Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors

Journal of Clinical Investigation

Volumn 128, Issue 9, 2018, Pages 3794-3805

  Weiss, Jonathan M ^a   Davies, Luke C ^b   Karwan, Megan ^c   Ileva, Lilia ^c   Ozaki, Michelle K ^d   Cheng, Robert Y S ^a   Ridnour, Lisa A ^a   Annunziata, Christina M ^d   Wink, David A ^a   McVicar, Daniel W ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITIC ACID; ITACONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; FATTY ACID; HYDROLYASE; IRG1 PROTEIN, HUMAN; IRG1 PROTEIN, MOUSE; PROTEIN; SMALL INTERFERING RNA; SUCCINIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; ASCITES FLUID; CANCER PATIENT; CONTROLLED STUDY; FATTY ACID OXIDATION; FEASIBILITY STUDY; FEMALE; GLYCOLYSIS; HUMAN; IMMUNE RESPONSE; LENTIVIRUS; MACROPHAGE; MELANOMA B16; METABOLOMICS; MONOCYTE; MOUSE; NONHUMAN; OVARY CARCINOMA; OXIDATIVE PHOSPHORYLATION; PERITONEAL TISSUE; PERITONEUM TUMOR; PRIORITY JOURNAL; TUMOR GROWTH; ANIMAL; C57BL MOUSE; DISEASE EXACERBATION; EXPERIMENTAL MELANOMA; GENETICS; KNOCKOUT MOUSE; METABOLISM; OVARY TUMOR; PATHOLOGY; PERITONEUM MACROPHAGE; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; CELL LINE, TUMOR; DISEASE PROGRESSION; FATTY ACIDS; FEMALE; GLYCOLYSIS; HUMANS; HYDRO-LYASES; MACROPHAGES, PERITONEAL; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; OVARIAN NEOPLASMS; OXIDATIVE PHOSPHORYLATION; PERITONEAL NEOPLASMS; PROTEINS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SUCCINATES; TUMOR BURDEN;

EID: 85052588049     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI99169     Document Type: Article

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