Candida albicans-induced epithelial damage mediates translocation through intestinal barriers

mBio

Volumn 9, Issue 3, 2018, Pages

  Allert, Stefanie ^a   Förster, Toni M ^a   Svensson, Carl Magnus ^a   Richardson, Jonathan P ^b   Pawlik, Tony ^a   Hebecker, Betty ^a,c   Rudolphi, Sven ^a   Juraschitz, Marc ^a   Schaller, Martin ^d   Blagojevic, Mariana ^b   Morschhäuser, Joachim ^e   Figge, Marc Thilo ^a,f   Jacobsen, Ilse D ^a,f   Naglik, Julian R ^b   Kasper, Lydia ^a   Mogavero, Selene ^a   Hube, Bernhard ^a,f  

^a HANS KNÖLL INSTITUTE   (Germany)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

^d UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^e UNIVERSITY OF WÜRZBURG   (Germany)

^f FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Candida albicans; Candidalysin; Host cell damage; Host cell invasion; Intestinal barrier; Necrosis; Translocation

Indexed keywords

CYTOCHALASIN D; LACTATE DEHYDROGENASE;

ACTIN POLYMERIZATION; ALGORITHM; ARTICLE; BIOINFORMATICS; C2BBE1 CELL LINE; CANDIDA ALBICANS; CELL DAMAGE; COMPUTER MODEL; CONTROLLED STUDY; CYTOTOXICITY; DELETION MUTANT; DISEASE PREDISPOSITION; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; FUNGAL GENE; FUNGUS HYPHAE; GENE DELETION; GENE IDENTIFICATION; GENE ONTOLOGY; GENE TRANSLOCATION; GENETIC BACKGROUND; HOST CELL; HUMAN; HUMAN CELL; INTESTINE CELL; INVASIVE CANDIDIASIS; NONHUMAN; OPEN READING FRAME; PHENOTYPE; TRANSEPITHELIAL RESISTANCE; APOPTOSIS; CANDIDIASIS; CYTOLOGY; GENETICS; HOST PATHOGEN INTERACTION; INTESTINE; INTESTINE MUCOSA; MICROBIOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

APOPTOSIS; CANDIDA ALBICANS; CANDIDIASIS; ENTEROCYTES; EPITHELIAL CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; INTESTINAL MUCOSA; INTESTINES;

EID: 85048284149     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00915-18     Document Type: Article

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