Neuronal Activity Drives Localized Blood-Brain-Barrier Transport of Serum Insulin-like Growth Factor-I into the CNS

Neuron

Volumn 67, Issue 5, 2010, Pages 834-846

  Nishijima, Takeshi ^a   Piriz, Joaquin ^a   Duflot, Sylvie ^a   Fernandez, Ana M ^a   Gaitan, Gema ^a   Gomez Pinedo, Ulises ^b   Verdugo, Jose M Garcia ^b   Leroy, Felix ^a   Soya, Hideaki ^c   Nuñez, Angel ^d   Torres Aleman, Ignacio ^a  

^a INSTITUTO CAJAL   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Molneuro; Signaling; Sysneuro

Indexed keywords

GELATINASE B; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; AMINO ACID RECEPTOR BLOCKING AGENT; DIGOXIGENIN; GLUTAMIC ACID; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; NERVE PROTEIN; SOMATOMEDIN C RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CEREBELLAR PEDUNCLE; DENSITOMETRY; IMMUNOGOLD LABELING; IMMUNOPRECIPITATION; MALE; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN CLEAVAGE; PROTEIN TRANSPORT; RAT; SOMATOSENSORY CORTEX; ACTION POTENTIAL; ANALYSIS OF VARIANCE; ANIMAL; BIOPHYSICS; BLOOD FLOW; BODY TEMPERATURE; CELL CULTURE; COCULTURE; DRUG EFFECTS; DRUG INTERACTION; ELECTROSTIMULATION; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GLIA; HEMISPHERIC DOMINANCE; HUMAN; IMMUNOELECTRON MICROSCOPY; INNERVATION; METABOLISM; MICRODIALYSIS; NERVE CELL; NERVE TRACT; PHYSIOLOGY; PROCEDURES; TIME; ULTRASTRUCTURE; VIBRISSA; WISTAR RAT;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; ANIMALS; BIOPHYSICS; BLOOD-BRAIN BARRIER; BODY TEMPERATURE; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; COCULTURE TECHNIQUES; DIGOXIGENIN; DRUG INTERACTIONS; ELECTRIC STIMULATION; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXCITATORY AMINO ACID ANTAGONISTS; FUNCTIONAL LATERALITY; GLUTAMIC ACID; HUMANS; IMMUNOPRECIPITATION; INSULIN-LIKE GROWTH FACTOR I; LDL-RECEPTOR RELATED PROTEIN 1; MATRIX METALLOPROTEINASE 9; MICRODIALYSIS; MICROSCOPY, IMMUNOELECTRON; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; NEUROGLIA; NEURONS; PROTEIN TRANSPORT; RATS; RATS, WISTAR; RECEPTOR, IGF TYPE 1; REGIONAL BLOOD FLOW; TIME FACTORS; VIBRISSAE; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-1;

EID: 77956298301     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2010.08.007     Document Type: Article

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