Leptin in hippocampus mediates benefits of mild exercise by an antioxidant on neurogenesis and memory

Proceedings of the National Academy of Sciences of the United States of America

Volumn 166, Issue 22, 2019, Pages 10988-10993

  Yook, Jang Soo ^a   Rakwal, Randeep ^a   Shibato, Junko ^a   Takahashi, Kanako ^a   Koizumi, Hikaru ^a   Shima, Takeru ^a   Ikemoto, Mitsushi J ^b,c   Oharomari, Leandro K ^a   McEwen, Bruce S ^d   Soya, Hideaki ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c TOHO UNIVERSITY   (Japan)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Antioxidant; Astaxanthin; Hippocampal leptin; Mild exercise; Spatial memory

Indexed keywords

ANTIOXIDANT; ASTAXANTHIN; LEPTIN; PROTEIN KINASE B; STAT3 PROTEIN; XANTHOPHYLL;

ABHD3 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOINFORMATICS; CELL VIABILITY; CONTROLLED STUDY; DIETARY INTAKE; DNA MICROARRAY; DRUG MECHANISM; DRUG POTENTIATION; EXERCISE INTENSITY; GENE; GENE CONTROL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HORMONE ACTION; HUMAN; HUMAN CELL; LATERAL BRAIN VENTRICLE; LEP GENE; LEPTIN DEFICIENCY; MEMORY DISORDER; MOUSE; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEUROBLASTOMA CELL LINE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPATIAL MEMORY; TREATMENT DURATION; UPREGULATION; ANIMAL; CELL SURVIVAL; DRUG EFFECT; METABOLISM; TUMOR CELL LINE;

ANIMALS; ANTIOXIDANTS; CELL LINE, TUMOR; CELL SURVIVAL; HIPPOCAMPUS; HUMANS; LEPTIN; MICE; NEUROGENESIS; PHYSICAL CONDITIONING, ANIMAL; SPATIAL MEMORY; XANTHOPHYLLS;

EID: 85066241685     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1815197116     Document Type: Article

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