Effectiveness of food fortification in improving nutritional status of mothers and children in Indonesia

International Journal of Environmental Research and Public Health

Volumn 18, Issue 4, 2021, Pages 1-12

  Dewi, Nikmah Utami ^a   Mahmudiono, Trias ^b  

^a University of Tadulako   (Indonesia)

^b AIRLANGGA UNIVERSITY   (Indonesia)

Author keywords

Fortification; Indonesia; Nutritional status; Stunting

Indexed keywords

ALBUMIN; FERRITIN; FOLIC ACID; HEMOGLOBIN; IODINE; IRON; RETINOL; RIBOFLAVIN; THIAMINE; TRACE ELEMENT; ZINC;

CHILD HEALTH; DIET; GROWTH; MATERNAL HEALTH; NUTRITIONAL STATUS; VITAMIN DEFICIENCY;

ALBUMIN BLOOD LEVEL; ANEMIA; ARTICLE; BIRTH WEIGHT; BODY HEIGHT; BREAST FEEDING; CELL DIFFERENTIATION; CELL FUNCTION; CHILD NUTRITION; CLINICAL EFFECTIVENESS; FERRITIN BLOOD LEVEL; FOOD FORTIFICATION; FOOD PROCESSING; FORTIFIED FOOD; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HOMEOSTASIS; HUMAN; INCIDENCE; INDONESIA; IRON DEFICIENCY; MALNUTRITION; MATERNAL NUTRITION; NUTRITIONAL STATUS; OSTEOBLAST; OSTEOCLAST; PREMATURE LABOR; PREVALENCE; RETINOL DEFICIENCY; RISK REDUCTION; STUNTING; SYSTEMATIC REVIEW; TREATMENT DURATION; VITAMIN BLOOD LEVEL; WHEAT FLOUR; CHILD; EPIDEMIOLOGY; FEMALE; MOTHER;

INDONESIA;

CHILD; FEMALE; FOOD, FORTIFIED; HUMANS; INDONESIA; MICRONUTRIENTS; MOTHERS; NUTRITIONAL STATUS;

EID: 85101583942     PISSN: 16617827     EISSN: 16604601     Source Type: Journal    
DOI: 10.3390/ijerph18042133     Document Type: Article

References (64)

1. Ruel-Bergeron, J.C.; Stevens, G.A.; Sugimoto, J.D.; Roos, F.F.; Ezzati, M.; Black, R.E.; Kraemer, K. Global Update and Trends of Hidden Hunger, 1995-2011: The Hidden Hunger Index. PLoS ONE 2015, 10, e0143497.
2. Balitbangkes. Riset Kesehatan Dasar; Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan Republik Indonesia:Jakarta, Indonesia, 2018.
3. Balitbangkes. Riset Kesehatan Dasar; Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan Republik Indonesia:Jakarta, Indonesia, 2013.
4. Desmansyah, D.; Purnamasari, R.; Theodorus, T.; Waiman, S. Correlation between vivax malaria infection and iron deficiency in children. Paediatr. Indones. 2011, 51, 207-212.
5. Zahrulianingdyah, A. The contribution of Indonesian women’s eating habit to iron deficiency anemia. Pakistan J. Nutr. 2016, 15, 1003-1007.
6. Nurdia, D.S.; Sumarni, S.; Suyoko; Hakim, M.;Winkvist, A. Impact of intestinal helminth infection on anemia and iron status during pregnancy: A community based study in Indonesia. S. Asian J. Trop. Med. Public Health 2001, 32, 14-22.
7. Andriastuti, M.; Ilmana, G.; Nawangwulan, S.A.; Kosasih, K.A. Prevalence of anemia and iron profile among children and adolescent with low socio-economic status. Int. J. Pediatr. Adolesc. Med. 2019.
8. Bening, S.; Margawati, A.; Rosidi, A. Zinc deficiency as risk factor for stunting among children aged 2-5 years. Universa Med. 2017, 36, 11-18.
9. Abdelhaleim, A.F.; Abdo Soliman, J.S.; Amer, A.Y.; Abdo Soliman, J.S. Association of Zinc Deficiency with Iron Deficiency Anemia and its Symptoms: Results from a Case-control Study. Cureus 2019, 11, e3811.
10. WHO. WHO Nutrition Landacape Information System (NLIS) Country Profile Indicators, Interpretation Guide; WHO: Geneva, Switzerland, 2010.
11. Kementerian PPN/Bapennas. Rencana Pembangunan Jangka Menengah Nasional 2020-2024; Kementerian PPN/Bapennas: Jakarta, Indonesia, 2019.
12. Arnold, T. Chapter 5.4 Nutrition-Specific and Nutrition-Sensitive Interventions. In Good Nutrition: Perspectives for the 21st Century; Karger: Basel, 2016; pp. 276-288.
13. WHO. WHO and FAO Guidelines on Food Fortification with Micronutrients; WHO: Geneva, Switzerland, 2006.
14. Pilz, S.; März, W.; Cashman, K.D.; Kiely, M.E.; Whiting, S.J.; Holick, M.F.; Grant, W.B.; Pludowski, P.; Hiligsmann, M.; Trummer, C.; et al. Rationale and Plan for Vitamin D Food Fortification: A Review and Guidance Paper. Front. Endocrinol. (Lausanne) 2018, 9, 373.
15. Haas, J.D.; Luna, S.V.; Lung’aho, M.G.; Wenger, M.J.; Murray-Kolb, L.E.; Beebe, S.; Gahutu, J.-B.; Egli, I.M. Consuming Iron Biofortified Beans Increases Iron Status in RwandanWomen after 128 Days in a Randomized Controlled Feeding Trial. J. Nutr. 2016, 146, 1586-1592.
16. Finkelstein, J.L.; Fothergill, A.; Hackl, L.S.; Haas, J.D.; Mehta, S. Iron biofortification interventions to improve iron status and functional outcomes. Proc. Nutr. Soc. 2019, 78, 197-207.
17. Menteri Perindustrian. Peraturan Menteri Perindustrian Republik Indonesia Nomor 47 tahun 2018 tentang Perubahan Ketiga atas Peraturan Menteri Perindustrian Nomor 87/M-IND/PER/12/2013 tentang Pemberlakuan SNI Minyak Goreng Sawit Secara Wajib; Menteri Perindustrian Republik Indonesia: Jakarta, Indonesia, 2018.
18. Minister of Industry. Minister of Industry and Trade Regulation Number 153/MPP/Kep/5/2001; Minister of Industry and Trade Republic of Indonesia: Jakarta, Indonesia, 2001.
19. Presiden Republik Indonesia. Keputusan Presiden Republik Indonesia Nomor 69 Tahun 1994 tentang Pengadaan Garam Beriodium; Presiden Republik Indonesia: Jakarta, Indonesia, 1994.
20. Sadighi, J.; Nedjat, S.; Rostami, R. Systematic review and meta-analysis of the effect of iron-fortified flour on iron status of populations worldwide. Public Health Nutr. 2019, 22, 3465-3484.
21. Athe, R.; Dwivedi, R.; Pati, S.; Mazumder, A.; Banset, U. Meta-analysis approach on iron fortification and its effect on pregnancy and its outcome through randomized, controlled trials. J. Fam. Med. Prim. Care 2020, 9, 513.
22. Tam, E.; Keats, E.C.; Rind, F.; Das, J.K.; Bhutta, Z.A. Micronutrient Supplementation and Fortification Interventions on Health and Development Outcomes among Children Under-Five in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis. Nutrients 2020, 12, 289.
23. Pineda, O. Fortification of sugar with vitamin A. Food Nutr. Bull. 1998, 19, 131-136.
24. Favaro, R.M.D.; Miyasaaka, C.K.; Desai, I.D.; Dutra de Oliveira, J.E. Evaluation of the effect of heat treatment on the biological value of vitamin A fortified soybean oil. Nutr. Res. 1992, 12, 1357-1363.
25. Mendu, V.V.R.; Nair, K.P.M.; Athe, R. Systematic review and meta-analysis approach on vitamin A fortified foods and its effect on retinol concentration in under 10 year children. Clin. Nutr. ESPEN 2019, 30, 126-130.
26. Hombali, A.S.; Solon, J.A.; Venkatesh, B.T.; Nair, N.S.; Peña-Rosas, J.P. Fortification of staple foods with vitamin A for vitamin A deficiency. Cochrane Database Syst. Rev. 2019.
27. Santos, J.A.R.; Christoforou, A.; Trieu, K.; McKenzie, B.L.; Downs, S.; Billot, L.;Webster, J.; Li, M. Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders. Cochrane Database Syst. Rev. 2019, 2019.
28. Aburto, N.J.; Abudou, M.; Candeias, V.; Tiaxiang Wu, P. Effect and safety of salt iodization to prevent iodine deficiency disorders:A systematic review with meta-analyses WHO Library Cataloguing-in-Publication Data. In WHO eLibrary of Evidence for Nutrition Actions (eLENA); WHO: Geneva, Switzerland, 2014; pp. 91-93.
29. Dijkhuizen, M.A.; Wieringa, F.T.; Soekarjo, D.; Van, K.T.; Laillou, A. Legal Framework for Food Fortification: Examples from Vietnam and Indonesia. Food Nutr. Bull. 2013, 34, S112-S123.
30. Sari, M.; Bloem, M.W.; de Pee, S.; Schultink, W.J.; Sastroamidjojo, S. Effect of iron-fortified candies on the iron status of children aged 4-6 y in East Jakarta, Indonesia. Am. J. Clin. Nutr. 2001, 73, 1034-1039.
31. Diana, A.; Mallard, S.R.; Haszard, J.J.; Purnamasari, D.M.; Nurulazmi, I.; Herliani, P.D.; Nugraha, G.I.; Gibson, R.S.; Houghton, L. Consumption of fortified infant foods reduces dietary diversity but has a positive effect on subsequent growth in infants from Sumedang district, Indonesia. PLoS ONE 2017, 12, e0175952.
32. Achadi, E.; Arifah, S.; Muslimatun, S.; Anggondowati, T.; Setiarini, A. Efektivitas Program Fortifikasi Minyak Goreng dengan Vitamin A terhadap Status Gizi Anak Sekolah di Kota Makasar. Kesmas Natl. Public Health J. 2010, 4, 255.
33. Sandjaja; Jusat, I.; Jahari, A.B.; Ifrad; Htet, M.K.; Tilden, R.L.; Soekarjo, D.; Utomo, B.; Moench-Pfanner, R.; Soekirman; et al. Vitamin A-fortified cooking oil reduces Vitamin A deficiency in infants, young children and women: Results from a programme evaluation in Indonesia. Public Health Nutr. 2015, 18, 2511-2522.
34. Sudikno, S.; Jus, I. The Impact of Vitamin A Fortified Vegetable Oil on Vitamin A Status of Children Under Five Years of Age: A Cohort Study. Health Sci. J. Indones. 2017, 8, 102-110.
35. Kasmawati. Pengaruh Pemberian Telur Beriodium terhadap Ekskresi Iodium Urin Penderita Defisiensi Yodium pada Anak Sekolah Dasar Kecamatan Pondidaha Kabupaten Konawe; Universitas Hasanuddin: Makassar, Indonesia, 2015.
36. Samsudin, M.; Nurcahyani, Y.D.; Ihsan, N.; Litbang, B.; Magelang, G.; Jayan, K. Dampak Intervensi Garam Beriodium Berbagai Dosis Terhadap Status Iodium Dan Fungsi Tiroid Normal Pada Anak Sekolah Dasar. Media Gizi Mikro Indones. 2016, 8, 1-16.
37. Samsudin, M.; Kusumawardani, H.; Prihatmi, E. Pengaruh penggunaan garam beriodium standar terhadap status iodium tinggi di daerah non endemik. Media Gizi Mikro Indones. 2015, 7, 57-66.
38. Widayani, S. Efikasi Dan Preferensi Biskuit Yang Difortifikasi Vitamin A Dan Zat Besi (Fe) Dan Kaitannya Dengan Konsumsi, Status Gizi dan Respon Imun Anak Balita; IPB University: Bogor, Indonesia, 2007.
39. Prihananto, V. Pengaruh Pemberian Pangan Yang Difortifikasi Zat Multi Gizi Mikro Terhadap Status Gizi Ibu Hamil Dan Berat Bayi Lahir; Dissertation; IPB University: Bogor, Indonesia, 2007.
40. Saragih, B.; Syarief, H.; Riyadi, H.; Nasoetion, A. Pengaruh Pemberian Pangan Fortifikasi Zat Multi Gizi Mikro Pada Ibu Hamil Terhadap Pertumbuhan Linier, Tinggi Lutut Dan Status Anemia Bayi. Gizi Indones. 2007, 30.
41. Saragih, B.; Syarief, H.; Riyadi, H.; Nasoetion, A. Pangan yang difortifikasi zat gizi mikro pada ibu hamil meningkatkan perkembangan motorik bayi. J. Gizi Klin. Indones. 2012, 9, 16.
42. Toronju, S.A.; Syam, A.; Palutturi, S.; Arif, M. Study of Hemoglobin and Ferritin Profile as Indicators in Children Hematology of 12-15 Years Provided Local Rice Fortification. Int. J. Sci. Basic Appl. Res. 2017, 32, 352-364.
43. Kurnia, P.; Rahmawaty, S. Efek Fortifikasi Fe dan Zn pada biskuit yang diolah dari kombinasi Tempe dan Bekatul untuk meningkatkan kadar Albumin Anak Balita Kurang Gizi dan Anemia. Eksplanasi 2010, 5, 1-14.
44. Semba, R.D.; Moench-Pfanner, R.; Sun, K.; De Pee, S.; Akhter, N.; Rah, J.H.; Campbell, A.A.; Badham, J.; Bloem, M.W.; Kraemer, K. Consumption of micronutrient-fortified milk and noodles is associated with lower risk of stunting in preschool-aged children in Indonesia. Food Nutr. Bull. 2011, 32, 347-353.
45. BPS-Statistics Indonesia. Statistical Yearbook of Indonesia; BPS-Statistics Indonesia: Jakarta, Indonesia, 2019.
46. Gera, T.; Sachdev, H.S.; Boy, E. Effect of iron-fortified foods on hematologic and biological outcomes: Systematic review of randomized controlled trials. Am. J. Clin. Nutr. 2012, 96, 309-324.
47. Minister of Health. Minister of Health Regulation No. 1452/MENKES/SK/X/2003; Minister of Health: Jakarta, Indonesia, 2003.
48. Zofkova, I.; Davis, M.; Blahos, J. Trace elements have beneficial, as well as detrimental effects on bone homeostasis. Physiol. Res. 2017, 66, 391-402.
49. Toxqui, L.; Vaquero, M.P. Chronic iron deficiency as an emerging risk factor for osteoporosis: A hypothesis. Nutrients 2015, 7, 2324-2344.
50. Balogh, E.; Paragh, G.; Jeney, V. Influence of Iron on Bone Homeostasis. Pharmaceuticals 2018, 11, 107.
51. Owino, V.O.; Kasonka, L.M.; Sinkala, M.M.;Wells, J.K.; Eaton, S.; Darch, T.; Coward, A.; Tomkins, A.M.; Filteau, S.M. Fortified complementary foods with or without α-amylase treatment increase hemoglobin but do not reduce breast milk intake of 9-mo-old Zambian infants. Am. J. Clin. Nutr. 2007, 86, 1094-1103.
52. Ara, G.; Khanam, M.; Rahman, A.S.; Islam, Z.; Farhad, S.; Sanin, K.I.; Khan, S.S.; Rahman, M.M.; Majoor, H.; Ahmed, T. Effectiveness of micronutrient-fortified rice consumption on anaemia and zinc status among vulnerable women in Bangladesh. PLoS ONE 2019, 14, e0210501.
53. Angeles-agdeppa, I.; Capanzana, M.V.; Barba, C.V.C.; Florentino, R.F.; Takanashi, K. Efficacy of Iron-Fortified Rice in Reducing Anemia Among Schoolchildren in the Philippines. Int. J. Vitam. Nutr. Res. 2008, 78, 74-86.
54. Chen, J.; Zhao, X.; Zhang, X.; Yin, S.; Piao, J.; Huo, J.; Yu, B.; Qu, N.; Lu, Q.; Wang, S.; et al. Studies on the Effectiveness of Nafeedta-Fortified Soy Sauce in Controlling Iron Deficiency: A Population-Based Intervention Trial. Food Nutr. Bull. 2005, 26, 177-186.
55. Waller, A.W.; Andrade, J.E.; Mejia, L.A. Performance Factors Influencing Efficacy and Effectiveness of Iron Fortification Programs of Condiments for Improving Anemia Prevalence and Iron Status in Populations: A Systematic Review. Nutrients 2020, 12, 275.
56. Green, A.S.; Fascetti, A.J. Meeting the Vitamin A Requirement: The Efficacy and Importance of β-Carotene in Animal Species. Sci. World J. 2016, 2016, 7393620.
57. Zhang, X.; Chen, K.; Qu, P.; Liu, Y.-X.; Li, T.-Y. Effect of biscuits fortified with different doses of vitamin A on indices of vitamin A status, haemoglobin and physical growth levels of pre-school children in Chongqing. Public Health Nutr. 2010, 13, 1462-1471.
58. Allen, L.H. Anemia and iron deficiency: Effects on pregnancy outcome. Am. J. Clin. Nutr. 2000, 71, 1280S-1284S.
59. Yang, Z.; Huffman, S.L. Review of fortified food and beverage products for pregnant and lactating women and their impact on nutritional status. Matern. Child Nutr. 2011, 7, 19-43.
60. Darnton-Hill, I.; Mkparu, U.C. Micronutrients in Pregnancy in Low- and Middle-Income Countries. Nutrients 2015, 7, 1744-1768.
61. Branca, F.; Ferrari, M. Impact of Micronutrient Deficiencies on Growth: The Stunting Syndrome. Ann. Nutr. Metab. 2002, 46 (Suppl. 1), 8-17.
62. Habicht, J.-P.; Martorell, R.; Rivera, J.A. Nutritional Impact of Supplementation in the INCAP Longitudinal Study: Analytic Strategies and Inferences. J. Nutr. 1995, 125, 1042S-1050S.
63. Okeyo, D.O. Impact of Food Fortification on Child Growth and Development during Complementary Feeding. Ann. Nutr. Metab. 2018, 73, 7-13.
64. Das, J.K.; Salam, R.A.; Kumar, R.; Bhutta, Z.A. Micronutrient fortification of food and its impact on woman and child health: A systematic review. Syst. Rev. 2013, 2, 67.