Intranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza

Science Translational Medicine

Volumn 5, Issue 187, 2013, Pages

  Limberis, Maria P ^a   Adam, Virginie S ^a   Wong, Gary ^b,c   Gren, Jason ^b,c   Kobasa, Darwyn ^b,c   Ross, Ted M ^d,e   Kobinger, Gary P ^b,c   Tretiakova, Anna ^a   Wilson, James M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANTIBODY ISOLATION; ARTICLE; CONTROLLED STUDY; FEMALE; FERRET; GENE EXPRESSION; GENE TRANSFER; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H5N1; LD 50; MOUSE; NASOPHARYNX; NONHUMAN; NOSE MUCOSA; PANDEMIC INFLUENZA; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RHESUS MONKEY; SEROTYPE; VIRUS ISOLATION; VIRUS STRAIN;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; DEPENDOVIRUS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; FERRETS; GENE TRANSFER TECHNIQUES; MACACA MULATTA; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS;

EID: 84880520936     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3006729     Document Type: Article

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