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Volumn 10, Issue 12, 2018, Pages

CD8+ T cells responding to the middle east respiratory syndrome coronavirus nucleocapsid protein delivered by vaccinia virus MVA in mice

Author keywords

MERS CoV; MERS CoV nucleocapsid protein; Murine CD8+ T cell epitope; MVA vaccine

Indexed keywords

GAMMA INTERFERON; MODIFIED VACCINIA VIRUS ANKARA 5T4 VACCINE; MODIFIED VACCINIA VIRUS ANKARA MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS N PROTEIN VACCINE; NUCLEOCAPSID PROTEIN; RECOMBINANT PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; VIRUS SPIKE PROTEIN; EPITOPE; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS VACCINE;

EID: 85058759282     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v10120718     Document Type: Article
Times cited : (35)

References (69)
  • 3
    • 85046262643 scopus 로고    scopus 로고
    • MERS transmission and risk factors: A systematic review
    • Park, J.E.; Jung, S.; Kim, A.; Park, J.E. MERS transmission and risk factors: A systematic review. BMC Public Health 2018, 18, 574. [CrossRef] [PubMed]
    • (2018) BMC Public Health , vol.18 , pp. 574
    • Park, J.E.1    Jung, S.2    Kim, A.3    Park, J.E.4
  • 7
    • 84938856608 scopus 로고    scopus 로고
    • 2015 MERS outbreak in Korea: Hospital-to-hospital transmission
    • Ki, M. 2015 MERS outbreak in Korea: Hospital-to-hospital transmission. Epidemiol. Health 2015, 37, e2015033. [CrossRef] [PubMed]
    • (2015) Epidemiol. Health , vol.37
    • Ki, M.1
  • 8
    • 85058666131 scopus 로고    scopus 로고
    • Healthcare-associated infections: The hallmark of Middle East respiratory syndrome coronavirus with review of the literature
    • Al-Tawfiq, J.A.; Auwaerter, P.G. Healthcare-associated infections: The hallmark of Middle East respiratory syndrome coronavirus with review of the literature. J. Hosp. Infect. 2018. [CrossRef]
    • (2018) J. Hosp. Infect.
    • Al-Tawfiq, J.A.1    Auwaerter, P.G.2
  • 13
    • 84908541954 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus: Epidemiology and disease control measures
    • Al-Tawfiq, J.A.; Memish, Z.A. Middle East respiratory syndrome coronavirus: Epidemiology and disease control measures. Infect. Drug Resist. 2014, 7, 281–287. [CrossRef] [PubMed]
    • (2014) Infect. Drug Resist. , vol.7 , pp. 281-287
    • Al-Tawfiq, J.A.1    Memish, Z.A.2
  • 15
    • 85041500705 scopus 로고    scopus 로고
    • Development of Middle East Respiratory Syndrome Coronavirus vaccines—Advances and challenges
    • Cho, H.; Excler, J.L.; Kim, J.H.; Yoon, I.K. Development of Middle East Respiratory Syndrome Coronavirus vaccines—Advances and challenges. Hum. Vaccin. Immunother. 2018, 14, 304–313. [CrossRef] [PubMed]
    • (2018) Hum. Vaccin. Immunother. , vol.14 , pp. 304-313
    • Cho, H.1    Excler, J.L.2    Kim, J.H.3    Yoon, I.K.4
  • 17
    • 0035120566 scopus 로고    scopus 로고
    • Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis
    • Kolb, A.F.; Pewe, L.; Webster, J.; Perlman, S.; Whitelaw, C.B.; Siddell, S.G. Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis. J. Virol. 2001, 75, 2803–2809. [CrossRef] [PubMed]
    • (2001) J. Virol. , vol.75 , pp. 2803-2809
    • Kolb, A.F.1    Pewe, L.2    Webster, J.3    Perlman, S.4    Whitelaw, C.B.5    Siddell, S.G.6
  • 18
    • 0025724967 scopus 로고
    • A conserved coronavirus epitope, critical in virus neutralization, mimicked by internal-image monoclonal anti-idiotypic antibodies
    • Sune, C.; Smerdou, C.; Anton, I.M.; Abril, P.; Plana, J.; Enjuanes, L. A conserved coronavirus epitope, critical in virus neutralization, mimicked by internal-image monoclonal anti-idiotypic antibodies. J. Virol. 1991, 65, 6979–6984.
    • (1991) J. Virol. , vol.65 , pp. 6979-6984
    • Sune, C.1    Smerdou, C.2    Anton, I.M.3    Abril, P.4    Plana, J.5    Enjuanes, L.6
  • 19
    • 2342538530 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus spike protein expressed by attenuated vaccinia virus protectively immunizes mice
    • Bisht, H.; Roberts, A.; Vogel, L.; Bukreyev, A.; Collins, P.L.; Murphy, B.R.; Subbarao, K.; Moss, B. Severe acute respiratory syndrome coronavirus spike protein expressed by attenuated vaccinia virus protectively immunizes mice. Proc. Natl. Acad. Sci. USA 2004, 101, 6641–6646. [CrossRef]
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 6641-6646
    • Bisht, H.1    Roberts, A.2    Vogel, L.3    Bukreyev, A.4    Collins, P.L.5    Murphy, B.R.6    Subbarao, K.7    Moss, B.8
  • 20
    • 1842589262 scopus 로고    scopus 로고
    • A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice
    • Yang, Z.Y.; Kong, W.P.; Huang, Y.; Roberts, A.; Murphy, B.R.; Subbarao, K.; Nabel, G.J. A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. Nature 2004, 428, 561–564. [CrossRef]
    • (2004) Nature , vol.428 , pp. 561-564
    • Yang, Z.Y.1    Kong, W.P.2    Huang, Y.3    Roberts, A.4    Murphy, B.R.5    Subbarao, K.6    Nabel, G.J.7
  • 21
    • 84945911336 scopus 로고    scopus 로고
    • A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform
    • Malczyk, A.H.; Kupke, A.; Prufer, S.; Scheuplein, V.A.; Hutzler, S.; Kreuz, D.; Beissert, T.; Bauer, S.; Hubich-Rau, S.; Tondera, C.; et al. A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform. J. Virol. 2015, 89, 11654–11667. [CrossRef]
    • (2015) J. Virol. , vol.89 , pp. 11654-11667
    • Malczyk, A.H.1    Kupke, A.2    Prufer, S.3    Scheuplein, V.A.4    Hutzler, S.5    Kreuz, D.6    Beissert, T.7    Bauer, S.8    Hubich-Rau, S.9    Tondera, C.10
  • 22
    • 84939810764 scopus 로고    scopus 로고
    • A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates
    • Muthumani, K.; Falzarano, D.; Reuschel, E.L.; Tingey, C.; Flingai, S.; Villarreal, D.O.; Wise, M.; Patel, A.; Izmirly, A.; Aljuaid, A.; et al. A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Sci. Transl. Med. 2015, 7, 301ra132. [CrossRef]
    • (2015) Sci. Transl. Med. , vol.7 , pp. 301ra132
    • Muthumani, K.1    Falzarano, D.2    Reuschel, E.L.3    Tingey, C.4    Flingai, S.5    Villarreal, D.O.6    Wise, M.7    Patel, A.8    Izmirly, A.9    Aljuaid, A.10
  • 23
    • 84886937421 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virus-neutralizing antibodies
    • Song, F.; Fux, R.; Provacia, L.B.; Volz, A.; Eickmann, M.; Becker, S.; Osterhaus, A.D.; Haagmans, B.L.; Sutter, G. Middle East respiratory syndrome coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virus-neutralizing antibodies. J. Virol. 2013, 87, 11950–11954. [CrossRef] [PubMed]
    • (2013) J. Virol. , vol.87 , pp. 11950-11954
    • Song, F.1    Fux, R.2    Provacia, L.B.3    Volz, A.4    Eickmann, M.5    Becker, S.6    Osterhaus, A.D.7    Haagmans, B.L.8    Sutter, G.9
  • 24
    • 84938151524 scopus 로고    scopus 로고
    • Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein
    • Volz, A.; Kupke, A.; Song, F.; Jany, S.; Fux, R.; Shams-Eldin, H.; Schmidt, J.; Becker, C.; Eickmann, M.; Becker, S.; et al. Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein. J. Virol. 2015, 89, 8651–8656. [CrossRef]
    • (2015) J. Virol. , vol.89 , pp. 8651-8656
    • Volz, A.1    Kupke, A.2    Song, F.3    Jany, S.4    Fux, R.5    Shams-Eldin, H.6    Schmidt, J.7    Becker, C.8    Eickmann, M.9    Becker, S.10
  • 26
    • 3142679423 scopus 로고    scopus 로고
    • Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in sars patients by enzyme-linked immunosorbent assay
    • Lau, S.K.; Woo, P.C.; Wong, B.H.; Tsoi, H.W.; Woo, G.K.; Poon, R.W.; Chan, K.H.; Wei, W.I.; Peiris, J.S.; Yuen, K.Y. Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in sars patients by enzyme-linked immunosorbent assay. J. Clin. Microbiol. 2004, 42, 2884–2889. [CrossRef] [PubMed]
    • (2004) J. Clin. Microbiol. , vol.42 , pp. 2884-2889
    • Lau, S.K.1    Woo, P.C.2    Wong, B.H.3    Tsoi, H.W.4    Woo, G.K.5    Poon, R.W.6    Chan, K.H.7    Wei, W.I.8    Peiris, J.S.9    Yuen, K.Y.10
  • 27
    • 2442511729 scopus 로고    scopus 로고
    • Cloning, sequencing, expression, and purification of SARS-associated coronavirus nucleocapsid protein for serodiagnosis of SARS
    • Timani, K.A.; Ye, L.; Ye, L.; Zhu, Y.; Wu, Z.; Gong, Z. Cloning, sequencing, expression, and purification of SARS-associated coronavirus nucleocapsid protein for serodiagnosis of SARS. J. Clin. Virol. 2004, 30, 309–312. [CrossRef] [PubMed]
    • (2004) J. Clin. Virol. , vol.30 , pp. 309-312
    • Timani, K.A.1    Ye, L.2    Ye, L.3    Zhu, Y.4    Wu, Z.5    Gong, Z.6
  • 29
    • 18944399219 scopus 로고    scopus 로고
    • Characterization of monoclonal antibody against SARS coronavirus nucleocapsid antigen and development of an antigen capture ELISA
    • He, Q.; Du, Q.; Lau, S.; Manopo, I.; Lu, L.; Chan, S.W.; Fenner, B.J.; Kwang, J. Characterization of monoclonal antibody against SARS coronavirus nucleocapsid antigen and development of an antigen capture ELISA. J. Virol. Methods 2005, 127, 46–53. [CrossRef]
    • (2005) J. Virol. Methods , vol.127 , pp. 46-53
    • He, Q.1    Du, Q.2    Lau, S.3    Manopo, I.4    Lu, L.5    Chan, S.W.6    Fenner, B.J.7    Kwang, J.8
  • 30
    • 84966393702 scopus 로고    scopus 로고
    • Development of Monoclonal Antibody and Diagnostic Test for Middle East Respiratory Syndrome Coronavirus Using Cell-Free Synthesized Nucleocapsid Antigen
    • Yamaoka, Y.; Matsuyama, S.; Fukushi, S.; Matsunaga, S.; Matsushima, Y.; Kuroyama, H.; Kimura, H.; Takeda, M.; Chimuro, T.; Ryo, A. Development of Monoclonal Antibody and Diagnostic Test for Middle East Respiratory Syndrome Coronavirus Using Cell-Free Synthesized Nucleocapsid Antigen. Front. Microbiol. 2016, 7, 509. [CrossRef]
    • (2016) Front. Microbiol. , vol.7 , pp. 509
    • Yamaoka, Y.1    Matsuyama, S.2    Fukushi, S.3    Matsunaga, S.4    Matsushima, Y.5    Kuroyama, H.6    Kimura, H.7    Takeda, M.8    Chimuro, T.9    Ryo, A.10
  • 31
    • 84905901545 scopus 로고    scopus 로고
    • The coronavirus nucleocapsid is a multifunctional protein
    • McBride, R.; van Zyl, M.; Fielding, B.C. The coronavirus nucleocapsid is a multifunctional protein. Viruses 2014, 6, 2991–3018. [CrossRef]
    • (2014) Viruses , vol.6 , pp. 2991-3018
    • McBride, R.1    van Zyl, M.2    Fielding, B.C.3
  • 32
    • 85047405559 scopus 로고    scopus 로고
    • Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus
    • Hsin, W.-C.; Chang, C.-H.; Chang, C.-Y.; Peng, W.-H.; Chien, C.-L.; Chang, M.-F.; Chang, S.C. Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus. J. Biomed. Sci. 2018, 25, 47. [CrossRef] [PubMed]
    • (2018) J. Biomed. Sci. , vol.25 , pp. 47
    • Hsin, W.-C.1    Chang, C.-H.2    Chang, C.-Y.3    Peng, W.-H.4    Chien, C.-L.5    Chang, M.-F.6    Chang, S.C.7
  • 33
    • 7644242097 scopus 로고    scopus 로고
    • The nucleoprotein is required for efficient coronavirus genome replication
    • Almazan, F.; Galan, C.; Enjuanes, L. The nucleoprotein is required for efficient coronavirus genome replication. J. Virol. 2004, 78, 12683–12688. [CrossRef] [PubMed]
    • (2004) J. Virol. , vol.78 , pp. 12683-12688
    • Almazan, F.1    Galan, C.2    Enjuanes, L.3
  • 34
    • 75449101470 scopus 로고    scopus 로고
    • Coronavirus nucleocapsid protein facilitates template switching and is required for efficient transcription
    • Zuniga, S.; Cruz, J.L.; Sola, I.; Mateos-Gomez, P.A.; Palacio, L.; Enjuanes, L. Coronavirus nucleocapsid protein facilitates template switching and is required for efficient transcription. J. Virol. 2010, 84, 2169–2175. [CrossRef]
    • (2010) J. Virol. , vol.84 , pp. 2169-2175
    • Zuniga, S.1    Cruz, J.L.2    Sola, I.3    Mateos-Gomez, P.A.4    Palacio, L.5    Enjuanes, L.6
  • 35
    • 13444260839 scopus 로고    scopus 로고
    • Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3
    • Spiegel, M.; Pichlmair, A.; Martinez-Sobrido, L.; Cros, J.; Garcia-Sastre, A.; Haller, O.; Weber, F. Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3. J. Virol. 2005, 79, 2079–2086. [CrossRef] [PubMed]
    • (2005) J. Virol. , vol.79 , pp. 2079-2086
    • Spiegel, M.1    Pichlmair, A.2    Martinez-Sobrido, L.3    Cros, J.4    Garcia-Sastre, A.5    Haller, O.6    Weber, F.7
  • 36
    • 33846104528 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists
    • Kopecky-Bromberg, S.A.; Martinez-Sobrido, L.; Frieman, M.; Baric, R.A.; Palese, P. Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists. J. Virol. 2007, 81, 548–557. [CrossRef] [PubMed]
    • (2007) J. Virol. , vol.81 , pp. 548-557
    • Kopecky-Bromberg, S.A.1    Martinez-Sobrido, L.2    Frieman, M.3    Baric, R.A.4    Palese, P.5
  • 37
    • 79960315021 scopus 로고    scopus 로고
    • SARS-CoV nucleocapsid protein antagonizes IFN-beta response by targeting initial step of IFN-beta induction pathway, and its C-terminal region is critical for the antagonism
    • Lu, X.; Pan, J.; Tao, J.; Guo, D. SARS-CoV nucleocapsid protein antagonizes IFN-beta response by targeting initial step of IFN-beta induction pathway, and its C-terminal region is critical for the antagonism. Virus Genes 2011, 42, 37–45. [CrossRef] [PubMed]
    • (2011) Virus Genes , vol.42 , pp. 37-45
    • Lu, X.1    Pan, J.2    Tao, J.3    Guo, D.4
  • 38
    • 85055073935 scopus 로고    scopus 로고
    • Overexpression of the nucleocapsid protein of Middle East respiratory syndrome coronavirus up-regulates CXCL10
    • Aboagye, J.O.; Yew, C.W.; Ng, O.W.; Monteil, V.M.; Mirazimi, A.; Tan, Y.J. Overexpression of the nucleocapsid protein of Middle East respiratory syndrome coronavirus up-regulates CXCL10. Biosci. Rep. 2018, 38, BSR20181059. [CrossRef]
    • (2018) Biosci. Rep. , vol.38
    • Aboagye, J.O.1    Yew, C.W.2    Ng, O.W.3    Monteil, V.M.4    Mirazimi, A.5    Tan, Y.J.6
  • 39
    • 79959535550 scopus 로고    scopus 로고
    • Lack of peripheral memory B cell responses in recovered patients with severe acute respiratory syndrome: A six-year follow-up study
    • Tang, F.; Quan, Y.; Xin, Z.T.; Wrammert, J.; Ma, M.J.; Lv, H.; Wang, T.B.; Yang, H.; Richardus, J.H.; Liu, W.; et al. Lack of peripheral memory B cell responses in recovered patients with severe acute respiratory syndrome: A six-year follow-up study. J. Immunol. 2011, 186, 7264–7268. [CrossRef]
    • (2011) J. Immunol. , vol.186 , pp. 7264-7268
    • Tang, F.1    Quan, Y.2    Xin, Z.T.3    Wrammert, J.4    Ma, M.J.5    Lv, H.6    Wang, T.B.7    Yang, H.8    Richardus, J.H.9    Liu, W.10
  • 40
    • 85016333549 scopus 로고    scopus 로고
    • DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice
    • Chi, H.; Zheng, X.; Wang, X.; Wang, C.; Wang, H.; Gai, W.; Perlman, S.; Yang, S.; Zhao, J.; Xia, X. DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice. Vaccine 2017, 35, 2069–2075. [CrossRef]
    • (2017) Vaccine , vol.35 , pp. 2069-2075
    • Chi, H.1    Zheng, X.2    Wang, X.3    Wang, C.4    Wang, H.5    Gai, W.6    Perlman, S.7    Yang, S.8    Zhao, J.9    Xia, X.10
  • 42
    • 85046705063 scopus 로고    scopus 로고
    • Heterologous prime-boost vaccination with adenoviral vector and protein nanoparticles induces both Th1 and Th2 responses against Middle East respiratory syndrome coronavirus
    • [CrossRef] [PubMed]
    • Jung, S.Y.; Kang, K.W.; Lee, E.Y.; Seo, D.W.; Kim, H.L.; Kim, H.; Kwon, T.; Park, H.L.; Kim, H.; Lee, S.M.; et al. Heterologous prime-boost vaccination with adenoviral vector and protein nanoparticles induces both Th1 and Th2 responses against Middle East respiratory syndrome coronavirus. Vaccine 2018, 36, 3468–3476. [CrossRef] [PubMed]
    • (2018) Vaccine , vol.36 , pp. 3468-3476
    • Jung, S.Y.1    Kang, K.W.2    Lee, E.Y.3    Seo, D.W.4    Kim, H.L.5    Kim, H.6    Kwon, T.7    Park, H.L.8    Kim, H.9    Lee, S.M.10
  • 43
    • 85014640544 scopus 로고    scopus 로고
    • Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC
    • Liu, W.J.; Lan, J.; Liu, K.; Deng, Y.; Yao, Y.; Wu, S.; Chen, H.; Bao, L.; Zhang, H.; Zhao, M.; et al. Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol. 2017, 198, 873–882. [CrossRef] [PubMed]
    • (2017) J. Immunol. , vol.198 , pp. 873-882
    • Liu, W.J.1    Lan, J.2    Liu, K.3    Deng, Y.4    Yao, Y.5    Wu, S.6    Chen, H.7    Bao, L.8    Zhang, H.9    Zhao, M.10
  • 45
    • 84866785687 scopus 로고    scopus 로고
    • Easy and efficient protocols for working with recombinant vaccinia virus MVA
    • Kremer, M.; Volz, A.; Kreijtz, J.H.; Fux, R.; Lehmann, M.H.; Sutter, G. Easy and efficient protocols for working with recombinant vaccinia virus MVA. Methods Mol. Biol. 2012, 890, 59–92. [CrossRef]
    • (2012) Methods Mol. Biol. , vol.890 , pp. 59-92
    • Kremer, M.1    Volz, A.2    Kreijtz, J.H.3    Fux, R.4    Lehmann, M.H.5    Sutter, G.6
  • 46
    • 0030446387 scopus 로고    scopus 로고
    • Development of a replication-deficient recombinant vaccinia virus vaccine effective against parainfluenza virus 3 infection in an animal model
    • Wyatt, L.S.; Shors, S.T.; Murphy, B.R.; Moss, B. Development of a replication-deficient recombinant vaccinia virus vaccine effective against parainfluenza virus 3 infection in an animal model. Vaccine 1996, 14, 1451–1458. [CrossRef]
    • (1996) Vaccine , vol.14 , pp. 1451-1458
    • Wyatt, L.S.1    Shors, S.T.2    Murphy, B.R.3    Moss, B.4
  • 47
    • 84959432907 scopus 로고    scopus 로고
    • Pooled-Peptide Epitope Mapping Strategies Are Efficient and Highly Sensitive: An Evaluation of Methods for Identifying Human T Cell Epitope Specificities in Large-Scale HIV Vaccine Efficacy Trials
    • Fiore-Gartland, A.; Manso, B.A.; Friedrich, D.P.; Gabriel, E.E.; Finak, G.; Moodie, Z.; Hertz, T.; De Rosa, S.C.; Frahm, N.; Gilbert, P.B.; et al. Pooled-Peptide Epitope Mapping Strategies Are Efficient and Highly Sensitive: An Evaluation of Methods for Identifying Human T Cell Epitope Specificities in Large-Scale HIV Vaccine Efficacy Trials. PLoS ONE 2016, 11, e0147812. [CrossRef] [PubMed]
    • (2016) Plos ONE , vol.11
    • Fiore-Gartland, A.1    Manso, B.A.2    Friedrich, D.P.3    Gabriel, E.E.4    Finak, G.5    Moodie, Z.6    Hertz, T.7    de Rosa, S.C.8    Frahm, N.9    Gilbert, P.B.10
  • 48
    • 84996939009 scopus 로고    scopus 로고
    • Norovirus-Specific Memory T Cell Responses in Adult Human Donors
    • Malm, M.; Tamminen, K.; Vesikari, T.; Blazevic, V. Norovirus-Specific Memory T Cell Responses in Adult Human Donors. Front. Microbiol. 2016, 7, 1570. [CrossRef]
    • (2016) Front. Microbiol. , vol.7 , pp. 1570
    • Malm, M.1    Tamminen, K.2    Vesikari, T.3    Blazevic, V.4
  • 50
    • 84877339392 scopus 로고    scopus 로고
    • The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies
    • Gierer, S.; Bertram, S.; Kaup, F.; Wrensch, F.; Heurich, A.; Kramer-Kuhl, A.; Welsch, K.; Winkler, M.; Meyer, B.; Drosten, C.; et al. The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies. J. Virol. 2013, 87, 5502–5511. [CrossRef]
    • (2013) J. Virol. , vol.87 , pp. 5502-5511
    • Gierer, S.1    Bertram, S.2    Kaup, F.3    Wrensch, F.4    Heurich, A.5    Kramer-Kuhl, A.6    Welsch, K.7    Winkler, M.8    Meyer, B.9    Drosten, C.10
  • 51
    • 84908065761 scopus 로고    scopus 로고
    • Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein
    • Millet, J.K.; Whittaker, G.R. Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein. Proc. Natl. Acad. Sci. USA 2014, 111, 15214–15219. [CrossRef]
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 15214-15219
    • Millet, J.K.1    Whittaker, G.R.2
  • 54
    • 84999816148 scopus 로고    scopus 로고
    • The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection
    • Jiaming, L.; Yanfeng, Y.; Yao, D.; Yawei, H.; Linlin, B.; Baoying, H.; Jinghua, Y.; Gao, G.F.; Chuan, Q.; Wenjie, T. The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Vaccine 2017, 35, 10–18. [CrossRef] [PubMed]
    • (2017) Vaccine , vol.35 , pp. 10-18
    • Jiaming, L.1    Yanfeng, Y.2    Yao, D.3    Yawei, H.4    Linlin, B.5    Baoying, H.6    Jinghua, Y.7    Gao, G.F.8    Chuan, Q.9    Wenjie, T.10
  • 55
    • 0033899980 scopus 로고    scopus 로고
    • Characterization of the coronavirus M protein and nucleocapsid interaction in infected cells
    • Narayanan, K.; Maeda, A.; Maeda, J.; Makino, S. Characterization of the coronavirus M protein and nucleocapsid interaction in infected cells. J. Virol. 2000, 74, 8127–8134. [CrossRef] [PubMed]
    • (2000) J. Virol. , vol.74 , pp. 8127-8134
    • Narayanan, K.1    Maeda, A.2    Maeda, J.3    Makino, S.4
  • 56
    • 9944256109 scopus 로고    scopus 로고
    • Immune responses against SARS-coronavirus nucleocapsid protein induced by DNA vaccine
    • Zhao, P.; Cao, J.; Zhao, L.J.; Qin, Z.L.; Ke, J.S.; Pan, W.; Ren, H.; Yu, J.G.; Qi, Z.T. Immune responses against SARS-coronavirus nucleocapsid protein induced by DNA vaccine. Virology 2005, 331, 128–135. [CrossRef] [PubMed]
    • (2005) Virology , vol.331 , pp. 128-135
    • Zhao, P.1    Cao, J.2    Zhao, L.J.3    Qin, Z.L.4    Ke, J.S.5    Pan, W.6    Ren, H.7    Yu, J.G.8    Qi, Z.T.9
  • 58
    • 77956038851 scopus 로고    scopus 로고
    • T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice
    • Zhao, J.; Zhao, J.; Perlman, S. T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice. J. Virol. 2010, 84, 9318–9325. [CrossRef]
    • (2010) J. Virol. , vol.84 , pp. 9318-9325
    • Zhao, J.1    Zhao, J.2    Perlman, S.3
  • 61
    • 85042708477 scopus 로고    scopus 로고
    • Induction and Subversion of Human Protective Immunity: Contrasting Influenza and Respiratory Syncytial Virus
    • [CrossRef]
    • Ascough, S.; Paterson, S.; Chiu, C. Induction and Subversion of Human Protective Immunity: Contrasting Influenza and Respiratory Syncytial Virus. Front. Immunol. 2018, 9, 323. [CrossRef]
    • (2018) Front. Immunol , vol.9 , pp. 323
    • Ascough, S.1    Paterson, S.2    Chiu, C.3
  • 64
    • 85008888694 scopus 로고    scopus 로고
    • Structural characterization of the N-terminal part of the MERS-CoV nucleocapsid by X-ray diffraction and small-angle X-ray scattering
    • Papageorgiou, N.; Lichiere, J.; Baklouti, A.; Ferron, F.; Sevajol, M.; Canard, B.; Coutard, B. Structural characterization of the N-terminal part of the MERS-CoV nucleocapsid by X-ray diffraction and small-angle X-ray scattering. Acta Crystallogr. Sect. D Struct. Biol. 2016, 72, 192–202. [CrossRef]
    • (2016) Acta Crystallogr. Sect. D Struct. Biol. , vol.72 , pp. 192-202
    • Papageorgiou, N.1    Lichiere, J.2    Baklouti, A.3    Ferron, F.4    Sevajol, M.5    Canard, B.6    Coutard, B.7
  • 65
    • 85023597584 scopus 로고    scopus 로고
    • The clinical and virological features of the first imported case causing MERS-CoV outbreak in South Korea, 2015
    • Lee, J.Y.; Kim, Y.J.; Chung, E.H.; Kim, D.W.; Jeong, I.; Kim, Y.; Yun, M.R.; Kim, S.S.; Kim, G.; Joh, J.S. The clinical and virological features of the first imported case causing MERS-CoV outbreak in South Korea, 2015. BMC Infect. Dis. 2017, 17, 498. [CrossRef] [PubMed]
    • (2017) BMC Infect. Dis. , vol.17 , pp. 498
    • Lee, J.Y.1    Kim, Y.J.2    Chung, E.H.3    Kim, D.W.4    Jeong, I.5    Kim, Y.6    Yun, M.R.7    Kim, S.S.8    Kim, G.9    Joh, J.S.10
  • 68
    • 84911383558 scopus 로고    scopus 로고
    • Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness
    • Sui, J.; Deming, M.; Rockx, B.; Liddington, R.C.; Zhu, Q.K.; Baric, R.S.; Marasco, W.A. Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness. J. Virol. 2014, 88, 13769–13780. [CrossRef]
    • (2014) J. Virol. , vol.88 , pp. 13769-13780
    • Sui, J.1    Deming, M.2    Rockx, B.3    Liddington, R.C.4    Zhu, Q.K.5    Baric, R.S.6    Marasco, W.A.7
  • 69
    • 85008214652 scopus 로고    scopus 로고
    • Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants
    • Tai, W.; Wang, Y.; Fett, C.A.; Zhao, G.; Li, F.; Perlman, S.; Jiang, S.; Zhou, Y.; Du, L. Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants. J. Virol. 2017, 91, e01651-16. [CrossRef]
    • (2017) J. Virol , vol.91 , pp. e01651
    • Tai, W.1    Wang, Y.2    Fett, C.A.3    Zhao, G.4    Li, F.5    Perlman, S.6    Jiang, S.7    Zhou, Y.8    Du, L.9


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