Itaconic Acid: The Surprising Role of an Industrial Compound as a Mammalian Antimicrobial Metabolite

Annual Review of Nutrition

Volumn 35, Issue 1, 2015, Pages 451-473

  Cordes, Thekla ^a,b   Michelucci, Alessandro ^a   Hiller, Karsten ^a  

^a UNIVERSITY OF LUXEMBOURG   (Luxembourg)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

cis aconitic acid decarboxylase; Immune responsive gene 1 protein (IRG1); Inflammation; Macrophage; Metabolic immunity; Metabolism

Indexed keywords

CARBOXYLYASE; CIS ACONITIC ACID DECARBOXYLASE; GLYOXYLIC ACID; IMMUNE RESPONSIVE GENE 1 PROTEIN; ITACONIC ACID; PROTEIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; CITRAMALATE; GLYOXYLIC ACID DERIVATIVE; IRG1 PROTEIN, HUMAN; MALIC ACID DERIVATIVE; SUCCINIC ACID DERIVATIVE;

ACID SECRETION; ANTIMICROBIAL ACTIVITY; ASPERGILLUS TERREUS; BACTERIAL GROWTH; BIOSYNTHESIS; CELL COMPARTMENTALIZATION; CELLULAR DISTRIBUTION; ENERGY METABOLISM; ENZYME ACTIVITY; GENE EXPRESSION; GROWTH INHIBITION; IMMUNOCOMPETENT CELL; INDUSTRIAL PRODUCTION; INFLAMMATION; MAMMAL CELL; METABOLITE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SYNTHESIS; ANIMAL; ANTAGONISTS AND INHIBITORS; ASPERGILLUS; BACTERIUM; CITRIC ACID CYCLE; DRUG EFFECTS; GENETICS; HUMAN; IMMUNE SYSTEM; MAMMAL; METABOLISM; PHYSIOLOGY;

MAMMALIA;

ANIMALS; ANTI-INFECTIVE AGENTS; ASPERGILLUS; BACTERIA; CITRIC ACID CYCLE; ENERGY METABOLISM; GENE EXPRESSION; GLYOXYLATES; HUMANS; IMMUNE SYSTEM; INFLAMMATION; MALATES; MAMMALS; PROTEINS; SUCCINATES;

EID: 84937572123     PISSN: 01999885     EISSN: 15454312     Source Type: Book Series    
DOI: 10.1146/annurev-nutr-071714-034243     Document Type: Review

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