A model-driven quantitative metabolomics analysis of aerobic and anaerobic metabolism in E. coli K-12 MG1655 that is biochemically and thermodynamically consistent

Biotechnology and Bioengineering

Volumn 111, Issue 4, 2014, Pages 803-815

  Mccloskey, Douglas ^a   Gangoiti, Jon A ^b   King, Zachary A ^a   Naviaux, Robert K ^b   Barshop, Bruce A ^b   Palsson, Bernhard O ^a,c   Feist, Adam M ^a,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Technical University of Denmark   (Denmark)

Author keywords

Anaerobic aerobic E. coli; Constraint based analysis; Genome scale modeling; Metabolomics; Thermodynamics analysis

Indexed keywords

COMPUTER SIMULATION; ESCHERICHIA COLI; GENES; METABOLISM; THERMODYNAMICS;

CONSTRAINT-BASED ANALYSIS; E. COLI; GENOME-SCALE MODEL; METABOLOMICS; THERMODYNAMICS ANALYSIS;

CHEMICAL ANALYSIS;

CARBON 13;

AEROBIC METABOLISM; AMINO ACID METABOLISM; ANAEROBIC GROWTH; ANAEROBIC METABOLISM; ANALYTIC METHOD; ARTICLE; BACTERIAL GENETICS; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM CULTURE; BIOCHEMISTRY; BIOLOGICAL MODEL; CALIBRATION; CARBOHYDRATE METABOLISM; CHROMATOGRAPHY; COMPUTER MODEL; CULTURE MEDIUM; CULTURE VESSEL; ESCHERICHIA COLI K 12; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GENOME SCALE MODEL; GROWTH RATE; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; NONHUMAN; NUCLEOTIDE METABOLISM; OXIDATION REDUCTION STATE; QUANTITATIVE ANALYSIS; REFRACTION INDEX; SENSITIVITY ANALYSIS; STEADY STATE; THERMODYNAMICS;

ESCHERICHIA COLI; ESCHERICHIA COLI K12;

ANAEROBIC/AEROBIC E. COLI; CONSTRAINT-BASED ANALYSIS; GENOME-SCALE MODELING; METABOLOMICS; THERMODYNAMICS ANALYSIS;

AEROBIOSIS; ANAEROBIOSIS; BIOENGINEERING; BIOREACTORS; ESCHERICHIA COLI; METABOLIC NETWORKS AND PATHWAYS; METABOLOMICS; MODELS, BIOLOGICAL; THERMODYNAMICS;

EID: 84894231008     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25133     Document Type: Article

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