Multiple optimal phenotypes overcome redox and glycolytic intermediate metabolite imbalances in Escherichia coli pgi knockout evolutions

Applied and Environmental Microbiology

Volumn 84, Issue 19, 2018, Pages

  McCloskey, Douglas ^a,b   Xu, Sibei ^a   Sandberg, Troy E ^a   Brunk, Elizabeth ^a   Hefner, Ying ^a   Szubin, Richard ^a   Feist, Adam M ^a,b   Palsson, Bernhard O ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Chalmers University of Technology   (Denmark)

Author keywords

Adaptive laboratory evolution; Escherichia coli; Multi omics analysis; Mutation analysis; Pgi gene knockout; Systems biology

Indexed keywords

ESCHERICHIA COLI PROTEIN; GLUCOSE 6 PHOSPHATE ISOMERASE; PGI PROTEIN, E COLI;

ENZYMOLOGY; ESCHERICHIA COLI K 12; GENE KNOCKOUT; GENETICS; GLYCOLYSIS; METABOLISM; MUTATION; OXIDATION REDUCTION REACTION; PHENOTYPE;

ESCHERICHIA COLI K12; ESCHERICHIA COLI PROTEINS; GENE KNOCKOUT TECHNIQUES; GLUCOSE-6-PHOSPHATE ISOMERASE; GLYCOLYSIS; MUTATION; OXIDATION-REDUCTION; PHENOTYPE;

EID: 85053445003     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.00823-18     Document Type: Article

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