Mild exercise increases dihydrotestosterone in hippocampus providing evidence for androgenic mediation of neurogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 32, 2012, Pages 13100-13105

  Okamoto, Masahiro ^a   Hojo, Yasushi ^b   Inoue, Koshiro ^a   Matsui, Takashi ^a   Kawato, Suguru ^b   McEwen, Bruce S ^c   Soya, Hideaki ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

De novo synthesis; Exercise induced neurogenesis; Low intensity exercise; Neurosteroid; Paracrine

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; DOUBLECORTIN; FLUTAMIDE; MESSENGER RNA; SESAME SEED OIL; STEROID 5ALPHA REDUCTASE 1; STEROID 5ALPHA REDUCTASE 2; TAMOXIFEN; TESTOSTERONE;

ANDROGEN SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MASS SPECTROMETRY; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; ORCHIECTOMY; PRIORITY JOURNAL; RAT; SHAM PROCEDURE; TESTOSTERONE BLOOD LEVEL; TREADMILL EXERCISE;

3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; AGE FACTORS; ANIMALS; BROMODEOXYURIDINE; DIHYDROTESTOSTERONE; HIPPOCAMPUS; MALE; MASS SPECTROMETRY; MEMBRANE PROTEINS; MOTOR ACTIVITY; NEUROGENESIS; NEURONS; ORCHIECTOMY; RATS; RECEPTORS, ANDROGEN; TAMOXIFEN;

ANIMALIA; RATTUS;

EID: 84864724018     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210023109     Document Type: Article

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