Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection

Cell Host and Microbe

Volumn 25, Issue 5, 2019, Pages 756-765.e5

  Saleh, Mahmoud M ^a   Frisbee, Alyse L ^a   Leslie, Jhansi L ^b   Buonomo, Erica L ^a   Cowardin, Carrie A ^a   Ma, Jennie Z ^b   Simpson, Morgan E ^b   Scully, Kenneth W ^b   Abhyankar, Mayuresh M ^b   Petri, William A ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

adaptive immunity; CD4 T cells; Clostridium difficile; colitis; DSS; IL 17A; IL 23; IL 6; inflammatory bowel disease; Th17 cells

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 4; INTERLEUKIN 6; IL23A PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; INTERLEUKIN 23P19;

ADOLESCENT; ADOPTIVE TRANSFER; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CHILD; CLOSTRIDIUM DIFFICILE INFECTION; COLITIS; COMORBIDITY; CONTROLLED STUDY; DISEASE SEVERITY; HUMAN; INFECTION RISK; INTENSIVE CARE UNIT; LEUKOCYTE COUNT; LIMIT OF DETECTION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; TH17 CELL; ANIMAL; BLOOD; CLOSTRIDIOIDES DIFFICILE; CLOSTRIDIUM INFECTION; COMPLICATION; DISEASE MODEL; DISEASE PREDISPOSITION; FEMALE; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; INFLAMMATORY BOWEL DISEASE; MALE; MIDDLE AGED; MORTALITY; PATHOLOGY; RISK ASSESSMENT; SURVIVAL ANALYSIS; YOUNG ADULT;

ADOLESCENT; ADOPTIVE TRANSFER; ADULT; AGED; ANIMALS; CHILD; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; COLITIS; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; FEMALE; HUMANS; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-23 SUBUNIT P19; INTERLEUKIN-6; MALE; MICE; MIDDLE AGED; RISK ASSESSMENT; SURVIVAL ANALYSIS; TH17 CELLS; YOUNG ADULT;

EID: 85064841521     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2019.03.003     Document Type: Article

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