A2BAR activation attenuates acute lung injury by inhibiting alveolar epithelial cell apoptosis both in vivo and in vitro

American Journal of Physiology - Cell Physiology

Volumn 315, Issue 4, 2018, Pages C558-C570

  Xu, Xiaotao ^a   Zhu, Qingwei ^a   Niu, Fangfang ^a   Zhang, Rong ^a   Wang, Yan ^a   Wang, Wenying ^a   Sun, Dawei ^a   Wang, Xintao ^a   Wang, Aizhong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

Author keywords

A2B adenosine receptors; Alveolar epithelial cells; Apoptosis; MAPK; Mitochondrial signaling pathway

Indexed keywords

ADENOSINE A2B RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; BAY 606583; CASPASE 9; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; OLEIC ACID; PSB 1115; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 1-PROPYL-8-(4-SULFOPHENYL)XANTHINE; AMINOPYRIDINE DERIVATIVE; BAY 60-6583; CASPASE 3; XANTHINE DERIVATIVE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN RNA BINDING; A-549 CELL LINE; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECT; LUNG; MAPK SIGNALING; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

A549 CELLS; ACUTE LUNG INJURY; ALVEOLAR EPITHELIAL CELLS; AMINOPYRIDINES; ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; HUMANS; HYDROGEN PEROXIDE; LUNG; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; OLEIC ACID; RECEPTOR, ADENOSINE A2B; SIGNAL TRANSDUCTION; XANTHINES;

EID: 85054458819     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00294.2017     Document Type: Article

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