Enhancement of bradykinin-induced relaxation by focal brain ischemia in the rat middle cerebral artery: Receptor expression upregulation and activation of multiple pathways

PLoS ONE

Volumn 13, Issue 6, 2018, Pages

  Li, Youhai ^a,b   Lapina, Natalia ^a,c   Weinzierl, Nina ^a   Schilling, Lothar ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c Lytech Co   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; BRADYKININ B1 RECEPTOR; BRADYKININ B2 RECEPTOR; GUANYLATE CYCLASE; MESSENGER RNA; NITRIC OXIDE; BRADYKININ RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HYPERPOLARIZATION; MALE; MIDDLE CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; UPREGULATION; VASOMOTOR REFLEX; ANIMAL; DOSE RESPONSE; DRUG EFFECT; METABOLISM; MUSCLE RELAXATION; PATHOPHYSIOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; VASCULAR SMOOTH MUSCLE;

ANIMALS; BRADYKININ; BRAIN ISCHEMIA; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MIDDLE CEREBRAL ARTERY; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, BRADYKININ B1; RECEPTOR, BRADYKININ B2; RECEPTORS, BRADYKININ; REPERFUSION INJURY; UP-REGULATION;

EID: 85048743326     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0198553     Document Type: Article

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