Generalizing polygenic risk scores from Europeans to Hispanics/Latinos

Genetic Epidemiology

Volumn 43, Issue 1, 2019, Pages 50-62

  Grinde, Kelsey E ^a   Qi, Qibin ^b   Thornton, Timothy A ^a   Liu, Simin ^c   Shadyab, Aladdin H ^d   Chan, Kei Hang K ^c,e   Reiner, Alexander P ^f   Sofer, Tamar ^g,h  

^a UNIVERSITY OF WASHINGTON   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c BROWN UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^f USA   (United States)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

^h HARVARD MEDICAL SCHOOL   (United States)

Author keywords

admixed populations; genetic diversity; linkage disequilibrium

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; EUROPEAN; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE STRUCTURE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SCREENING; GENETIC TRAIT; GENOTYPE; HISPANIC; HUMAN; POLYGENIC RISK SCORE; POPULATION GENETICS; POPULATION RESEARCH; SCORING SYSTEM; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; WOMEN'S HEALTH; BIOLOGICAL MODEL; CAUCASIAN; COMPUTER SIMULATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MULTIFACTORIAL INHERITANCE; RISK FACTOR;

COMPUTER SIMULATION; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENOME-WIDE ASSOCIATION STUDY; HISPANIC AMERICANS; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MULTIFACTORIAL INHERITANCE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 85055699246     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.22166     Document Type: Article

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