Secretagogue response of goblet cells and columnar cells in human colonic crypts

American Journal of Physiology

Volumn 278, Issue 1 PART 1, 2000, Pages

  Halm, Dan R ^a   Halm, Susan Troutman ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

Author keywords

Adenosine; Cholinergic; Histamine; Inflammatory bowel disease; Prostaglandin E2

Indexed keywords

ADENOSINE; CARBACHOL; CHOLECYSTOKININ; CHOLINERGIC RECEPTOR STIMULATING AGENT; HISTAMINE; PROSTAGLANDIN E2;

ARTICLE; BODY FLUID; CELL GRANULE; CELL SIZE; CLASSIFICATION; COLON; CYTOLOGY; DRUG EFFECT; ENTERITIS; GOBLET CELL; HUMAN; INTESTINE MUCOSA; MATHEMATICS; METABOLISM; METHODOLOGY; MICROTOMY; MUCUS; PATHOLOGY; PHASE CONTRAST MICROSCOPY; SECRETION; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSINE; BIOLOGICAL TRANSPORT; BODY FLUIDS; CARBACHOL; CELL SIZE; CHOLECYSTOKININ; CHOLINERGIC AGONISTS; COLON; CYTOPLASMIC GRANULES; DINOPROSTONE; GOBLET CELLS; HISTAMINE; HUMANS; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; MATHEMATICS; MICROSCOPY, INTERFERENCE; MICROTOMY; MUCUS;

EID: 0033629691     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Augeron, C., T. Viosin, J. Maoret, B. Berthon, M. Laburthe, and C. L. Laboisse. Neurotensin and neuromedin N stimulate mucin output from human goblet cells (CL. 16E) via neurotensin receptors. Am. J. Physiol. 262 (Gastrointest. Liver Physiol. 25): G470-G476, 1992.
2. Carlstedt, I., A. Herrmann, H. Hovenberg, G. Lindell, H. Nordman, C. Wickstrom, and J. R. Davies. Soluble and insoluble mucins: identification of specific populations. Biochem. Soc. Trans. 23: 845-851, 1995.
3. Chang, W. W. L., and C. P. Leblond. Renewal of the epithelium in the descending colon of the mouse. I. Presence of three cell populations: vacuolated-columnar, mucous and argentaffin. Am. J. Anat. 131: 73-99, 1971.
4. Davis, C. W., M. L. Dowell, M. I. Lethem, and M. Van Scott. Goblet cell degranulation in isolated canine tracheal epithelium: response to exogenous ATP, ADP, and adenosine. Am. J. Physiol. 262 (Cell Physiol. 31): C1313-C1323, 1992.
5. Dharmsathaphorn, K., J. A. McRoberts, K. G. Mandel, L. D. Tisdale, and H. Masui. A human colonic tumor cell line that maintains vectorial electrolyte transport. Am. J. Physiol. 246 (Gastrointest. Liver Physiol. 9): G204-G208, 1984.
6. DiBona, D. R., K. L. Kirk, and R. D. Johnson. Microscopic investigation of structure and function in living epithelial tissues. Federation Proc. 44: 2693-2703, 1985.
7. Diener, M. Segmental differences along the crypt axis in the response of cell volume to secretagogues or hypotonic medium in the rat colon. Pflügers Arch. 426: 462-464, 1994.
8. Forstner, J. F., and G. G. Forstner. Calcium binding to intestinal goblet cell mucin. Biochim. Biophys. Acta 386: 283-292, 1975.
9. Forstner, J. F., and G. G. Forstner. Gastrointestinal mucus. In: Physiology of the Gastrointestinal Tract, edited by L. R. Johnson. New York: Raven, 1994, p. 1255-1283.
10. Goralski, A., W. Sawicki, and O. Blaton. Nonrandom distribution of goblet cells around the circumference of colonic crypt. Cell. Tissue Res. 160: 551-556, 1975.
11. Greco, V., G. Lauro, A. Fabbrini, and A. Torsoli. Histochemistry of the colonic epithelial mucins in normal subjects and in patients with ulcerative colitis. Gut 8: 491-496, 1967.
12. Halm, D. R., and R. A. Frizzell. Intestinal chloride secretion. In: Textbook of Secretory Diarrhea, edited by E. Lebenthal and M. Duffey. New York: Raven, 1990, p. 47-58.
13. Halm, D. R., and R. A. Frizzell. Ion transport across the large intestine. In: Handbook of Physiology. The Gastrointestinal System. Intestinal Absorption and Secretion. Bethesda, MD: Am. Physiol. Soc., 1991, sect. 6, vol. IV, p. 257-274.
14. Halm, D. R., S. T. Halm, D. R. DiBona, R. A. Frizzell, and R. D. Johnson. Selective stimulation of epithelial cells in colonic crypts: relation to active chloride secretion. Am. J. Physiol. 269 (Cell Physiol. 38): C929-C942, 1995.
15. Halm, D. R., K. L. Kirk, and K. C. Sathiakumar. Stimulation of chloride permeability in colonic crypts of Lieberkühn measured with a fluorescent indicator. Am. J. Physiol. 265 (Gastrointest. Liver Physiol. 28): G423-G431, 1993.
16. Halm, D. R., and R. Rick. Secretion of potassium and chloride across colonic epithelium: cellular localization using electron microprobe analysis. Am. J. Physiol. 262 (Cell Physiol. 31): C1001-C1011, 1992.
17. Hawkey, C. J., and D. S. Rampton. Prostaglandins in the gastrointestinal mucosa: are they important in its function, disease or treatment? Gastroenterology 89: 1162-1188, 1985.
18. Inoué, S., and K. R. Spring. Video Microscopy: The Fundamentals. New York: Plenum, 1997.
19. Kaftan, S. M., and N. A. Wright. Studies on the mechanisms of mucous cell depletion in experimental colitis. J. Pathol. 159: 75-85, 1989.
20. Kamijo, A., S. Terakawa, and K. Hisamatsu. Neurotransmitter-induced exocytosis in goblet and acinar cells of rat nasal mucosa studied by video microscopy. Am. J. Physiol. 265 (Lung Cell. Mol. Physiol. 9): L200-L209, 1993.
21. Kaye, G. I., C. M. Fenoglio, R. R. Pascal, and N. Lane. Comparative electron microscopic features of normal, hyperplastic and adenomatous human colonic epithelium: variations in cellular structure relative to the process of epithelial differentiation. Gastroenterology 64: 926-945, 1973.
22. King, M. Viscoelastic properties of airway mucus. Federation Proc. 39: 3080-3085, 1980.
23. Kirk, K. L., D. R. DiBona, and J. A. Schafer. Morphologic response of the rabbit cortical collecting tubule to peritubular hypotonicity: quantitative examination with differential interference contrast microscopy. J. Membr. Biol. 79: 53-64, 1984.
24. Krasny, E. J., Jr., and R. A. Frizzell. Fluid secretion by isolated colonic crypts (Abstract). Federation Proc. 43: 1087, 1984.
25. Kreusel, K., M. Fromm, J. Schulzke, and U. Hegel. Chloride secretion in epithelial monolayers of mucus-forming human colon cells (HT29/B6). Am. J. Physiol. 261 (Cell Physiol. 30): C574-C582, 1991.
26. Lohrmann, E., and R. Greger. Isolated perfused rabbit colon crypts: stimulation of chloride secretion by forskolin. Pflügers Arch. 425: 373-380, 1993.
27. Lohrmann, E., and R. Greger. The effect of secretagogues on ion conductance of in vitro perfused, isolated rabbit colonic crypts. Pflügers Arch. 427: 494-502, 1995.
28. McCool, D. J., M. A. Marcon, J. F. Forstner, and G. G. Forstner. The T84 human colonic adenocarcinoma cell line produces mucin in culture and releases it in response to various secretagogues. Biochem. J. 267: 491-500, 1990.
29. McCormick, D. A., L. W. L. Horton, and A. S. Mee. Mucin depletion in inflammatory bowel disease. J. Clin. Pathol. 43: 143-146, 1990.
30. Madara, J. L., K. Podolsky, N. W. King, P. K. Sehgal, R. Moore, and H. S. Winter. Characterization of spontaneous colitis in cotton-top tamarins (Saguinus oedipus) and its response to sulfasalazine. Gastroenterology 88: 13-19, 1985.
31. Malatjalian, D. A. Pathology of inflammatory bowel disease in colorectal mucosal biopsies. Dig. Dis. Sci. 32: 5S-15S, 1987.
32. Marcon, M. A., D. McCool, J. Forstner, and G. Forstner. Inhibition of mucin secretion in a colonic adenocarcinoma cell line by DIDS and potassium channel blockers. Biochim. Biophys. Acta 1052: 17-23, 1990.
33. Merlin, D., C. Augeron, X. Tien, X. Guo, C. L. Laboisse, and U. Hopfer. ATP-stimulated electrolyte and mucin secretion in the human intestinal goblet cell line HT29.CL16E. J. Membr. Biol. 137: 137-149, 1994.
34. 2+ effect on reduced viscosities of mucus secretions from chicken trachea in vitro. Biochim. Biophys. Acta 883: 486-495, 1986.
35. Neutra, M. R., L. J. O'Malley, and R. D. Specian. Regulation of intestinal goblet cell secretion. II. A survey of potential secretagogues. Am. J. Physiol. 242 (Gastrointest. Liver Physiol. 5): G380-G387, 1982.
36. Pascal, R. R., G. I. Kaye, and N. Lane. Colonic pericryptal fibroblast sheath: replication, migration and cytodifferentiation of a mesenchymal cell system in adult tissue. Gastroenterology 54: 835-851, 1968.
37. Phillips, T. E. Both crypt and villus intestinal goblet cells secrete mucin in response to cholinergic stimulation. Am. J. Physiol. 262 (Gastrointest. Liver Physiol. 25): G327-G331, 1992.
38. 2 on proliferation of an intestinal goblet cell line and its synthesis and secretion of mucin glycoproteins. Prostaglandins Leukot. Essent. Fatty Acids 48: 423-428, 1993.
39. Phillips, T. E., and J. Wilson. Morphometric analysis of mucous granule depletion and replenishment in rat colon. Dig. Dis. Sci. 38: 2299-2304, 1993.
40. Pittman, F. E., and J. C. Pittman. An electron microscopic study of the epithelium of normal human sigmoid colonic mucosa. Gut 7: 644-661, 1966.
41. Podolsky, D. K. Inflammatory bowel disease. N. Engl. J. Med. 325: 928-937, 1991.
42. Quinton, P. M. Composition and control of secretions from tracheal bronchial submucosal glands. Nature 279: 551-552, 1979.
43. Radwan, K. A., M. G. Oliver, and R. D. Specian. Cytoarchitectural reorganization of rabbit colonic goblet cells during baseline secretion. Am. J. Anat. 189: 365-376, 1990.
44. Richman, P. I., R. Tilly, J. R. Jass, and W. F. Bodmer. Colonic pericrypt sheath cells: characterization of cell type with new monoclonal antibody. J. Clin. Pathol. 40: 593-600, 1987.
45. Schafer, J. A., S. L. Troutman, and T. E. Andreoli. Volume reabsorption, transepithelial potential differences, and ionic permeability properties in mammalian superficial proximal straight tubules. J. Gen. Physiol. 64: 582-607, 1974.
46. Segawa, A., S. Terakawa, S. Yamashina, and C. R. Hopkins. Exocytosis in living salivary glands: direct visualization by video-enhanced microscopy and confocal laser microscopy. Eur. J. Cell Biol. 54: 322-330, 1991.
47. Sellin, J. H., and R. DeSoignie. Ion transport in human colon in vitro. Gastroenterology 93: 441-448, 1987.
48. Shamsuddin, A. M., P. C. Phelps, and B. F. Trump. Human large intestinal epithelium: light microscopy, histochemistry and ultrastructure. Hum. Pathol. 13: 790-803, 1982.
49. Singh, S. K., H. J. Binder, W. F. Boron, and J. P. Geibel. Fluid absorption in isolated perfused colonic crypts. J. Clin. Invest. 96: 2373-2379, 1995.
50. Specian, R. D., and M. R. Neutra. Mechanism of rapid mucus secretion in goblet cells stimulated by acetylcholine. J. Cell Biol. 85: 626-640, 1980.
51. Specian, R. D., and M. G. Oliver. The functional biology of intestinal goblet cells. Am. J. Physiol. 260 (Cell Physiol. 29): C183-C193, 1991.
52. Terakawa, S., and Y. Suzuki. Exocytosis in colonic goblet cells visualized by video-enhanced light microscopy. Biochem. Biophys. Res. Commun. 176: 466-472, 1991.
53. Ueki, I., V. F. German, and J. A. Nadel. Micropipette measurement of airway submucosal gland secretion: autonomic effects. Annu. Rev. Respir. Dis. 121: 351-357, 1980.
54. Verdugo, P. Goblet cells: secretion and mucogenesis. Annu. Rev. Physiol. 52: 157-176, 1990.
55. Verdugo, P., I. Deyrup-Olsen, M. Aitken, M. Villalon, and D. Johnson. Molecular mechanism of mucin secretion. I. The role of intragranular charge shielding. J. Dent. Res. 66: 506-508, 1987.
56. Vogel, S. Life in Moving Fluids: The Physical Biology of Flow. Boston, MA: Willard Grant, 1981.
57. Warhurst, G., N. B. Higgs, A. Tonge, and L. A. Turnberg. Stimulatory and inhibitory actions of carbachol on chloride secretory responses in human colonic cell line T84. Am. J. Physiol. 261 (Gastrointest. Liver Physiol. 24): G220-G228, 1991.
58. Weibel, E. R. Stereological Methods. New York: Academic, 1979.
59. Woda, B. A., K. Forde, and N. Lane. A unicryptal colonic adenoma, the smallest colonic neoplasm yet observed in a non-polyposis individual. Am. J. Clin. Pathol. 68: 631-632, 1977.