Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology

Cellular and Molecular Gastroenterology and Hepatology

Volumn 9, Issue 3, 2020, Pages 507-526

  Sontheimer Phelps, Alexandra ^a,d   Chou, David B ^a,e   Tovaglieri, Alessio ^a,f   Ferrante, Thomas C ^a   Duckworth, Taylor ^a,g   Fadel, Cicely ^a,h   Frismantas, Viktoras ^a   Sutherland, Arlene D ^a   Jalili Firoozinezhad, Sasan ^a,i   Kasendra, Magdalena ^a   Stas, Eric ^h   Weaver, James C ^a   Richmond, Camilla A ^b,h   Levy, Oren ^a   Prantil Baun, Rachelle ^a   Breault, David T ^b,h   Ingber, Donald E ^a,c,h  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

^c HARVARD UNIVERSITY   (United States)

^d UNIVERSITY OF FREIBURG   (Germany)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f ETH ZURICH   (Switzerland)

^g Northeastern University   (United States)

^h BOSTON CHILDREN S HOSPITAL   (United States)

ⁱ INSTITUTO SUPERIOR TÉCNICO   (Portugal)

Author keywords

Goblet Cell; Inflammatory Bowel Disease; Intestine; Microfluidic; Organ Chip; Organoid

Indexed keywords

F ACTIN; FC RECEPTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; KALLIKREIN; KRUPPEL LIKE FACTOR 4; MEPRIN; MUCIN 2; PROSTAGLANDIN E2; RESISTIN; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1; TRANSCRIPTION FACTOR ETS; TREFOIL FACTOR 3; UVOMORULIN; VOLTAGE GATED POTASSIUM CHANNEL; SLC12A1 PROTEIN, HUMAN; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 2;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL EXPANSION; CELL PROLIFERATION; COLON; COLON EPITHELIUM; COLONOID; GOBLET CELL; HUMAN; HUMAN CELL; HYDRATION; IN VITRO STUDY; INFLAMMATION; INTESTINE EPITHELIUM CELL; INTESTINE FUNCTION; MICROFLUIDICS; MUCUS; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; INTESTINE MUCOSA; LAB ON A CHIP; METABOLISM; ORGANOID; PHYSIOLOGY; PRIMARY CELL CULTURE; PROCEDURES;

CELLS, CULTURED; COLON; DINOPROSTONE; GOBLET CELLS; HUMANS; INTESTINAL MUCOSA; LAB-ON-A-CHIP DEVICES; MUCUS; ORGANOIDS; PRIMARY CELL CULTURE; SOLUTE CARRIER FAMILY 12, MEMBER 1;

EID: 85079665015     PISSN: None     EISSN: 2352345X     Source Type: Journal    
DOI: 10.1016/j.jcmgh.2019.11.008     Document Type: Article

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