-
1
-
-
84880154386
-
Unusual properties of the cytochrome P450 superfamily
-
Lamb, D. C. & Waterman, M. R. Unusual properties of the cytochrome P450 superfamily. Philos. Trans. R. Soc. Lond. B Biol. Sci. 368, 20120434, doi:10.1098/rstb.2012.0434 (2013).
-
(2013)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.368
, pp. 20120434
-
-
Lamb, D.C.1
Waterman, M.R.2
-
2
-
-
84962555267
-
Applications of microbial cytochrome P450 enzymes in biotechnology and synthetic biology
-
Girvan, H. M. & Munro, A. W. Applications of microbial cytochrome P450 enzymes in biotechnology and synthetic biology. Curr. Opin. Chem. Biol. 31, 136-145, doi:10.1016/j.cbpa.2016.02.018 (2016).
-
(2016)
Curr. Opin. Chem. Biol.
, vol.31
, pp. 136-145
-
-
Girvan, H.M.1
Munro, A.W.2
-
3
-
-
84855952259
-
P450(BM3) (CYP102A1): Connecting the dots
-
Whitehouse, C. J., Bell, S. G. & Wong, L. L. P450(BM3) (CYP102A1): connecting the dots. Chem. Soc. Rev. 41, 1218-1260, doi:10.1039/c1cs15192d (2012).
-
(2012)
Chem. Soc. Rev.
, vol.41
, pp. 1218-1260
-
-
Whitehouse, C.J.1
Bell, S.G.2
Wong, L.L.3
-
4
-
-
84868318849
-
Diversity of P450 enzymes in the biosynthesis of natural products
-
Podust, L. M. & Sherman, D. H. Diversity of P450 enzymes in the biosynthesis of natural products. Nat. Prod. Rep. 29, 1251-1266, doi:10.1039/c2np20020a (2012).
-
(2012)
Nat. Prod. Rep.
, vol.29
, pp. 1251-1266
-
-
Podust, L.M.1
Sherman, D.H.2
-
5
-
-
33744520321
-
Cytochromes P450 as versatile biocatalysts
-
Bernhardt, R. Cytochromes P450 as versatile biocatalysts. J. Biotechnol. 124, 128-145, doi:10.1016/j.jbiotec.2006.01.026 (2006).
-
(2006)
J. Biotechnol.
, vol.124
, pp. 128-145
-
-
Bernhardt, R.1
-
6
-
-
85015136158
-
Prospects for applying synthetic biology to toxicology: Future opportunities and current limitations for the repurposing of cytochrome P450 systems
-
Behrendorff, J. B. & Gillam, E. M. Prospects for Applying Synthetic Biology to Toxicology: Future Opportunities and Current Limitations for the Repurposing of Cytochrome P450 Systems. Chem. Res. Toxicol. 30, 453-468, doi:10.1021/acs.chemrestox.6b00396 (2017).
-
(2017)
Chem. Res. Toxicol.
, vol.30
, pp. 453-468
-
-
Behrendorff, J.B.1
Gillam, E.M.2
-
7
-
-
21844434930
-
Structure and chemistry of cytochrome P450
-
Denisov, I. G., Makris, T. M., Sligar, S. G. & Schlichting, I. Structure and chemistry of cytochrome P450. Chem. Rev. 105, 2253-2277 (2005).
-
(2005)
Chem. Rev.
, vol.105
, pp. 2253-2277
-
-
Denisov, I.G.1
Makris, T.M.2
Sligar, S.G.3
Schlichting, I.4
-
8
-
-
33846473252
-
Cytochrome P450 systems - biological variations of electron transport chains
-
Hannemann, F., Bichet, A., Ewen, K. M. & Bernhardt, R. Cytochrome P450 systems - biological variations of electron transport chains. Biochim. Biophys. Acta 1770, 330-344 (2007).
-
(2007)
Biochim. Biophys. Acta
, vol.1770
, pp. 330-344
-
-
Hannemann, F.1
Bichet, A.2
Ewen, K.M.3
Bernhardt, R.4
-
9
-
-
84930226479
-
Biological diversity of cytochrome P450 redox partner systems
-
McLean, K. J., Luciakova, D., Belcher, J., Tee, K. L. & Munro, A. W. Biological diversity of cytochrome P450 redox partner systems. Adv. Exp. Med. Biol. 851, 299-317, doi:10.1007/978-3-319-16009-2-11 (2015).
-
(2015)
Adv. Exp. Med. Biol.
, vol.851
, pp. 299-317
-
-
McLean, K.J.1
Luciakova, D.2
Belcher, J.3
Tee, K.L.4
Munro, A.W.5
-
10
-
-
84355163053
-
Cytochrome P450 monooxygenases: An update on perspectives for synthetic application
-
Urlacher, V. B. & Girhard, M. Cytochrome P450 monooxygenases: an update on perspectives for synthetic application. Trends Biotechnol. 30, 26-36, doi:10.1016/j.tibtech.2011.06.012 (2012).
-
(2012)
Trends Biotechnol.
, vol.30
, pp. 26-36
-
-
Urlacher, V.B.1
Girhard, M.2
-
11
-
-
58149472888
-
Assembly of non-natural electron transfer conduits in the cytochrome P450 system: A critical assessment and update of artificial redox constructs amenable to exploitation in biotechnological areas
-
Hlavica, P. Assembly of non-natural electron transfer conduits in the cytochrome P450 system: a critical assessment and update of artificial redox constructs amenable to exploitation in biotechnological areas. Biotechnol. Adv. 27, 103-121 (2009).
-
(2009)
Biotechnol. Adv.
, vol.27
, pp. 103-121
-
-
Hlavica, P.1
-
12
-
-
68349152437
-
Regioselective biooxidation of (+)-valencene by recombinant E. Coli expressing CYP109B1 from bacillus subtilis in a two-liquid-phase system
-
Girhard, M. et al. Regioselective biooxidation of (+)-valencene by recombinant E. coli expressing CYP109B1 from Bacillus subtilis in a two-liquid-phase system. Microb. Cell Fact. 8, 36 (2009).
-
(2009)
Microb. Cell Fact.
, vol.8
, pp. 36
-
-
Girhard, M.1
-
13
-
-
84971012987
-
Semi-rational engineering of cytochrome CYP153A from marinobacter aquaeolei for improved omega-hydroxylation activity towards oleic acid
-
Duan, Y. et al. Semi-rational engineering of cytochrome CYP153A from Marinobacter aquaeolei for improved omega-hydroxylation activity towards oleic acid. Appl. Microbiol. Biotechnol. doi:10.1007/s00253-016-7634-1 (2016).
-
(2016)
Appl. Microbiol. Biotechnol
-
-
Duan, Y.1
-
14
-
-
84861303750
-
Adrenodoxin-A versatile ferredoxin
-
Ewen, K. M., Ringle, M. & Bernhardt, R. Adrenodoxin-a versatile ferredoxin. IUBMB Life 64, 506-512, doi:10.1002/iub.1029 (2012).
-
(2012)
IUBMB Life
, vol.64
, pp. 506-512
-
-
Ewen, K.M.1
Ringle, M.2
Bernhardt, R.3
-
15
-
-
77956225590
-
Regioselective hydroxylation of norisoprenoids by CYP109D1 from sorangium cellulosum so ce56
-
Khatri, Y. et al. Regioselective hydroxylation of norisoprenoids by CYP109D1 from Sorangium cellulosum So ce56. Appl. Microbiol. Biotechnol. 88, 485-495, doi:10.1007/s00253-010-2756-3 (2010).
-
(2010)
Appl. Microbiol. Biotechnol.
, vol.88
, pp. 485-495
-
-
Khatri, Y.1
-
16
-
-
77953081396
-
Characterization of the versatile monooxygenase CYP109B1 from bacillus subtilis
-
Girhard, M., Klaus, T., Khatri, Y., Bernhardt, R. & Urlacher, V. B. Characterization of the versatile monooxygenase CYP109B1 from Bacillus subtilis. Appl. Microbiol. Biotechnol. 87, 595-607, doi:10.1007/s00253-010-2472-z (2010).
-
(2010)
Appl. Microbiol. Biotechnol.
, vol.87
, pp. 595-607
-
-
Girhard, M.1
Klaus, T.2
Khatri, Y.3
Bernhardt, R.4
Urlacher, V.B.5
-
17
-
-
84889571903
-
Cluster screening: An effective approach for probing the substrate space of uncharacterized cytochrome P450s
-
von Bühler, C., Le-Huu, P. & Urlacher, V. B. Cluster screening: an effective approach for probing the substrate space of uncharacterized cytochrome P450s. Chem Bio Chem 14, 2189-2198, doi:10.1002/cbic.201300271 (2013).
-
(2013)
Chem Bio Chem
, vol.14
, pp. 2189-2198
-
-
Von Bühler, C.1
Le-Huu, P.2
Urlacher, V.B.3
-
18
-
-
0343920070
-
Construction and characterization of a catalytic fusion protein system: P-450(11beta)-adrenodoxin reductase-adrenodoxin
-
doi: S0167-4838(99)00243-5
-
Cao, P. R., Bulow, H., Dumas, B. & Bernhardt, R. Construction and characterization of a catalytic fusion protein system: P-450(11beta)-adrenodoxin reductase-adrenodoxin. Biochim. Biophys. Acta 1476, 253-264, doi:S0167-4838(99)00243-5 (2000).
-
(2000)
Biochim. Biophys. Acta
, vol.1476
, pp. 253-264
-
-
Cao, P.R.1
Bulow, H.2
Dumas, B.3
Bernhardt, R.4
-
19
-
-
84937605477
-
Design and improvement of artificial redox modules by molecular fusion of flavodoxin and flavodoxin reductase from Escherichia coli
-
Bakkes, P. J. et al. Design and improvement of artificial redox modules by molecular fusion of flavodoxin and flavodoxin reductase from Escherichia coli. Sci. Rep. 5, 12158, doi:10.1038/srep12158 (2015).
-
(2015)
Sci. Rep.
, vol.5
, pp. 12158
-
-
Bakkes, P.J.1
-
20
-
-
84874048801
-
Chimeric P450 enzymes: Activity of artificial redox fusions driven by different reductases for biotechnological applications
-
Sadeghi, S. J. & Gilardi, G. Chimeric P450 enzymes: activity of artificial redox fusions driven by different reductases for biotechnological applications. Biotechnol. Appl. Biochem. 60, 102-110 (2013).
-
(2013)
Biotechnol. Appl. Biochem.
, vol.60
, pp. 102-110
-
-
Sadeghi, S.J.1
Gilardi, G.2
-
21
-
-
35348837263
-
Intramolecular electron transfer in a cytochrome P450cam system with a site-specific branched structure
-
Hirakawa, H., Kamiya, N., Tanaka, T. & Nagamune, T. Intramolecular electron transfer in a cytochrome P450cam system with a site-specific branched structure. Protein Eng. Des. Sel. 20, 453-459 (2007).
-
(2007)
Protein Eng. Des. Sel.
, vol.20
, pp. 453-459
-
-
Hirakawa, H.1
Kamiya, N.2
Tanaka, T.3
Nagamune, T.4
-
22
-
-
0034564517
-
Engineering artificial redox chains by molecular 'Lego'
-
135-153(discussion)
-
Sadeghi, S. J., Meharenna, Y. T., Fantuzzi, A., Valetti, F. & Gilardi, G. Engineering artificial redox chains by molecular 'Lego'. Faraday Discuss. 135-153(discussion), 171-190 (2000).
-
(2000)
Faraday Discuss
, pp. 171-190
-
-
Sadeghi, S.J.1
Meharenna, Y.T.2
Fantuzzi, A.3
Valetti, F.4
Gilardi, G.5
-
23
-
-
35848952082
-
Engineering and analysis of a self-sufficient biosynthetic cytochrome P450 PikC fused to the RhFRED reductase domain
-
Li, S., Podust, L. M. & Sherman, D. H. Engineering and analysis of a self-sufficient biosynthetic cytochrome P450 PikC fused to the RhFRED reductase domain. J. Am. Chem. Soc. 129, 12940-12941, doi:10.1021/ja075842d (2007).
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 12940-12941
-
-
Li, S.1
Podust, L.M.2
Sherman, D.H.3
-
24
-
-
73249150128
-
Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase
-
Li, S. et al. Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase. Proc. Natl. Acad. Sci. USA. 106, 18463-18468, doi:10.1073/pnas.0907203106 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 18463-18468
-
-
Li, S.1
-
25
-
-
0025344142
-
Genetically engineered P450 monooxygenases: Construction of bovine P450c17/yeast reductase fused enzymes
-
Shibata, M., Sakaki, T., Yabusaki, Y., Murakami, H. & Ohkawa, H. Genetically engineered P450 monooxygenases: construction of bovine P450c17/yeast reductase fused enzymes. DNA Cell Biol. 9, 27-36 (1990).
-
(1990)
DNA Cell Biol.
, vol.9
, pp. 27-36
-
-
Shibata, M.1
Sakaki, T.2
Yabusaki, Y.3
Murakami, H.4
Ohkawa, H.5
-
26
-
-
37349117637
-
Cytochrome P450/redox partner fusion enzymes: Biotechnological and toxicological prospects
-
McLean, K. J., Girvan, H. M. & Munro, A. W. Cytochrome P450/redox partner fusion enzymes: biotechnological and toxicological prospects. Expert Opin. Drug Metab. Toxicol. 3, 847-863, doi:10.1517/17425255.3.6.847 (2007).
-
(2007)
Expert Opin. Drug Metab. Toxicol.
, vol.3
, pp. 847-863
-
-
McLean, K.J.1
Girvan, H.M.2
Munro, A.W.3
-
27
-
-
4744337841
-
Expression and characterization of the two flavodoxin proteins of bacillus subtilis, YkuN and YkuP: Biophysical properties and interactions with cytochrome P450 BioI
-
Lawson, R. J., von Wachenfeldt, C., Haq, I., Perkins, J. & Munro, A. W. Expression and characterization of the two flavodoxin proteins of Bacillus subtilis, YkuN and YkuP: biophysical properties and interactions with cytochrome P450 BioI. Biochemistry 43, 12390-12409 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 12390-12409
-
-
Lawson, R.J.1
Von Wachenfeldt, C.2
Haq, I.3
Perkins, J.4
Munro, A.W.5
-
28
-
-
0347988149
-
Steady-state kinetic investigation of cytochrome P450cam: Interaction with redox partners and reaction with molecular oxygen
-
Purdy, M. M., Koo, L. S., Ortiz de Montellano, P. R. & Klinman, J. P. Steady-state kinetic investigation of cytochrome P450cam: interaction with redox partners and reaction with molecular oxygen. Biochemistry 43, 271-281 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 271-281
-
-
Purdy, M.M.1
Koo, L.S.2
Ortiz De-Montellano, P.R.3
Klinman, J.P.4
-
29
-
-
0032574756
-
NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: Characteristics as a soluble microsomal P450 reductase
-
Jenkins, C. M. & Waterman, M. R. NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: characteristics as a soluble microsomal P450 reductase. Biochemistry 37, 6106-6113 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 6106-6113
-
-
Jenkins, C.M.1
Waterman, M.R.2
-
30
-
-
0032855710
-
+ reductase revealed by protein engineering and crystallographic studies
-
+ reductase revealed by protein engineering and crystallographic studies. Nat. Struct. Biol. 6, 847-853, doi:10.1038/12307 (1999).
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 847-853
-
-
Deng, Z.1
-
31
-
-
0034616145
-
Competition between C-terminal tyrosine and nicotinamide modulates pyridine nucleotide affinity and specificity in plant ferredoxin-NADP(+) reductase
-
Piubelli, L. et al. Competition between C-terminal tyrosine and nicotinamide modulates pyridine nucleotide affinity and specificity in plant ferredoxin-NADP(+) reductase. J. Biol. Chem. 275, 10472-10476 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10472-10476
-
-
Piubelli, L.1
-
32
-
-
2442637815
-
Role of the C-terminal tyrosine of ferredoxin-nicotinamide adenine dinucleotide phosphate reductase in the electron transfer processes with its protein partners ferredoxin and flavodoxin
-
Nogues, I. et al. Role of the C-terminal tyrosine of ferredoxin-nicotinamide adenine dinucleotide phosphate reductase in the electron transfer processes with its protein partners ferredoxin and flavodoxin. Biochemistry 43, 6127-6137, doi:10.1021/bi049858h (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 6127-6137
-
-
Nogues, I.1
-
33
-
-
0026513046
-
Nature of biological electron transfer
-
Moser, C. C., Keske, J. M., Warncke, K., Farid, R. S. & Dutton, P. L. Nature of biological electron transfer. Nature 355, 796-802, doi:10.1038/355796a0 (1992).
-
(1992)
Nature
, vol.355
, pp. 796-802
-
-
Moser, C.C.1
Keske, J.M.2
Warncke, K.3
Farid, R.S.4
Dutton, P.L.5
-
34
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
Omura, T. & Sato, R. The Carbon Monoxide-Binding Pigment of Liver Microsomes. I. Evidence for Its Hemoprotein Nature. J. Biol. Chem. 239, 2370-2378 (1964).
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
35
-
-
84874350400
-
Cytochrome P450 reductase from candida apicola: Versatile redox partner for bacterial P450s
-
Girhard, M., Tieves, F., Weber, E., Smit, M. S. & Urlacher, V. B. Cytochrome P450 reductase from Candida apicola: versatile redox partner for bacterial P450s. Appl. Microbiol. Biotechnol. 97, 1625-1635, doi:10.1007/s00253-012-4026-z (2013).
-
(2013)
Appl. Microbiol. Biotechnol.
, vol.97
, pp. 1625-1635
-
-
Girhard, M.1
Tieves, F.2
Weber, E.3
Smit, M.S.4
Urlacher, V.B.5
-
36
-
-
84904130901
-
Selective allylic hydroxylation of acyclic terpenoids by CYP154E1 from thermobifida fusca YX
-
Bogazkaya, A. M. et al. Selective allylic hydroxylation of acyclic terpenoids by CYP154E1 from Thermobifida fusca YX. Beilstein J. Org. Chem. 10, 1347-1353, doi:10.3762/bjoc.10.137 (2014).
-
(2014)
Beilstein J. Org. Chem.
, vol.10
, pp. 1347-1353
-
-
Bogazkaya, A.M.1
-
37
-
-
0036208861
-
Optically active ionones and derivatives: Preparation and olfactory properties
-
Brenna, E., Fuganti, C., Serra, S. & Kraft, P. Optically active ionones and derivatives: Preparation and olfactory properties. Eur. J. Org. Chem., 967-978 (2002).
-
(2002)
Eur. J. Org. Chem.
, pp. 967-978
-
-
Brenna, E.1
Fuganti, C.2
Serra, S.3
Kraft, P.4
-
38
-
-
36549064193
-
Fragrance material review on beta-ionone
-
Lalko, J. et al. Fragrance material review on beta-ionone. Food Chem. Toxicol. 45(Suppl 1), S241-247, doi:10.1016/j.fct.2007.09.052 (2007).
-
(2007)
Food Chem. Toxicol.
, vol.45
, pp. S241-S247
-
-
Lalko, J.1
-
39
-
-
0011478549
-
Biochemical preparation of optically active 4-hydroxy-ionone and its transformation to (S)-6-hydoxy-α-ionone
-
Kakeya, H., Sugai, T. & Ohta, H. Biochemical preparation of optically active 4-hydroxy-ionone and its transformation to (S)-6-hydoxy-α-ionone. Agric. Biol. Chem. 55, 1873-1876 (1991).
-
(1991)
Agric. Biol. Chem.
, vol.55
, pp. 1873-1876
-
-
Kakeya, H.1
Sugai, T.2
Ohta, H.3
-
40
-
-
0011480806
-
Synthesis and chirality of the enantiomeric 6-hydroxy-alpha-ionones and of cis and trans-5,6-dihydroxy-5,6-dihydro-beta-ionones
-
Eschenmoser, W., Uebelhart, P. & Eugster, C. H. Synthesis and Chirality of the Enantiomeric 6-Hydroxy-Alpha-Ionones and of Cis and Trans-5,6-Dihydroxy-5,6-Dihydro-Beta-Ionones. Helv. Chim. Acta 64, 2681-2690 (1981).
-
(1981)
Helv. Chim. Acta
, vol.64
, pp. 2681-2690
-
-
Eschenmoser, W.1
Uebelhart, P.2
Eugster, C.H.3
-
41
-
-
32544456896
-
Biotransformation of beta-ionone by engineered cytochrome P450 BM-3
-
Urlacher, V. B., Makhsumkhanov, A. & Schmid, R. D. Biotransformation of beta-ionone by engineered cytochrome P450 BM-3. Appl. Microbiol. Biotechnol. 70, 53-59 (2006).
-
(2006)
Appl. Microbiol. Biotechnol.
, vol.70
, pp. 53-59
-
-
Urlacher, V.B.1
Makhsumkhanov, A.2
Schmid, R.D.3
-
42
-
-
0017129148
-
Characterization of a cytochrome P-450-dependent steroid hydroxylase system present in bacillus megaterium
-
Berg, A., Gustafsson, J. A. & Ingelman-Sundberg, M. Characterization of a cytochrome P-450-dependent steroid hydroxylase system present in Bacillus megaterium. J. Biol. Chem. 251, 2831-2838 (1976).
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 2831-2838
-
-
Berg, A.1
Gustafsson, J.A.2
Ingelman-Sundberg, M.3
-
43
-
-
49249113945
-
Theoretical and experimental evaluation of a CYP106A2 low homology model and production of mutants with changed activity and selectivity of hydroxylation
-
Lisurek, M., Simgen, B., Antes, I. & Bernhardt, R. Theoretical and experimental evaluation of a CYP106A2 low homology model and production of mutants with changed activity and selectivity of hydroxylation. Chem Bio Chem 9, 1439-1449, doi:10.1002/cbic.200700670 (2008).
-
(2008)
Chem Bio Chem
, vol.9
, pp. 1439-1449
-
-
Lisurek, M.1
Simgen, B.2
Antes, I.3
Bernhardt, R.4
-
44
-
-
84903765191
-
Steroid conversion with CYP106A2 - production of pharmaceutically interesting DHEA metabolites
-
Schmitz, D., Zapp, J. & Bernhardt, R. Steroid conversion with CYP106A2 - production of pharmaceutically interesting DHEA metabolites. Microb. Cell Fact. 13, 81, doi:10.1186/1475-2859-13-81 (2014).
-
(2014)
Microb. Cell Fact.
, vol.13
, pp. 81
-
-
Schmitz, D.1
Zapp, J.2
Bernhardt, R.3
-
45
-
-
84856382805
-
A new bacillus megaterium whole-cell catalyst for the hydroxylation of the pentacyclic triterpene 11-keto-betaboswellic acid (KBA) based on a recombinant cytochrome P450 system
-
Bleif, S. et al. A new Bacillus megaterium whole-cell catalyst for the hydroxylation of the pentacyclic triterpene 11-keto-betaboswellic acid (KBA) based on a recombinant cytochrome P450 system. Appl. Microbiol. Biotechnol. 93, 1135-1146, doi:10.1007/s00253-011-3467-0 (2012).
-
(2012)
Appl. Microbiol. Biotechnol.
, vol.93
, pp. 1135-1146
-
-
Bleif, S.1
-
46
-
-
0028179432
-
Mutations in steroid 21-hydroxylase (CYP21)
-
White, P. C., Tusie-Luna, M. T., New, M. I. & Speiser, P. W. Mutations in steroid 21-hydroxylase (CYP21). Hum. Mutat. 3, 373-378, doi:10.1002/humu.1380030408 (1994).
-
(1994)
Hum. Mutat.
, vol.3
, pp. 373-378
-
-
White, P.C.1
Tusie-Luna, M.T.2
New, M.I.3
Speiser, P.W.4
-
47
-
-
84941639570
-
A CYP21A2 based whole-cell system in Escherichia coli for the biotechnological production of premedrol
-
Brixius-Anderko, S., Schiffer, L., Hannemann, F., Janocha, B. & Bernhardt, R. A CYP21A2 based whole-cell system in Escherichia coli for the biotechnological production of premedrol. Microb. Cell Fact. 14, 135, doi:10.1186/s12934-015-0333-2 (2015).
-
(2015)
Microb. Cell Fact.
, vol.14
, pp. 135
-
-
Brixius-Anderko, S.1
Schiffer, L.2
Hannemann, F.3
Janocha, B.4
Bernhardt, R.5
-
48
-
-
0020064853
-
Routes of flavodoxin and ferredoxin reduction in Escherichia coli. CoA-acylating pyruvate: Flavodoxin and NADPH: Flavodoxin oxidoreductases participating in the activation of pyruvate formatelyase
-
Blaschkowski, H. P., Neuer, G., Ludwig-Festl, M. & Knappe, J. Routes of flavodoxin and ferredoxin reduction in Escherichia coli. CoA-acylating pyruvate: flavodoxin and NADPH: flavodoxin oxidoreductases participating in the activation of pyruvate formatelyase. Eur. J. Biochem. 123, 563-569 (1982).
-
(1982)
Eur. J. Biochem.
, vol.123
, pp. 563-569
-
-
Blaschkowski, H.P.1
Neuer, G.2
Ludwig-Festl, M.3
Knappe, J.4
-
49
-
-
0027771036
-
Flavodoxin is required for the activation of the anaerobic ribonucleotide reductase
-
Bianchi, V. et al. Flavodoxin is required for the activation of the anaerobic ribonucleotide reductase. Biochem. Biophys. Res. Commun. 197, 792-797, doi:10.1006/bbrc.1993.2548 (1993).
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.197
, pp. 792-797
-
-
Bianchi, V.1
-
50
-
-
0029111152
-
Differential activities of heterocyst ferredoxin, vegetative cell ferredoxin, and flavodoxin as electron carriers in nitrogen fixation and photosynthesis in anabaena sp
-
Razquin, P. et al. Differential activities of heterocyst ferredoxin, vegetative cell ferredoxin, and flavodoxin as electron carriers in nitrogen fixation and photosynthesis in Anabaena sp. Photosynth. Res. 43, 35-40, doi:10.1007/BF00029460 (1995).
-
(1995)
Photosynth. Res.
, vol.43
, pp. 35-40
-
-
Razquin, P.1
-
51
-
-
0018858593
-
Electron transport to nitrogenase in klebsiella pneumoniae
-
Nieva-Gomez, D., Roberts, G. P., Klevickis, S. & Brill, W. J. Electron transport to nitrogenase in Klebsiella pneumoniae. Proc. Natl. Acad. Sci. U. S. A. 77, 2555-2558 (1980).
-
(1980)
Proc. Natl. Acad. Sci. U. S. A.
, vol.77
, pp. 2555-2558
-
-
Nieva-Gomez, D.1
Roberts, G.P.2
Klevickis, S.3
Brill, W.J.4
-
52
-
-
0016173119
-
Activation of methionine synthetase by a reduced triphosphopyridine nucleotide-dependent flavoprotein system
-
Fujii, K. & Huennekens, F. M. Activation of methionine synthetase by a reduced triphosphopyridine nucleotide-dependent flavoprotein system. J. Biol. Chem. 249, 6745-6753 (1974).
-
(1974)
J. Biol. Chem.
, vol.249
, pp. 6745-6753
-
-
Fujii, K.1
Huennekens, F.M.2
-
53
-
-
0029047343
-
Biotin synthase from Escherichia coli, an investigation of the low molecular weight and protein components required for activity in vitro
-
Birch, O. M., Fuhrmann, M. & Shaw, N. M. Biotin synthase from Escherichia coli, an investigation of the low molecular weight and protein components required for activity in vitro. J. Biol. Chem. 270, 19158-19165 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19158-19165
-
-
Birch, O.M.1
Fuhrmann, M.2
Shaw, N.M.3
-
54
-
-
0030021995
-
Recombinant human cytochrome P450 1A2 and an N-terminal-truncated form: Construction, purification, aggregation properties, and interactions with flavodoxin, ferredoxin, and NADPH-cytochrome P450 reductase
-
Dong, M. S., Yamazaki, H., Guo, Z. & Guengerich, F. P. Recombinant human cytochrome P450 1A2 and an N-terminal-truncated form: construction, purification, aggregation properties, and interactions with flavodoxin, ferredoxin, and NADPH-cytochrome P450 reductase. Arch. Biochem. Biophys. 327, 11-19, doi:10.1006/abbi.1996.0086 (1996).
-
(1996)
Arch. Biochem. Biophys.
, vol.327
, pp. 11-19
-
-
Dong, M.S.1
Yamazaki, H.2
Guo, Z.3
Guengerich, F.P.4
-
55
-
-
0032211496
-
Characterisation of flavodoxin NADP + oxidoreductase and flavodoxin; key components of electron transfer in Escherichia coli
-
McIver, L. et al. Characterisation of flavodoxin NADP + oxidoreductase and flavodoxin; key components of electron transfer in Escherichia coli. Eur. J. Biochem. 257, 577-585 (1998).
-
(1998)
Eur. J. Biochem.
, vol.257
, pp. 577-585
-
-
McIver, L.1
-
56
-
-
84882976133
-
LICRED: A versatile drop-in vector for rapid generation of redox-self-sufficient cytochromes P450
-
Sabbadin, F., Grogan, G. & Bruce, N. C. LICRED: a versatile drop-in vector for rapid generation of redox-self-sufficient cytochromes P450. Methods Mol. Biol. 987, 239-249, doi:10.1007/978-1-62703-321-3-20 (2013).
-
(2013)
Methods Mol. Biol.
, vol.987
, pp. 239-249
-
-
Sabbadin, F.1
Grogan, G.2
Bruce, N.C.3
-
57
-
-
84934436184
-
Use of sulfolobus solfataricus PCNA subunit proteins to direct the assembly of multimeric enzyme complexes
-
Hirakawa, H. & Nagamune, T. Use of Sulfolobus solfataricus PCNA subunit proteins to direct the assembly of multimeric enzyme complexes. Methods Mol. Biol. 978, 149-163, doi:10.1007/978-1-62703-293-3-11 (2013).
-
(2013)
Methods Mol. Biol.
, vol.978
, pp. 149-163
-
-
Hirakawa, H.1
Nagamune, T.2
-
58
-
-
82755189689
-
Cytochrome P450: Taming a wild type enzyme
-
Jung, S. T., Lauchli, R. & Arnold, F. H. Cytochrome P450: taming a wild type enzyme. Curr. Opin. Biotechnol. 22, 809-817, doi:10.1016/j.copbio.2011.02.008 (2011).
-
(2011)
Curr. Opin. Biotechnol.
, vol.22
, pp. 809-817
-
-
Jung, S.T.1
Lauchli, R.2
Arnold, F.H.3
-
59
-
-
0025350086
-
An investigation of oligopeptides linking domains in protein tertiary structures and possible candidates for general gene fusion
-
Argos, P. An investigation of oligopeptides linking domains in protein tertiary structures and possible candidates for general gene fusion. J. Mol. Biol. 211, 943-958, doi:10.1016/0022-2836(90)90085-Z (1990).
-
(1990)
J. Mol. Biol.
, vol.211
, pp. 943-958
-
-
Argos, P.1
-
60
-
-
0036878154
-
An analysis of protein domain linkers: Their classification and role in protein folding
-
George, R. A. & Heringa, J. An analysis of protein domain linkers: their classification and role in protein folding. Protein Eng. 15, 871-879 (2002).
-
(2002)
Protein Eng.
, vol.15
, pp. 871-879
-
-
George, R.A.1
Heringa, J.2
-
61
-
-
33645741221
-
Improvement of domain linker prediction by incorporating loop-length-dependent characteristics
-
Tanaka, T., Yokoyama, S. & Kuroda, Y. Improvement of domain linker prediction by incorporating loop-length-dependent characteristics. Biopolymers 84, 161-168, doi:10.1002/bip.20361 (2006).
-
(2006)
Biopolymers
, vol.84
, pp. 161-168
-
-
Tanaka, T.1
Yokoyama, S.2
Kuroda, Y.3
-
62
-
-
84874033858
-
Linkers in the structural biology of protein-protein interactions
-
Chichili, V. P. R., Kumar, V. & Sivaraman, J. Linkers in the structural biology of protein-protein interactions. Protein Sci. 22, 153-167, doi:10.1002/pro.2206 (2013).
-
(2013)
Protein Sci.
, vol.22
, pp. 153-167
-
-
Chichili, V.P.R.1
Kumar, V.2
Sivaraman, J.3
-
63
-
-
33750728028
-
Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers
-
Evers, T. H., van Dongen, E. M., Faesen, A. C., Meijer, E. W. & Merkx, M. Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers. Biochemistry 45, 13183-13192, doi:10.1021/bi061288t (2006).
-
(2006)
Biochemistry
, vol.45
, pp. 13183-13192
-
-
Evers, T.H.1
Van Dongen, E.M.2
Faesen, A.C.3
Meijer, E.W.4
Merkx, M.5
-
64
-
-
10344263901
-
Conformations of variably linked chimeric proteins evaluated by synchrotron X-ray small-angle scattering
-
Arai, R., Wriggers, W., Nishikawa, Y., Nagamune, T. & Fujisawa, T. Conformations of variably linked chimeric proteins evaluated by synchrotron X-ray small-angle scattering. Proteins 57, 829-838, doi:10.1002/prot.20244 (2004).
-
(2004)
Proteins
, vol.57
, pp. 829-838
-
-
Arai, R.1
Wriggers, W.2
Nishikawa, Y.3
Nagamune, T.4
Fujisawa, T.5
-
65
-
-
84922211452
-
Design and characterization of structured protein linkers with differing flexibilities
-
Klein, J. S., Jiang, S., Galimidi, R. P., Keeffe, J. R. & Bjorkman, P. J. Design and characterization of structured protein linkers with differing flexibilities. Protein Eng. Des. Sel. 27, 325-330, doi:10.1093/protein/gzu043 (2014).
-
(2014)
Protein Eng. Des. Sel.
, vol.27
, pp. 325-330
-
-
Klein, J.S.1
Jiang, S.2
Galimidi, R.P.3
Keeffe, J.R.4
Bjorkman, P.J.5
-
66
-
-
0035859886
-
Mapping the interactions between flavodoxin and its physiological partners flavodoxin reductase and cobalamindependent methionine synthase
-
Hall, D. A. et al. Mapping the interactions between flavodoxin and its physiological partners flavodoxin reductase and cobalamindependent methionine synthase. Proc. Natl. Acad. Sci. USA. 98, 9521-9526 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9521-9526
-
-
Hall, D.A.1
-
67
-
-
84930225593
-
Mechanistic basis of electron transfer to cytochromes p450 by natural redox partners and artificial donor constructs
-
Hlavica, P. Mechanistic basis of electron transfer to cytochromes p450 by natural redox partners and artificial donor constructs. Adv. Exp. Med. Biol. 851, 247-297, doi:10.1007/978-3-319-16009-2-10 (2015).
-
(2015)
Adv. Exp. Med. Biol.
, vol.851
, pp. 247-297
-
-
Hlavica, P.1
-
68
-
-
85012012714
-
Regioselective hydroxylation of stilbenes by engineered cytochrome P450 from thermobifida fusca YX
-
Rühlmann, A., Antovic, D., Müller, T. J. J. & Urlacher, V. B. Regioselective Hydroxylation of Stilbenes by Engineered Cytochrome P450 from Thermobifida fusca YX. Adv. Synth. Catal. 359, 984-994 (2017).
-
(2017)
Adv. Synth. Catal.
, vol.359
, pp. 984-994
-
-
Rühlmann, A.1
Antovic, D.2
Müller, T.J.J.3
Urlacher, V.B.4
-
69
-
-
84885567349
-
Selective steroid oxyfunctionalisation by CYP154C5, a bacterial cytochrome P450
-
Bracco, P., Janssen, D. B. & Schallmey, A. Selective steroid oxyfunctionalisation by CYP154C5, a bacterial cytochrome P450. Microb. Cell Fact. 12, 95, doi:10.1186/1475-2859-12-95 (2013).
-
(2013)
Microb. Cell Fact.
, vol.12
, pp. 95
-
-
Bracco, P.1
Janssen, D.B.2
Schallmey, A.3
-
70
-
-
84988311278
-
Regioselective C-H hydroxylation of omeprazole sulfide by bacillus megaterium CYP102A1 to produce a human metabolite
-
Jang, H. H. et al. Regioselective C-H hydroxylation of omeprazole sulfide by Bacillus megaterium CYP102A1 to produce a human metabolite. Biotechnol. Lett. 39, 105-112, doi:10.1007/s10529-016-2211-3 (2017).
-
(2017)
Biotechnol. Lett.
, vol.39
, pp. 105-112
-
-
Jang, H.H.1
-
71
-
-
20544450570
-
Catalytic hydroxylation in biphasic systems using CYP102A1 mutants
-
Maurer, S. C. et al. Catalytic hydroxylation in biphasic systems using CYP102A1 mutants. Adv. Synth. Catal. 347, 1090-1098 (2005).
-
(2005)
Adv. Synth. Catal.
, vol.347
, pp. 1090-1098
-
-
Maurer, S.C.1
-
72
-
-
84882286824
-
Regioselective o-hydroxylation of monosubstituted benzenes by P450 BM3
-
Dennig, A., Lülsdorf, N., Liu, H. & Schwaneberg, U. Regioselective o-hydroxylation of monosubstituted benzenes by P450 BM3. Angew. Chem. Int. Ed. Engl. 52, 8459-8462, doi:10.1002/anie.201303986 (2013).
-
(2013)
Angew. Chem. Int. Ed. Engl.
, vol.52
, pp. 8459-8462
-
-
Dennig, A.1
Lülsdorf, N.2
Liu, H.3
Schwaneberg, U.4
-
73
-
-
84992121181
-
A whole cell biocatalyst for double oxidation of cyclooctane
-
Müller, C. A. et al. A whole cell biocatalyst for double oxidation of cyclooctane. J. Ind. Microbiol. Biotechnol. 43, 1641-1646, doi:10.1007/s10295-016-1844-5 (2016).
-
(2016)
J. Ind. Microbiol. Biotechnol.
, vol.43
, pp. 1641-1646
-
-
Müller, C.A.1
-
74
-
-
36148958632
-
Engineered alkane-hydroxylating cytochrome P450(BM3) exhibiting nativelike catalytic properties
-
Fasan, R., Chen, M. M., Crook, N. C. & Arnold, F. H. Engineered alkane-hydroxylating cytochrome P450(BM3) exhibiting nativelike catalytic properties. Angew. Chem. Int. Ed. Engl. 46, 8414-8418 (2007).
-
(2007)
Angew. Chem. Int. Ed. Engl.
, vol.46
, pp. 8414-8418
-
-
Fasan, R.1
Chen, M.M.2
Crook, N.C.3
Arnold, F.H.4
-
75
-
-
78649447680
-
Expression, purification and characterization of two clostridium acetobutylicum flavodoxins: Potential electron transfer partners for CYP152A2
-
Honda Malca, S., Girhard, M., Schuster, S., Durre, P. & Urlacher, V. B. Expression, purification and characterization of two Clostridium acetobutylicum flavodoxins: Potential electron transfer partners for CYP152A2. Biochim. Biophys. Acta 1814, 257-264, doi:10.1016/j.bbapap.2010.06.013 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.1814
, pp. 257-264
-
-
Honda Malca, S.1
Girhard, M.2
Schuster, S.3
Durre, P.4
Urlacher, V.B.5
-
76
-
-
2642562736
-
Identification of monohydroxy progesterones produced by CYP106A2 using comparative HPLC and electrospray ionisation collision-induced dissociation mass spectrometry
-
Lisurek, M., Kang, M. J., Hartmann, R. W. & Bernhardt, R. Identification of monohydroxy progesterones produced by CYP106A2 using comparative HPLC and electrospray ionisation collision-induced dissociation mass spectrometry. Biochem. Biophys. Res. Commun. 319, 677-682 (2004).
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.319
, pp. 677-682
-
-
Lisurek, M.1
Kang, M.J.2
Hartmann, R.W.3
Bernhardt, R.4
|