In vivo knockdown of the herpes simplex virus 1 latency-associated transcript reduces reactivation from latency

Journal of Virology

Volumn 92, Issue 16, 2018, Pages

  Watson, Zachary L ^a   Washington, Shannan D ^b   Phelan, Dane M ^a   Lewin, Alfred S ^a   Tuli, Sonal S ^a   Schultz, Gregory S ^a   Neumann, Donna M ^b   Bloom, David C ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gene therapy; Latency; LncRNA; Reactivation; Ribozymes

Indexed keywords

ADENO ASSOCIATED VIRUS VECTOR; HAMMERHEAD RIBOZYME; LATENCY ASSOCIATED TRANSCRIPT PROTEIN; LONG UNTRANSLATED RNA; UNCLASSIFIED DRUG; VIRUS RNA; RIBOZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; HERPES SIMPLEX KERATITIS; HUMAN ALPHAHERPESVIRUS 1; IN VIVO STUDY; LATENT VIRUS INFECTION; LEPORIDAE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RECURRENT INFECTION; VIRAL GENE DELIVERY SYSTEM; VIRUS INHIBITION; VIRUS LATENCY; VIRUS REACTIVATION; ANIMAL; CELL CULTURE; DEPENDOPARVOVIRUS; GENE EXPRESSION REGULATION; GENE VECTOR; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHYSIOLOGY; VIROLOGY; VIRUS ACTIVATION;

ANIMALS; CELLS, CULTURED; DEPENDOVIRUS; GENE EXPRESSION REGULATION, VIRAL; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; NEURONS; RABBITS; RNA, CATALYTIC; RNA, LONG NONCODING; RNA, VIRAL; TRANSCRIPTION, GENETIC; VIRUS ACTIVATION; VIRUS LATENCY;

EID: 85050829579     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00812-18     Document Type: Article

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