Expressional changes in cerebrovascular receptors after experimental transient forebrain ischemia

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Johansson, Sara ^a   Povlsen, Gro ^a   Edvinsson, Lars ^a,b  

^a GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN; ENDOTHELIN RECEPTOR; SEROTONIN; SEROTONIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY MUSCLE; ARTICLE; BRAIN ARTERY; BRAIN BLOOD FLOW; BRAIN FUNCTION; COGNITIVE DEFECT; DISEASE ASSOCIATION; DISEASE DURATION; FOREBRAIN; IMMUNOCHEMISTRY; MALE; MESENCEPHALON; MYOGRAPHY; NEUROLOGIC EXAMINATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; REPERFUSION; RHOMBENCEPHALON; TRANSIENT ISCHEMIC ATTACK; UPREGULATION; VASOCONSTRICTION; WESTERN BLOTTING;

ANIMALS; CAROTID ARTERIES; ENDOTHELIN-1; GENE EXPRESSION REGULATION; ISCHEMIC ATTACK, TRANSIENT; MALE; PROSENCEPHALON; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN B; RECEPTOR, SEROTONIN, 5-HT1B; SEROTONIN; VASOCONSTRICTION; VIPER VENOMS;

RATTUS NORVEGICUS;

EID: 84864400938     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041852     Document Type: Article

References (36)

1. Hossmann KA,((2008)) Cerebral ischemia: models, methods and outcomes. Neuropharmacology 55:: 257--270. S0028-3908(07)00391-7 [pii];10.1016/j.neuropharm.2007.12.004 [doi].
2. Schneider A, Bottiger BW, Popp E,((2009)) Cerebral resuscitation after cardiocirculatory arrest. Anesth Analg 108:: 971--979. 108/3/971 [pii];10.1213/ane.0b013e318193ca99 [doi].
3. Harukuni I, Bhardwaj A,((2006)) Mechanisms of brain injury after global cerebral ischemia. Neurol Clin 24:: 1--21. S0733-8619(05)00084-8 [pii];10.1016/j.ncl.2005.10.004 [doi].
4. Bass E,((1985)) Cardiopulmonary arrest. Pathophysiology and neurologic complications. Ann Intern Med 103:: 920--927.
5. Richmond TS,((1997)) Cerebral resuscitation after global brain ischemia: linking research to practice. AACN Clin Issues 8:: 171--181.
6. Nunn J, Hodges H,((1994)) Cognitive deficits induced by global cerebral ischaemia: relationship to brain damage and reversal by transplants. Behav Brain Res 65:: 1--31. 0166-4328(94)90069-8 [pii].
7. Puttgen HA, Pantle H, Geocadin RG,((2009)) Management of cardiac arrest patients to maximize neurologic outcome. Curr Opin Crit Care 15:: 118--124. 10.1097/MCC.0b013e328326077c [doi];00075198-200904000-00008 [pii].
8. Zacharia BE, Hickman ZL, Grobelny BT, DeRosa PA, Ducruet AF, et al.((2009)) Complement inhibition as a proposed neuroprotective strategy following cardiac arrest. Mediators Inflamm 2009:: 124384. 10.1155/2009/124384 [doi].
9. Popp E, Bottiger BW,((2006)) Cerebral resuscitation: state of the art, experimental approaches and clinical perspectives. Neurol Clin 24:: 73--87, vi. S0733-8619(05)00089-7 [pii];10.1016/j.ncl.2005.10.008 [doi].
10. Hansen-Schwartz J, Hoel NL, Zhou M, Xu CB, Svendgaard NA, et al.((2003)) Subarachnoid hemorrhage enhances endothelin receptor expression and function in rat cerebral arteries. Neurosurgery 52:: 1188--1194.
11. Hansen-Schwartz J, Hoel NL, Xu CB, Svendgaard NA, Edvinsson L,((2003)) Subarachnoid hemorrhage-induced upregulation of the 5-HT1B receptor in cerebral arteries in rats. J Neurosurg 99:: 115--120. [doi].
12. Henriksson M, Stenman E, Edvinsson L,((2003)) Intracellular pathways involved in upregulation of vascular endothelin type B receptors in cerebral arteries of the rat. Stroke 34:: 1479--1483. 10.1161/01.STR.0000072984.79136.79 [doi];01.STR.0000072984.79136.79 [pii].
13. Henriksson M, Stenman E, Vikman P, Edvinsson L,((2007)) MEK1/2 inhibition attenuates vascular ETA and ETB receptor alterations after cerebral ischaemia. Exp Brain Res 178:: 470--476. 10.1007/s00221-006-0753-7 [doi].
14. Henriksson M, Stenman E, Vikman P, Edvinsson L,((2007)) Protein kinase C inhibition attenuates vascular ETB receptor upregulation and decreases brain damage after cerebral ischemia in rat. BMC Neurosci 8:: 7. 1471-2202-8-7 [pii];10.1186/1471-2202-8-7 [doi].
15. Barone FC, Globus MY, Price WJ, White RF, Storer BL, et al.((1994)) Endothelin levels increase in rat focal and global ischemia. J Cereb Blood Flow Metab 14:: 337--342.
16. Nishizawa S, Laher I,((2005)) Signaling mechanisms in cerebral vasospasm. Trends Cardiovasc Med 15:: 24--34. S1050-1738(04)00183-5 [pii];10.1016/j.tcm.2004.12.002 [doi].
17. Smith ML, Bendek G, Dahlgren N, Rosen I, Wieloch T, et al.((1984)) Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model. Acta Neurol Scand 69:: 385--401.
18. McBean DE, Kelly PA,((1998)) Rodent models of global cerebral ischemia: a comparison of two-vessel occlusion and four-vessel occlusion. Gen Pharmacol 30:: 431--434. S030636239700284X [pii].
19. Paljarvi L,((1984)) Brain lactic acidosis and ischemic cell damage: a topographic study with high-resolution light microscopy of early recovery in a rat model of severe incomplete ischemia. Acta Neuropathol 64:: 89--98.
20. Eklof B, Siesjo BK,((1972)) The effect of bilateral carotid artery ligation upon the blood flow and the energy state of the rat brain. Acta Physiol Scand 86:: 155--165.
21. Smith ML, Kalimo H, Warner DS, Siesjo BK,((1988)) Morphological lesions in the brain preceding the development of postischemic seizures. Acta Neuropathol 76:: 253--264.
22. Larsen CC, Povlsen GK, Rasmussen MN, Edvinsson L,((2010)) Improvement in neurological outcome and abolition of cerebrovascular endothelin B and 5-hydroxytryptamine 1B receptor upregulation through mitogen-activated protein kinase kinase 1/2 inhibition after subarachnoid hemorrhage in rats. J Neurosurg. 10.3171/2010.6.JNS1018 [doi].
23. Meyer OA, Tilson HA, Byrd WC, Riley MT,((1979)) A method for the routine assessment of fore- and hindlimb grip strength of rats and mice. Neurobehav Toxicol 1:: 233--236.
24. Hoel NL, Hansen-Schwartz J, Edvinsson L,((2001)) Selective up-regulation of 5-HT(1B/1D) receptors during organ culture of cerebral arteries. Neuroreport 12:: 1605--1608.
25. Smith ML, Auer RN, Siesjo BK,((1984)) The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia. Acta Neuropathol 64:: 319--332.
26. Bendel O, Alkass K, Bueters T, von Euler M, von Euler G,((2005)) Reproducible loss of CA1 neurons following carotid artery occlusion combined with halothane-induced hypotension. Brain Res 1033:: 135--142. S0006-8993(04)01835-9 [pii];10.1016/j.brainres.2004.11.033 [doi].
27. Sugawara T, Fujimura M, Morita-Fujimura Y, Kawase M, Chan PH,((1999)) Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia. J Neurosci 19:: RC39.
28. Kagstrom E, Smith ML, Siesjo BK,((1983)) Recirculation in the rat brain following incomplete ischemia. J Cereb Blood Flow Metab 3:: 183--192.
29. Grogaard B, Gerdin B, Arfors KE,((1988)) Inability of flunarizine, lidoflazine or magnesium to counteract delayed hypoperfusion after forebrain ischaemia in the rat. Acta Neurochir (Wien) 95:: 136--142.
30. Stenman E, Malmsjo M, Uddman E, Gido G, Wieloch T, et al.((2002)) Cerebral ischemia upregulates vascular endothelin ET(B) receptors in rat. Stroke 33:: 2311--2316.
31. Ansar S, Vikman P, Nielsen M, Edvinsson L,((2007)) Cerebrovascular ETB, 5-HT1B, and AT1 receptor upregulation correlates with reduction in regional CBF after subarachnoid hemorrhage. Am J Physiol Heart Circ Physiol 293:: H3750--H3758. 00857.2007 [pii];10.1152/ajpheart.00857.2007 [doi].
32. Rasmussen MNP, Hornbak M, Edvinsson L,((2009)) Enhanced contractile response of vascular contractile receptors following distal focal permanent occlusion. J Cereb Blood Flow Metab 29:: 166--178.
33. O'Collins VE, Macleod MR, Donnan GA, Horky LL, van der Worp BH, et al.((2006)) 1,026 experimental treatments in acute stroke. Ann Neurol 59:: 467--477. 10.1002/ana.20741 [doi].
34. Beg SA, Hansen-Schwartz JA, Vikman PJ, Xu CB, Edvinsson LI,((2006)) ERK1/2 inhibition attenuates cerebral blood flow reduction and abolishes ET(B) and 5-HT(1B) receptor upregulation after subarachnoid hemorrhage in rat. J Cereb Blood Flow Metab 26:: 846--856. 9600236 [pii];10.1038/sj.jcbfm.9600236 [doi].
35. Kaundal RK, Deshpande TA, Gulati A, Sharma SS,((2012)) Targeting endothelin receptors for pharmacotherapy of ischemic stroke: current scenario and future perspectives. Drug Discov Today. S1359-6446(12)00079-7 [pii];10.1016/j.drudis.2012.02.017 [doi].
36. Macdonald RL, Higashida RT, Keller E, Mayer SA, Molyneux A, et al.((2012)) Randomized Trial of Clazosentan in Patients With Aneurysmal Subarachnoid Hemorrhage Undergoing Endovascular Coiling. Stroke. STROKEAHA.111.648980 [pii];10.1161/STROKEAHA.111.648980 [doi].