메뉴 건너뛰기




Volumn 1865, Issue 2, 2019, Pages 391-402

CXCR6 protects from inflammation and fibrosis in NEMOLPC-KO mice

Author keywords

Chemokine receptor; Hepatocytes; Inflammation; Liver fibrosis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CD69 ANTIGEN; CHEMOKINE RECEPTOR CXCR6; COLLAGEN; CYCLINE; FAS LIGAND; GAMMA INTERFERON; GLUTAMATE DEHYDROGENASE; HYDROXYPROLINE; INTERLEUKIN 4; LACTATE DEHYDROGENASE; LACTIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; CYTOCHROME P450 4A; NEMO PROTEIN, MOUSE; SIGNAL PEPTIDE;

EID: 85057256259     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2018.11.020     Document Type: Article
Times cited : (18)

References (31)
  • 1
    • 33846839443 scopus 로고    scopus 로고
    • Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
    • Luedde, T., et al. Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 11 (2007), 119–132, 10.1016/j.ccr.2006.12.016.
    • (2007) Cancer Cell , vol.11 , pp. 119-132
    • Luedde, T.1
  • 3
    • 77952107213 scopus 로고    scopus 로고
    • TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer
    • Bettermann, K., et al. TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. Cancer Cell 17 (2010), 481–496, 10.1016/j.ccr.2010.03.021.
    • (2010) Cancer Cell , vol.17 , pp. 481-496
    • Bettermann, K.1
  • 4
    • 84919465499 scopus 로고    scopus 로고
    • Cell death and cell death responses in liver disease: mechanisms and clinical relevance
    • e764
    • Luedde, T., Kaplowitz, N., Schwabe, R.F., Cell death and cell death responses in liver disease: mechanisms and clinical relevance. Gastroenterology 147 (2014), 765–783 e764 https://doi.org/10.1053/j.gastro.2014.07.018.
    • (2014) Gastroenterology , vol.147 , pp. 765-783
    • Luedde, T.1    Kaplowitz, N.2    Schwabe, R.F.3
  • 5
    • 84877794003 scopus 로고    scopus 로고
    • Chemokine receptor CXCR6-dependent hepatic NK T cell accumulation promotes inflammation and liver fibrosis
    • Wehr, A., et al. Chemokine receptor CXCR6-dependent hepatic NK T cell accumulation promotes inflammation and liver fibrosis. J. Immunol. 190 (2013), 5226–5236, 10.4049/jimmunol.1202909.
    • (2013) J. Immunol. , vol.190 , pp. 5226-5236
    • Wehr, A.1
  • 6
    • 19344371631 scopus 로고    scopus 로고
    • Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids
    • Geissmann, F., et al. Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids. PLoS Biol., 3, 2005, e113, 10.1371/journal.pbio.0030113.
    • (2005) PLoS Biol. , vol.3
    • Geissmann, F.1
  • 7
    • 85057273809 scopus 로고    scopus 로고
    • The roles of CXCL16 and CXCR6 in liver inflammation and fibrosis
    • Wehr, A., Tacke, F., The roles of CXCL16 and CXCR6 in liver inflammation and fibrosis. Curr. Pathobiol. Rep. 3 (2015), 283–290, 10.1007/s40139-015-0090-2.
    • (2015) Curr. Pathobiol. Rep. , vol.3 , pp. 283-290
    • Wehr, A.1    Tacke, F.2
  • 8
    • 84939292424 scopus 로고    scopus 로고
    • Long term intravital multiphoton microscopy imaging of immune cells in healthy and diseased liver using CXCR6.Gfp reporter mice
    • Heymann, F., et al. Long term intravital multiphoton microscopy imaging of immune cells in healthy and diseased liver using CXCR6.Gfp reporter mice. J. Vis. Exp., 2015, 10.3791/52607.
    • (2015) J. Vis. Exp.
    • Heymann, F.1
  • 9
    • 85049305039 scopus 로고    scopus 로고
    • Activation of the CXCL16/CXCR6 pathway promotes lipid deposition in fatty livers of apolipoprotein E knockout mice and HepG2 cells
    • Ma, K.L., et al. Activation of the CXCL16/CXCR6 pathway promotes lipid deposition in fatty livers of apolipoprotein E knockout mice and HepG2 cells. Am. J. Transl. Res. 10 (2018), 1802–1816.
    • (2018) Am. J. Transl. Res. , vol.10 , pp. 1802-1816
    • Ma, K.L.1
  • 10
    • 85028347686 scopus 로고    scopus 로고
    • Hepatic CXCL16 is increased in gallstone accompanied with liver injury
    • Zhang, S., et al. Hepatic CXCL16 is increased in gallstone accompanied with liver injury. Eur. J. Clin. Investig. 47 (2017), 667–674, 10.1111/eci.12788.
    • (2017) Eur. J. Clin. Investig. , vol.47 , pp. 667-674
    • Zhang, S.1
  • 11
    • 85054897181 scopus 로고    scopus 로고
    • CXC motif ligand 16 promotes nonalcoholic fatty liver disease progression via hepatocyte-stellate cell crosstalk
    • Jiang, L., et al. CXC motif ligand 16 promotes nonalcoholic fatty liver disease progression via hepatocyte-stellate cell crosstalk. J. Clin. Endocrinol. Metab. 103 (2018), 3974–3985, 10.1210/jc.2018-00762.
    • (2018) J. Clin. Endocrinol. Metab. , vol.103 , pp. 3974-3985
    • Jiang, L.1
  • 12
    • 84910020145 scopus 로고    scopus 로고
    • Pharmacological inhibition of the chemokine CXCL16 diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury
    • Wehr, A., et al. Pharmacological inhibition of the chemokine CXCL16 diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury. PLoS One, 9, 2014, e112327, 10.1371/journal.pone.0112327.
    • (2014) PLoS One , vol.9
    • Wehr, A.1
  • 13
    • 0034665330 scopus 로고    scopus 로고
    • The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse
    • Unutmaz, D., et al. The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse. J. Immunol. 165 (2000), 3284–3292.
    • (2000) J. Immunol. , vol.165 , pp. 3284-3292
    • Unutmaz, D.1
  • 14
    • 67651174837 scopus 로고    scopus 로고
    • Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis
    • Karlmark, K.R., et al. Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis. Hepatology 50 (2009), 261–274, 10.1002/hep.22950.
    • (2009) Hepatology , vol.50 , pp. 261-274
    • Karlmark, K.R.1
  • 15
    • 85009126405 scopus 로고    scopus 로고
    • RIPK1 suppresses a TRAF2-dependent pathway to liver cancer
    • Schneider, A.T., et al. RIPK1 suppresses a TRAF2-dependent pathway to liver cancer. Cancer Cell 31 (2017), 94–109, 10.1016/j.ccell.2016.11.009.
    • (2017) Cancer Cell , vol.31 , pp. 94-109
    • Schneider, A.T.1
  • 16
    • 84857444883 scopus 로고    scopus 로고
    • Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice
    • Heymann, F., et al. Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice. Hepatology 55 (2012), 898–909, 10.1002/hep.24764.
    • (2012) Hepatology , vol.55 , pp. 898-909
    • Heymann, F.1
  • 17
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry, R.A., et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4 (2003), 249–264, 10.1093/biostatistics/4.2.249.
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1
  • 18
    • 84943388769 scopus 로고    scopus 로고
    • oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on bioconductor
    • Loffler-Wirth, H., Kalcher, M., Binder, H., oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on bioconductor. Bioinformatics 31 (2015), 3225–3227, 10.1093/bioinformatics/btv342.
    • (2015) Bioinformatics , vol.31 , pp. 3225-3227
    • Loffler-Wirth, H.1    Kalcher, M.2    Binder, H.3
  • 19
    • 79960662814 scopus 로고    scopus 로고
    • Expression cartography of human tissues using self organizing maps
    • Wirth, H., Loffler, M., von Bergen, M., Binder, H., Expression cartography of human tissues using self organizing maps. BMC Bioinf., 12, 2011, 306, 10.1186/1471-2105-12-306.
    • (2011) BMC Bioinf. , vol.12 , pp. 306
    • Wirth, H.1    Loffler, M.2    von Bergen, M.3    Binder, H.4
  • 20
    • 85016145766 scopus 로고    scopus 로고
    • PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements
    • Mi, H., et al. PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements. Nucleic Acids Res. 45 (2017), D183–D189, 10.1093/nar/gkw1138.
    • (2017) Nucleic Acids Res. , vol.45 , pp. D183-D189
    • Mi, H.1
  • 21
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: a software environment for integrated models of biomolecular interaction networks
    • Shannon, P., et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 13 (2003), 2498–2504, 10.1101/gr.1239303.
    • (2003) Genome Res. , vol.13 , pp. 2498-2504
    • Shannon, P.1
  • 22
    • 24044440971 scopus 로고    scopus 로고
    • BiNGO: a cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks
    • Maere, S., Heymans, K., Kuiper, M., BiNGO: a cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics 21 (2005), 3448–3449, 10.1093/bioinformatics/bti551.
    • (2005) Bioinformatics , vol.21 , pp. 3448-3449
    • Maere, S.1    Heymans, K.2    Kuiper, M.3
  • 23
    • 78649775562 scopus 로고    scopus 로고
    • Enrichment map: a network-based method for gene-set enrichment visualization and interpretation
    • Merico, D., Isserlin, R., Stueker, O., Emili, A., Bader, G.D., Enrichment map: a network-based method for gene-set enrichment visualization and interpretation. PLoS One, 5, 2010, e13984, 10.1371/journal.pone.0013984.
    • (2010) PLoS One , vol.5
    • Merico, D.1    Isserlin, R.2    Stueker, O.3    Emili, A.4    Bader, G.D.5
  • 24
    • 84883296695 scopus 로고    scopus 로고
    • RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation
    • Vucur, M., et al. RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation. Cell Rep. 4 (2013), 776–790, 10.1016/j.celrep.2013.07.035.
    • (2013) Cell Rep. , vol.4 , pp. 776-790
    • Vucur, M.1
  • 25
    • 0037382797 scopus 로고    scopus 로고
    • c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration
    • Schwabe, R.F., et al. c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration. Hepatology 37 (2003), 824–832, 10.1053/jhep.2003.50135.
    • (2003) Hepatology , vol.37 , pp. 824-832
    • Schwabe, R.F.1
  • 26
    • 85021818299 scopus 로고    scopus 로고
    • CXCL16 deficiency attenuates acetaminophen-induced hepatotoxicity through decreasing hepatic oxidative stress and inflammation in mice
    • Wang, H., et al. CXCL16 deficiency attenuates acetaminophen-induced hepatotoxicity through decreasing hepatic oxidative stress and inflammation in mice. Acta Biochim. Biophys. Sin. 49 (2017), 541–549, 10.1093/abbs/gmx040.
    • (2017) Acta Biochim. Biophys. Sin. , vol.49 , pp. 541-549
    • Wang, H.1
  • 27
    • 85047415625 scopus 로고    scopus 로고
    • Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells
    • Ma, C., et al. Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Science, 360, 2018, 10.1126/science.aan5931.
    • (2018) Science , vol.360
    • Ma, C.1
  • 28
    • 11844294973 scopus 로고    scopus 로고
    • CXC chemokine ligand 16 promotes integrin-mediated adhesion of liver-infiltrating lymphocytes to cholangiocytes and hepatocytes within the inflamed human liver
    • Heydtmann, M., et al. CXC chemokine ligand 16 promotes integrin-mediated adhesion of liver-infiltrating lymphocytes to cholangiocytes and hepatocytes within the inflamed human liver. J. Immunol. 174 (2005), 1055–1062.
    • (2005) J. Immunol. , vol.174 , pp. 1055-1062
    • Heydtmann, M.1
  • 29
    • 79960797578 scopus 로고    scopus 로고
    • Redox balance in the pathogenesis of nonalcoholic fatty liver disease: mechanisms and therapeutic opportunities
    • Gambino, R., Musso, G., Cassader, M., Redox balance in the pathogenesis of nonalcoholic fatty liver disease: mechanisms and therapeutic opportunities. Antioxid. Redox Signal. 15 (2011), 1325–1365, 10.1089/ars.2009.3058.
    • (2011) Antioxid. Redox Signal. , vol.15 , pp. 1325-1365
    • Gambino, R.1    Musso, G.2    Cassader, M.3
  • 30
    • 84921626636 scopus 로고    scopus 로고
    • Inhibition of CYP4A reduces hepatic endoplasmic reticulum stress and features of diabetes in mice
    • Park, E.C., et al. Inhibition of CYP4A reduces hepatic endoplasmic reticulum stress and features of diabetes in mice. Gastroenterology 147 (2014), 860–869, 10.1053/j.gastro.2014.06.039.
    • (2014) Gastroenterology , vol.147 , pp. 860-869
    • Park, E.C.1
  • 31
    • 85016099805 scopus 로고    scopus 로고
    • Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis
    • Zhang, X., et al. Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis. Proc. Natl. Acad. Sci. U. S. A. 114 (2017), 3181–3185, 10.1073/pnas.1700172114.
    • (2017) Proc. Natl. Acad. Sci. U. S. A. , vol.114 , pp. 3181-3185
    • Zhang, X.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.