Global metabolic network reorganization by adaptive mutations allows fast growth of Escherichia coli on glycerol

Nature Communications

Volumn 5, Issue , 2014, Pages

  Cheng, Kian Kai ^a,b   Lee, Baek Seok ^a,g   Masuda, Takeshi ^a,h   Ito, Takuro ^a,c   Ikeda, Kazutaka ^a   Hirayama, Akiyoshi ^a   Deng, Lingli ^d   Dong, Jiyang ^d   Shimizu, Kazuyuki ^a,e   Soga, Tomoyoshi ^a   Tomita, Masaru ^a   Palsson, Bernhard O ^f   Robert, Martin ^a,i  

^a KEIO UNIVERSITY   (Japan)

^b UNIVERSITI TEKNOLOGI MALAYSIA   (Malaysia)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d XIAMEN UNIVERSITY   (China)

^e KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^g CJ Corporation   (South Korea)

^h HARVARD MEDICAL SCHOOL   (United States)

ⁱ TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CYCLIC AMP; DEOXYADENOSINE DIPHOSPHATE; GLYCEROL; NICOTINAMIDE; PUTRESCINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; BETA' SUBUNIT OF RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE; ESCHERICHIA COLI PROTEIN; GLYCEROL KINASE;

ADAPTATION; ALLELE; CELLS AND CELL COMPONENTS; GENE EXPRESSION; GENOME; GROWTH RATE; METABOLISM; MICROBIAL COMMUNITY; MUTATION;

ACIDITY; ADAPTATION; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL MUTATION; BIOMASS CONVERSION; BIOMASS PRODUCTION; CARBON SOURCE; CARBON UTILIZATION; CATABOLITE REPRESSION; CELL PROLIFERATION; CELL SIZE; CITRIC ACID CYCLE; CYCLOPROPANATION; ENZYME ACTIVITY; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; GENE DELETION; GENOTYPE; GLUCONEOGENESIS; GROWTH RATE; LIPID COMPOSITION; METABOLISM; MOLECULAR EVOLUTION; NITROGEN METABOLISM; NONHUMAN; OXIDATION REDUCTION STATE; POINT MUTATION; PROTEIN EXPRESSION; PYRIMIDINE SYNTHESIS; STRESS; BIOMASS; GENETICS; GROWTH, DEVELOPMENT AND AGING; MUTATION;

ESCHERICHIA COLI;

ADAPTATION, BIOLOGICAL; BIOMASS; DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GLYCEROL; GLYCEROL KINASE; MUTATION;

EID: 84928889593     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4233     Document Type: Article

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