Diffuse transmission by acetylcholine in the CNS

Progress in Neurobiology

Volumn 53, Issue 5, 1997, Pages 603-625

  Descarries, Laurent ^a   Gisiger, Victor ^a   Steriade, Mircea ^b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CHOLINERGIC RECEPTOR;

BRAIN CORTEX; BRAIN FUNCTION; CENTRAL NERVOUS SYSTEM; HIPPOCAMPUS; HUMAN; NEUROBIOLOGY; NEUROTRANSMISSION; PRIORITY JOURNAL; REVIEW; ULTRASTRUCTURE;

ACETYLCHOLINE; ANIMALS; BRAIN; CEREBRAL CORTEX; EXTRACELLULAR SPACE; HIPPOCAMPUS; NEOSTRIATUM; PRESYNAPTIC TERMINALS; SYNAPTIC TRANSMISSION;

EID: 0030664667     PISSN: 03010082     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-0082(97)00050-6     Document Type: Review

References (289)

1. Agnati, L. F., Zoli, M., Stromberg, I. and Fuxe, K. (1995) Intercellular communication in the brain: wiring versus volume transmission. Neuroscience 69, 711-726.
2. Ajima, A. and Kato, T. (1987) Brain dialysis: detection of acetylcholine in the striatum of unrestrained and unanesthetized rats. Neurosci. Lett. 81, 129-132.
3. Anderson, K. J., Gibbs, R. B.. Salvaterra, P. M. and Cotman. C. W. (1986) Ultrastructural characterization of identified cholinergic neurons transplanted to the hippocampal formation of the rat. J. Comp. Neurol. 249, 279-292.
4. André, C., Dos Santos, G. and Koulakoff, A. (1994) Muscarinic receptor profiles of mouse brain astrocytes in culture vary with their tissue of origin but differ from those of neurons. Eur. J. Neurosci. 6, 1702-1709.
5. Anglister, L., Stiles, J. R. and Salpeter, M. M. (1994) Acetylcholinesterase density and turnover number at frog neuromuscular junctions, with modeling of their role in synaptic function. Neuron 12, 783-794.
6. Aoki, C. (1992) β-adrenergic receptors: astrocytic localisation in the adult visual cortex and their relation to catecholamine axon terminals as revealed by electron microscopic immunocytochemistry. J. Neurosci. 12, 781-792.
7. Aoki, C. and Kabak, S. (1992) Cholinergic terminals in the cat visual cortex: ultrastructural basis for interaction with glutamate-immunoreactive neurons and other cells. Vis. Neurosci. 8, 177-191.
8. Appleyard, M. E. and Smith, A. D. (1987) Spontaneous and carbachol-evoked in vivo secretion of acetylcholinesterase from the hippocampus of the rat. Neurochem. Int. 11, 397-406.
9. Appleyard, M. E., Vercher, J.-L. and Greenfield, S. A. (1988) Release of acetylcholinesterase from the guinea-pig cerebellum in vivo. Neuroscience 25, 133-138.
10. Armstrong, D. M. (1986) Ultrastructural characterisation of choline acetyltransferase-containing neurons in the basal forebrain of rat: evidence for a cholinergic innervation of intracerebral blood vessels. J. Comp. Neurol. 250, 81-92.
11. Bach y Rita, P. (1993) Neurotransmission in the brain by diffusion through the extracellular fluid: a review. NeuroReport 4, 343-360.
12. Bach y Rita, P. (1994) The brain beyond the synapse: a review. NeuroReport 5, 1553-1557.
13. Bacou, F., Vigneron, P. and Massoulié, J. (1982) Acetylcholinesterase forms in fast end slow rabbit muscle. Nature 296, 661-664.
14. Bacou, F., Vigneron, P. and Couraud, J. Y. (1985) Retrograde effect of muscle on forms of acetylcholinesterase in peripheral nerves. J. Neurochem. 45, 1178-1185.
15. Bareggi, S. R. and Giacobini, E. (1978) Acetylcholinesterase activity in ventricular and cisternal CSF of dogs. J. Neurosci. Res. 3, 335-339.
16. Baude, A., Nusser, Z., Molnar, E., McIlhinney, R. A. and Somogyi, P. (1995) High-resolution immunogold localisation of AMPA type glutamate receptor subunits at synaptic and nonsynaptic sites in rat hippocampus. Neuroscience 69, 1031-1055.
17. Beaudet, A. and Descarries, L. (1978) The monoamine innervation of the cerebral cortex: synaptic and nonsynaptic axon terminals. Neuroscience 3, 851-860.
18. Beaudet, A. and Sotelo, C. (1981) Synaptic remodeling of serotonin axon terminals in rat agranular cerebellum. Brain Res. 206, 305-329.
19. Beaulieu, C. and Cynader, M. (1992) Preferential innervation of immunoreactive choline acetyltransferase synapses on relay cells of the cat's lateral geniculate nucleus: a double labeling study. Neuroscience 47, 33-44.
20. Beaulieu, C. and Somogyi. P. (1991) Enrichment of cholinergic synaptic terminals on GABAergic neurons and coexistence of immunoreactive GABA and choline acetyltransferase in the same synaptic terminals in the striate cortex of the cat. J. Comp. Neurol. 304, 666-680.
21. Behrends, J. C. and Ten Bruggencate, G. (1993) Cholinergic modulation of synaptic inhibition in the guinea pig hippocampus in vitro: excitation of GABAergic interneurons and inhibition of GABA-release. J. Neurophysiol. 69, 626-629.
22. Ben-Ari, Y., Krnjevic, K., Reinhardt, W. and Ropert, N. (1981) Intracellular observations on the disinhibitory action of acetylcholine in the hippocampus. Neuroscience 6, 2474-2484.
23. Bickford, M. E., Günlück, A. E., Guido, W. and Sherman, S. M. (1993) Evidence that cholinergic axons from the parabrachial region of the brainstem are the exclusive source of nitric oxide in the lateral geniculate nucleus of the cat. J. Comp. Neurol. 334, 410-430.
24. Blondet, B. and Gautron, J. (1980) Variation quantitative et localisation de 1'acetylcholinestérase dans le muscle dénervé du rat adulte. Biol. Cell 38, 203-210.
25. Boudreau-Larivière, C., Gisiger, V., Michel, R. N., Hubatsch, D. A. and Jasmin, B. J. (1997) Fast and slow skeletal muscles express a common basic profile of acetylcholinesterase molecular forms. Am. J. Physiol. 272(Cell Physiol. 41), C68-C76.
26. Brzin, M., Sketelj, J., Tennyson, V. M., Kiauta, T. and Budininkas-Schoenebeck, M. (1981) Activity, molecular forms and cytochemistry of cholinesterases in developing rat diaphragm. Muscle Nerve 4, 505-513.
27. Brzin, M., Sketelj, J. and Klinar, B. (1982) Cholinesterases. In: Handbook of Neurochemistry, 2nd edn, pp. 251-292. Ed. A. Lajtha. Plenum Press: New York.
28. Busch, C. and Sakmann, B. (1990) Synaptic transmission in hippocampal neurons: numerical reconstruction of quantal IPSCs. Cold Spring Harbor Symp. Quant. Biol. 55, 69-80.
29. Carlsen, J. and Heimer, L. (1986) A correlated light and electron microscopic immunocytochemical study of cholinergic terminals and neurons in the rat amygdaloid body with special emphasis on the basolateral amygdaloid nucleus. J. Comp. Neurol. 244, 121-136.
30. Chédotal, A., Umbriaco, D., Descarries, L., Hartman, B. K. and Hamel. E. (1994) Light and electron microscopic immunocytochemical analysis of the neurovascular relationships of choline acetyltransferase and vasoactive intestinal polypeptide nerve terminals in the rat cerebral cortex. J. Comp. Neurol. 343, 57-71.
31. Chubb, I. W., Goodman, S. and Smith, A. D. (1976) Is acetylcholinesterase secreted from central neurons into the cerebrospinal fluid? Neuroscience 1, 57-62.
32. Clarençon, D., Testylier, G., Estrade, M., Galonnier, M., Viret, J., Gourmelon, P. and Fatome, M. (1993) Stimulated release of acetylcholinesterase in rat striatum revealed by in vivo microspectrophotometry. Neuroscience 55, 457-462.
33. Clarke, D. J. (1985) Cholinergic innervation of the rat dentate gyrus: an immunocytochemical and electron microscopical study. Brain Res. 360, 349-354.
34. Clarke, P. B. S. (1993) Nicotinic receptors in mammalian brain: localisation and relation to cholinergic innervation. Prog. Brain Res. 98, 77-83.
35. Clarke, D. J. and Dunnett, S. B. (1986) Ultrastructural organisation of choline acetyltransferase-immunoreactive fibres innervating the neocortex from embryonic ventral forebrain grafts. J. Comp. Neurol. 250, 192-205.
36. 3H]dopamine release. Br. J. Pharmacol. 117, 595-606.
37. Clements, J. D. (1996) Transmitter time course in the synaptic cleft: its role in central synaptic function. Trends Neurosci. 19, 163-171.
38. Clements, J. D., Lester, R. A., Tong, G., Jahr, C. E. and Westbrook, G. L. (1992) The time course of glutamate in the synaptic cleft. Science 258, 1498-1501.
39. Cohen, Z., Bonvento, G., Lacombe, P. and Hamel, E. (1996) Serotonin in the regulation of brain microcirculation. Prog. Neurobiol. 50, 335-362.
40. Contant, C., Umbriaco, D., Garcia, S., Watkins, K. C. and Descarries, L. (1996) Ultrastructural characterisation of the acetylcholine innervation in adult rat neostriatum. Neuroscience 71, 937-947.
41. Couteaux, R. and Nachmansohn, D. (1940) Changes of choline esterase at endplates of voluntary muscle following section of sciatic nerve. Proc. Soc. Exp. Biol. Med. 43, 177-181.
42. Crawford, G. D., Correa, L. and Salvaterra, P. M. (1982) Interaction of monoclonal antibodies with mammalian choline acetyltransferase. Proc. Natl. Acad. Sci. U.S.A. 79, 7031-7035.
43. Cresnar, B., Crne-Finderle, N., Breskvar, K. and Sketelj, J. (1994) Neural regulation of muscle acetylcholinesterase is exerted on the level of its mRNA. J. Neurosci. Res. 38, 294-299.
44. Cuadra, G., Summers, K. and Giacobini, E. (1994) Cholinesterase inhibitor effects on neurotransmitters in rat cortex in viro. J. Pharmacol. Exp. Ther. 270, 277-284.
45. Cudeiro, J., Rivadulla, C., Rodriguez, R., Martinez-Conde, S., Grieve, K. L. and Acuña, C. (1996) Further observations on the role of nitric oxide in the feline lateral geniculate nucleus. Eur. J. Neurosci. 8, 144-152.
46. Cuello. A. C. (1982) Nonclassical neuronal communication. Fedn Proc. 42, 2912-2922.
47. Dally. J. J. and Greenfield, S. A. (1994) The release of acetylcholinesterase in vivo is regulated by dopaminergic systems in the guinea-pig substantia nigra. Neurochem. Int. 25, 339-344.
48. Dally, J. J., Schaeffer, M. and Greenfield, S. A. (1996) The spontaneous release of acetylcholinesterase in rat substantia nigra is altered by local changes in extracellular levels of dopamine. Neurochem. Int. 29, 629-635.
49. Damsma, G., Westerink, B. H. C., deBoer, P., deVries, J. B. and Horn, A. S. (1988) Basal acetylcholine release in freely moving rats detected by on-line trans-striatal dialysis: pharmacological aspects. Life Sci. 43, 1161-1168.
50. Davis, R. and Koelle, G. B. (1978) Electron microscope localisation of acetylcholinesterase and butyrylcholinesterase in the superior cervical ganglion of the cat. I. Normal ganglion. J. Cell Biol. 78, 785-809.
51. deBoer, P., Westerink, B. H. C. and Horn, A. S. (1990) The effect of acetylcholinesterase inhibition on the release of acetylcholine from the striatum in vivo: interaction with autoreceptor responses. Neurosci. Lett. 116, 357-360.
52. De Klippel, N., Sarre, S., Ebinger, G. and Michotte, Y. (1993) Effect of M1-and M2-muscarinic drugs on striatal dopamine release and metabolism: an in vivo microdialysis study comparing normal and 6-hydroxydopamine-lesioned rats. Brain Res. 630, 57-64.
53. De Lima, A. D. and Singer, W. (1986) Cholinergic innervation of the cat striate cortex: a choline acetyltransferase immunocytochemical analysis. J. Comp. Neural. 250, 324-338.
54. De Lima. A. D., Montero, V. M. and Singer, W. (1985) The cholinergic innervation of the visual thalamus: an EM immunocytochemical analysis. Exp. Brain Res. 59, 206-212.
55. De Sarno, P., Giacobini, E. and Downen, M. (1987) Release of acetylcholinesterase from the caudate nucleus of the rat. J. Neurosci. Res. 18, 578-590.
56. Descarries. L, and Umbriaco, D. (1995) Ultrastructural basis of monoamine and acetylcholine function in CNS. Semin. Neurosci. 7, 309-318.
57. Descarries, L., Beaudet, A. and Watkins, K. C. (1975) Serotonin nerve terminals in adult rat neocortex. Brain Res. 100, 563-588.
58. Descarries, L., Watkins, K. C. and Lapierre, Y. (1977) Noradrenergic axon terminals in the cerebral cortex of rat - III. Topometric ultrastructural analysis. Brain Res. 133, 197-222.
59. Descarries, L., Séguéla, P. and Watkins, K. C. (1991) Nonjunctional relationships of monoamine axon terminals in the cerebral cortex of adult rat. In: Volume Transmission in the Brain: Novel Mechanisms for Neural Transmission, pp. 53-62. Eds K. Fuxe and L. F. Agnati. Raven Press: New York.
60. Descarries, L., Umbriaco, D., Contant, C. and Watkins, K. C. (1995) A new hypothesis of acetylcholine (ACh) function in densely ACh-innervated regions of the brain. IVth IBRO World Congr. Neurosci. Abstr. A3.15, pp. 101.
61. DiFiglia, M. (1987) Synaptic organisation of cholinergic neurons in the monkey neostriatum. J. Comp. Neurol. 255, 245-258.
62. Dismukes, R. K. (1979) New concepts of molecular communication among neurons. Behav. Brain Sci. 2, 409-448.
63. Do, K. Q., Binns, K. E. and Salt, T. E. (1994) Release of the nitric oxide precursor, arginine, from the thalamus upon sensory affer-ent stimulation and its effect on thalamic neurons in vivo. Neuroscience 60, 581-586.
64. + concentrations. Naunyn-Schmiedeberg's Arch. Pharmacol. 348, 228-233.
65. Dorlöchter, M., Irintchev, A., Brinkers, M. and Wernig, A. (1991) Effects of enhanced activity on synaptic transmission in mouse extensor digitorum longus muscle. J. Physiol., Lond. 436, 283-292.
66. Doucet, G., Descarries, L. and Garcia, S. (1986) Quantification of the dopamine innervation in adult rat neostriatum. Neuroscience 19, 427-445.
67. Dutar, P. and Nicoll, R. A. (1988) Classification of muscarinic responses in hippocampus in terms of receptor subtypes and 2nd-messenger systems: electrophysiological studies in vitro. J. Neurosci. 8, 4214-4224.
68. Dykes, R. W. (1990) Acetylcholine and neuronal plastivity in somatosensory cortex. In: Brain Cholinergic Systems, pp. 294-313. Eds M. Steriade and D. Biesold. Oxford University Press: Oxford, New York.
69. Eccles, J. C. (1944) The nature of synaptic transmission in a sympathetic ganglion. J. Physiol., Lond. 103, 27-54.
70. Eccles, J. C. (1964) The Physiology of Synapses. Academic Press, New York.
71. Eccles, J. C. and Jaeger, J. C. (1958) The relationship between the mode of operation and the dimensions of the junctional regions at synapses and motor end-organs. Proc. R. Soc. Lond. B 148, 38-56.
72. Eckenstein, F. and Baughman, R. W. (1987) Cholinergic innervation in cerebral cortex. In: Cerebral Cortex, Further Aspects of Cortical Function, Including Hippocampus, Vol. 6, pp. 129-160. Eds E. G. Jones and A. Peters. Plenum Press: New York.
73. Eckenstein, F. and Thoenen, H. (1982) Production of specific antisera and monoclonal antibodies to cholire acetyltransferase: characterisation and use for identification of cholinergic neurons. EMBO J. 1, 363-368.
74. Edvinsson, L., MacKenzie, E. T. and McCulloch, J. (1993) Cerebral Blood Flow and Metabolism, Chap. 3.4, Acetylcholine, pp. 285-312. Raven Press: New York.
75. Emmelin, N. and MacIntosh, F. C. (1956) The release of acetylcholine from perfused sympathetic ganglia and skeletal muscles. J. Physiol., Lond. 131,477-496.
76. Faber, D. S., Young, W. S., Legendre, P. and Korn, H. (1992) Intrinsic quantal variability due to stochastic properties of receptor-transmitter interactions. Science 258, 1494-1498.
77. 4 AChE activity in fast-twitch muscle. J. Appl. Physiol. 65, 2245-2252.
78. Fernandez, H. L. and Seiter, T. C. (1984) Subcellular distribution of acetylcholinesterase asymmetric forms during postnatal development of mammalian skeletal muscle. FEBS Lett. 170, 147-151.
79. 4) acetylcholinesterase: structure, localisation, and physiological regulation. J. Neurochem. 66, 1335-1346.
80. Flores, C. M., Rogers, S. W., Pabreza, L. A., Wolfe, B. B. and Kellar, K. J. (1992) A subtype of nicotinic cholinergic receptors in rat brain is composed of α4 and β2 subunits and is upregulated by chronic nicotine treatment. Mol. Pharmacol. 41, 31-37.
81. 3 H]acetylcholine release from rat hippocampus. J. Neurochem. 54, 1386-1390.
82. Fredholm, B. B. (1993) Presynaptic regulation of hippocampal acetylcholine release is unaffected by calcium channel blockers and intracellular calcium chelation. Acta Physiol. Scand. 147, 461-463.
83. Frotscher, M. (1989) Central Cholinergic synapses: the septohippocampal system as a model. In: Experientia Supplementum : Central Cholinergic Synaptic Transmission, Vol. 57, pp. 33-41. Eds M. Frotscher and U. Misgeld. Birkhaüser: Basel.
84. Frotscher, M. (1992) Application of the Golgi/electron microscopy technique for cell identification in immunocytochemical, retrogrrade labeling, and developmental studies of hippocampal neurons. Microsc. Res. Tech. 23, 306-323.
85. Frotscher, M. and Léránth, C. (1985) Cholinergic innervation of the rat hippocampus as revealed by choline acetyltransferase immunocytochemistry: a combined light and electron microscopic study. J. Comp. Neurol. 239, 237-246.
86. Frotscher, M. and Léránth, C. (1986) The cholinergic innervation of the rat fascia dentata: identification of target structures on granule cells by combining choline acetyltransferase immunocytochemistry and Golgi impregnation. J. Comp. Neurol. 243, 58-70.
87. Frotscher, M., Soriano, E. and Léránth, C. (1992) Cholinergic and GABAergic neurotransmission in the fascia dentate: electron microscopic immunocytochemical studies in rodents and primates. Epilepsy Res. (suppl. 7), 65-78.
88. Fuxe, K. and Agnati, L. F. (1991) Two principal modes of electrochemical communication in the brain: volume versus wiring transmission. In: Volume Transmission in the Brain: Novel Mechanisms for Neural Transmission, pp. 1-9. Eds K. Fuxe and L. F. Agnati. Raven Press: New York.
89. Garcia-Villalon, A. L, Krause, D. N., Ehlert, F. J. and Duckles, S. P. (1991) Heterogeneity of muscarinic receptor subtypes in cerebral blood vessels. J. Pharmacol. Exp. Ther. 258, 304-310.
90. Gardiner, P. F., Favron, M. and Corriveau, P. (1992) Histochemical and contractile responses of rat medial gastrocnemius to 2 weeks of complete disuse. Can. J. Physiol. Pharmacol. 70, 1075-1081.
91. Garofalo, L., Ribeiro-Da-Silva, A. and Cuello, A. C. (1992) Nerve growth factor-induced synaptogenesis and hypertrophy of cortical Cholinergic terminals. Proc. Natl. Acad. Sci. U.S.A. 89, 2639-2643.
92. Garofalo, L., Ribeiro-Da-Silva, A. and Cuello, A. C. (1993) Potentiation of nerve growth factor-induced alterations in cholinergic fiber length and presynaptic terminal size in cortex of lesioned rats by the monosialoganglioside GM1. Neuroscience 57, 21-40.
93. Gautron, J. and Gisiger, V. (1976) Effet de la section du nerf préganglionnaire sur la localisation de l'acétylcholinestérase du ganglion cervical supérieur du rat. C.R. Acad. Sci., Paris 283, 1505-1507.
94. Gisiger, V. (1995) Dual control of acetylcholinesterase content of mature innervated fast muscles, In: Enzymes of the Cholinesterase Family, pp. 233-237. Eds D. M. Quinn, A. S. Balasubramanian, B. P. Doctor and P. Taylor. Plenum Press: New York and London.
95. Gisiger, V. and Stephens, H. R. (1982) Acetylcholinesterase content in both motor nerve and muscle is correlated with twitch properties. Neurosci. Lett. 31, 301-305.
96. Gisiger, V. and Stephens, H. R. (1982-83) Correlation between the acetylcholinesterase content in motor nerves and their muscles. Gif Lectures in Neurobiology, J. Physiol. (Paris) 7, 720-728.
97. Gisiger, V. and Stephens, H. R. (1983) Asymmetric and globular forms of AChE in slow and fast muscles of 129/ReJ normal and dystrophic mice. J. Neurochem. 41, 919-929.
98. 4 (IOS) acetylcholinesterase content in motor nerves to fast muscles of dystrophic 129/ ReJ mice: lack of a specific compartment of nerve acetylcholinesterase? J. Neurochem. 43, 174-183.
99. 4 acetylcholinesterase characterising fast muscles and its alteration in marine muscular dystrophy. J. Neurosci. Res. 19, 62-78.
100. Gisiger, V. and Vigny, M. (1977) A specific form of acetylcholinesterase is secreted by rat sympathetic ganglia. FEBS Lett. 84, 253-256.
101. Gisiger, V., Venkov, L. and Gautron, J. (1975) Acetylcholinesterase and biosynthesis of proteins in the resting and stimulated sympathetic ganglion. J. Neurochem. 26, 737-748.
102. Gisiger, V., Vigny, M., Gautron, J. and Rieger, F. (1978) Acetylcholinesterase of rat sympathetic ganglion: molecular forms, localization and effects of denervation. J. Neurochem. 30, 501-516.
103. 4 acetylcholinesterase content of both fast ankle extensors and flexors. FEBS Lett. 278, 271-273.
104. 4 acetylcholinesterase characterising rodent fast muscles is differentially regulated by the predominant type. dynamic or tonic, of natural activity. In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology, pp. 81-85. Eds J. Massoulié, F. Bacou, E. Barnard, A. Chatonnet, B. Doctor and M. D. Quinn. ACS Conference Proceedings Series: Washington.
105. Gisiger, V., Bélisle, M. and Gardiner, P. F. (1994) Acetylcholinesterase adaptation to voluntary wheel running is proportional to the volume of activity in fast, but not slow, rat hindlimb muscles. Eur. J. Neurosci. 6, 673-680.
106. Granbacher, N. (1971) Relation between the size of muscle fibers, motor endplates and nerve fibers during hypertrophy and atrophy. Z. Anat. Entw Gesch. 135, 76-87.
107. Greaney, M. D., Marshall, D. L., Bailey, B. A. and Acworth, I. N. (1993) Improved method for the routine analysis of acetylcholine release in vivo: quantitation in the presence and absence of esterase inhibitor. J. Chromatogr. 622, 125-135.
108. Greenfield, S. A. (1985) The significance of dendritic release of transmitter and protein in the substantia nigra. Neurochem. Int. 7, 887-901.
109. Greenfield, S. A. and Smith, D. (1979) The influence of electrical stimulation of certain brain regions on the concentration of acetylcholinesterase in rabbit cerebrospinal fluid. Brain Res. 177, 445-459.
110. Greenfield, S. A., Cheramy, A., Leviel, V. and Glowinski, J. (1980) In vivo release of acetylcholinesterase in cat substantia nigra and caudate nucleus. Nature 284, 355-357.
111. Groswald, D. E. and Dettbarn, W. D. (1983) Characterization of acetylcholinesterase molecular forms in slow and fast muscle of rat. Neurochem. Res. 8, 983-995.
112. Guth, L., Albers, R. W. and Brown, W. C. (1964) Quantitative changes in cholinesterase activity of denervated muscle fibers and sole plates. Exp. Neurol. 10, 236-250.
113. Hallanger, A. E. and Wainer, B. H. (1988) Ultrastructure of ChAT-immunoreactive synaptic terminals in the thalamic reticular nucleus of the rat. J. Comp. Neurol. 278, 486-497.
114. Hallanger, A. E., Price, S. D., Lee, H. J., Steininger, T. L. and Wainer, B. H. (1990) Ultrastructure of cholinergic synaptic terminals in the thalamic anteroventral, ventroposterior, and dorsal lateral geniculate nuclei of the rat. J. Comp. Neurol. 299, 482-492.
115. Hansson, E. (1991) Transmitter receptors on astroglial cells. In: Volume Transmission in the Brain: Novel Mechanisms for Neural Transmission, pp. 257-265. Eds K. Fuxe and L. F. Agnati. Raven Press: New York.
116. Hasselmo, M. E. and Bower, J. M. (1992) Cholinergic suppression specific to intrinsic not afferent fiber synapses in rat piriform (olfactory) cortex. J. Neurophysiol. 67, 1222-1229.
117. Hasselmo, M. E. and Schnell, E. (1994) Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CAT: computational modeling and brain slice physiology. J. Neurosci. 14, 3898-3914.
118. Henderson, Z. (1989) Acetylcholinesterase on the deridrites of central cholinergic neurons: an electron microscopical study in the ferret. Neuroscience 28, 95-108.
119. Henderson. Z. and Greenfield, S. A. (1984) Ultrastructural localization of acetylcholinesterase in substantia nigra: a comparison between rat and guinea pig. J. Comp. Neurol. 230, 278-286.
120. Herkenham, M. (1987) Mismatches between neurotransmitter and receptor localization in brain: observations and implications. Neuroscience 23, 1-38.
121. Hersh, S. M., Gutekunnst, C. -A., Rees, H. D., Heilman, C. J. and Levey, A. I. (1994) Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies. J. Neurosci. 14, 3351-3363.
122. Hill, J. A., Zoli, M., Bourgeois, J. P. and Changeux, J. P. (1993) Immunocytochemical localisation of a neuronal nicotinic receptor: the β2-subunit. J. Neurosci. 13, 1551-1568.
123. Hösli, E. and Hösli, L. (1993) Receptors for neurotransmitters on astrocytes in the mammalian central nervous system. Prog. Neurobiol. 40, 477-506.
124. Hounsgaard, J. (1978) Presynaptic inhibitory action of acetylcholine in area CA1 of the hippocampus. Exp. Neurol. 62, 787-797.
125. Houser, C. R. (1990) Cholinergic synapses in the central nervous system: studies of the immunocytochemical localisation of choline acetyltransferase. J. Electron Microsc. Tech. 15, 2-19.
126. Houser, C. R., Crawford, G. D., Salvaterra, P. M. and Vaughn, J. E. (1985) Immunocytochemical localisation of choline acetyltransferase in rat cerebral cortex: a study of cholinergic neurons and synapses. J. Comp. Neurol. 234, 17-34.
127. Hu, B., Steriade, M. and Deschênes, M. (1989) The effects of brain-stem peribrachial stimulation on neurons of the lateral geniculate nucleus. Neuroscience 31, 13-24.
128. Huang, T., Yang, L., Gitzen, J., Kissinger, P. T., Vreeke, M. and Heller, A. (1995) Detection of basal acetylcholine in rat brain microdialysate. J. Chromatogr. B. 670, 323-327.
129. Isaacson, L. G. and Tanaka, D. J. (1988) Cholinergic innervation of canine thalamocortical projection neurons: an ultrastructural study combining choline acetyltransferase immunocytochemistry with WGA-HRP retrograde labeling. J. Comp. Neurol. 277, 529-540.
130. Isaacson, J. S., Solis, J. M. and Nicoll, R. A. (1993) Local and diffuse synaptic actions of GABA in the hippocampus. Neuron 10, 165-175.
131. Izzo, P. N. and Bolam, J. P. (1988) Cholinergic synaptic input to different parts of spiny striatonigral neurons in the rat. J. Comp. Neurol. 269, 219-234.
132. 3H]dopamine from rat prefrontal cortex: modulation through presynaptic cholinergic heteroreceptors. Neurosci. Lett. 106, 189-194.
133. James, M. K. and Cubeddu, L. X. (1984) Frequency-dependent muscarinic receptor modulation of acetylcholine and dopamine release from rabbit striatum. J. Pharmacol. Exp. Ther. 229, 98-104.
134. 4 acetylcholinesterase characterizing fast muscles: opposite effect of running training in antagonist muscles. J. Neurosci. 10, 1444-1454.
135. Jasmin, B. J., Gardiner, P. F. and Gisiger, V. (1991) Muscle acetylcholinesterase adapts to compensatory overload by a general increase in its molecular forms. J. Appl. Physiol. 70, 2485-2489.
136. Jasmin, B. J., Lee, R. K. and Rotundo, R. L. (1993) Compartimentalization of acetylcholinesterase mRNA and enzyme at the vertebrate neuromuscular junction. Neuron 11, 467-477.
137. Kahnin, R., Parnas, H. and Segel, L. (1994) Diffusion cannot govern the discharge of neurotransmitter in fast synapses. Biophys. J. 67, 966-972.
138. Kalaria, R. N., Homayoun, P. and Whitehouse, P. J. (1994) Nicotinic cholinergic receptors associated with mammalian cerebral vessels. J. Auton. Nerv. Syst. 49, S3-S7.
139. Kasa, P., Hlavati, I., Dobo, E., Wolff, A., Joo, F. and Wolff, J. R. (1995) Synaptic and non-synaptic cholinergic innervation of the various types of neurons in the main olfactory bulb of adult rat: immunocytochemistry of choline acetyltransferase. Neuroscience 67, 667-677.
140. Kasa, P., Karcsu, S., Kovacs, I. and Wolff, J. R. (1996) Cholinoceptive neurons without acetylcholinesterase activity and enzyme-positive neurons without cholinergic synaptic innervation are present in the main olfactory bulb of adult rat. Neuroscience 73, 831-844.
141. 3H]acetylcholine to muscarinic cholinergic receptors. J. Neurosci. 5, 1577-1582.
142. Klinar, B. and Brzin, M. (1977) Cytochemical localization of acetylcholinesterase in the rat striatum. Acta Histochem. 59, 223-231.
143. Kosasa, T., Yamanishi, Y., Ogura, H. and Yamatsu, K. (1990) Effects of E2020 on the extracellular level of acetylcholine in the rat cerebral cortex measured by microdialysis without the addition of cholinesterase inhibitor. Eur. J. Pharmacol. 183, 1936.
144. Kremzner, L. T., Kitz, R. J. and Ginsburg, S. (1967) A partial purification and characterization of the acetylcholinesterase of human brain. Fedn Proc. 26, 296.
145. Kreutzberg, G. W. and Tóth, L. (1974) Dendritic secretion: a way for the neurone to communicate with the vasculature. Naturwissenschaften 61, 37.
146. Krnjevic, K., Pumain, R. and Renaud, L. (1971) The mechanism of excitation by acetylcholine in the cerebral cortex. J. Physiol., Lond. 215, 247-268.
147. Kullmann, D. M., Erdemli, G. and Asztély, F. (1996) LTP of AMPA and NMDA receptor-mediated signals: evidence for pre-synaptic expression and extrasynaptic glutamate spill-over. Neuron 17,461-474.
148. Kupfermann, I. (1979) Modulatory actions of neurotransmitters. Annu. Rev. Neurosci. 2, 447-465.
149. Kuroda, M. and Price, J. L. (1991a) Synaptic organization of projections from basal forebrain structures to the mediodorsal thalamic nucleus of the rat. J. Comp. Neurol. 303, 513-533.
150. Kuroda, M. and Price, J. L. (I991b) Ultrastructure and synaptic organisation of axon terminals from brainstem structures to the mediodorsal thalamic nucleus of the rat. J. Comp. Neurol. 313, 539-552.
151. Legay, C., Bon, S., Vernier, P., Coussen, F. and Massoulié, J. (1993) Cloning and expression of a rat acetylcholinesterase subunit: generation of multiple molecular forms and complementarity with a Torpedo collagenic subunit. J. Neurochem. 60, 337-346.
152. Legay, C., Hucher, M., Massoulié, J. and Changeux, J. -P. (1995) Developmental regulation of acetylcholinesterase transcripts in the mouse diaphragm: alternative splicing and focalization. Eur. J. Neurosci. 7, 1803-1809.
153. 2- ions in nicotinic facilitation of GABA release in mouse thalamus. J. Neurosci. 17, 576-585.
154. Léna, C., Changeux, J. -P. and Mulle, C. (1993) Evidence for "pre-terminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus. J. Neurosci. 13, 2680-2688.
155. Léránth, C. and Frotscher, M. (1987) Cholinergic innervation of hippocampal GAD and somatostatin-immunoreactive commissural neurons. J. Comp. Neurol. 261, 33-47.
156. Levey, A. I., Armstrong. D. M., Atweh, S. F., Terry, R. D. and Wainer, B. H. (1983) Monoclonal antibodies to choline acetyltransferase: production, specificity, and immunohistochemistry. J. Neurosci. 3, 1-9.
157. Levey, A. I., Edmunds, S. M., Hersch, S. M., Wiley, R. G. and Heilman, C. J. (1995) Light and electron microscopic study of m2 muscarinic acetylcholine receptor in the basal forebrain of the rat. J. Comp. Neurol. 351, 339-356.
158. Linville, D. G. and Hamel, E. (1995) Pharmacological characterization of muscarinic acetylcholine binding sites in human and bovine cerebral microvessels. Naunyn-Schmiedeberg's Arch. Pharmacol. 352, 179-186.
159. Liu, J. K. and Kato, T. (1994) Effect of physostigmine on relative acetylcholine output induced by systemic treatment with scopolamine in in vivo microdialysis of rat frontal cortex. Neurochem. Int. 24. 589-596.
160. Llinás, R. R. and Greenfield, S. A. (1987) On-line visualisation of dendritic release of acetylcholinesterase from mammalian substantia nigra neurons. Proc. Natl. Acad. Sci. U.S.A. 84, 3047-3050.
161. Lomo, T., Massoulié, J. and Vigny, M. (1985) Stimulation of denervated rat soleus muscle with fast and slow activity patterns induces different expression of acetylcholinesterase molecular forms. J. Neurosci. 5, 1180-1187.
162. Lönnroth. P., Jansson, P. A. and Smith, U. (1987) A microdialysis method allowing characterization of intercellular water space in humans. Am. J. Physiol. 253, E228-E231.
163. Lönnroth, P., Jansson, P. A., Fredholm, B. B. and Smith, U. (1989) Microdialysis of intercellular adenosine concentration in subcutaneous tissue in humans. Am. J. Physiol. 256, E250-E255.
164. Lucas, C. A. and Kreutzberg, G. W. (1985) Regulation of acetylcholinesterase secretion from neuronal cell cultures. I. Actions of nerve growth factor, cytoskelelal inhibitors and tunicamycin. Neuroscience 14, 349-360.
165. Marchi, M. and Raiteri, M. (1996) Nicotinic autoreceptors mediating enhancement of acetylcholine release become operative in conditions of "impaired" cholinergic presynaptic function. J. Neurochem. 67, 1974-1981.
166. Marchi, M., Paudice, P. and Raiteri, M. (1981) Autoregulation of acetylcholine release in isolated nerve endings. Eur. J. Pharmacol. 73, 75-79.
167. 2 muscarinic receptors in the rat brain. Neuroscience 19, 551-564.
168. Massoulié, J., Pezzementi, L., Bon, S., Krejci, E. and Vallette, F. M. (1993) Molecular and cellular biology of cholinesterases. Prog. Neurobiol. 41, 31-91.
169. Massoulié, J., Legay, C., Anselmet, A., Krejci, E., Goussen, F. and Bon, S. (1996) Biosynthesis and integration of actylcholinesterase in the cholinergic synapse. Prog. Brain Res. 109, 55-65.
170. Matthews, D. A., Salvaterra, P. M., Crawford, G. D., Houser, C. R. and Vaughn, J. E. (1987) An immunocytochemical study of choline acetyltransferase-containing neurons and axon terminals in normal and partially deafferented hippocampal formation. Brain Res. 402, 30-43.
171. Matthews-Bellinger, J. and Salpeter, M. M. (1978) Distribution of acetylcholine receptors at frog neuromuscular junctions with a discussion of some physiological implications. J. Physiol. 279, 197-213.
172. 1B receptors mediating inhibition of acetylcholine. Eur. J. Pharmacol. 129, 333-337.
173. McCaman, M. W., Stafford, M. L. and Skinner, E. C. (1967) Choline acetyltransferase and cholinesterase activities in muscle of dystrophic mice. Am. J. Physiol. 212, 228-232.
174. McCormick, D. A. (1992) Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity. Prog. Neurobiol. 39, 337-388.
175. McCormick, D. A. and Pape, H.-C. (1990) Properties of a hyperpolarizalion-activated cation current and its role in rhythmic oscillation in thalamic relay neurones. J. Physiol., Lond. 431, 291-318.
176. McCormick, D. A. and Prince, D. A. (1987) Actions of acetylcholine in the guinea pig and cat medial and lateral geniculate nuclei, in vitro. J. Physiol., Lond. 392, 147-165.
177. McGehee, D. S. and Role, L. W. (1995) Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annu. Rer. Physiol. 57, 521-546.
178. McGehee, D. S., Heath, M. J., Gelber, S., Devay, P. and Role. L. W. (1995) Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science 269, 1692-1696.
179. Messamore, E., Ogane, N. and Giacobini, E. (I993a) Cholinesterase inhibitor effects on extracellular acetylcholine in rat striatum. Neutropharmacology 32, 291-296.
180. Messamore, E., Warpman, U., Ogane, N. and Giacobini, E. (1993b) Cholinesterase inhibitor effects on extracellular acetylcholine in rat cortex. Neuropharmacology 32, 745-760.
181. Metherate, R. and Asche, J. H. (1992) Cellular bases of neocortical activation: modulation of neural oscillations by the nucleus basalis and endogenous acetylcholine. J. Neurosci. 12, 4701-4711.
182. Metherate, R. and Asche. J. H. (1993) Ionic flux contributions to neocortical slow waves and nucleus basalis-mediated activation: whole-cell recordings in vivo. J. Neurosci. 13, 5312-5323.
183. Metherate, R., Tremblay, N. and Dykes, R. W. (1988) Transient and prolonged effects of acetylcholine on responsiveness of cat somatosensory cortical neurons. J. Neurophysiol. 59, 1253-1276.
184. 3H]acetylcholine release from rat cortical synaptosomes. J. Neurosci. 10, 1185-1207.
185. Michel, R. N., Vu, C. Q., Tetzlaff, W. and Jasmin, B. J. (1994) Neural regulation of acetylcholinesterase mRNAs at mammalian neuromuscular synapses. J. Cell Biol. 127, 1061-1069.
186. Miledi, R., Molenaar, P. C. and Polak, R. L. (1984) Acetylcholinesterase activity in intact and homogenized skeletal muscle of the frog. J. Physiol., Lond. 349, 663-686.
187. Milusheva, E., Baranyi, M., Zelles, T., Mike, A. and Vizi, E. S. (1994) Release of acetylcholine and noradrenaline from the cholinergic and adrenergic afferents in rat hippocampal CA1. CA3 and dentate gurus regions. Eur. J. Neurosci. 6, 187-192.
188. Moruzzi, G. and Magoun, H. W. (1949) Brain stem reticular formation and activation of the EEG. Electroemephaiogr. Clin. Neurophysiol. 1, 455-473.
189. Mrzljak, L., Levey, A. I. and Goldman-Rakic, P. S. (1993) Association of m1 and m2 muscarinic receptor proteins with asymmetric synapses in the primate cerebral cortex: Morphological evidence for cholinergic modulation of excitatory neurotransmission. Proc, Natl. Acad. Sci. U.S.A. 90, 5194-5198.
190. Mrzljak, L., Pappy, M., Léránth, C. and Goldman-Rakic, P. S. (1995) Cholinergic synaplic circuitry in the macaque prefrontal cortex. J. Comp. Neurol. 357, 603-617.
191. Newton, P. and Justice, J. B. Jr (1995) Quantitative microdialysis of acetylcholine under basal conditions and during acetylcholinesterase inhibition in the rat. Soc. Neurosci. Abstr. 21, 67.
192. Nicholson, C. and Rice, M. E. (1991) Diffusion of ions and transmitters in the brain cell microenvironment. In: Volume Transmission in the Brain: Novel Mechanisms for Neural Transmission. pp. 279-294. Eds K. Fuxe and L. F. Agnati. Raven Press: New York.
193. Nilsson, O. G., Kalén, P., Rosengren, E. and Björklund, A. (1990) Acetylcholine release in the rat hippocampus as studied by microdialysis is dependent on axonal impulse flow and increases during behavioral activation. Neuroscience 36, 325-328.
194. Nitecka, L. and Frotscher, M. (1989a) Organization and synaptic interconnections of GABAergic and cholinergic elements in the rat amygdaloid nuclei: single-and double-immunolabeling studies. J. Camp. Neurol. 279, 470-490.
195. Nitecka, L. and Frotscher, M. (1989b) Cholinergic-GABAergic synaptic interconnections in the rat amygdaloid complex: an electron microscopic double immunostaining study. In: Experientia Supplementum Central Cholinergic Synaptic Transmission, Vol. 57, pp. 42-49. Eds M. Frotscher and U. Misgeld. Birkhaüser: Basel.
196. Ogston. A. G. (1955) Removal of acetylcholine from a limited volume by diffusion. J. Physiol., Lond. 128, 222-223.
197. Pape, H.-C. and Mager. R. (1992) Nitric oxide controls oscillatory activity in thalamocortical neurons. Neuron 9, 441-448.
198. Paré, D. and Steriade, M. (1990) Control of the mammillothalamic axis by brainstem cholinergic laterodorsal segmental afferents: possible involvement in mnemonic processes. In: Brain Cholinergic Systems, pp. 337-354. Eds M. Steriade and D. Biesold. Oxford University Press: Oxford and New York.
199. Paré, D., Steriade, M., Deschênes, M. and Bouhassira, D. (1990) Prolonged enhancement of anterior thalamic synaptic responsiveness by stimulation of a brainstem cholinergic group. J. Neurosci. 10, 20-33.
200. Parnavelas, J. G., Kelly, W.. Franke. E. and Eckenstein, F. (1986) Cholinergic neurons and fibres in the rat visual cortex. J. Neurocytol. 15, 329-336.
201. Phelps, P. E., Houser, C. R. and Vaughn, J. E. (1985) Immunocytochemical localization of choline acetyltransferase within the rat neostriatum: a correlated light and electron microscopic study of cholinergic neurons and synapses. J. Comp. Neurol. 238, 286-307.
202. Pickel, V. M. and Chan, J. (1990) Spiny neurons lacking choline acetyltransferase immunoreactivity are major targets of cholinergic and catecholaminergic terminals in rat striatum. J. Neurosci. Res. 25, 263-280.
203. Potter, P. E. and Nitta, S. (1993) Alterations in modulation of acetylcholine release following lesion of hippocampal cholinergic neurons with the neurotoxin AF64A. Neuropharmacology 32, 519-526.
204. Quinn, D. M. (1987) Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states. Chem. Rev. 87, 955-979.
205. Quirion, R., Richard, J. and Dam, T. V. (1985) Evidence for the existence of serotonin type-2 receptors on cholinergic terminals in rat cortex. Brain Res. 333, 345-349.
206. 2-like receptor subtype. Neuroscience 29, 271-289.
207. Quirion, R., Richard, J. and Wilson, A. (1994) Muscarinic and nicotinic modulation of cortical acetylcholine release monitored by in vivo microdialysis in freely moving rats. Synapse 17, 92-100.
208. Raczkowski. D. and Fitzpatrick. D. (1989) Organization of cholinergic synapses in the cat's dorsal lateral geniculate and perigeniculate nuclei. J. Comp. Neurol. 288, 676-690.
209. Raiteri, M., Leardi, R. and Marchi, M. (1984) Heterogeneity of presynaptic muscarinic receptors regulating neurotransmitter release in the rat brain. J. Pharmacol. Exp. Ther. 228, 209-214.
210. Rakonczay, Z. and Brimijoin, S. (1988) Biochemistry and pathophysiology of the molecular forms of cholinesterases. In: Subcellular Biochemistry, Vol. 12, pp. 336-378. Ed. J. R. Harris. Plenum Press: New York and London.
211. Rasmusson, D. D., Clow, K. and Szerb, J. C. (1994) Modification of neocortical acetylcholine release and electroencephalogram desynchronization due to brainstem stimulation by drugs applied to the basal forebrain. Neuroscienee 60, 665-677.
212. Rasmusson, D. D.. Szerb, J. C. and Jordan, J. L. (1996) Differential effects of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid and N-methyl-D-aspartate receptor antagonists applied to the basal forebrain on cortical acetylcholine release and EEC desynchronization. Neuroscience 72, 419-427.
213. Reader, T. A.. Ferron, A., Descarries, L. and Jasper, H. H. (1979) Modulatory role for biogenic amines in the cerebral cortex. Microiontophoretic studies. Brain Res. 160, 217-229.
214. Romero. E. and Smith, A. D. (1979) Release of acetylcholinesterase from superfused slices of rat hypothalamus. J. Physiol., Lond. 301, 52P.
215. Rosenberry, T. (1975) Acetylcholinesterase. Adv. Enzymol. 43, 103-218.
216. Rosenberry, T. (1979) Quantitative simulation of endplate currents at neuromuscular junctions based on the reaction of acetylcholine with acetylcholine receptor and acetylcholinesterase. Biophys. J. 26, 263-290.
217. Rotundo, R. L. and Carbonetto, S. T. (1987) Neurons segregate clusters of membrane-bound acetylcholinesterase along their neurites. Proc. Natl. Acad. Sci. U.S.A. 84, 2063-2067.
218. Rotundo, R. L. and Fambrough, D. M. (1980) Secretion of acetylcholinesterase: relation to acetylcholine receptor metabolism. Cell 22, 583-594.
219. Rovira, C., Ben-Ari, Y., Cherubini, E., Krnjevic, K. and Ropert, N. (1983) Pharmacology of the dendritic action of acetylcholine and further observations on the somatic disinhibition in the rat hippocampus in situ. Neuroscience 8, 97-106.
220. Salpeter, M. M. (1987) Vertebrate neuromuseular junctions: general morphology, molecular organisation, and functional consequences. In: The Vertebrate Neuromuscular Junction. pp. 1-54. Ed. M. M. Salpeter. Alan R. Liss: New York.
221. Salpeter, M. M. and Eldefrawi, M. (1973) Sizes of endplate compartments, densities of acetylcholine receptor and other quantitative aspects of neuromuscular transmission. J. Histochem. Cytochem. 21, 769-778.
222. Sargent, P. B. (1993) The diversity of neuronal nicotinic acetylcholine receptors. Annu. Rev. Neurosci. 16, 403-443.
223. Scanziani, M., Salin, P. A., Vogt, K. E., Malenka, R. C. and Nicoll, R. A. (1997) Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors. Nature 385, 630-634.
224. Scarsella. G., Toschi. G., Bareggi, S. R. and Giacobini, E. (1979) Molecular forms of cholinesterases in cerebrospinal fluid. blood plasma, and brain tissue of the beagle dog. J. Neurosci. Res. 4, 19-24.
225. Schmitt, F. O. (1984) Molecular regulators of brain function: a new view. Neuroscience 13, 991-1001.
226. Schröder, H., Zilles. K., Maelicke, A. and Hajós, F. (1989) Iminunohisto-and cytochemical localisation of cortical nicotinic cholinoceptors in rat and man. Brain Res. 502, 287-295.
227. Schumacher, M., Camp, S., Maulet, Y., Newton, M., MacPhee-Quigley, K., Taylor, S. S., Friedmann. T. and Taylor, P. (1986) Primary structure of acetylcholinesterase: implications for regulation and function. Fed. Proc. 45, 2976-2981.
228. Schwartz, M. L. and Mrzljak. L. (1993) Cholinergic innervation of the mediodorsal thalamic nucleus in the monkey: ultrastructural evidence supportive of functional diversity. J. Comp. Neurol. 327, 48-62.
229. Segal, M. (1983) Rat hippocampal neurons in culture: response to electrical and chemical stimuli. J. Neurophysiol. 50, 1249-1264
230. Sheridan, R. D. and Sutor, B. (1990) Presynaptic M1 muscarinic cholinoceptors mediate inhibition of excitatory synaptic transmission in the hippocampus in vitro. Neurosci. Lett. 108, 273-278.
231. Silver, A. (1974) The biology of cholinesterases In: Frontiers of Biology, Vol. 36. Eds A. Neuberger and E. L. Tatum. Elsevier: Amsterdam.
232. Singer, W. and Gray, C. M. (1995) Visual feature and the temporal correlation hypothesis. Annu. Rev. Neurosci. 18, 555-586.
233. Skau, K. A. and Brimijoin, S. (1978) Release of acetylcholinesterase from rat hemidiphragm preparations stimulated through the phrenic nerve. Nature 276, 224-226.
234. Small, D. H., Michaelson, S. and Sberna, G. (1996) Non-classical actions of cholinesterases: roles in cellular differentiation, tumorigenesis and Alzheimer's disease. Neurochem. Int. 28, 453-483.
235. Snyder, S. H. and Bredt, D. S. (1991) Nitric oxide as a neuronal messenger. Trends Pharmacol. Sci. 12, 125-128.
236. Soltesz, I., Lightowler, S., Leresche, N., Jassik-Gerschenfeld, D., Pollard, C. E. and Crunelli, V. (1991) Two inward currents and the transformation of low-frequency oscillations of rat and cat thalamocortical cells. J. Physiol., Lond. 441, 175-197.
237. Somogyi, P. and Chubb, I. W. (1976) The recovery of acetylcholinesterase activity in the superior cervical ganglion of the rat following its inhibition by diisopropylfluoridate: a biochemical and cytochemical study. Neuroscience 1, 413-421.
238. Starke, K., Göthert, M. and Kilbinger, H. (1989) Modulation of neurotransmitter release by presynaptic autoreceptors. Physiol. Rev. 69, 864-989.
239. Stephens, H. R. and Gisiger, V. (1984) Acetylcholinesterase localization in fast and slow muscles of normal and dystrophic mice. In: Cholinesterases: Fundamental and Applied Aspects, p. 90. Eds M. Brzin, E. A. Barnard and D. Sket. De Gruyter: Berlin.
240. Steriade, M. and Deschênes, M. (1984) The thalamus as a neuronal oscillator. Brain Res. Rev. 8, 1-63.
241. Steriade, M. and Deschênes, M. (1988) Intrathalamic and brainstem-thalamic networks involved in resting and alert states. In: Cellular Thalamic Mechanisms, pp. 51-76. Eds M. Bentivoglio and R. Spreafico. Elsevier: Amsterdam.
242. Steriade, M. and McCarley, R. W. (1990) Brainstem Control of Wakefulness and Sleep. Plenum Press: New York.
243. Steriade, M., Datta, S., Paré, D., Oakson, G. and Curró Dossi, R. (1990) Neuronal activities in brainstem cholinergic nuclei related to tonic activation processes in thalamocortical systems. J. Neurosci. 10, 2541-2559.
244. Steriade, M., Curró Dossi, R. and Nuǹez, A. (1991) Network modulation of a slow intrinsic oscillation of cat thalamocortical neurons implicated in sleep delta waves: cortically induced synchronisation and brainstem cholinergic suppression. J. Neurosci. 11, 3200-3217.
245. Steriade, M., Amzica, F. and Nunez, A. (1993a) Cholinergic and noradrenergic modulation of the slow (∼0.3 Hz) oscillation in neocortical cells. J. Neurophysiol. 70, 1384-1400.
246. Steriade, M., McCormick, D. A. and Sejnowski, T. J. (1993b) Thalamocortical oscillations in the sleeping and aroused brain. Science 262, 679-685.
247. Steriade, M., Amzica, F. and Contreras, D. (1996) Synchronization of fast (30-40 Hz) spontaneous cortical rhythms during brain activation. J. Neurosci. 16, 392-417.
248. Sugaya, K. and McKinney, M. (1994) Nitric oxide syntase gene expression in cholinergic neurons in the rat brain examined by combined immunocytochemistry and in situ hybridization histochemistry. Mol Brain Res. 23, 111-125.
249. Summers, K. L., Cuadra, G., Naritoku, D. and Giacobini, E. (1994) Effects of nicotine on levels of acetylcholine and biogenic amine in rat cortex. Drug Dev. Res. 31, 108-119.
250. Sveistrup, H., Chan, R. Y. Y. and Jasmin, B. J. (1995) Chronic enhancement of neuromuscular activity increases acetylcholinesterase gene expression in skeletal muscle. Am. J. Physiol. 269(Cell Physiol. 38), C856-C862.
251. 3H]-acetylcholine from rat hippocampal slice: effect of septal lesion and of graded concentrations of muscarinic agonists and antagonists. Brain Res. 128, 285-291.
252. Taber, M. T. and Fibiger, H. C. (1994) Cortical regulation of acetylcholine release in rat striatum. Brain Res. 639, 354-356.
253. Tao, L. and Nicholson, C. (1996) Diffusion of albumins in rat cortical slices and relevance to volume transmission. Neuroscience 75, 839-847.
254. Taylor, P., Maulet, Y. and Newton, M. (1986) A molecular perspective on the polymorphism of acetylcholinesterase. Trends Pharmacol. Sci. 7, 321-323.
255. Tennyson, V. M., Kremzner, L. T. and Brzin, M. (1977) Electron microscopic-cytochemical and biochemical studies of acetylcholinesterase activity in denervated muscle of rabbits. J. Neuropath. Exp. Neurol. 36, 245-275.
256. Testylier, G. and Dykes, R. W. (1996) Acetylcholine release from frontal cortex in the waking rat measured by microdialysis without acetylcholinesterase inhibitors: effects of diisopropylfluorophosphate. Brain Res. 740, 307-315.
257. Thorne, B. and Potter, P. E. (1995) Lesion with the neurotoxin AF64A alters hippocampal cholinergic receptor function. Brain Res. Bull. 38, 121-127.
258. Umbriaco, D., Watkins, K. C., Descarries, L., Cozzari, C. and Hartman, B. K. (1994) Ultrastructural and morphometric features of the acetylcholine innervation in adult rat parietal cortex. An electron microscopic study in serial sections. J. Comp. Neurol. 348, 351-373.
259. Umbriaco, D., Garcia, S., Beaulieu, C. and Descarries, L. (1995) Relational features of acetylcholine, noradrenaline, serotonin and GABA axon terminals in the stratum radiatum of adult rat hippocampus (CA1). Hippocampus 5, 605-620.
260. Valentino, R. J. and Dingledine, R. (1981) Presynaptic inhibitory effect of acetylcholine in the hippocampus. J. Neurosci. 1, 784-792.
261. van der Zee, E. A., Matsuyama, T., Strosberg, A. D., Traber, J. and Luiten, P. G. M. (1989) Demonstration of muscarinic acetylcholine receptor-like immunoreactivity in the rat forebrain and upper brainstem. Histochemistry 92, 475-485.
262. Vannucchi, M. G. and Pepeu, G. (1995) Muscarinic receptor modulation of acetylcholine release from rat cerebral cortex and hippocampus. Neurosci. Lett. 190, 53-56.
263. Vaucher, E. and Hamel, E. (1995) Cholinergic basal forebrain neurons project to cortical microvessels in the rat: electron microscopic study with anterogradely transported Phaseolus vulgaris leucoagglutinin and choline acetyltransferase immunocytochemistry. J. Neurosci. 15, 7427-7441.
264. Vidal, C. and Changeux, J.-P. (1993) Nicotinic anc muscarinic modulations of excitatory synaptic transmission in the rat prefrontal cortex in vitro. Neuroscience 56, 23-32.
265. Vigny, M., Bon, S., Massoulié. J. and Leterrier, F. (1978) Active-site catalytic efficiency of acetylcholinesterase molecular forms in Electrophorus, Torpedo, rat and chicken., Eur. J. Biochem. 85, 317-323.
266. Vigny, M., Bon, S., Massoulié, J. and Gisiger, V. (1979) The subunit structure of mammalian acetylcholinesterase: catalytic subunits, dissociating effect of proteolysis and disulfide reduction on the polymeric forms. J. Neurochem. 33, 559-565.
267. Vizi, E. S. (1984) Non-synaptic Interactions Between Neurons: Modulation of Neurochemical Transmission. John Wiley, Chichester.
268. Vizi, E. S. and Lábos, E. (1991) Non-synaptic interactions at presynaptic level. Prog. Neurobiol. 37, 145-163.
269. Vuillet, J., Dimova, R., Nieoullon, A. and Kerkerian-Le Goff, L. (1992) Ultrastructural relationships between choline acetyltransferase-and neuropeptide Y-containing neurons in the rat striatum. Neuroscience 46, 351-360.
270. Wahl, L. M., Pouzat, C. and Stratford, K. J. (1996) Monte Carlo simulation of fast excitatory synaptic transmission at a hippocampal synapse. J. Neurophysiol. 75, 597-608.
271. Wainer, B. H., Bolam, J. P., Freund, T. F., Henderson, Z., Totterdell, S. and Smith, A. D. (1984) Cholinergic synapses in the rat brain: a correlated light and electron microscopic immunohistochemical study employing a monoclonal antibody against choline acetyltransferase. Brain Res. 308, 69-76.
272. Wathey, J. C., Nass, M. N. and Lester, H. A. (1979) Numerical reconstruction of the quantal event at nicotinic synapses. Biophys. J. 27, 145-164.
273. Weiler, M. H. (1989) Muscarinic modulation of endogenous acetylcholine release in rat neostriatal slices. J. Pharmacol. Exp. Ther. 250, 617-623.
274. Weiner, B. H. and Mesulam, M.-M. (1990) Ascending Cholinergic pathways in the rat brain. In: Brain Cholinergic Systems, pp. 65-119. Eds M. Steriade and D. Biesold. Oxford University Press: Oxford and New York.
275. Wessler, I. (1992) Acetylcholine at motor nerves: storage, release, and presynaptic modulation by autoreceptors and adrenoreceptors. Int. Rev. Neurobiol. 34, 283-384.
276. Wightman. R. M. and Zimmerman, J. B. (1990) Control of dopamine extracellular concentration in rat striatum by impulse flow and uptake. Brain Res. Rev. 15, 135-144.
277. Wilkie, G. I., Hutson, P. H., Stephens, M. W., Whiting, P. and Wonnacott, S. (1993) Hippocampal nicotinic autoreceptors modulate acetylcholine release. Biochem. Soc. Trans. 21, 429-431.
278. Wilkie, G. I., Hutson, P. H., Sullivan, J. P. and Wonnacott, S. (1996) Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes. Neurochem. Res. 21, 1141-1148.
279. Williams, J. A., Comisarow, J., Day, J., Fibiger, H. C. and Reiner, P. B. (1994) State-dependent release of acetylcholine in rat thalamus measured by in vivo microdialysis. J. Neurosci. 14, 5236-5242.
280. Williams, J. A., Vincent, S. R. and Reiner, P. B. (1997) Nitric oxide production in rat thalamus changes with behavioral state, local depolarization. and brainstem stimulation. J. Neurosci. 17, 420-427.
281. Wonnacott, S. (1997) Presynaptic nicotinic receptors. Trends Neurosci. 20, 92-98.
282. Wonnacott, S., Irons, J., Rapier, C., Thorne, B. and Lunt, G. G. (1989) Presynaptic modulation of transmitter release by nicotinic receptors. Prog. Brain Res. 79, 157-163.
283. Wonnacott, S., Soliakov, L., Wilkie, G., Redfern, P. and Marshall, D. (1996) Presynaptic nicotinic acetylcholine receptors in the brain. Drug Dev. Res. 38, 149-159.
284. Woodward, D. J., Moiser, H. C., Waterhouse, B. D. and Hoffer, B. J. (1979) Modulatory actions of norepinephrine in the central nervous system. Fedn Proc. 38, 2109-2116.
285. Woody, C. D., Swartz, B. E. and Gruen, E. (1978) Effects of acetylcholine and cyclic GMP on input resistance of cortical neurons in awake cats. Brain Res. 158, 373-395.
286. Xu, M., Nakamura, Y., Yamamoto, T., Natori, K., Irie, T., Utsumi, H. and Kato, T. (1991) Determinations of basal acetylcholine release in vivo by rat brain dialysis with a U-shaped cannula: effect of SM-10888, a putative therapeutic drug for Alzheimer's disease. Neurosci. Lett. 123, 179-182.
287. Yu, Z. J. and Wecker, L. (1994) Chronic nicotine administration differentially affects neurotransmitter release from rat striatal slices. J. Neurochem. 63, 186-194.
288. 2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy. Neuroscience 65, 709-730.
289. Zoli, M. and Agnati, L. F. (1996) Wiring and volume transmission in the central nervous system: the concept of closed and open synapses. Prog. Neurobiol. 49, 363-390.