Histamine-secreting microbes are increased in the gut of adult asthma patients

Journal of Allergy and Clinical Immunology

Volumn 138, Issue 5, 2016, Pages 1491-1494.e7

  Barcik, Weronika ^a   Pugin, Benoit ^a   Westermann, Patrick ^a   Perez, Noelia Rodriguez ^a   Ferstl, Ruth ^a   Wawrzyniak, Marcin ^a   Smolinska, Sylwia ^b   Jutel, Marek ^b   Hessel, Edith M ^c   Michalovich, David ^c   Akdis, Cezmi A ^a,d   Frei, Remo ^a,d   O'Mahony, Liam ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b WROCLAW MEDICAL UNIVERSITY   (Poland)

^c GLAXOSMITHKLINE   (United Kingdom)

^d CHRISTINE KÜHNE CENTER FOR ALLERGY RESEARCH AND EDUCATION CK CARE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE; HISTIDINE DECARBOXYLASE;

ADULT; ADULT DISEASE; ARTICLE; ASTHMA; BACTERIAL GROWTH; BACTERIAL STRAIN; DISEASE SEVERITY; ENTEROBACTER AEROGENES; ENTEROCOCCUS DURANS; ESCHERICHIA COLI; EX VIVO STUDY; FEMALE; HUMAN; INTESTINE FLORA; LACTOBACILLUS; LACTOBACILLUS CASEI; LACTOBACILLUS VAGINALIS; MALE; MORGANELLA MORGANII; PRIORITY JOURNAL; CASE CONTROL STUDY; FECES; HOST PATHOGEN INTERACTION; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

ADULT; ASTHMA; CASE-CONTROL STUDIES; FECES; FEMALE; GASTROINTESTINAL MICROBIOME; HISTAMINE; HOST-PATHOGEN INTERACTIONS; HUMANS; MALE;

EID: 84994159084     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2016.05.049     Document Type: Article

References (9)

1. 1 Huang, Y.J., Boushey, H.A., The microbiome in asthma. J Allergy Clin Immunol 135 (2015), 25–30.
2. 2 Arrieta, M.C., Stiemsma, L.T., Dimitriu, P.A., Thorson, L., Russell, S., Yurist-Doutsch, S., et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci Transl Med, 7, 2015, 307ra152.
3. 3 O'Mahony, L., Akdis, M., Akdis, C.A., Regulation of the immune response and inflammation by histamine and histamine receptors. J Allergy Clin Immunol 128 (2011), 1153–1162.
4. 4 Ferstl, R., Frei, R., Schiavi, E., Konieczna, P., Barcik, W., Ziegler, M., et al. Histamine receptor 2 is a key influence in immune responses to intestinal histamine-secreting microbes. J Allergy Clin Immunol 134 (2014), 744–746.
5. 5 Gao, C., Major, A., Rendon, D., Lugo, M., Jackson, V., Shi, Z., et al. Histamine H2 receptor-mediated suppression of intestinal inflammation by probiotic Lactobacillus reuteri. MBio 6 (2015), e01358–e01415.
6. 6 Smolinska, S., Jutel, M., Crameri, R., O'Mahony, L., Histamine and gut mucosal immune regulation. Allergy 69 (2014), 273–281.
7. 7 Marsland, B.J., Trompette, A., Gollwitzer, E.S., The gut-lung axis in respiratory disease. Ann Am Thorac Soc 12 (2015), S150–S156.
8. 8 Frei, R., Lauener, R.P., Crameri, R., O'Mahony, L., Microbiota and dietary interactions: an update to the hygiene hypothesis?. Allergy 67 (2012), 451–461.
9. 9 Feng, C., Teuber, S., Gershwin, M.E., Histamine (Scombroid) fish poisoning: a comprehensive review. Clin Rev Allergy Immunol 50 (2016), 64–69.