Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice

Molecular Psychiatry

Volumn 8, Issue 7, 2003, Pages 673-679

  Tzavara, E T ^a   Bymaster, F P ^a   Felder, C C ^a   Wade, M ^a   Gomeza, J ^b   Wess, J ^b   McKinzie, D L ^a   Nomikos, G G ^a  

^a ELI LILLY AND COMPANY   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Acetylcholine; Hippocampus; Knockout mice; M2 M4 muscarinic; Microdialysis; Passive avoidance

Indexed keywords

ACETYLCHOLINE; AUTORECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M4 RECEPTOR; SCOPOLAMINE;

ACETYLCHOLINE BRAIN LEVEL; ACETYLCHOLINE RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLINERGIC SYSTEM; COGNITIVE DEFECT; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; HIPPOCAMPUS; HOMEOSTASIS; KNOCKOUT MOUSE; MALE; MEMORY CONSOLIDATION; MICRODIALYSIS; MOUSE; NEUROTRANSMISSION; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; TASK PERFORMANCE;

ACETYLCHOLINE; ANIMALS; AVOIDANCE LEARNING; COGNITION; CROSSES, GENETIC; ENVIRONMENT; HABITUATION, PSYCHOPHYSIOLOGIC; HIPPOCAMPUS; HOMEOSTASIS; MALE; MICE; MICE, KNOCKOUT; MICRODIALYSIS; MUSCARINIC ANTAGONISTS; RECEPTOR, MUSCARINIC M2; RECEPTOR, MUSCARINIC M4; SCOPOLAMINE; SYNAPTIC TRANSMISSION;

EID: 0042575347     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001270     Document Type: Article

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