BDNF induction with mild exercise in the rat hippocampus

Biochemical and Biophysical Research Communications

Volumn 358, Issue 4, 2007, Pages 961-967

  Soya, Hideaki ^a   Nakamura, Toru ^a   Deocaris, Custer C ^a   Kimpara, Akiyo ^a   Iimura, Miho ^a   Fujikawa, Takahiko ^b   Chang, Hyukki ^a   McEwen, Bruce S ^c   Nishijima, Takeshi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Acute mild exercise; BDNF; c fos; Corticosterone; Hippocampus; Lactate threshold; Treadmill running

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; LACTIC ACID; MESSENGER RNA; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; EXERCISE TEST; HIPPOCAMPUS; LACTATE BLOOD LEVEL; MALE; NERVE CELL; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; RUNNING; TREADMILL EXERCISE; UPREGULATION;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; EXERTION; HIPPOCAMPUS; MALE; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, WISTAR; RUNNING;

ANIMALIA; RATTUS;

EID: 34249709339     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.04.173     Document Type: Article

References (31)

1. van Praag H., Kempermann G., and Gage F.H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 2 (1999) 266-270
2. Lazarov O., Robinson J., Tang Y.P., Hairston I.S., Korade-Mirnics Z., Lee V.M., Hersh L.B., Sapolsky R.M., Mirnics K., and Sisodia S.S. Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell 120 (2005) 701-713
3. Ernfors P., Ibanez C.F., Ebendal T., Olson L., and Persson H. Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain. Proc. Natl. Acad. Sci. USA 87 (1990) 5454-5458
4. Lu B. Pro-region of neurotrophins: role in synaptic modulation. Neuron 39 (2003) 735-738
5. Soule J., Messaoudi E., and Bramham C.R. Brain-derived neurotrophic factor and control of synaptic consolidation in the adult brain. Biochem. Soc. Trans. 34 (2006) 600-604
6. Vaynman S., Ying Z., and Gomez-Pinilla F. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. Eur. J. Neurosci. 20 (2004) 2580-2590
7. Gomez-Pinilla F., Ying Z., Roy R.R., Molteni R., and Edgerton V.R. Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity. J. Neurophysiol. 88 (2002) 2187-2195
8. Cotman C.W., and Berchtold N.C. Exercise: a behavioral intervention to enhance brain health and plasticity. Trends Neurosci. 25 (2002) 295-301
9. Saito T., and Soya H. Delineation of responsive AVP-containing neurons to running stress in the hypothalamus. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286 (2004) R484-R490
10. H. Soya, A. Mukai, C.C. Deocaris, N. Ohiwa, H. Chang, T. Nishijima, T. Fujikawa, K. Togashi, T. Saito, Threshold-like pattern of neuronal activation in the hypothalamus during treadmill running: establishment of a minimum running stress (MRS) rat model. Neurosci. Res. (2007), doi:10.1016/j.neures.2007.04.004.
11. Kawashima H., Saito T., Yoshizato H., Fujikawa T., Sato Y., McEwen B.S., and Soya H. Endurance treadmill training in rats alters CRH activity in the hypothalamic paraventricular nucleus at rest and during acute running according to its period. Life Sci. 76 (2004) 763-774
12. Friedman W.J., Olson L., and Persson H. Cells that express brain-derived neurotrophic factor mRNA in the developing postnatal rat brain. Eur. J. Neurosci. 3 (1991) 688-697
13. Imaki T., Shibasaki T., Hotta M., and Demura H. Early induction of c-fos precedes increased expression of corticotropin-releasing factor messenger ribonucleic acid in the paraventricular nucleus after immobilization stress. Endocrinology 131 (1992) 240-246
14. Smith M.A., Makino S., Kim S.Y., and Kvetnansky R. Stress increases brain-derived neurotropic factor messenger ribonucleic acid in the hypothalamus and pituitary. Endocrinology 136 (1995) 3743-3750
15. Paxinos G., and Watson C. The Rat Brain. fourth ed. (1998), Academic Press, San Diego
16. Huang A.M., Jen C.J., Chen H.F., Yu L., Kuo Y.M., and Chen H.I. Compulsive exercise acutely upregulates rat hippocampal brain derived neurotrophic factor. J. Neural Transm. 113 (2006) 803-811
17. Lee T.H., Jang M.H., Shin M.C., Lim B.V., Kim Y.P., Kim H., Choi H.H., Lee K.S., Kim E.H., and Kim C.J. Dependence of rat hippocampal c-Fos expression on intensity and duration of exercise. Life Sci. 72 (2003) 1421-1436
18. Kamondi A., Acsady L., and Buzsaki G. Dendritic spikes are enhanced by cooperative network activity in the intact hippocampus. J. Neurosci. 18 (1998) 3919-3928
19. McEwen B.S. Stress and hippocampal plasticity. Annu. Rev. Neurosci. 22 (1999) 105-122
20. Zhang J., Zhang D., McQuade J.S., Behbehani M., Tsien J.Z., and Xu M. c-fos regulates neuronal excitability and survival. Nat. Genet. 30 (2002) 416-420
21. Dong M., Wu Y., Fan Y., Xu M., and Zhang J. c-fos modulates brain-derived neurotrophic factor mRNA expression in mouse hippocampal CA3 and dentate gyrus neurons. Neurosci. Lett. 400 (2006) 177-180
22. Santi S., Cappello S., Riccio M., Bergami M., Aicardi G., Schenk U., Matteoli M., and Canossa M. Hippocampal neurons recycle BDNF for activity-dependent secretion and LTP maintenance. EMBO J. 25 (2006) 4372-4380
23. Marmigere F., Givalois L., Rage F., Arancibia S., and Tapia-Arancibia L. Rapid induction of BDNF expression in the hippocampus during immobilization stress challenge in adult rats. Hippocampus 13 (2003) 646-655
24. Schaaf M.J., de Jong J., de Kloet E.R., and Vreugdenhil E. Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone. Brain Res. 813 (1998) 112-120
25. Jacobsen J.P., and Mork A. Chronic corticosterone decreases brain-derived neurotrophic factor (BDNF) mRNA and protein in the hippocampus, but not in the frontal cortex, of the rat. Brain Res. 1110 (2006) 221-225
26. Hansson A.C., Sommer W.H., Metsis M., Stromberg I., Agnati L.F., and Fuxe K. Corticosterone actions on the hippocampal brain-derived neurotrophic factor expression are mediated by exon IV promoter. J. Neuroendocrinol. 18 (2006) 104-114
27. Stranahan A.M., Khalil D., and Gould E. Social isolation delays the positive effects of running on adult neurogenesis. Nat. Neurosci. 9 (2006) 526-533
28. Nishijima T., and Soya H. Evidence of functional hyperemia in the rat hippocampus during mild treadmill running. Neurosci. Res. 54 (2006) 186-191
29. Hillman C.H., Snook E.M., and Jerome G.J. Acute cardiovascular exercise and executive control function. Int. J. Psychophysiol. 48 (2003) 307-314
30. Tomporowski P.D. Effects of acute bouts of exercise on cognition. Acta Psychol. (Amst) 112 (2003) 297-324
31. Murray K.D., Gall C.M., Jones E.G., and Isackson P.J. Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease. Neuroscience 60 (1994) 37-48