Laboratory evolution to alternating substrate environments yields distinct phenotypic and genetic adaptive strategies

Applied and Environmental Microbiology

Volumn 83, Issue 13, 2017, Pages

  Sandberg, Troy E ^a   Lloyd, Colton J ^a   Palsson, Bernhard O ^a,b   Feist, Adam M ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Chalmers University of Technology   (Denmark)

Author keywords

Adaptive laboratory evolution; Adaptive mutations; Escherichia coli; Phenotypic variation

Indexed keywords

BATCH CELL CULTURE; CARBON; ESCHERICHIA COLI; GENE EXPRESSION; GENES; METABOLISM;

ADAPTATION STRATEGIES; ADAPTIVE LABORATORY EVOLUTION; ADAPTIVE MUTATION; BIOPROCESSING APPLICATIONS; GENE EXPRESSION DATA; GENOME SCALE METABOLIC MODEL; NUTRIENT CONDITIONS; PHENOTYPIC VARIATIONS;

SUBSTRATES;

ADAPTATION; BACTERIUM; FITNESS; GENE EXPRESSION; MUTATION; PHENOTYPE; PHENOTYPIC PLASTICITY; POPULATION DYNAMICS;

ESCHERICHIA COLI;

GLUCOSE; GLYCEROL; XYLOSE;

BACTERIAL GENOME; CULTURE MEDIUM; ENVIRONMENT; ESCHERICHIA COLI; GENETICS; METABOLISM; PHENOTYPE; REPRODUCTIVE FITNESS;

CULTURE MEDIA; ENVIRONMENT; ESCHERICHIA COLI; GENETIC FITNESS; GENOME, BACTERIAL; GLUCOSE; GLYCEROL; PHENOTYPE; XYLOSE;

EID: 85020503243     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.00410-17     Document Type: Article

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