Immune responsive gene 1, a novel oncogene, increases the growth and tumorigenicity of glioma

Oncology Reports

Volumn 32, Issue 5, 2014, Pages 1957-1966

  Pan, Jun ^a   Zhao, Xiaoyong ^a   Lin, Chunnan ^a   Xu, Hongchao ^a   Yin, Zhilin ^a   Liu, Tianzhu ^a   Zhang, Shizhong ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Glioma; Immune responsive gene 1; Oncogene; Tumorigenicity

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P21; SMALL INTERFERING RNA; STAT3 PROTEIN; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; VIMENTIN; CELL CYCLE PROTEIN; IRG1 PROTEIN, HUMAN; PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STAGING; CARCINOGENESIS; CARCINOGENICITY; CONTROLLED STUDY; DRUG EFFECT; EPIGENETICS; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; GLIOMA; GLIOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSIVE GENE 1; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; ONCOGENE; PROTEIN EXPRESSION; RNA INTERFERENCE; TUMOR GROWTH; TUMOR INVASION; UPREGULATION; AGED; ANIMAL; CANCER TRANSPLANTATION; GENETICS; METABOLISM; MIDDLE AGED; NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; FEMALE; GLIOMA; HUMANS; MALE; MICE; MICE, NUDE; MIDDLE AGED; NEOPLASM TRANSPLANTATION; ONCOGENES; PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84907291040     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3474     Document Type: Article

References (26)

1. Hamza MA and Gilbert M: Targeted therapy in gliomas. Curr Oncol Rep 16: 379, 2014.
2. Kaufmann JK and Chiocca EA: Glioma virus therapies between bench and bedside. Neuro Oncol 16: 334-351, 2014.
3. Lohkamp B, Bauerle B, Rieger PG and Schneider G: Threedimensional structure of iminodisuccinate epimerase defines the fold of the MmgE/PrpD protein family. J Mol Biol 362: 555-566, 2006.
4. Lee CG, Demarquoy J, Jackson MJ and O'Brien WE: Molecular cloning and characterization of a murine LPS-inducible cDNA. J Immunol 152: 5758-5767, 1994.
5. Gautam A, Dixit S, Philipp MT, et al: Interleukin-10 alters effector functions of multiple genes induced by Borrelia burgdorferi in macrophages to regulate Lyme disease inflammation. Infect Immun 79: 4876-4892, 2011.
6. Li Y, Zhang P, Wang C, et al: Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species. J Biol Chem 288: 16225-16234, 2013.
7. Lee CG, Jenkins NA, Gilbert DJ, Copeland NG and O'Brien WE: Cloning and analysis of gene regulation of a novel LPS-inducible cDNA. Immunogenetics 41: 263-270, 1995.
8. Shi S, Blumenthal A, Hickey CM, Gandotra S, Levy D and Ehrt S: Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-Alphabeta receptor and STAT1. J Immunol 175: 3318-3328, 2005.
9. Muccioli M, Sprague L, Nandigam H, Pate M and Benencia F: Toll-like receptors as novel therapeutic targets for ovarian cancer. ISRN Oncol 2012: 642141, 2012.
10. Hall CJ, Boyle RH, Astin JW, et al: Immunoresponsive gene 1 augments bactericidal activity of macrophage-lineage cells by regulating β-oxidation-dependent mitochondrial ROS production. Cell Metab 18: 265-278, 2013.
11. Chiba Y, Mizoguchi I, Mitobe K, et al: IL-27 enhances the expression of TRAIL and TLR3 inhuman melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner. PLoS One 8: e76159, 2013.
12. Song Q, Li Y, Zheng X, et al: MTA1 contributes to actin cytoskeleton reorganization and metastasis of nasopharyngeal carcinoma by modulating Rho GTPases and Hedgehog signaling. Int J Biochem Cell Biol 45: 1439-1446, 2013.
13. Lathia JD, Li M, Hall PE, et al: Laminin alpha 2 enables glioblastoma stem cell growth. Ann Neurol 72: 766-778, 2012.
14. Cheng L, Huang Z, Zhou W, et al: Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell 153: 139-152, 2013.
15. Islam KN, Bae JW, Gao E and Koch WJ: Regulation of nuclear factor κB (NF-κB) in the nucleus of cardiomyocytes by G protein-coupled receptor kinase 5 (GRK5). J Biol Chem 288: 35683-35689, 2013.
16. Cheah SC, Lai SL, Lee ST, Hadi AH and Mustafa MR: Panduratin A, a possible inhibitor in metastasized A549 cells through inhibition of NF-kappa B translocation and chemoinvasion. Molecules 18: 8764-8778, 2013.
17. Zhao L, Wang H, Sun X and Ding Y: Comparative proteomic analysis identifies proteins associated with the development and progression of colorectal carcinoma. FEBS J 277: 4195-4204, 2010.
18. Wang F, Qiao Y, Yu J, et al: FBX8 acts as an invasion and metastasis suppressor and correlates with poor survival in hepatocellular carcinoma. PLoS One 8: e65495, 2013.
19. Huang J, Ye X, Guan J, et al: Tiam1 is associated with hepatocellular carcinoma metastasis. Int J Cancer 132: 90-100, 2013.
20. Michelucci A, Cordes T, Ghelfi J, et al: Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production. Proc Natl Acad Sci USA 110: 7820-7825, 2013.
21. Kovesdi I, Reichel R and Nevins JR: E1A transcription induction: enhanced binding of a factor to upstream promoter sequences. Science 231: 719-722, 1986.
22. Wang WJ, Wu SP, Liu JB, et al: MYC regulation of CHK1 and CHK2 promotes radioresistance in a stem cell-like population of nasopharyngeal carcinoma cells. Cancer Res 73: 1219-1231, 2013.
23. Lee HH, Lee SR and Leem SH: Tristetraprolin regulates prostate cancer cell growth through suppression of E2F1. J Microbiol Biotechnol 24: 287-294, 2013.
24. Kim MK, Kang YJ, Kim DH, et al: A novel hydroxamic acid derivative, MHY218, induces apoptosis and cell cycle arrest through downregulation of NF-κB in HCT116 human colon cancer cells. Int J Oncol 44: 256-264, 2014.
25. Kim A, Yim NH, Im M, Jung YP, Kim T and Ma JY: Suppression of the invasive potential of highly malignant tumor cells by KIOM-C, a novel herbal medicine, via inhibition of NF-κB activation and MMP-9 expression. Oncol Rep 31: 287-297, 2014.
26. Zhang W and Grivennikov SI: Top Notch cancer stem cells by paracrine NF-κB signaling in breast cancer. Breast Cancer Res 15: 316, 2013.