Gene targeting and the biology of learning and memory

Annual Review of Genetics

Volumn 31, Issue , 1997, Pages 527-46

  Silva, Alcino J ^a   Smith, Alan M ^a   Giese, Karl Peter ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

Hippocampus; Long term potentiation; Mutants; Short term plasticity; Synapses; Transgenics

Indexed keywords

COGNITION; GENE TARGETING; GENETIC ANALYSIS; HIPPOCAMPUS; HUMAN; LEARNING; LONG TERM MEMORY; MEMORY CONSOLIDATION; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; REVIEW; SHORT TERM MEMORY;

ANIMALS; FORECASTING; GENE TARGETING; HUMANS; LEARNING; MEMORY;

ANIMALIA; MAMMALIA;

EID: 0031466973     PISSN: 00664197     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.genet.31.1.527     Document Type: Review

References (20)

1. Abel T, Nguyen PV, Barad M, Deuel TAS, Kandel ER, Bourtchuladze R. 1997. Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampusbased long-term memory. Cell 88:615-26
2. Alberini CM, Ghirardi M, Metz R, Kandel ER. 1994.C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia. Cell 76:1099-114
3. Amaral DG. 1993. Emerging principles of intrinsic hippocampal organization. Curr. Biol. 3:225-29
4. Amaral DG, Witter MR 1989. The threedimensional organization of the hippocampal formation: a review of anatomical data. Neuroscience 31:571-91
5. Bach ME, Hawkins RD, Osman M, Kandel ER, Mayford M. 1995. Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency. Cell 81:905-15
6. Bannerman DM, Good MA, Butcher SP, Ramsay M, Morris RG. 1995. Distinct components of spatial learning revealed by prior training and NMDA receptor blockade. Nature 378:182-86
7. Barlow J. 1993. The Electroencephalogram: Its Patterns and Origins. Cambridge, MA: MIT Press
8. Bartsch D, Ghirardi M, Skehel PA, Karl KA, Herder SP, Chen M, et al. 1995. Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change. Cell 83:979-92
9. +)- and stimulus durationdependent switch for hippocampal gene expression. Cell 87:1203-14
10. Bliss TVP, Collingridge GL. 1993. A synaptic model of memory: long-term-potentiation. Nature 361:31-39
11. Bolshakov VY, Siegelbaum SA. 1995. Regulation of hippocampal transmitter release during development and long-term potentiation. Science 269:1730-34
12. Bourtchuladze R, Frenguelli B, Blendy J, Cioffi D, Schutz G, Silva A. 1994. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element binding protein. Cell 79:59-68
13. Brandon EP, Zhuo M, Huang YY, Qi M, Gerhold KA, et al. 1995. Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 92:8851-55
14. Buonomano DV, Merzenick MM. 1995. Tranformation of temporal information into a spatial code by a neural network based on realistic neuronal properties. Science 267:1028-31
15. +/calmodulin-dependent protein kinase in developing rat brain. J. Neurosci. 10:1788-98
16. Cain D. 1997. LTP, NMDA, genes and learning. Curr. Opin. Neurobiol. 7:235-42
17. Chapman PF, Frenguelli B, Smith A, Chen C-M, Silva AJ. 1995. The α-Calcium-Calmodulin Kinase II: a bi-directional modulator of pre-synaptic plasticity. Neuron 14:591-97
18. Chen C, Rainnie DG, Greene RW, TonegawaS. 1994. Abnormal fear response and agressive behavior in mutant mice deficient for α-calcium calmodulin kinase II. Science 266:291-94
19. Dash PK, Hochner B, Kandel ER. 1990. Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation. Nature 345:718-21
20. Davis HP, Squire LR. 1984. Protein synthesis and memory. Psychol. Bull. 96:518-59