Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Xing, Junyue ^a   Ying, Yongquan ^b   Mao, Chenxi ^c   Liu, Yiwei ^a   Wang, Tingting ^a   Zhao, Qian ^a   Zhang, Xiaoling ^a   Yan, Fuxia ^a   Zhang, Hao ^a  

^a FUWAI HOSPITAL   (China)

^b TAIZHOU HOSPITAL OF ZHEJIANG PROVINCE   (China)

^c THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; ALKALINE PHOSPHATASE; BETA ACTIN; GALACTOSE; PROTEIN P21; PROTEIN P27; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

BONE; CARDIOVASCULAR DISEASE; CELL COMPONENT; DIGESTIVE SYSTEM; ENZYME; ENZYME ACTIVITY; HYPOXIA; INDUCED RESPONSE; MICROBIAL COMMUNITY; MICROORGANISM; SENESCENCE; SUGAR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BACTEROIDETES; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL AGING; CELL DIFFERENTIATION; CELL STRUCTURE; CHILD; CONTROLLED STUDY; CYANOTIC HEART DISEASE; ENTEROBACTERIACEAE; ENZYME ACTIVITY; FEMALE; FIRMICUTES; HUMAN; HUMAN CELL; HYPOXIA; INTESTINE FLORA; LACTOBACILLACEAE; LACTOBACILLUS; MAJOR CLINICAL STUDY; MALE; MICROBIAL COMMUNITY; MICROBIAL DIVERSITY; NEWBORN; NONHUMAN; OXYGEN SATURATION; OXYGEN TENSION; PHENOTYPE; PROTEOBACTERIA; RAT; RUMINOCOCCACEAE; ANIMAL; BONE MARROW CELL; CHRONIC DISEASE; CONGENITAL HEART MALFORMATION; CYANOSIS; DISEASE MODEL; INFANT; MESENCHYMAL STEM CELL; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; PRESCHOOL CHILD; SPRAGUE DAWLEY RAT;

LACTOBACILLUS; RATTUS;

ANIMALS; ANIMALS, NEWBORN; BONE MARROW CELLS; CELLULAR SENESCENCE; CHILD, PRESCHOOL; CHRONIC DISEASE; CYANOSIS; DISEASE MODELS, ANIMAL; FEMALE; GALACTOSE; GASTROINTESTINAL MICROBIOME; HEART DEFECTS, CONGENITAL; HUMANS; HYPOXIA; INFANT; LACTOBACILLUS; MALE; MESENCHYMAL STEM CELLS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 85047727641     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-04453-9     Document Type: Article

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