Solubility and Permeability Improvement of Quercetin by an Interaction Between α-Glucosyl Stevia Nanoaggregates and Hydrophilic Polymer

Journal of Pharmaceutical Sciences

Volumn 108, Issue 6, 2019, Pages 2033-2040

  Uchiyama, Hiromasa ^a   Wada, Yuhei ^a   Hatanaka, Yuta ^a   Hirata, Yoshiyuki ^a   Taniguchi, Masahiko ^a   Kadota, Kazunori ^a   Tozuka, Yuichi ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

composite; hydrophilic polymer; permeability enhancement; quercetin; solubility enhancement; glucosyl stevia

Indexed keywords

ALPHA GLUCOSYL STEVIA; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; POLYMER; POVIDONE; QUERCETIN; UNCLASSIFIED DRUG; ANTIOXIDANT; CELLULOSE; DRUG CARRIER; GLUCOSIDE; KAURANE DERIVATIVE; POLYVINYLPYROLLIDON K30; STEVIOSIDE;

ADSORPTION; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DISPERSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; EVAPORATION; HYDROPHILICITY; INCUBATION TIME; SCANNING ELECTRON MICROSCOPY; SPECTROFLUOROMETRY; X RAY DIFFRACTION; CACO-2 CELL LINE; CELL MEMBRANE PERMEABILITY; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECT; HUMAN; SOLUBILITY;

ANTIOXIDANTS; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CELLULOSE; DITERPENES, KAURANE; DRUG CARRIERS; GLUCOSIDES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; HYPROMELLOSE DERIVATIVES; POVIDONE; QUERCETIN; SOLUBILITY;

EID: 85061059571     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1016/j.xphs.2019.01.007     Document Type: Article

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