A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology

Cell

Volumn 177, Issue 5, 2019, Pages 1217-1231.e18

  Chen, Haiwei ^a   Nwe, Phu Khat ^b   Yang, Yi ^a   Rosen, Connor E ^a   Bielecka, Agata A ^a   Kuchroo, Manik ^a   Cline, Gary W ^a   Kruse, Andrew C ^c   Ring, Aaron M ^a   Crawford, Jason M ^a,b   Palm, Noah W ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 56; G PROTEIN COUPLED RECEPTOR 97; HISTAMINE; HISTIDINE; MONOAMINE OXIDASE INHIBITOR; PHENETHYLAMINE; UNCLASSIFIED DRUG; ADGRG3 PROTEIN, HUMAN; GPR56 PROTEIN, MOUSE;

ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; COLON MOTILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC SCREENING; HIGH THROUGHPUT SCREENING; HOST PATHOGEN INTERACTION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTESTINE FLORA; LACTOBACILLUS REUTERI; MORGANELLA MORGANII; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BACTERIUM; COLON; GROWTH, DEVELOPMENT AND AGING; HEK293 CELL LINE; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

ANIMALS; BACTERIA; COLON; GASTROINTESTINAL MICROBIOME; HEK293 CELLS; HOST MICROBIAL INTERACTIONS; HUMANS; MICE; RECEPTORS, G-PROTEIN-COUPLED;

EID: 85065520847     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2019.03.036     Document Type: Article

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