Improvement of oxygen supply by an artificial carrier in combination with normobaric oxygenation decreases the volume of tissue hypoxia and tissue damage from transient focal cerebral ischemia

Experimental Neurology

Volumn 237, Issue 1, 2012, Pages 18-25

  Seiffge, David J ^a,d   Lapina, Natalia E ^a   Tsagogiorgas, Charalambos ^a   Theisinger, Bastian ^b   Henning, Robert H ^c   Schilling, Lothar ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NOVALIQ GMBH   (Germany)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Artificial oxygen carrier; Focal brain ischemia; Normobaric hyperoxygenation; Rat; Tissue hypoxia

Indexed keywords

ALKANE DERIVATIVE; OXYGEN; PIMONIDAZOLE; SODIUM CHLORIDE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL DAMAGE; CONTROLLED STUDY; DISEASE SEVERITY; HYPOXEMIA; IMMUNOREACTIVITY; MALE; MEAN ARTERIAL PRESSURE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; NORMOBARIC OXYGENATION; OXYGEN SUPPLY; OXYGEN TENSION; OXYGEN TRANSPORT; OXYGENATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; TISSUE INJURY;

ANIMALS; BLOOD SUBSTITUTES; HYPERBARIC OXYGENATION; HYPOXIA, BRAIN; ISCHEMIC ATTACK, TRANSIENT; MALE; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; SINGLE-BLIND METHOD; TIME FACTORS;

EID: 84863649193     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.06.007     Document Type: Article

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