메뉴 건너뛰기




Volumn 5, Issue , 2018, Pages

Temporal Dynamics of Gene Expression During Endothelial Cell Differentiation From Human iPS Cells: A Comparison Study of Signalling Factors and Small Molecules

Author keywords

cardiovascular diseases; cell therapy; endothelial differentiation; iPS cells; RNA sequencing; transcription factors

Indexed keywords

MEMBRANE ANTIGEN; VASCULOTROPIN;

EID: 85052545933     PISSN: None     EISSN: 2297055X     Source Type: Journal    
DOI: 10.3389/fcvm.2018.00016     Document Type: Article
Times cited : (8)

References (90)
  • 1
    • 84950104119 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2016 update: a report from the American Heart Association
    • Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Heart disease and stroke statistics-2016 update: a report from the American Heart Association. Circulation (2016) 133(4):e38–60. 10.1161/CIR.0000000000000350
    • (2016) Circulation , vol.133 , Issue.4 , pp. e38-e60
    • Mozaffarian, D.1    Benjamin, E.J.2    Go, A.S.3    Arnett, D.K.4    Blaha, M.J.5    Cushman, M.6
  • 2
    • 84881114106 scopus 로고    scopus 로고
    • Therapeutic angiogenesis for critical limb ischaemia
    • Annex BH. Therapeutic angiogenesis for critical limb ischaemia. Nat Rev Cardiol (2013) 10(7):387–96. 10.1038/nrcardio.2013.70
    • (2013) Nat Rev Cardiol , vol.10 , Issue.7 , pp. 387-396
    • Annex, B.H.1
  • 3
    • 85019723959 scopus 로고    scopus 로고
    • Angiogenic gene therapy in cardiovascular diseases: dream or vision?
    • Ylä-Herttuala S, Bridges C, Katz MG, Korpisalo P. Angiogenic gene therapy in cardiovascular diseases: dream or vision? Eur Heart J (2017) 38(18):ehw547–71. 10.1093/eurheartj/ehw547
    • (2017) Eur Heart J , vol.38 , Issue.18 , pp. ehw547-ehw571
    • Ylä-Herttuala, S.1    Bridges, C.2    Katz, M.G.3    Korpisalo, P.4
  • 4
    • 84984630348 scopus 로고    scopus 로고
    • Blood vessel repair and regeneration in the ischaemic heart
    • Zhang H, van Olden C, Sweeney D, Martin-Rendon E. Blood vessel repair and regeneration in the ischaemic heart. Open Heart (2014) 1(1):e000016. 10.1136/openhrt-2013-000016
    • (2014) Open Heart , vol.1 , Issue.1 , pp. e000016
    • Zhang, H.1    van Olden, C.2    Sweeney, D.3    Martin-Rendon, E.4
  • 5
    • 77951758771 scopus 로고    scopus 로고
    • Endothelial progenitor cell transplantation improves long-term stroke outcome in mice
    • Fan Y, Shen F, Frenzel T, Zhu W, Ye J, Liu J, et al. Endothelial progenitor cell transplantation improves long-term stroke outcome in mice. Ann Neurol (2010) 67(4):488–97. 10.1002/ana.21919
    • (2010) Ann Neurol , vol.67 , Issue.4 , pp. 488-497
    • Fan, Y.1    Shen, F.2    Frenzel, T.3    Zhu, W.4    Ye, J.5    Liu, J.6
  • 6
    • 85017348801 scopus 로고    scopus 로고
    • Cardiovascular gene therapy: past, present, and future
    • Ylä-Herttuala S, Baker AH. Cardiovascular gene therapy: past, present, and future. Mol Ther (2017) 25(5):1095–106. 10.1016/j.ymthe.2017.03.027
    • (2017) Mol Ther , vol.25 , Issue.5 , pp. 1095-1106
    • Ylä-Herttuala, S.1    Baker, A.H.2
  • 7
    • 30344437303 scopus 로고    scopus 로고
    • VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells
    • Grunewald M, Avraham I, Dor Y, Bachar-Lustig E, Itin A, Jung S, et al. VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell (2006) 124(1):175–89. 10.1016/j.cell.2005.10.036
    • (2006) Cell , vol.124 , Issue.1 , pp. 175-189
    • Grunewald, M.1    Avraham, I.2    Dor, Y.3    Bachar-Lustig, E.4    Itin, A.5    Jung, S.6
  • 8
    • 33748041454 scopus 로고    scopus 로고
    • Increase in vascular permeability and vasodilation are critical for proangiogenic effects of stem cell therapy
    • You D, Waeckel L, Ebrahimian TG, Blanc-Brude O, Foubert P, Barateau V, et al. Increase in vascular permeability and vasodilation are critical for proangiogenic effects of stem cell therapy. Circulation (2006) 114(4):328–38. 10.1161/CIRCULATIONAHA.105.589937
    • (2006) Circulation , vol.114 , Issue.4 , pp. 328-338
    • You, D.1    Waeckel, L.2    Ebrahimian, T.G.3    Blanc-Brude, O.4    Foubert, P.5    Barateau, V.6
  • 9
    • 0032525207 scopus 로고    scopus 로고
    • Endothelial cells in physiology and in the pathophysiology of vascular disorders
    • Cines DB, Pollak ES, Buck CA, Loscalzo J, Zimmerman GA, Mcever RP, et al. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood (1998) 91(10):3527–61.
    • (1998) Blood , vol.91 , Issue.10 , pp. 3527-3561
    • Cines, D.B.1    Pollak, E.S.2    Buck, C.A.3    Loscalzo, J.4    Zimmerman, G.A.5    Mcever, R.P.6
  • 10
    • 2942733214 scopus 로고    scopus 로고
    • Role of Endothelial Dysfunction in Atherosclerosis
    • Davignon J, Ganz P. Role of Endothelial Dysfunction in Atherosclerosis. Circulation (2004) 109(23_suppl_1):III-27–32. 10.1161/01.CIR.0000131515.03336.f8
    • (2004) Circulation , vol.109
    • Davignon, J.1    Ganz, P.2
  • 11
    • 85048387963 scopus 로고    scopus 로고
    • Growth differentiation factor 6 promotes vascular stability by restraining vascular endothelial growth factor signaling
    • Krispin S, Stratman AN, Melick CH, Stan RV, Malinverno M, Gleklen J, et al. Growth differentiation factor 6 promotes vascular stability by restraining vascular endothelial growth factor signaling. Arterioscler Thromb Vasc Biol (2018) 38(2):353–62. 10.1161/ATVBAHA.117.309571
    • (2018) Arterioscler Thromb Vasc Biol , vol.38 , Issue.2 , pp. 353-362
    • Krispin, S.1    Stratman, A.N.2    Melick, C.H.3    Stan, R.V.4    Malinverno, M.5    Gleklen, J.6
  • 12
    • 85013124230 scopus 로고    scopus 로고
    • The link between angiogenesis and endothelial metabolism
    • Potente M, Carmeliet P. The link between angiogenesis and endothelial metabolism. Annu Rev Physiol (2017) 79:43–66. 10.1146/annurev-physiol-021115-105134
    • (2017) Annu Rev Physiol , vol.79 , pp. 43-66
    • Potente, M.1    Carmeliet, P.2
  • 13
    • 33644683263 scopus 로고    scopus 로고
    • Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization
    • Davis GE, Senger DR. Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ Res (2005) 97(11):1093–107. 10.1161/01.RES.0000191547.64391.e3
    • (2005) Circ Res , vol.97 , Issue.11 , pp. 1093-1107
    • Davis, G.E.1    Senger, D.R.2
  • 14
    • 33646673174 scopus 로고    scopus 로고
    • Vascular wall resident progenitor cells: a source for postnatal vasculogenesis
    • Zengin E, Chalajour F, Gehling UM, Ito WD, Treede H, Lauke H, et al. Vascular wall resident progenitor cells: a source for postnatal vasculogenesis. Development (2006) 133(8):1543–51. 10.1242/dev.02315
    • (2006) Development , vol.133 , Issue.8 , pp. 1543-1551
    • Zengin, E.1    Chalajour, F.2    Gehling, U.M.3    Ito, W.D.4    Treede, H.5    Lauke, H.6
  • 15
    • 0031019745 scopus 로고    scopus 로고
    • Isolation of putative progenitor endothelial cells for angiogenesis
    • Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science (1997) 275(5302):964–6. 10.1126/science.275.5302.964
    • (1997) Science , vol.275 , Issue.5302 , pp. 964-966
    • Asahara, T.1    Murohara, T.2    Sullivan, A.3    Silver, M.4    van der Zee, R.5    Li, T.6
  • 16
    • 85047745818 scopus 로고    scopus 로고
    • E2F1 suppresses oxidative metabolism and endothelial differentiation of bone marrow progenitor cells
    • Xu S, Tao J, Yang L, Zhang E, Boriboun C, Zhou J, et al. E2F1 suppresses oxidative metabolism and endothelial differentiation of bone marrow progenitor cells. Circ Res (2018):CIRCRESAHA.117.311814. 10.1161/CIRCRESAHA.117.311814
    • (2018) Circ Res
    • Xu, S.1    Tao, J.2    Yang, L.3    Zhang, E.4    Boriboun, C.5    Zhou, J.6
  • 18
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 126(4):663–76. 10.1016/j.cell.2006.07.024
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 19
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 318(5858):1917–20. 10.1126/science.1151526
    • (2007) Science , vol.318 , Issue.5858 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3    Antosiewicz-Bourget, J.4    Frane, J.L.5    Tian, S.6
  • 20
    • 84904293670 scopus 로고    scopus 로고
    • Induced pluripotent stem cells for regenerative medicine
    • Hirschi KK, Li S, Roy K. Induced pluripotent stem cells for regenerative medicine. Annu Rev Biomed Eng (2014) 16:277–94. 10.1146/annurev-bioeng-071813-105108
    • (2014) Annu Rev Biomed Eng , vol.16 , pp. 277-294
    • Hirschi, K.K.1    Li, S.2    Roy, K.3
  • 21
    • 85051604758 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: applications in regenerative medicine, disease modeling, and drug discovery
    • Singh VK, Kalsan M, Kumar N, Saini A, Chandra R. Induced pluripotent stem cells: applications in regenerative medicine, disease modeling, and drug discovery. Front Cell Dev Biol (2015) 3:2. 10.3389/fcell.2015.00002
    • (2015) Front Cell Dev Biol , vol.3
    • Singh, V.K.1    Kalsan, M.2    Kumar, N.3    Saini, A.4    Chandra, R.5
  • 22
    • 84866175595 scopus 로고    scopus 로고
    • Vascular differentiation from embryonic stem cells: novel technologies and therapeutic promises
    • Descamps B, Emanueli C. Vascular differentiation from embryonic stem cells: novel technologies and therapeutic promises. Vascul Pharmacol (2012) 56(5-6):267–79. 10.1016/j.vph.2012.03.007
    • (2012) Vascul Pharmacol , vol.56 , Issue.5-6 , pp. 267-279
    • Descamps, B.1    Emanueli, C.2
  • 23
    • 85015275104 scopus 로고    scopus 로고
    • Efficient and robust differentiation of endothelial cells from human induced pluripotent stem cells via lineage control with VEGF and cyclic AMP
    • Ikuno T, Masumoto H, Yamamizu K, Yoshioka M, Minakata K, Ikeda T, et al. Efficient and robust differentiation of endothelial cells from human induced pluripotent stem cells via lineage control with VEGF and cyclic AMP. PLoS ONE (2017) 12(3):e0173271. 10.1371/journal.pone.0173271
    • (2017) PLoS ONE , vol.12 , Issue.3
    • Ikuno, T.1    Masumoto, H.2    Yamamizu, K.3    Yoshioka, M.4    Minakata, K.5    Ikeda, T.6
  • 24
    • 76349087336 scopus 로고    scopus 로고
    • Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent
    • James D, Nam HS, Seandel M, Nolan D, Janovitz T, Tomishima M, et al. Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nat Biotechnol (2010) 28(2):161–6. 10.1038/nbt.1605
    • (2010) Nat Biotechnol , vol.28 , Issue.2 , pp. 161-166
    • James, D.1    Nam, H.S.2    Seandel, M.3    Nolan, D.4    Janovitz, T.5    Tomishima, M.6
  • 25
    • 84866865798 scopus 로고    scopus 로고
    • ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells
    • Joo HJ, Choi DK, Lim JS, Park JS, Lee SH, Song S, et al. ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells. Blood (2012) 120(13):2733–44. 10.1182/blood-2012-04-421610
    • (2012) Blood , vol.120 , Issue.13 , pp. 2733-2744
    • Joo, H.J.1    Choi, D.K.2    Lim, J.S.3    Park, J.S.4    Lee, S.H.5    Song, S.6
  • 26
    • 78650512220 scopus 로고    scopus 로고
    • Pluripotent stem cell differentiation into vascular cells: a novel technology with promises for vascular re(generation)
    • Kane NM, Xiao Q, Baker AH, Luo Z, Xu Q, Emanueli C. Pluripotent stem cell differentiation into vascular cells: a novel technology with promises for vascular re(generation). Pharmacol Ther (2011) 129(1):29–49. 10.1016/j.pharmthera.2010.10.004
    • (2011) Pharmacol Ther , vol.129 , Issue.1 , pp. 29-49
    • Kane, N.M.1    Xiao, Q.2    Baker, A.H.3    Luo, Z.4    Xu, Q.5    Emanueli, C.6
  • 27
    • 84971663847 scopus 로고    scopus 로고
    • Differentiation of functional endothelial cells from human induced pluripotent stem cells: a novel, highly efficient and cost effective method
    • Liu X, Qi J, Xu X, Zeisberg M, Guan K, Zeisberg EM. Differentiation of functional endothelial cells from human induced pluripotent stem cells: a novel, highly efficient and cost effective method. Differentiation (2016) 92(4):225–36. 10.1016/j.diff.2016.05.004
    • (2016) Differentiation , vol.92 , Issue.4 , pp. 225-236
    • Liu, X.1    Qi, J.2    Xu, X.3    Zeisberg, M.4    Guan, K.5    Zeisberg, E.M.6
  • 29
    • 49649120250 scopus 로고    scopus 로고
    • Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells
    • Narazaki G, Uosaki H, Teranishi M, Okita K, Kim B, Matsuoka S, et al. Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation (2008) 118(5):498–506. 10.1161/CIRCULATIONAHA.108.769562
    • (2008) Circulation , vol.118 , Issue.5 , pp. 498-506
    • Narazaki, G.1    Uosaki, H.2    Teranishi, M.3    Okita, K.4    Kim, B.5    Matsuoka, S.6
  • 30
    • 78650450972 scopus 로고    scopus 로고
    • Efficient differentiation of human pluripotent stem cells into functional CD34+ progenitor cells by combined modulation of the MEK/ERK and BMP4 signaling pathways
    • Park SW, Jun Koh Y, Jeon J, Cho YH, Jang MJ, Kang Y, et al. Efficient differentiation of human pluripotent stem cells into functional CD34+ progenitor cells by combined modulation of the MEK/ERK and BMP4 signaling pathways. Blood (2010) 116(25):5762–72. 10.1182/blood-2010-04-280719
    • (2010) Blood , vol.116 , Issue.25 , pp. 5762-5772
    • Park, S.W.1    Jun Koh, Y.2    Jeon, J.3    Cho, Y.H.4    Jang, M.J.5    Kang, Y.6
  • 31
    • 33747395381 scopus 로고    scopus 로고
    • Adrenomedullin/cyclic AMP pathway induces Notch activation and differentiation of arterial endothelial cells from vascular progenitors
    • Yurugi-Kobayashi T, Itoh H, Schroeder T, Nakano A, Narazaki G, Kita F, et al. Adrenomedullin/cyclic AMP pathway induces Notch activation and differentiation of arterial endothelial cells from vascular progenitors. Arterioscler Thromb Vasc Biol (2006) 26(9):1977–84. 10.1161/01.ATV.0000234978.10658.41
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.9 , pp. 1977-1984
    • Yurugi-Kobayashi, T.1    Itoh, H.2    Schroeder, T.3    Nakano, A.4    Narazaki, G.5    Kita, F.6
  • 32
    • 85025697297 scopus 로고    scopus 로고
    • Functional characterization of human pluripotent stem cell-derived arterial endothelial cells
    • Zhang J, Chu LF, Hou Z, Schwartz MP, Hacker T, Vickerman V, et al. Functional characterization of human pluripotent stem cell-derived arterial endothelial cells. Proc Natl Acad Sci USA (2017) 114(30):E6072–8. 10.1073/pnas.1702295114
    • (2017) Proc Natl Acad Sci USA , vol.114 , Issue.30 , pp. E6072-E6078
    • Zhang, J.1    Chu, L.F.2    Hou, Z.3    Schwartz, M.P.4    Hacker, T.5    Vickerman, V.6
  • 33
    • 39349091570 scopus 로고    scopus 로고
    • Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells
    • Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, et al. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood (2008) 111(4):1933–41. 10.1182/blood-2007-02-074120
    • (2008) Blood , vol.111 , Issue.4 , pp. 1933-1941
    • Zhang, P.1    Li, J.2    Tan, Z.3    Wang, C.4    Liu, T.5    Chen, L.6
  • 34
    • 84938503232 scopus 로고    scopus 로고
    • Generating induced pluripotent stem cell derived endothelial cells and induced endothelial cells for cardiovascular disease modelling and therapeutic angiogenesis
    • Clayton ZE, Sadeghipour S, Patel S. Generating induced pluripotent stem cell derived endothelial cells and induced endothelial cells for cardiovascular disease modelling and therapeutic angiogenesis. Int J Cardiol (2015) 197:116–22. 10.1016/j.ijcard.2015.06.038
    • (2015) Int J Cardiol , vol.197 , pp. 116-122
    • Clayton, Z.E.1    Sadeghipour, S.2    Patel, S.3
  • 35
    • 0347363474 scopus 로고    scopus 로고
    • TGF-beta receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells
    • Watabe T, Nishihara A, Mishima K, Yamashita J, Shimizu K, Miyazawa K, et al. TGF-beta receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells. J Cell Biol (2003) 163(6):1303–11. 10.1083/jcb.200305147
    • (2003) J Cell Biol , vol.163 , Issue.6 , pp. 1303-1311
    • Watabe, T.1    Nishihara, A.2    Mishima, K.3    Yamashita, J.4    Shimizu, K.5    Miyazawa, K.6
  • 36
    • 84879245772 scopus 로고    scopus 로고
    • Chondrogenic differentiation of human pluripotent stem cells in chondrocyte co-culture
    • Qu C, Puttonen KA, Lindeberg H, Ruponen M, Hovatta O, Koistinaho J, et al. Chondrogenic differentiation of human pluripotent stem cells in chondrocyte co-culture. Int J Biochem Cell Biol (2013) 45(8):1802–12. 10.1016/j.biocel.2013.05.029
    • (2013) Int J Biochem Cell Biol , vol.45 , Issue.8 , pp. 1802-1812
    • Qu, C.1    Puttonen, K.A.2    Lindeberg, H.3    Ruponen, M.4    Hovatta, O.5    Koistinaho, J.6
  • 38
    • 84884689200 scopus 로고    scopus 로고
    • Improved method of producing human neural progenitor cells of high purity and in large quantities from pluripotent stem cells for transplantation studies
    • Puttonen KA, Ruponen M, Kauppinen R, Wojciechowski S, Hovatta O, Koistinaho J. Improved method of producing human neural progenitor cells of high purity and in large quantities from pluripotent stem cells for transplantation studies. Cell Transplant (2013) 22(10):1753–66. 10.3727/096368912X658764
    • (2013) Cell Transplant , vol.22 , Issue.10 , pp. 1753-1766
    • Puttonen, K.A.1    Ruponen, M.2    Kauppinen, R.3    Wojciechowski, S.4    Hovatta, O.5    Koistinaho, J.6
  • 39
    • 34250206996 scopus 로고    scopus 로고
    • A ROCK inhibitor permits survival of dissociated human embryonic stem cells
    • Watanabe K, Ueno M, Kamiya D, Nishiyama A, Matsumura M, Wataya T, et al. A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Nat Biotechnol (2007) 25(6):681–6. 10.1038/nbt1310
    • (2007) Nat Biotechnol , vol.25 , Issue.6 , pp. 681-686
    • Watanabe, K.1    Ueno, M.2    Kamiya, D.3    Nishiyama, A.4    Matsumura, M.5    Wataya, T.6
  • 40
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
    • Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest (1973) 52(11):2745–56. 10.1172/JCI107470
    • (1973) J Clin Invest , vol.52 , Issue.11 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 41
    • 33645472584 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and endothelial cell functions are novel sulforaphane-mediated mechanisms in chemoprevention
    • Bertl E, Bartsch H, Gerhäuser C. Inhibition of angiogenesis and endothelial cell functions are novel sulforaphane-mediated mechanisms in chemoprevention. Mol Cancer Ther (2006) 5(3):575–85. 10.1158/1535-7163.MCT-05-0324
    • (2006) Mol Cancer Ther , vol.5 , Issue.3 , pp. 575-585
    • Bertl, E.1    Bartsch, H.2    Gerhäuser, C.3
  • 43
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell (2010) 38(4):576–89. 10.1016/j.molcel.2010.05.004
    • (2010) Mol Cell , vol.38 , Issue.4 , pp. 576-589
    • Heinz, S.1    Benner, C.2    Spann, N.3    Bertolino, E.4    Lin, Y.C.5    Laslo, P.6
  • 44
    • 75249087100 scopus 로고    scopus 로고
    • edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson MD, Mccarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics (2010) 26(1):139–40. 10.1093/bioinformatics/btp616
    • (2010) Bioinformatics , vol.26 , Issue.1 , pp. 139-140
    • Robinson, M.D.1    Mccarthy, D.J.2    Smyth, G.K.3
  • 45
    • 3142756502 scopus 로고    scopus 로고
    • Open source clustering software
    • de Hoon MJ, Imoto S, Nolan J, Miyano S. Open source clustering software. Bioinformatics (2004) 20(9):1453–4. 10.1093/bioinformatics/bth078
    • (2004) Bioinformatics , vol.20 , Issue.9 , pp. 1453-1454
    • de Hoon, M.J.1    Imoto, S.2    Nolan, J.3    Miyano, S.4
  • 46
    • 9444225935 scopus 로고    scopus 로고
    • Java Treeview-extensible visualization of microarray data
    • Saldanha AJ. Java Treeview-extensible visualization of microarray data. Bioinformatics (2004) 20(17):3246–8. 10.1093/bioinformatics/bth349
    • (2004) Bioinformatics , vol.20 , Issue.17 , pp. 3246-3248
    • Saldanha, A.J.1
  • 47
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang Daw, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 4(1):44–57. 10.1038/nprot.2008.211
    • (2009) Nat Protoc , vol.4 , Issue.1 , pp. 44-57
    • Huang, D.1    Sherman, B.T.2    Lempicki, R.A.3
  • 48
    • 0344464733 scopus 로고    scopus 로고
    • Gene expression dynamics inspector (GEDI): for integrative analysis of expression profiles
    • Eichler GS, Huang S, Ingber DE. Gene expression dynamics inspector (GEDI): for integrative analysis of expression profiles. Bioinformatics (2003) 19(17):2321–2.
    • (2003) Bioinformatics , vol.19 , Issue.17 , pp. 2321-2322
    • Eichler, G.S.1    Huang, S.2    Ingber, D.E.3
  • 49
    • 85017572339 scopus 로고    scopus 로고
    • Suppression of transforming growth factor-beta signaling delays cellular senescence and preserves the function of endothelial cells derived from human pluripotent stem cells
    • Bai H, Gao Y, Hoyle DL, Cheng T, Wang ZZ. Suppression of transforming growth factor-beta signaling delays cellular senescence and preserves the function of endothelial cells derived from human pluripotent stem cells. Stem Cells Transl Med (2017) 6(2):589–600. 10.5966/sctm.2016-0089
    • (2017) Stem Cells Transl Med , vol.6 , Issue.2 , pp. 589-600
    • Bai, H.1    Gao, Y.2    Hoyle, D.L.3    Cheng, T.4    Wang, Z.Z.5
  • 50
    • 3042733135 scopus 로고    scopus 로고
    • A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells
    • Park C, Afrikanova I, Chung YS, Zhang WJ, Arentson E, Fong Gh G, et al. A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development (2004) 131(11):2749–62. 10.1242/dev.01130
    • (2004) Development , vol.131 , Issue.11 , pp. 2749-2762
    • Park, C.1    Afrikanova, I.2    Chung, Y.S.3    Zhang, W.J.4    Arentson, E.5    Fong Gh, G.6
  • 51
    • 0041440927 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: An autocrine mechanism contributing to angiogenesis
    • Seghezzi G, Patel S, Ren CJ, Gualandris A, Pintucci G, Robbins ES, et al. Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: An autocrine mechanism contributing to angiogenesis. J Cell Biol (1998) 141(7):1659–73.
    • (1998) J Cell Biol , vol.141 , Issue.7 , pp. 1659-1673
    • Seghezzi, G.1    Patel, S.2    Ren, C.J.3    Gualandris, A.4    Pintucci, G.5    Robbins, E.S.6
  • 52
    • 0034597798 scopus 로고    scopus 로고
    • Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors
    • Yamashita J, Itoh H, Hirashima M, Ogawa M, Nishikawa S, Yurugi T, et al. Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature (2000) 408(6808):92–6. 10.1038/35040568
    • (2000) Nature , vol.408 , Issue.6808 , pp. 92-96
    • Yamashita, J.1    Itoh, H.2    Hirashima, M.3    Ogawa, M.4    Nishikawa, S.5    Yurugi, T.6
  • 53
    • 65549120788 scopus 로고    scopus 로고
    • Signaling hierarchy regulating human endothelial cell development
    • Kelly MA, Hirschi KK. Signaling hierarchy regulating human endothelial cell development. Arterioscler Thromb Vasc Biol (2009) 29(5):718–24. 10.1161/ATVBAHA.109.184200
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.5 , pp. 718-724
    • Kelly, M.A.1    Hirschi, K.K.2
  • 54
    • 0031451332 scopus 로고    scopus 로고
    • Expression cloning of a novel scavenger receptor from human endothelial cells
    • Adachi H, Tsujimoto M, Arai H, Inoue K. Expression cloning of a novel scavenger receptor from human endothelial cells. J Biol Chem (1997) 272(50):31217–20. 10.1074/jbc.272.50.31217
    • (1997) J Biol Chem , vol.272 , Issue.50 , pp. 31217-31220
    • Adachi, H.1    Tsujimoto, M.2    Arai, H.3    Inoue, K.4
  • 55
    • 84883165280 scopus 로고    scopus 로고
    • The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity
    • Ramirez-Ortiz ZG, Pendergraft WF, Prasad A, Byrne MH, Iram T, Blanchette CJ, et al. The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity. Nat Immunol (2013) 14(9):917–26. 10.1038/ni.2670
    • (2013) Nat Immunol , vol.14 , Issue.9 , pp. 917-926
    • Ramirez-Ortiz, Z.G.1    Pendergraft, W.F.2    Prasad, A.3    Byrne, M.H.4    Iram, T.5    Blanchette, C.J.6
  • 56
    • 3843116691 scopus 로고    scopus 로고
    • Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide
    • Tamura Y, Osuga J, Adachi H, Tozawa R, Takanezawa Y, Ohashi K, et al. Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide. J Biol Chem (2004) 279(30):30938–44. 10.1074/jbc.M313088200
    • (2004) J Biol Chem , vol.279 , Issue.30 , pp. 30938-30944
    • Tamura, Y.1    Osuga, J.2    Adachi, H.3    Tozawa, R.4    Takanezawa, Y.5    Ohashi, K.6
  • 58
    • 85041891903 scopus 로고    scopus 로고
    • MEIS1 regulates hemogenic endothelial generation, megakaryopoiesis, and thrombopoiesis in human pluripotent stem cells by targeting TAL1 and FLI1
    • Wang H, Liu C, Liu X, Wang M, Wu D, Gao J, et al. MEIS1 regulates hemogenic endothelial generation, megakaryopoiesis, and thrombopoiesis in human pluripotent stem cells by targeting TAL1 and FLI1. Stem Cell Reports (2018) 10(2):447–60. 10.1016/j.stemcr.2017.12.017
    • (2018) Stem Cell Reports , vol.10 , Issue.2 , pp. 447-460
    • Wang, H.1    Liu, C.2    Liu, X.3    Wang, M.4    Wu, D.5    Gao, J.6
  • 59
    • 33747196725 scopus 로고    scopus 로고
    • Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
    • Laslo P, Spooner CJ, Warmflash A, Lancki DW, Lee HJ, Sciammas R, et al. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell (2006) 126(4):755–66. 10.1016/j.cell.2006.06.052
    • (2006) Cell , vol.126 , Issue.4 , pp. 755-766
    • Laslo, P.1    Spooner, C.J.2    Warmflash, A.3    Lancki, D.W.4    Lee, H.J.5    Sciammas, R.6
  • 60
    • 58549117664 scopus 로고    scopus 로고
    • Transcriptional regulatory networks in haematopoiesis
    • Miranda-Saavedra D, Göttgens B. Transcriptional regulatory networks in haematopoiesis. Curr Opin Genet Dev (2008) 18(6):530–5. 10.1016/j.gde.2008.09.001
    • (2008) Curr Opin Genet Dev , vol.18 , Issue.6 , pp. 530-535
    • Miranda-Saavedra, D.1    Göttgens, B.2
  • 61
    • 0033587755 scopus 로고    scopus 로고
    • Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1
    • Zhang P, Behre G, Pan J, Iwama A, Wara-Aswapati N, Radomska HS, et al. Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. Proc Natl Acad Sci USA (1999) 96(15):8705–10. 10.1073/pnas.96.15.8705
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.15 , pp. 8705-8710
    • Zhang, P.1    Behre, G.2    Pan, J.3    Iwama, A.4    Wara-Aswapati, N.5    Radomska, H.S.6
  • 62
    • 85028473833 scopus 로고    scopus 로고
    • VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis
    • Chen J, Fu Y, Day DS, Sun Y, Wang S, Liang X, et al. VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis. Nat Commun (2017) 8(1):383–017. 10.1038/s41467-017-00405-x
    • (2017) Nat Commun , vol.8 , Issue.1 , pp. 383-017
    • Chen, J.1    Fu, Y.2    Day, D.S.3    Sun, Y.4    Wang, S.5    Liang, X.6
  • 63
    • 59649110012 scopus 로고    scopus 로고
    • Transcriptional control of endothelial cell development
    • de Val S, Black BL. Transcriptional control of endothelial cell development. Dev Cell (2009) 16(2):180–95. 10.1016/j.devcel.2009.01.014
    • (2009) Dev Cell , vol.16 , Issue.2 , pp. 180-195
    • de Val, S.1    Black, B.L.2
  • 64
    • 79959700169 scopus 로고    scopus 로고
    • Key transcriptional regulators of early vascular development
    • de Val S. Key transcriptional regulators of early vascular development. Arterioscler Thromb Vasc Biol (2011) 31(7):1469–75. 10.1161/ATVBAHA.110.221168
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , Issue.7 , pp. 1469-1475
    • de Val, S.1
  • 65
    • 85012118591 scopus 로고    scopus 로고
    • The molecular basis of endothelial cell plasticity
    • Dejana E, Hirschi KK, Simons M. The molecular basis of endothelial cell plasticity. Nat Commun (2017) 8:14361. 10.1038/ncomms14361
    • (2017) Nat Commun , vol.8
    • Dejana, E.1    Hirschi, K.K.2    Simons, M.3
  • 66
    • 84904489277 scopus 로고    scopus 로고
    • Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators
    • Elcheva I, Brok-Volchanskaya V, Kumar A, Liu P, Lee JH, Tong L, et al. Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators. Nat Commun (2014) 5:4372. 10.1038/ncomms5372
    • (2014) Nat Commun , vol.5
    • Elcheva, I.1    Brok-Volchanskaya, V.2    Kumar, A.3    Liu, P.4    Lee, J.H.5    Tong, L.6
  • 67
    • 85020201660 scopus 로고    scopus 로고
    • Dynamically and epigenetically coordinated GATA/ETS/SOX transcription factor expression is indispensable for endothelial cell differentiation
    • Kanki Y, Nakaki R, Shimamura T, Matsunaga T, Yamamizu K, Katayama S, et al. Dynamically and epigenetically coordinated GATA/ETS/SOX transcription factor expression is indispensable for endothelial cell differentiation. Nucleic Acids Res (2017) 45(8):4344–58. 10.1093/nar/gkx159
    • (2017) Nucleic Acids Res , vol.45 , Issue.8 , pp. 4344-4358
    • Kanki, Y.1    Nakaki, R.2    Shimamura, T.3    Matsunaga, T.4    Yamamizu, K.5    Katayama, S.6
  • 68
    • 84969931488 scopus 로고    scopus 로고
    • Regulation of endothelial homeostasis, vascular development and angiogenesis by the transcription factor ERG
    • Shah AV, Birdsey GM, Randi AM. Regulation of endothelial homeostasis, vascular development and angiogenesis by the transcription factor ERG. Vascul Pharmacol (2016) 86:3–13. 10.1016/j.vph.2016.05.003
    • (2016) Vascul Pharmacol , vol.86 , pp. 3-13
    • Shah, A.V.1    Birdsey, G.M.2    Randi, A.M.3
  • 69
    • 85006285022 scopus 로고    scopus 로고
    • Induced pluripotent stem cell technology: a decade of progress
    • Shi Y, Inoue H, Wu JC, Yamanaka S. Induced pluripotent stem cell technology: a decade of progress. Nat Rev Drug Discov (2017) 16(2):115–30. 10.1038/nrd.2016.245
    • (2017) Nat Rev Drug Discov , vol.16 , Issue.2 , pp. 115-130
    • Shi, Y.1    Inoue, H.2    Wu, J.C.3    Yamanaka, S.4
  • 70
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature (2002) 420(6916):629–35. 10.1038/nature01148
    • (2002) Nature , vol.420 , Issue.6916 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 71
    • 0042344706 scopus 로고    scopus 로고
    • Rho GTPases and the regulation of endothelial permeability
    • Wojciak-Stothard B, Ridley AJ. Rho GTPases and the regulation of endothelial permeability. Vascul Pharmacol (2002) 39(4-5):187–99. 10.1016/S1537-1891(03)00008-9
    • (2002) Vascul Pharmacol , vol.39 , Issue.4-5 , pp. 187-199
    • Wojciak-Stothard, B.1    Ridley, A.J.2
  • 72
    • 0032480888 scopus 로고    scopus 로고
    • Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
    • de Rooij J, Zwartkruis FJ, Verheijen MH, Cool RH, Nijman SM, Wittinghofer A, et al. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature (1998) 396(6710):474–7. 10.1038/24884
    • (1998) Nature , vol.396 , Issue.6710 , pp. 474-477
    • de Rooij, J.1    Zwartkruis, F.J.2    Verheijen, M.H.3    Cool, R.H.4    Nijman, S.M.5    Wittinghofer, A.6
  • 73
    • 14944377651 scopus 로고    scopus 로고
    • Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase
    • Cullere X, Shaw SK, Andersson L, Hirahashi J, Luscinskas FW, Mayadas TN. Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase. Blood (2005) 105(5):1950–5. 10.1182/blood-2004-05-1987
    • (2005) Blood , vol.105 , Issue.5 , pp. 1950-1955
    • Cullere, X.1    Shaw, S.K.2    Andersson, L.3    Hirahashi, J.4    Luscinskas, F.W.5    Mayadas, T.N.6
  • 74
    • 85029172642 scopus 로고    scopus 로고
    • The ROCK inhibitor, thiazovivin, inhibits human corneal endothelial‑to‑mesenchymal transition/epithelial‑to‑mesenchymal transition and increases ionic transporter expression
    • Wu Q, Ouyang C, Xie L, Ling Y, Huang T. The ROCK inhibitor, thiazovivin, inhibits human corneal endothelial‑to‑mesenchymal transition/epithelial‑to‑mesenchymal transition and increases ionic transporter expression. Int J Mol Med (2017) 40(4):1009–18. 10.3892/ijmm.2017.3103
    • (2017) Int J Mol Med , vol.40 , Issue.4 , pp. 1009-1018
    • Wu, Q.1    Ouyang, C.2    Xie, L.3    Ling, Y.4    Huang, T.5
  • 75
    • 3242757526 scopus 로고    scopus 로고
    • TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways
    • Nakagawa T, Li JH, Garcia G, Mu W, Piek E, Böttinger EP, et al. TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways. Kidney Int (2004) 66(2):605–13. 10.1111/j.1523-1755.2004.00780.x
    • (2004) Kidney Int , vol.66 , Issue.2 , pp. 605-613
    • Nakagawa, T.1    Li, J.H.2    Garcia, G.3    Mu, W.4    Piek, E.5    Böttinger, E.P.6
  • 76
    • 85023611906 scopus 로고    scopus 로고
    • Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells
    • Hogan NT, Whalen MB, Stolze LK, Hadeli NK, Lam MT, Springstead JR, et al. Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells. Elife (2017) 6:e22536. 10.7554/eLife.22536
    • (2017) Elife , vol.6
    • Hogan, N.T.1    Whalen, M.B.2    Stolze, L.K.3    Hadeli, N.K.4    Lam, M.T.5    Springstead, J.R.6
  • 77
    • 84890899156 scopus 로고    scopus 로고
    • Identification of transcription factors for lineage-specific ESC differentiation
    • Yamamizu K, Piao Y, Sharov AA, Zsiros V, Yu H, Nakazawa K, et al. Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports (2013) 1(6):545–59. 10.1016/j.stemcr.2013.10.006
    • (2013) Stem Cell Reports , vol.1 , Issue.6 , pp. 545-559
    • Yamamizu, K.1    Piao, Y.2    Sharov, A.A.3    Zsiros, V.4    Yu, H.5    Nakazawa, K.6
  • 78
    • 2642564628 scopus 로고    scopus 로고
    • Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation
    • Bohnsack BL, Lai L, Dolle P, Hirschi KK. Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation. Genes Dev (2004) 18(11):1345–58. 10.1101/gad.1184904
    • (2004) Genes Dev , vol.18 , Issue.11 , pp. 1345-1358
    • Bohnsack, B.L.1    Lai, L.2    Dolle, P.3    Hirschi, K.K.4
  • 79
    • 0026663415 scopus 로고
    • Effects of retinoids on endothelial cell proliferation, prostacyclin production and platelet aggregation
    • Lee JY, Mak CP, Wang BJ, Chang WC. Effects of retinoids on endothelial cell proliferation, prostacyclin production and platelet aggregation. J Dermatol Sci (1992) 3(3):157–62.
    • (1992) J Dermatol Sci , vol.3 , Issue.3 , pp. 157-162
    • Lee, J.Y.1    Mak, C.P.2    Wang, B.J.3    Chang, W.C.4
  • 80
    • 33847012234 scopus 로고    scopus 로고
    • All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of paracrine effects of endogenous vascular endothelial growth factor signaling
    • Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, et al. All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of paracrine effects of endogenous vascular endothelial growth factor signaling. Endocrinology (2007) 148(3):1412–23. 10.1210/en.2006-0900
    • (2007) Endocrinology , vol.148 , Issue.3 , pp. 1412-1423
    • Saito, A.1    Sugawara, A.2    Uruno, A.3    Kudo, M.4    Kagechika, H.5    Sato, Y.6
  • 81
    • 85029531732 scopus 로고    scopus 로고
    • The cAMP effectors PKA and epac activate endothelial NO synthase through PI3K/Akt pathway in human endothelial cells
    • García-Morales V, Luaces-Regueira M, Campos-Toimil M. The cAMP effectors PKA and epac activate endothelial NO synthase through PI3K/Akt pathway in human endothelial cells. Biochem Pharmacol (2017) 145:94–101. 10.1016/j.bcp.2017.09.004
    • (2017) Biochem Pharmacol , vol.145 , pp. 94-101
    • García-Morales, V.1    Luaces-Regueira, M.2    Campos-Toimil, M.3
  • 82
    • 0036842491 scopus 로고    scopus 로고
    • Smad2 mediates transforming growth factor-beta induction of endothelial nitric oxide synthase expression
    • Saura M, Zaragoza C, Cao W, Bao C, Rodríguez-Puyol M, Rodríguez-Puyol D, et al. Smad2 mediates transforming growth factor-beta induction of endothelial nitric oxide synthase expression. Circ Res (2002) 91(9):806–13. 10.1161/01.RES.0000040397.23817.E5
    • (2002) Circ Res , vol.91 , Issue.9 , pp. 806-813
    • Saura, M.1    Zaragoza, C.2    Cao, W.3    Bao, C.4    Rodríguez-Puyol, M.5    Rodríguez-Puyol, D.6
  • 83
    • 16244400050 scopus 로고    scopus 로고
    • TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    • James D, Levine AJ, Besser D, Hemmati-Brivanlou A. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development (2005) 132(6):1273–82. 10.1242/dev.01706
    • (2005) Development , vol.132 , Issue.6 , pp. 1273-1282
    • James, D.1    Levine, A.J.2    Besser, D.3    Hemmati-Brivanlou, A.4
  • 84
    • 84922808247 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor β (TGF-β) signaling can substitute for Oct4 protein in reprogramming and maintain pluripotency
    • Tan F, Qian C, Tang K, Abd-Allah SM, Jing N. Inhibition of transforming growth factor β (TGF-β) signaling can substitute for Oct4 protein in reprogramming and maintain pluripotency. J Biol Chem (2015) 290(7):4500–11. 10.1074/jbc.M114.609016
    • (2015) J Biol Chem , vol.290 , Issue.7 , pp. 4500-4511
    • Tan, F.1    Qian, C.2    Tang, K.3    Abd-Allah, S.M.4    Jing, N.5
  • 85
    • 27644486756 scopus 로고    scopus 로고
    • Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells
    • Vallier L, Alexander M, Pedersen RA. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. J Cell Sci (2005) 118(Pt 19):4495–509. 10.1242/jcs.02553
    • (2005) J Cell Sci , vol.118 , pp. 4495-4509
    • Vallier, L.1    Alexander, M.2    Pedersen, R.A.3
  • 86
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    • Inman GJ, Nicolás FJ, Callahan JF, Harling JD, Gaster LM, Reith AD, et al. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol (2002) 62(1):65–74. 10.1124/mol.62.1.65
    • (2002) Mol Pharmacol , vol.62 , Issue.1 , pp. 65-74
    • Inman, G.J.1    Nicolás, F.J.2    Callahan, J.F.3    Harling, J.D.4    Gaster, L.M.5    Reith, A.D.6
  • 87
    • 0242330126 scopus 로고    scopus 로고
    • Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling
    • Goumans MJ, Valdimarsdottir G, Itoh S, Lebrin F, Larsson J, Mummery C, et al. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. Mol Cell (2003) 12(4):817–28. 10.1016/S1097-2765(03)00386-1
    • (2003) Mol Cell , vol.12 , Issue.4 , pp. 817-828
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3    Lebrin, F.4    Larsson, J.5    Mummery, C.6
  • 88
    • 84868138400 scopus 로고    scopus 로고
    • Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression
    • Ginsberg M, James D, Ding BS, Nolan D, Geng F, Butler JM, et al. Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression. Cell (2012) 151(3):559–75. 10.1016/j.cell.2012.09.032
    • (2012) Cell , vol.151 , Issue.3 , pp. 559-575
    • Ginsberg, M.1    James, D.2    Ding, B.S.3    Nolan, D.4    Geng, F.5    Butler, J.M.6
  • 89
    • 79958079250 scopus 로고    scopus 로고
    • Differentiation of an embryonic stem cell to hemogenic endothelium by defined factors: essential role of bone morphogenetic protein 4
    • Chiang PM, Wong PC. Differentiation of an embryonic stem cell to hemogenic endothelium by defined factors: essential role of bone morphogenetic protein 4. Development (2011) 138(13):2833–43. 10.1242/dev.061440
    • (2011) Development , vol.138 , Issue.13 , pp. 2833-2843
    • Chiang, P.M.1    Wong, P.C.2
  • 90
    • 37549020639 scopus 로고    scopus 로고
    • Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood
    • Nostro MC, Cheng X, Keller GM, Gadue P. Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood. Cell Stem Cell (2008) 2(1):60–71. 10.1016/j.stem.2007.10.011
    • (2008) Cell Stem Cell , vol.2 , Issue.1 , pp. 60-71
    • Nostro, M.C.1    Cheng, X.2    Keller, G.M.3    Gadue, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.