메뉴 건너뛰기




Volumn , Issue , 2009, Pages 103-116

DNA methylation and human diseases: An overview

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85050922469     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (2)

References (82)
  • 1
    • 32844459336 scopus 로고    scopus 로고
    • The polycomb group protein ezh2 directly controls dna méthylation
    • Viré E, Brenner C, Deplus R et al. The polycomb group protein EZH2 directly controls DNA méthylation. Nature 2006; 439:871-874.
    • (2006) Nature , vol.439 , pp. 871-874
    • Viré, E.1    Brenner, C.2    Deplus, R.3
  • 2
    • 27744566944 scopus 로고    scopus 로고
    • Lsh, a guardian of heterochromatin at repeat elements
    • Muegge K. Lsh, a guardian of Heterochromatin at repeat elements. Biochem Cell Biol 2005; 83:548-54.
    • (2005) Biochem Cell Biol , vol.83 , pp. 548-554
    • Muegge, K.1
  • 3
    • 47849083984 scopus 로고    scopus 로고
    • Epigenetic interplay between histone modifications and dna méthylation in gene silencing
    • Vaissière X Sawan C, Herceg Z. Epigenetic interplay between histone modifications and DNA méthylation in gene silencing. Mutât Res 2008; 659:40-48.
    • (2008) Mutât Res , vol.659 , pp. 40-48
    • Vaissière X Sawan, C.1    Herceg, Z.2
  • 4
    • 40449104358 scopus 로고    scopus 로고
    • Transient cyclical méthylation of promoter dna
    • Kangaspeska S, Stride B, Métivicr R et al. Transient cyclical méthylation of promoter DNA. Nature 2008; 452:112-115.
    • (2008) Nature , vol.452 , pp. 112-115
    • Kangaspeska, S.1    Stride, B.2    Métivicr, R.3
  • 5
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Rcik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 2007; 447:425-432.
    • (2007) Nature , vol.447 , pp. 425-432
    • Rcik, W.1
  • 6
    • 38649127832 scopus 로고    scopus 로고
    • Loss of spermatogonia and wide-spread dna méthylation defects in newborn male mice deficient in dnmt3l
    • La Salle S, Oakes CC, Neaga OR et al. Loss of spermatogonia and wide-spread DNA méthylation defects in newborn male mice deficient in DNMT3L. BMC Dev Biol 2007; 7:104.
    • (2007) BMC Dev Biol , vol.7 , pp. 104
    • La Salle, S.1    Oakes, C.C.2    Neaga, O.R.3
  • 7
    • 0031889033 scopus 로고    scopus 로고
    • Sex-specific exons control dna methyltransferase in mammalian germ cells
    • Mertineit C. Yoder JA, Taketo T et al Sex-specific exons control DNA methyltransferase in mammalian germ cells. Development 1998; 125:889-897.
    • (1998) Development , vol.125 , pp. 889-897
    • Mertineit, C.1    Yoder, J.A.2    Taketo, T.3
  • 8
    • 33746069681 scopus 로고    scopus 로고
    • Dosage compensation in mammals: Fine-tuning the expression of the x chromosome
    • Heard E, Disteche CM. Dosage compensation in mammals: fine-tuning the expression of the X chromosome. Genes Dev 2006; 20:1848-1867.
    • (2006) Genes Dev , vol.20 , pp. 1848-1867
    • Heard, E.1    Disteche, C.M.2
  • 9
    • 45549098196 scopus 로고    scopus 로고
    • Intersection of the rna interference and x-inactivation pathways
    • Ogawa Y, Sun BK, Lee JT. Intersection of the RNA interference and X-inactivation pathways. Science2008; 320:1336-1341.
    • (2008) Science , vol.320 , pp. 1336-1341
    • Ogawa, Y.1    Sun, B.K.2    Lee, J.T.3
  • 10
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine mcthyltransferases
    • Goll MG, Bestor TH. Eukaryotic cytosine mcthyltransferases. Annu Rev Biochem 2005; 74:481-514.
    • (2005) Annu Rev Biochem , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 11
    • 33645284007 scopus 로고    scopus 로고
    • Méthylation of endogenous human retroelements in health and disease
    • Schulz WA, Steinhoff C, Florl AR. Méthylation of endogenous human retroelements in health and disease. Curr Topics Microbiol Immunol 2006; 310:211-250.
    • (2006) Curr Topics Microbiol Immunol , vol.310 , pp. 211-250
    • Schulz, W.A.1    Steinhoff, C.2    Florl, A.R.3
  • 12
    • 0346373737 scopus 로고    scopus 로고
    • Transcriptional regulation of the human line-1 retrotransposon l1.2b
    • Steinhoff C, Schulz WA. Transcriptional regulation of the human LINE-1 retrotransposon L1.2B. Mol Genet Genomics 2003; 270:394-402.
    • (2003) Mol Genet Genomics , vol.270 , pp. 394-402
    • Steinhoff, C.1    Schulz, W.A.2
  • 13
    • 33846581497 scopus 로고    scopus 로고
    • Loss of imprinting and cancer
    • Jelinic P, Shaw P. Loss of imprinting and cancer. J Pathol 2007; 211:261-268.
    • (2007) J Pathol , vol.211 , pp. 261-268
    • Jelinic, P.1    Shaw, P.2
  • 14
    • 34848911647 scopus 로고    scopus 로고
    • Dna méthylation: The nuts and bolts of repression
    • Miranda TB, Jones PA. DNA méthylation: the nuts and bolts of repression. J Cell Physiol 2007; 213:384-390.
    • (2007) J Cell Physiol , vol.213 , pp. 384-390
    • Miranda, T.B.1    Jones, P.A.2
  • 15
    • 34047116826 scopus 로고    scopus 로고
    • Distribution, silencing potential and evolutionary impact of promoter dna méthylation in the human genome
    • Weber M, Hellmann I, Stadler MB et al. Distribution, silencing potential and evolutionary impact of promoter DNA méthylation in the human genome. Nat Genet 2007; 39442-39453.
    • (2007) Nat Genet , pp. 39442-39453
    • Weber, M.1    Hellmann, I.2    Stadler, M.B.3
  • 16
    • 45349086923 scopus 로고    scopus 로고
    • Global mapping of dna méthylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
    • Farthing CR, Fiez G, Ng RK et al Global mapping of DNA méthylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet 2008; 4:e1000116.
    • (2008) Plos Genet , vol.4 , pp. e1000116
    • Farthing, C.R.1    Fiez, G.2    Ng, R.K.3
  • 17
    • 51649129596 scopus 로고    scopus 로고
    • Lineage-specific polycomb targets and de novo dna méthylation define restriction and potential of neuronal progenitors
    • Mohn F, Weber M, Rebhan M et al Lineage-specific polycomb targets and de novo DNA méthylation define restriction and potential of neuronal progenitors. Mol Cell 2008; 30:755-66.
    • (2008) Mol Cell , vol.30 , pp. 755-766
    • Mohn, F.1    Weber, M.2    Rebhan, M.3
  • 18
    • 57349163599 scopus 로고    scopus 로고
    • Relationship of sncg, s100a4, s100a9 and lcn2 gene expression and dna méthylation in bladder cancer
    • Dokun OY, Florl AR, Seifert HH et al. Relationship of SNCG, S100A4, S100A9 and LCN2 gene expression and DNA méthylation in bladder cancer. Int J Cancer 2008; 123:2798-2807.
    • (2008) Int J Cancer , vol.123 , pp. 2798-2807
    • Dokun, O.Y.1    Florl, A.R.2    Seifert, H.H.3
  • 19
    • 0142216231 scopus 로고    scopus 로고
    • The icf syndrome, a dna methyltransferase 3b deficiency and immunodeficiency disease
    • Ehrlich M. The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease. Clin Immunol 2003; 109:17-28.
    • (2003) Clin Immunol , vol.109 , pp. 17-28
    • Ehrlich, M.1
  • 20
    • 22844457491 scopus 로고    scopus 로고
    • Dna méthylation and human disease
    • Robertson KD. DNA méthylation and human disease. Nat Rev Genet 2005; 6:597-610.
    • (2005) Nat Rev Genet , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 21
    • 39749152283 scopus 로고    scopus 로고
    • Dna methyltransferase 3b (Dnmt3b) mutations in icf syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogcncsis and immune function
    • Jin B, Tao Q, Peng J et al DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogcncsis and immune function. Hum Mol Genet 2008; 17:690-709.
    • (2008) Hum Mol Genet , vol.17 , pp. 690-709
    • Jin, B.1    Tao, Q.2    Peng, J.3
  • 22
    • 20144384429 scopus 로고    scopus 로고
    • Dna méthylation 40 years later: Its role in human health and disease
    • Scarano MI, Strazzullo M, Matarazzo MR et al. DNA méthylation 40 years later: its role in human health and disease. J Cell Physiol 2005: 204:21-35.
    • (2005) J Cell Physiol , vol.204 , pp. 21-35
    • Scarano, M.I.1    Strazzullo, M.2    Matarazzo, M.R.3
  • 23
    • 33646473832 scopus 로고    scopus 로고
    • Loss of atrx affects trophoblast development and the pattern of x-inactivarion in cxtraembryonic tissues
    • Garrick D, Sharpe JA, Arkell R et al Loss of atrx affects trophoblast development and the pattern of X-inactivarion in cxtraembryonic tissues. PLoS Genet 2006: 2:e58.
    • (2006) Plos Genet , vol.2 , pp. e58
    • Garrick, D.1    Sharpe, J.A.2    Arkell, R.3
  • 25
    • 33646893456 scopus 로고    scopus 로고
    • Molecular genetics of rett syndrome: When dna méthylation goes unrecognized
    • Bienvenu T, Chelly J. Molecular genetics of Rett syndrome: when DNA méthylation goes unrecognized. Nat Rev Genet 2006; 7:415-426.
    • (2006) Nat Rev Genet , vol.7 , pp. 415-426
    • Bienvenu, T.1    Chelly, J.2
  • 26
    • 31444434393 scopus 로고    scopus 로고
    • The disease progression of mecp2 mutant mice is affected by the level of bdnf expression
    • Chang Q, Khare G, Dani V et al The disease progression of mecp2 Mutant mice is affected by the level of BDNF expression. Neuron 2006; 49:341-8.
    • (2006) Neuron , vol.49 , pp. 341-348
    • Chang, Q.1    Khare, G.2    Dani, V.3
  • 27
    • 34247097430 scopus 로고    scopus 로고
    • Molecular epigenctics of angelman syndrome
    • Lalande M, Calciano MA. Molecular epigenctics of Angelman syndrome. Cell Mol Life Sci 2007; 64:947-60.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 947-960
    • Lalande, M.1    Calciano, M.A.2
  • 28
    • 49449111926 scopus 로고    scopus 로고
    • Mechanisms of imprinting of the prader-willi/angelman region
    • Horsthemke B, Wagstaff J. Mechanisms of imprinting of the Prader-Willi/Angelman region. Am J Med Genet 2008; 146A:2041-2052.
    • (2008) Am J Med Genet , vol.146A , pp. 2041-2052
    • Horsthemke, B.1    Wagstaff, J.2
  • 29
    • 33644513754 scopus 로고    scopus 로고
    • Epimutation of the tndm locus and the beckwith-wiedemann syndrome centromceric locus in individuals with transient neonatal diabetes mellitus
    • Mackay DJ, Hahnemann JM, Boonen SE et al. Epimutation of the TNDM locus and the Beckwith-Wiedemann syndrome centromceric locus in individuals with transient neonatal diabetes mellitus. Hum Genet 2006; 119:179-184.
    • (2006) Hum Genet , vol.119 , pp. 179-184
    • Mackay, D.J.1    Hahnemann, J.M.2    Boonen, S.E.3
  • 30
    • 42449088201 scopus 로고    scopus 로고
    • Control of imprinting at the gnas cluster
    • Peters J, Williamson CM. Control of imprinting at the gnas cluster. Adv Exp Med Biol 2008; 626:16-26.
    • (2008) Adv Exp Med Biol , vol.626 , pp. 16-26
    • Peters, J.1    Williamson, C.M.2
  • 31
    • 0034639857 scopus 로고    scopus 로고
    • Understanding the molecular basis of fragile x syndrome
    • Jin P, Warren ST. Understanding the molecular basis of fragile X syndrome. Hum Mol Genet 2000; 9:901-908.
    • (2000) Hum Mol Genet , vol.9 , pp. 901-908
    • Jin, P.1    Warren, S.T.2
  • 32
    • 13844251804 scopus 로고    scopus 로고
    • The d4z4 repeat-mediated pathogenesis of facioscapulohumeral muscular dystrophy
    • van der Maarel SM, Frants RR. The D4Z4 repeat-mediated pathogenesis of facioscapulohumeral muscular dystrophy. Am J Hum Genet 2005; 76:375-386.
    • (2005) Am J Hum Genet , vol.76 , pp. 375-386
    • Van Der Maarel, S.M.1    Frants, R.R.2
  • 33
    • 42449109111 scopus 로고    scopus 로고
    • Epigenctics of a tandem dna repeat: Chromatin dnasel sensitivity and opposite méthylation changes in cancers
    • Tsumagari K, Qi L, Jackson K et al Epigenctics of a tandem DNA repeat: chromatin DNasel sensitivity and opposite méthylation changes in cancers. Nucleic Acids Res 2008; 36:2196-2207.
    • (2008) Nucleic Acids Res , vol.36 , pp. 2196-2207
    • Tsumagari, K.1    Qi, L.2    Jackson, K.3
  • 34
    • 49649107703 scopus 로고    scopus 로고
    • Dna méthylation controls foxp3 gene expression
    • Polansky JK, Kretschmer K, Freyer J et al DNA méthylation controls Foxp3 gene expression. Eur J Immunol 2008; 38:1654-63.
    • (2008) Eur J Immunol , vol.38 , pp. 1654-1663
    • Polansky, J.K.1    Kretschmer, K.2    Freyer, J.3
  • 35
    • 0030994167 scopus 로고    scopus 로고
    • Specific déméthylation of the cd4 gene during cd4 t-lymphocyte differentiation
    • Landolfi MM, Scollay R, Pames JR. Specific déméthylation of the CD4 gene during CD4 T-lymphocyte differentiation. Mol Immunol 1997; 34:53-61.
    • (1997) Mol Immunol , vol.34 , pp. 53-61
    • Landolfi, M.M.1    Scollay, R.2    Pames, J.R.3
  • 36
    • 14244260068 scopus 로고    scopus 로고
    • Dna méthylation and the expanding epigenerics of t-cell lineage commitment
    • Wilson CB, Makar KW, Shnyreva M et al. DNA méthylation and the expanding epigenerics of T-cell lineage commitment. Semin Immunol 2005; 17:105-119.
    • (2005) Semin Immunol , vol.17 , pp. 105-119
    • Wilson, C.B.1    Makar, K.W.2    Shnyreva, M.3
  • 37
    • 17444382745 scopus 로고    scopus 로고
    • Epigenetic control in the immune response
    • Reiner SL. Epigenetic control in the immune response. Hum Mol Genet 2005; 14:41-46.
    • (2005) Hum Mol Genet , vol.14 , pp. 41-46
    • Reiner, S.L.1
  • 38
    • 14244264313 scopus 로고    scopus 로고
    • Immunoglobulin locus silencing and allelic exclusion
    • Corcoran AE. Immunoglobulin locus silencing and allelic exclusion. Semin Immunol 2005; 17:141-154.
    • (2005) Semin Immunol , vol.17 , pp. 141-154
    • Corcoran, A.E.1
  • 39
    • 40449117475 scopus 로고    scopus 로고
    • Lineage-specific transition of histone signatures in the killer cell fg-like receptor locus from hematopoietic progenitor to nk cells
    • Santourlidis S, Graffinann N, Christ J et al. Lineage-specific transition of histone signatures in the killer cell Fg-like receptor locus from hematopoietic progenitor to NK cells. J Immunol 2008; 180:418-25.
    • (2008) J Immunol , vol.180 , pp. 418-425
    • Santourlidis, S.1    Graffinann, N.2    Christ, J.3
  • 40
    • 55849109584 scopus 로고    scopus 로고
    • The epigenctics of rrna genes: From molecular to chromosome biology
    • McStay B, Grummt I. The epigenctics of rRNA genes: from molecular to chromosome biology. Annu Rev Cell Dev Biol 2008; 24:131-157.
    • (2008) Annu Rev Cell Dev Biol , vol.24 , pp. 131-157
    • McStay, B.1    Grummt, I.2
  • 41
    • 42649095663 scopus 로고    scopus 로고
    • Epigenctics in human autoimmunity. Epigenctics in autoimmunity—dna méthylation in systemic lupus erythematosus and beyond
    • Strickland FM, Richardson BC. Epigenctics in human autoimmunity. Epigenctics in autoimmunity—DNA méthylation in systemic lupus erythematosus and beyond. Autoimmunity 2008; 41:278-286.
    • (2008) Autoimmunity , vol.41 , pp. 278-286
    • Strickland, F.M.1    Richardson, B.C.2
  • 42
    • 28844497663 scopus 로고    scopus 로고
    • Procainamide is a specific inhibitor of dna methyltransferase 1
    • Lee BH, Yegnasubramanian S, Lin X et al Procainamide is a specific inhibitor of DNA methyltransferase 1. J Biol Chem 2005; 280:40749-40756.
    • (2005) J Biol Chem , vol.280 , pp. 40749-40756
    • Lee, B.H.1    Yegnasubramanian, S.2    Lin, X.3
  • 44
    • 42649106519 scopus 로고    scopus 로고
    • Molecular mimicry and immunomodulation by the hres-1 endogenous retrovirus in sle
    • Perl A, Nagy G, Koncz A et al Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE. Autoimmunity 2008; 41:287-297.
    • (2008) Autoimmunity , vol.41 , pp. 287-297
    • Perl, A.1    Nagy, G.2    Koncz, A.3
  • 45
    • 48549088455 scopus 로고    scopus 로고
    • Antimicrobial peptides and sclf-dna in autoimmune skin inflammation
    • Gilliet M, Lande R. Antimicrobial peptides and sclf-DNA in autoimmune skin inflammation. Curr Opin Immunol 2008; 20:401-407.
    • (2008) Curr Opin Immunol , vol.20 , pp. 401-407
    • Gilliet, M.1    Lande, R.2
  • 46
    • 34548431318 scopus 로고    scopus 로고
    • Naturally occurring nucleoside modifications suppress the immunostimulatory activity of rna: Implication for therapeutic rna development
    • Kariko K, Wcissrnali D. Naturally occurring nucleoside modifications suppress the immunostimulatory activity of RNA: implication for therapeutic RNA development. Curr Opin Drug Discov Devel 2007; 10:523-532.
    • (2007) Curr Opin Drug Discov Devel , vol.10 , pp. 523-532
    • Kariko, K.1    Wcissrnali, D.2
  • 47
    • 33748349409 scopus 로고    scopus 로고
    • Significance of hypcrhomocysteincmia
    • Herrmann W. Significance of hypcrhomocysteincmia. Clin Lab 2006; 52:367-374.
    • (2006) Clin Lab , vol.52 , pp. 367-374
    • Herrmann, W.1
  • 48
    • 85056956199 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase c677t mutation, plasma homocysteine and folate in subjects from northern italy with or without angiographically documented severe coronary atherosclerotic disease: Evidence for an important genetic-environmental interaction
    • Girelli D, Friso S, Trabetti E et al. Methylenetetrahydrofolate reductase C677T mutation, plasma homocysteine and folate in subjects from northern Italy with or without angiographically documented severe coronary atherosclerotic disease: evidence for an important genetic-environmental interaction. Blood 1999; 93:1118-1120.
    • (1999) Blood , vol.93 , pp. 1118-1120
    • Girelli, D.1    Friso, S.2    Trabetti, E.3
  • 49
    • 17444416760 scopus 로고    scopus 로고
    • The impact of metabolism on dna méthylation
    • Ulrcy CL, Liu L, Andrews LG et al The impact of metabolism on DNA méthylation. Hum Mol Genet2005; 14:R139-147.
    • (2005) Hum Mol Genet , vol.14 , pp. R139-R147
    • Ulrcy, C.L.1    Liu, L.2    Andrews, L.G.3
  • 51
    • 0036326660 scopus 로고    scopus 로고
    • Elevation in s-adcnosylhomocystcine and dna hypomethylation: potential epigenetic mechanism for homocysteine-related pathology
    • James SJ, Mclnyk S, Pogribna M et al Elevation in S-adcnosylhomocystcine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology. J Nutr 2002; 132:2361S-2366S.
    • (2002) J Nutr , vol.132 , pp. 2361S-2366S
    • James, S.J.1    McLnyk, S.2    Pogribna, M.3
  • 52
    • 27744467306 scopus 로고    scopus 로고
    • Interactions between folate and aging for carcinogenesis
    • Choi SW, Friso S. Interactions between folate and aging for carcinogenesis. Clin Chcm Lab Med 2005; 43:1151-1157.
    • (2005) Clin Chcm Lab Med , vol.43 , pp. 1151-1157
    • Choi, S.W.1    Friso, S.2
  • 53
    • 12444279964 scopus 로고    scopus 로고
    • Treatment of depression: Time to consider folic acid and vitamin b12
    • Coppen A, Bolander-Gouaille C. Treatment of depression: time to consider folic acid and vitamin B12. J Psychopharmacol 2005; 19:59-65.
    • (2005) J Psychopharmacol , vol.19 , pp. 59-65
    • Coppen, A.1    Bolander-Gouaille, C.2
  • 54
    • 17444417521 scopus 로고    scopus 로고
    • Cancer epigenetics
    • Laird PW. Cancer epigenetics. Hum Mol Genet 2005: 14:R65-76.
    • (2005) Hum Mol Genet , vol.14 , pp. R65-R76
    • Laird, P.W.1
  • 55
    • 34547792388 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer: The dna hypermethylome
    • Esteller M. Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum Mol Genet 2007; 16:R50-59.
    • (2007) Hum Mol Genet , vol.16 , pp. R50-R59
    • Esteller, M.1
  • 56
    • 33847065486 scopus 로고    scopus 로고
    • The epigcnomics of cancer
    • Jones PA, Baylin SB. The epigcnomics of cancer. Cell 2007; 128:683-692.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 57
    • 43949136445 scopus 로고    scopus 로고
    • Modes of action of the dna methyltransforase inhibitors azacytidine and decitabine
    • Stresemann C, Lyko F. Modes of action of the DNA methyltransforase inhibitors azacytidine and decitabine. Int J Cancer 2008; 123:8-13.
    • (2008) Int J Cancer , vol.123 , pp. 8-13
    • Stresemann, C.1    Lyko, F.2
  • 58
    • 18144415066 scopus 로고    scopus 로고
    • Chromatin inactivation precedes de novo dna méthylation during the progressive epigenetic silencing of the rassf1a promoter
    • Strunnikova M, Schagdarsurengin U, Kehlen A et al. Chromatin inactivation precedes de novo DNA méthylation during the progressive epigenetic silencing of the RASSF1A promoter. Mol Cell Biol 2005; 25:3923-3933.
    • (2005) Mol Cell Biol , vol.25 , pp. 3923-3933
    • Strunnikova, M.1    Schagdarsurengin, U.2    Kehlen, A.3
  • 59
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    • Park IK, Qian D, Kiel M et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003; 423:302-305.
    • (2003) Nature , vol.423 , pp. 302-305
    • Park, I.K.1    Qian, D.2    Kiel, M.3
  • 60
    • 33846569960 scopus 로고    scopus 로고
    • A stem cell-like chromatin pattern may predispose tumor suppressor genes to dna hyperméthylation and heritable silencing
    • Ohm JE, McGarvey KM, Yu X et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hyperméthylation and heritable silencing. Nat Genet 2007; 39:237-242.
    • (2007) Nat Genet , vol.39 , pp. 237-242
    • Ohm, J.E.1    McGarvey, K.M.2    Yu, X.3
  • 61
    • 33846649587 scopus 로고    scopus 로고
    • Polycomb-mediatcd méthylation on lys27 of histone h3 premarks genes for de novo méthylation in cancer
    • Schlesinger Y, Straussman R, Keshet I et al. Polycomb-mediatcd méthylation on Lys27 of histone H3 premarks genes for de novo méthylation in cancer. Nat Genet 2007; 39:232-236.
    • (2007) Nat Genet , vol.39 , pp. 232-236
    • Schlesinger, Y.1    Straussman, R.2    Keshet, I.3
  • 62
    • 24744471011 scopus 로고    scopus 로고
    • Causes and consequences of dna hypomethylation in human cancer
    • Hoffinann MJ, Schulz WA. Causes and consequences of DNA hypomethylation in human cancer. Biochem Cell Biol 2005; 83:296-321.
    • (2005) Biochem Cell Biol , vol.83 , pp. 296-321
    • Hoffinann, M.J.1    Schulz, W.A.2
  • 63
    • 39449103319 scopus 로고    scopus 로고
    • Genome-wide tracking of unmcthylated dna alu repeats in normal and cancer cells
    • Rodriguez J, Vives L, Jordà M et al. Genome-wide tracking of unmcthylated DNA Alu repeats in normal and cancer cells. Nucleic Acids Res 2008; 36:770-784.
    • (2008) Nucleic Acids Res , vol.36 , pp. 770-784
    • Rodriguez, J.1    Vives, L.2    Jordà, M.3
  • 64
    • 10344260184 scopus 로고    scopus 로고
    • Cpg island methylator phenotype in cancer
    • Issa JP. CpG island methylator phenotype in cancer. Nat Rev Cancer 2004; 4:988-993.
    • (2004) Nat Rev Cancer , vol.4 , pp. 988-993
    • Issa, J.P.1
  • 65
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • Jass JR. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 2007; 50:113-130.
    • (2007) Histopathology , vol.50 , pp. 113-130
    • Jass, J.R.1
  • 66
    • 4644329189 scopus 로고    scopus 로고
    • Coordinate hyperméthylation at specific sites in prostate carcinoma precedes line-1 hypomethylation
    • Florl AR, Steinhoff C, Midler M et al. Coordinate hyperméthylation at specific sites in prostate carcinoma precedes LINE-1 hypomethylation. Brit J Cancer 2004; 91:985-994.
    • (2004) Brit J Cancer , vol.91 , pp. 985-994
    • Florl, A.R.1    Steinhoff, C.2    Midler, M.3
  • 67
    • 38049164130 scopus 로고    scopus 로고
    • Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice
    • Howard G, Eiges R, Gaudet F et al Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice. Oncogene 2008; 27:404-408.
    • (2008) Oncogene , vol.27 , pp. 404-408
    • Howard, G.1    Eiges, R.2    Gaudet, F.3
  • 68
    • 0036613432 scopus 로고    scopus 로고
    • Role for dna méthylation in the control of cell type specific maspin expression
    • Futscher BW, Oshiro MM, Wozniak RJ et al Role for DNA méthylation in the control of cell type specific maspin expression. Nat Genet 2002; 31:175-179.
    • (2002) Nat Genet , vol.31 , pp. 175-179
    • Futscher, B.W.1    Oshiro, M.M.2    Wozniak, R.J.3
  • 69
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF et al Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005; 122:947-956.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 70
    • 37549015214 scopus 로고    scopus 로고
    • Synergistic function of dna methyltransferases dnmt3a and dnmt3b in the méthylation of oct4 and nanog
    • Li JY, Pu MT, Hirasawa R et al Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the Méthylation of Oct4 and Nanog. Mol Cell Biol 2007; 27:8748-8759.
    • (2007) Mol Cell Biol , vol.27 , pp. 8748-8759
    • Li, J.Y.1    Pu, M.T.2    Hirasawa, R.3
  • 71
    • 34249275353 scopus 로고    scopus 로고
    • Phenotypic plasticity and the epigenetics of human disease
    • Feinberg AP. Phenotypic plasticity and the epigenetics of human disease. Nature 2007; 447:433-440.
    • (2007) Nature , vol.447 , pp. 433-440
    • Feinberg, A.P.1
  • 72
    • 16344389423 scopus 로고    scopus 로고
    • The tumor suppressor rassf1a in human carcinogenesis: an update
    • Dammann R, Schagdarsurengin U, Seidel C et al. The tumor suppressor RASSF1A in human carcinogenesis: an update. Histol Histopathol 2005; 20:645-663.
    • (2005) Histol Histopathol , vol.20 , pp. 645-663
    • Dammann, R.1    Schagdarsurengin, U.2    Seidel, C.3
  • 73
    • 33751186134 scopus 로고    scopus 로고
    • Dna méthylation alterations in urothelial carcinoma
    • Neuhausen A, Florl AR, Grimm MO et al DNA méthylation alterations in urothelial carcinoma. Cancer Biol Hier 2006; 8:993-1001.
    • (2006) Cancer Biol Hier , vol.8 , pp. 993-1001
    • Neuhausen, A.1    Florl, A.R.2    Grimm, M.O.3
  • 74
    • 25144518262 scopus 로고    scopus 로고
    • Mgmt promoter méthylation and field defect in sporadic colorectal cancer
    • Shen L, Kondo Y, Rosner GL et al MGMT promoter méthylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst 2005; 97:1330-1338.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1330-1338
    • Shen, L.1    Kondo, Y.2    Rosner, G.L.3
  • 75
    • 41149090082 scopus 로고    scopus 로고
    • Dna méthylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons
    • Siegmund KD, Connor CM, Campan M et al. DNA méthylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS ONE 2007; 2:e895.
    • (2007) Plos ONE , vol.2 , pp. e895
    • Siegmund, K.D.1    Connor, C.M.2    Campan, M.3
  • 76
    • 0032845215 scopus 로고    scopus 로고
    • Aging, dna méthylation and cancer
    • Issa JP. Aging, DNA méthylation and cancer. Crit Rev Oncol Hematol 1999; 32:31-43.
    • (1999) Crit Rev Oncol Hematol , vol.32 , pp. 31-43
    • Issa, J.P.1
  • 77
    • 33748803347 scopus 로고    scopus 로고
    • Expression profiling identifies three pathways altered in cellular immortalization: Interferon, cell cycle and cytoskeleton
    • Fridman AL, Tang L, Kulacva OI et al Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle and cytoskeleton. J Gerontol A Biol Sci Med Sci 2006; 61:879-889.
    • (2006) J Gerontol a Biol Sci Med Sci , vol.61 , pp. 879-889
    • Fridman, A.L.1    Tang, L.2    Kulacva, O.I.3
  • 78
    • 33847236985 scopus 로고    scopus 로고
    • Factor interaction analysis for chromosome 8 and dna méthylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
    • Schulz WA, Alcxa A, Jung V et al. Factor interaction analysis for chromosome 8 and DNA méthylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer. Mol Cancer 2007; 6:14.
    • (2007) Mol Cancer , vol.6 , pp. 14
    • Schulz, W.A.1    Alcxa, A.2    Jung, V.3
  • 79
    • 21644445383 scopus 로고    scopus 로고
    • A méthylation profile of in vitro immortalized human cell lines
    • Liu L, Zhang J, Bates S et al A méthylation profile of in vitro immortalized human cell lines. Int J Oneok2005; 26:275-285.
    • (2005) Int J Oneok , vol.26 , pp. 275-285
    • Liu, L.1    Zhang, J.2    Bates, S.3
  • 80
    • 43749098985 scopus 로고    scopus 로고
    • Dna méthylation landscapes: Provocative insights from epigenomics
    • Suzuki MM, Bird A. DNA méthylation landscapes: provocative insights from epigenomics. Nat Rev Genet2008; 9:465-476.
    • (2008) Nat Rev Genet , vol.9 , pp. 465-476
    • Suzuki, M.M.1    Bird, A.2
  • 81
    • 41149142015 scopus 로고    scopus 로고
    • Epigenetics and complex disease: From etiology to new therapeutics
    • Ptak C, Pctronis A. Epigenetics and complex disease: from etiology to new therapeutics. Annu Rev Pharmacol Toxicol 2008; 48:257-276.
    • (2008) Annu Rev Pharmacol Toxicol , vol.48 , pp. 257-276
    • Ptak, C.1    Pctronis, A.2
  • 82
    • 0012959217 scopus 로고    scopus 로고
    • Aberrant dna méthylation in cancer: Potential clinical interventions
    • Strathdee G, Brown R. Aberrant DNA méthylation in cancer: potential clinical interventions. Expert Rev Mol Med 2002; 4:10-17.
    • (2002) Expert Rev Mol Med , vol.4 , pp. 10-17
    • Strathdee, G.1    Brown, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.