Interleukin-23 (IL-23), independent of IL-17 and IL-22, drives neutrophil recruitment and innate inflammation during Clostridium difficile colitis in mice

Immunology

Volumn 147, Issue 1, 2016, Pages 114-124

  McDermott, Andrew J ^a   Falkowski, Nicole R ^a   McDonald, Roderick A ^a   Pandit, Chinmay R ^a   Young, Vincent B ^a   Huffnagle, Gary B ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Clostridium difficile; Colitis; Innate inflammation; Mucosal inflammation; Neutrophils

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN DELTA; CD11B ANTIGEN; CEFOPERAZONE; CHEMOATTRACTANT; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 23; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; TUMOR NECROSIS FACTOR; AUTACOID; IL17A PROTEIN, MOUSE; IL23A PROTEIN, MOUSE; INTERLEUKIN 23P19; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; MONOCLONAL ANTIBODY; PROTEIN; REG3G PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLOSTRIDIUM DIFFICILE INFECTION; COLITIS; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HISTOPATHOLOGY; MALE; MOUSE; MUCOSA INFLAMMATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; COLON; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; INTESTINE MUCOSA; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; NEUTROPHIL; PATHOGENICITY; PATHOLOGY; PEPTOCLOSTRIDIUM DIFFICILE; PSEUDOMEMBRANOUS COLITIS; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; CLOSTRIDIUM DIFFICILE; COLON; DISEASE MODELS, ANIMAL; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FEMALE; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; INTERLEUKIN-17; INTERLEUKIN-23 SUBUNIT P19; INTERLEUKINS; INTESTINAL MUCOSA; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; NEUTROPHILS; PROTEINS; SIGNAL TRANSDUCTION;

EID: 84955194088     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12545     Document Type: Article

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