메뉴 건너뛰기




Volumn 9, Issue 1, 2018, Pages

Short-chain ketone production by engineered polyketide synthases in Streptomyces albus

(16)  Yuzawa, Satoshi a,b,j   Mirsiaghi, Mona a   Jocic, Renee a   Fujii, Tatsuya b,c   Masson, Fabrice a   Benites, Veronica T a,b   Baidoo, Edward E K a,b   Sundstrom, Eric a   Tanjore, Deepti a   Pray, Todd R a   George, Anthe b,d   Davis, Ryan W d   Gladden, John M b,d   Simmons, Blake A a,b   Katz, Leonard b,e   Keasling, Jay D a,b,e,f,g,h,i  


Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; GASOLINE; KETONE; OCTANE; POLYKETIDE SYNTHASE;

EID: 85055910851     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-07040-0     Document Type: Article
Times cited : (53)

References (35)
  • 2
    • 84907936590 scopus 로고    scopus 로고
    • Substantial improvements in methyl ketone production in E. coli and insights on the pathway from in vitro studies
    • COI: 1:CAS:528:DC%2BC2cXhs1WitbbM
    • Goh, E. B. et al. Substantial improvements in methyl ketone production in E. coli and insights on the pathway from in vitro studies. Metab. Eng. 26, 67–76 (2014)
    • (2014) Metab. Eng. , vol.26 , pp. 67-76
    • Goh, E.B.1
  • 3
    • 84879830902 scopus 로고    scopus 로고
    • Engineering of Ralstonia eutropha H16 for autotrophic and heterotrophic production of methyl ketones
    • COI: 1:CAS:528:DC%2BC3sXhtFWjsbnI
    • Muller, J. et al. Engineering of Ralstonia eutropha H16 for autotrophic and heterotrophic production of methyl ketones. Appl. Environ. Microbiol. 79, 4433–4439 (2013)
    • (2013) Appl. Environ. Microbiol. , vol.79 , pp. 4433-4439
    • Muller, J.1
  • 4
    • 85013200608 scopus 로고    scopus 로고
    • Expanding the product portfolio of fungal type I fatty acid synthases
    • COI: 1:CAS:528:DC%2BC2sXis1ymtLY%3D
    • Zhu, Z. et al. Expanding the product portfolio of fungal type I fatty acid synthases. Nat. Chem. Biol. 13, 360–362 (2017)
    • (2017) Nat. Chem. Biol. , vol.13 , pp. 360-362
    • Zhu, Z.1
  • 5
    • 85020547969 scopus 로고    scopus 로고
    • Engineering high-level production of fatty alcohols by Saccharomyces cerevisiae from lignocellulosic feedstocks
    • d’Espaux, L. et al. Engineering high-level production of fatty alcohols by Saccharomyces cerevisiae from lignocellulosic feedstocks. Metab. Eng. 42, 115–125 (2017)
    • (2017) Metab. Eng. , vol.42 , pp. 115-125
    • d’Espaux, L.1
  • 6
    • 84928726177 scopus 로고    scopus 로고
    • Development of an orthogonal fatty acid biosynthesis system in E. coli for oleochemical production
    • COI: 1:CAS:528:DC%2BC2MXmslGis7o%3D
    • Haushalter, R. W. et al. Development of an orthogonal fatty acid biosynthesis system in E. coli for oleochemical production. Metab. Eng. 30, 1–6 (2015)
    • (2015) Metab. Eng. , vol.30 , pp. 1-6
    • Haushalter, R.W.1
  • 7
    • 38049001166 scopus 로고    scopus 로고
    • Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
    • COI: 1:CAS:528:DC%2BD1cXhtlSltQ%3D%3D
    • Atsumi, S., Hanai, T. & Liao, J. C. Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature 451, 86–89 (2008)
    • (2008) Nature , vol.451 , pp. 86-89
    • Atsumi, S.1    Hanai, T.2    Liao, J.C.3
  • 8
    • 84885166683 scopus 로고    scopus 로고
    • Engineering a synthetic pathway in cyanobacteria for isopropanol production directly from carbon dioxide and light
    • COI: 1:CAS:528:DC%2BC3sXhvFylu7rN
    • Kusakabe, T. et al. Engineering a synthetic pathway in cyanobacteria for isopropanol production directly from carbon dioxide and light. Metab. Eng. 20, 101–108 (2013)
    • (2013) Metab. Eng. , vol.20 , pp. 101-108
    • Kusakabe, T.1
  • 9
    • 84948178435 scopus 로고    scopus 로고
    • Integrative genomic mining for enzyme function to enable engineering of a non-natural biosynthetic pathway
    • COI: 1:CAS:528:DC%2BC2MXhvFWlsbbP
    • Mak, W. S. et al. Integrative genomic mining for enzyme function to enable engineering of a non-natural biosynthetic pathway. Nat. Commun. 6, 10005 (2015)
    • (2015) Nat. Commun. , vol.6
    • Mak, W.S.1
  • 10
    • 80051941601 scopus 로고    scopus 로고
    • Engineered reversal of the beta-oxidation cycle for the synthesis of fuels and chemicals
    • COI: 1:CAS:528:DC%2BC3MXhtVOkurbN
    • Dellomonaco, C., Clomburg, J. M., Miller, E. N. & Gonzalez, R. Engineered reversal of the beta-oxidation cycle for the synthesis of fuels and chemicals. Nature 476, 355–359 (2011)
    • (2011) Nature , vol.476 , pp. 355-359
    • Dellomonaco, C.1    Clomburg, J.M.2    Miller, E.N.3    Gonzalez, R.4
  • 11
    • 84886948663 scopus 로고    scopus 로고
    • Microbial production of short-chain alkanes
    • COI: 1:CAS:528:DC%2BC3sXhsFaksr%2FK
    • Choi, Y. J. & Lee, S. Y. Microbial production of short-chain alkanes. Nature 502, 571–574 (2013)
    • (2013) Nature , vol.502 , pp. 571-574
    • Choi, Y.J.1    Lee, S.Y.2
  • 12
  • 13
    • 85042187561 scopus 로고    scopus 로고
    • Engineering 1-alkene biosynthesis and secretion by dynamic regulation in Yeast
    • &
    • Zhou, Y. J., Hu, Y., Zhu, Z., Siewers, V. & Nielsen, J. Engineering 1-alkene biosynthesis and secretion by dynamic regulation in Yeast. ACS Synth Biol. (2018). 10.1021/acssynbio.7b00338
    • (2018) ACS Synth Biol
    • Zhou, Y.J.1    Hu, Y.2    Zhu, Z.3    Siewers, V.4    Nielsen, J.5
  • 14
    • 85018349502 scopus 로고    scopus 로고
    • Selection criteria and screening of potential biomass-derived streams as fuel blendstocks for advanced spark-ignitionengines
    • McCormick, R. L. et al. Selection criteria and screening of potential biomass-derived streams as fuel blendstocks for advanced spark-ignitionengines. SAE Int J. Fuels Lubr. 10, 442–460 (2017)
    • (2017) SAE Int J. Fuels Lubr. , vol.10 , pp. 442-460
    • McCormick, R.L.1
  • 15
    • 84881663509 scopus 로고    scopus 로고
    • Metabolic engineering of 2-pentanone synthesis in Escherichia coli
    • COI: 1:CAS:528:DC%2BC3sXltVygtbY%3D
    • Lan, E. I., Dekishima, Y., Chuang, D. S. & Liao, J. C. Metabolic engineering of 2-pentanone synthesis in Escherichia coli. AIChE J. 59, 3167–3175 (2013)
    • (2013) AIChE J. , vol.59 , pp. 3167-3175
    • Lan, E.I.1    Dekishima, Y.2    Chuang, D.S.3    Liao, J.C.4
  • 16
    • 84965161332 scopus 로고    scopus 로고
    • Engineering Escherichia coli for microbial production of butanone
    • Srirangan, K. et al. Engineering Escherichia coli for microbial production of butanone. Appl. Environ. Microbiol. 82, 2574–2584 (2016)
    • (2016) Appl. Environ. Microbiol. , vol.82 , pp. 2574-2584
    • Srirangan, K.1
  • 17
    • 85012836622 scopus 로고    scopus 로고
    • Comprehensive in vitro analysis of acyltransferase domain exchanges in modular polyketide synthases and its application for short-chain ketone production
    • COI: 1:CAS:528:DC%2BC28XhtlOqu7%2FE
    • Yuzawa, S. et al. Comprehensive in vitro analysis of acyltransferase domain exchanges in modular polyketide synthases and its application for short-chain ketone production. ACS Synth. Biol. 6, 139–147 (2017)
    • (2017) ACS Synth. Biol. , vol.6 , pp. 139-147
    • Yuzawa, S.1
  • 19
    • 33744483762 scopus 로고    scopus 로고
    • Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin
    • COI: 1:CAS:528:DC%2BD28XlsVOiur0%3D
    • Bihlmaier, C. et al. Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin. Antimicrob. Agents Chemother. 50, 2113–2121 (2006)
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 2113-2121
    • Bihlmaier, C.1
  • 20
    • 85034642032 scopus 로고    scopus 로고
    • Heterologous gene expression of N-terminally truncated variants of LipPks1 suggests a functionally critical structural motif in the N-terminus of modular polyketide synthase
    • COI: 1:CAS:528:DC%2BC2sXhs1CqtLzF
    • Yuzawa, S. et al. Heterologous gene expression of N-terminally truncated variants of LipPks1 suggests a functionally critical structural motif in the N-terminus of modular polyketide synthase. Acs. Chem. Biol. 12, 2725–2729 (2017)
    • (2017) Acs. Chem. Biol. , vol.12 , pp. 2725-2729
    • Yuzawa, S.1
  • 21
    • 84939557642 scopus 로고    scopus 로고
    • Minimum information about a biosynthetic gene cluster
    • COI: 1:CAS:528:DC%2BC2MXhtlKntrjN
    • Medema, M. H. et al. Minimum information about a biosynthetic gene cluster. Nat. Chem. Biol. 11, 625–631 (2015)
    • (2015) Nat. Chem. Biol. , vol.11 , pp. 625-631
    • Medema, M.H.1
  • 22
    • 77956468890 scopus 로고    scopus 로고
    • Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters
    • COI: 1:CAS:528:DC%2BC3cXhtVSmtLnL
    • Baltz, R. H. Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters. J. Ind. Microbiol. Biotechnol. 37, 759–772 (2010)
    • (2010) J. Ind. Microbiol. Biotechnol. , vol.37 , pp. 759-772
    • Baltz, R.H.1
  • 23
    • 85012853915 scopus 로고    scopus 로고
    • Development of next generation synthetic biology tools for uUse in Streptomyces venezuelae
    • COI: 1:CAS:528:DC%2BC28XhsVOrt73K
    • Phelan, R. M. et al. Development of next generation synthetic biology tools for uUse in Streptomyces venezuelae. ACS Synth. Biol. 6, 159–166 (2017)
    • (2017) ACS Synth. Biol. , vol.6 , pp. 159-166
    • Phelan, R.M.1
  • 24
    • 84942910137 scopus 로고    scopus 로고
    • Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces
    • COI: 1:CAS:528:DC%2BC2MXhsV2lt73N
    • Bai, C. et al. Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces. Proc. Natl Acad. Sci. USA 112, 12181–12186 (2015)
    • (2015) Proc. Natl. Acad. Sci. U. S. A. , vol.112 , pp. 12181-12186
    • Bai, C.1
  • 25
    • 84893112499 scopus 로고    scopus 로고
    • Medium optimization of Streptomyces sp. 17944 for tirandamycin B production and isolation and structural elucidation of tirandamycins H, I and J
    • COI: 1:CAS:528:DC%2BC2cXht1yhtb8%3D
    • Rateb, M. E. et al. Medium optimization of Streptomyces sp. 17944 for tirandamycin B production and isolation and structural elucidation of tirandamycins H, I and J. J. Antibiot. (Tokyo) 67, 127–132 (2014)
    • (2014) J. Antibiot. (Tokyo) , vol.67 , pp. 127-132
    • Rateb, M.E.1
  • 26
    • 0028079724 scopus 로고
    • The mRNA for the 23S rRNA methylase encoded by the ermE gene of Saccharopolyspora erythraea is translated in the absence of a conventional ribosome-binding site
    • COI: 1:CAS:528:DyaK2MXitFKgtb8%3D
    • Bibb, M. J., White, J., Ward, J. M. & Janssen, G. R. The mRNA for the 23S rRNA methylase encoded by the ermE gene of Saccharopolyspora erythraea is translated in the absence of a conventional ribosome-binding site. Mol. Microbiol. 14, 533–545 (1994)
    • (1994) Mol. Microbiol. , vol.14 , pp. 533-545
    • Bibb, M.J.1    White, J.2    Ward, J.M.3    Janssen, G.R.4
  • 27
    • 84879833139 scopus 로고    scopus 로고
    • An engineered strong promoter for streptomycetes
    • COI: 1:CAS:528:DC%2BC3sXhtFWjsbbM
    • Wang, W. et al. An engineered strong promoter for streptomycetes. Appl. Environ. Microbiol. 79, 4484–4492 (2013)
    • (2013) Appl. Environ. Microbiol. , vol.79 , pp. 4484-4492
    • Wang, W.1
  • 28
    • 84878653692 scopus 로고    scopus 로고
    • Broad substrate specificity of the loading didomain of the lipomycin polyketide synthase
    • COI: 1:CAS:528:DC%2BC3sXnvVKmt7g%3D
    • Yuzawa, S., Eng, C. H., Katz, L. & Keasling, J. D. Broad substrate specificity of the loading didomain of the lipomycin polyketide synthase. Biochemistry 52, 3791–3793 (2013)
    • (2013) Biochemistry , vol.52 , pp. 3791-3793
    • Yuzawa, S.1    Eng, C.H.2    Katz, L.3    Keasling, J.D.4
  • 29
    • 84896821323 scopus 로고    scopus 로고
    • Enzyme analysis of the polyketide synthase leads to the discovery of a novel analog of the antibiotic alpha-lipomycin
    • COI: 1:CAS:528:DC%2BC2cXjt1Wmsrs%3D
    • Yuzawa, S., Eng, C. H., Katz, L. & Keasling, J. D. Enzyme analysis of the polyketide synthase leads to the discovery of a novel analog of the antibiotic alpha-lipomycin. J. Antibiot. (Tokyo) 67, 199–201 (2014)
    • (2014) J. Antibiot. (Tokyo) , vol.67 , pp. 199-201
    • Yuzawa, S.1    Eng, C.H.2    Katz, L.3    Keasling, J.D.4
  • 30
    • 33750557880 scopus 로고    scopus 로고
    • High-level production of amorpha-4,11-diene in a two-phase partitioning bioreactor of metabolically engineered Escherichia coli
    • COI: 1:CAS:528:DC%2BD28XhtFarsbvF
    • Newman, J. D. et al. High-level production of amorpha-4,11-diene in a two-phase partitioning bioreactor of metabolically engineered Escherichia coli. Biotechnol. Bioeng. 95, 684–691 (2006)
    • (2006) Biotechnol. Bioeng. , vol.95 , pp. 684-691
    • Newman, J.D.1
  • 31
    • 84961844661 scopus 로고    scopus 로고
    • Engineering Escherichia coli for conversion of glucose to medium-chain omega-hydroxy fatty acids and alpha,omega-dicarboxylic acids
    • COI: 1:CAS:528:DC%2BC2MXitVSksrjF
    • Bowen, C. H., Bonin, J., Kogler, A., Barba-Ostria, C. & Zhang, F. Engineering Escherichia coli for conversion of glucose to medium-chain omega-hydroxy fatty acids and alpha,omega-dicarboxylic acids. ACS Synth. Biol. 5, 200–206 (2016)
    • (2016) ACS Synth. Biol. , vol.5 , pp. 200-206
    • Bowen, C.H.1    Bonin, J.2    Kogler, A.3    Barba-Ostria, C.4    Zhang, F.5
  • 32
    • 85038360975 scopus 로고    scopus 로고
    • Microbial synthesis of medium-chain chemicals from renewables
    • COI: 1:CAS:528:DC%2BC2sXhvFCjurbL
    • Sarria, S., Kruyer, N. S. & Peralta-Yahya, P. Microbial synthesis of medium-chain chemicals from renewables. Nat. Biotechnol. 35, 1158–1166 (2017)
    • (2017) Nat. Biotechnol. , vol.35 , pp. 1158-1166
    • Sarria, S.1    Kruyer, N.S.2    Peralta-Yahya, P.3
  • 34
    • 77952299957 scopus 로고    scopus 로고
    • Prodigal: prokaryotic gene recognition and translation initiation site identification
    • Hyatt, D. et al. Prodigal: prokaryotic gene recognition and translation initiation site identification. BMC Bioinforma. 11, 119 (2010)
    • (2010) BMC Bioinforma. , vol.11
    • Hyatt, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.