544262202     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3581-04.2004     Document Type: Article

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