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Volumn 12, Issue 3, 2017, Pages

Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure

Author keywords

[No Author keywords available]

Indexed keywords

RNA 16S;

EID: 85016036470     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0174099     Document Type: Article
Times cited : (189)

References (47)
  • 1
    • 84897138296 scopus 로고    scopus 로고
    • Role of the microbiota in immunity and inflammation
    • PMID: 24679531
    • Belkaid Y, Hand TW. Role of the microbiota in immunity and inflammation. Cell. 2014; 157(1):121-41. https://doi.org/10.1016/j.cell.2014.03.011 PMID: 24679531
    • (2014) Cell , vol.157 , Issue.1 , pp. 121-141
    • Belkaid, Y.1    Hand, T.W.2
  • 2
    • 84960334772 scopus 로고    scopus 로고
    • Signaling in host-associated microbial communities
    • PMID: 26967294
    • Fischbach MA, Segre JA. Signaling in Host-Associated Microbial Communities. Cell. 2016; 164 (6):1288-300. https://doi.org/10.1016/j.cell.2016.02.037 PMID: 26967294
    • (2016) Cell , vol.164 , Issue.6 , pp. 1288-1300
    • Fischbach, M.A.1    Segre, J.A.2
  • 3
    • 84858439578 scopus 로고    scopus 로고
    • The human microbiome: At the interface of health and disease
    • PMID: 22411464
    • Cho I, Blaser MJ. The human microbiome: at the interface of health and disease. Nat Rev Genet. 2012; 13(4):260-70. https://doi.org/10.1038/nrg3182 PMID: 22411464
    • (2012) Nat Rev Genet. , vol.13 , Issue.4 , pp. 260-270
    • Cho, I.1    Blaser, M.J.2
  • 4
    • 84958841613 scopus 로고    scopus 로고
    • The gut microbiota and host health: A new clinical frontier
    • PMID: 26338727
    • Marchesi JR, Adams DH, Fava F, Hermes GD, Hirschfield GM, Hold G, et al. The gut microbiota and host health: a new clinical frontier. Gut. 2016; 65(2):330-9. https://doi.org/10.1136/gutjnl-2015-309990 PMID: 26338727
    • (2016) Gut. , vol.65 , Issue.2 , pp. 330-339
    • Marchesi, J.R.1    Adams, D.H.2    Fava, F.3    Hermes, G.D.4    Hirschfield, G.M.5    Hold, G.6
  • 5
    • 34948814651 scopus 로고    scopus 로고
    • Altered intestinal function in patients with chronic heart failure
    • PMID: 17936155
    • Sandek A, Bauditz J, Swidsinski A, Buhner S, Weber-Eibel J, von Haehling S, et al. Altered intestinal function in patients with chronic heart failure. J Am Coll Cardiol. 2007; 50(16):1561-9. https://doi.org/10.1016/j.jacc.2007.07.016 PMID: 17936155
    • (2007) J Am Coll Cardiol. , vol.50 , Issue.16 , pp. 1561-1569
    • Sandek, A.1    Bauditz, J.2    Swidsinski, A.3    Buhner, S.4    Weber-Eibel, J.5    Von Haehling, S.6
  • 6
    • 84919785324 scopus 로고    scopus 로고
    • Intestinal blood flow in patients with chronic heart failure: A link with bacterial growth, gastrointestinal symptoms, and cachexia
    • PMID: 25212642
    • Sandek A, Swidsinski A, Schroedl W, Watson A, Valentova M, Herrmann R, et al. Intestinal blood flow in patients with chronic heart failure: a link with bacterial growth, gastrointestinal symptoms, and cachexia. J Am Coll Cardiol. 2014; 64(11):1092-102. https://doi.org/10.1016/j.jacc.2014.06.1179 PMID: 25212642
    • (2014) J Am Coll Cardiol. , vol.64 , Issue.11 , pp. 1092-1102
    • Sandek, A.1    Swidsinski, A.2    Schroedl, W.3    Watson, A.4    Valentova, M.5    Herrmann, R.6
  • 7
    • 84881103162 scopus 로고    scopus 로고
    • Abdominal contributions to cardiorenal dysfunction in congestive heart failure
    • PMID: 23747781
    • Verbrugge FH, Dupont M, Steels P, Grieten L, Malbrain M, Tang WH, et al. Abdominal contributions to cardiorenal dysfunction in congestive heart failure. J Am Coll Cardiol. 2013; 62(6):485-95. https://doi.org/10.1016/j.jacc.2013.04.070 PMID: 23747781
    • (2013) J Am Coll Cardiol. , vol.62 , Issue.6 , pp. 485-495
    • Verbrugge, F.H.1    Dupont, M.2    Steels, P.3    Grieten, L.4    Malbrain, M.5    Tang, W.H.6
  • 8
    • 84894288139 scopus 로고    scopus 로고
    • The heart and the gut
    • PMID: 23864132
    • Rogler G, Rosano G. The heart and the gut. Eur Heart J. 2014; 35(7):426-30. https://doi.org/10.1093/eurheartj/eht271 PMID: 23864132
    • (2014) Eur Heart J. , vol.35 , Issue.7 , pp. 426-430
    • Rogler, G.1    Rosano, G.2
  • 9
    • 84960802334 scopus 로고    scopus 로고
    • Intersections between microbiome and heart failure: Revisiting the gut hypothesis
    • PMID: 26435097
    • Nagatomo Y, Tang WH. Intersections Between Microbiome and Heart Failure: Revisiting the Gut Hypothesis. J Card Fail. 2015; 21(12):973-80. https://doi.org/10.1016/j.cardfail.2015.09.017 PMID: 26435097
    • (2015) J Card Fail , vol.21 , Issue.12 , pp. 973-980
    • Nagatomo, Y.1    Tang, W.H.2
  • 10
    • 84964861235 scopus 로고    scopus 로고
    • Gastrointestinal and liver issues in heart failure
    • PMID: 27143152
    • Sundaram V, Fang JC. Gastrointestinal and Liver Issues in Heart Failure. Circulation. 2016; 133 (17):1696-703. https://doi.org/10.1161/CIRCULATIONAHA.115.020894 PMID: 27143152
    • (2016) Circulation , vol.133 , Issue.17 , pp. 1696-1703
    • Sundaram, V.1    Fang, J.C.2
  • 11
    • 84870024869 scopus 로고    scopus 로고
    • Cardiorenal syndrome: The emerging role of protein-bound uremic toxins
    • PMID: 23139286
    • Lekawanvijit S, Kompa AR, Wang BH, Kelly DJ, Krum H. Cardiorenal syndrome: the emerging role of protein-bound uremic toxins. Circ Res. 2012; 111(11):1470-83. https://doi.org/10.1161/CIRCRESAHA. 112.278457 PMID: 23139286
    • (2012) Circ Res. , vol.111 , Issue.11 , pp. 1470-1483
    • Lekawanvijit, S.1    Kompa, A.R.2    Wang, B.H.3    Kelly, D.J.4    Krum, H.5
  • 12
    • 84908377019 scopus 로고    scopus 로고
    • Prognostic value of elevated levels of intestinal microbe-generated metabolite trimethylamine-N-oxide in patients with heart failure: Refining the gut hypothesis
    • PMID: 25444145
    • Tang WH, Wang Z, Fan Y, Levison B, Hazen JE, Donahue LM, et al. Prognostic value of elevated levels of intestinal microbe-generated metabolite trimethylamine-N-oxide in patients with heart failure: refining the gut hypothesis. J Am Coll Cardiol. 2014; 64(18):1908-14. https://doi.org/10.1016/j.jacc.2014.02. 617 PMID: 25444145
    • (2014) J Am Coll Cardiol. , vol.64 , Issue.18 , pp. 1908-1914
    • Tang, W.H.1    Wang, Z.2    Fan, Y.3    Levison, B.4    Hazen, J.E.5    Donahue, L.M.6
  • 13
    • 84955278869 scopus 로고    scopus 로고
    • Choline diet and its gut microbe-derived metabolite, trimethylamine N-oxide, exacerbate pressure overload-induced heart failure
    • PMID: 26699388
    • Organ CL, Otsuka H, Bhushan S, Wang Z, Bradley J, Trivedi R, et al. Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure. Circ Heart Fail. 2016; 9(1):e002314. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002314 PMID: 26699388
    • (2016) Circ Heart Fail , vol.9 , Issue.1 , pp. e002314
    • Organ, C.L.1    Otsuka, H.2    Bhushan, S.3    Wang, Z.4    Bradley, J.5    Trivedi, R.6
  • 14
    • 84860909327 scopus 로고    scopus 로고
    • Intestinal microbiota determine severity of myocardial infarction in rats
    • Epub 2012/01/17. PMID: 22247331
    • Lam V, Su J, Koprowski S, Hsu A, Tweddell JS, Rafiee P, et al. Intestinal microbiota determine severity of myocardial infarction in rats. Faseb J. 2012; 26(4):1727-35. Epub 2012/01/17. https://doi.org/10.1096/fj.11-197921 PMID: 22247331
    • (2012) Faseb J. , vol.26 , Issue.4 , pp. 1727-1735
    • Lam, V.1    Su, J.2    Koprowski, S.3    Hsu, A.4    Tweddell, J.S.5    Rafiee, P.6
  • 15
    • 84902794566 scopus 로고    scopus 로고
    • Probiotic administration attenuates myocardial hypertrophy and heart failure after myocardial infarction in the rat
    • PMID: 24625365
    • Gan XT, Ettinger G, Huang CX, Burton JP, Haist JV, Rajapurohitam V, et al. Probiotic administration attenuates myocardial hypertrophy and heart failure after myocardial infarction in the rat. Circ Heart Fail. 2014; 7(3):491-9. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000978 PMID: 24625365
    • (2014) Circ Heart Fail , vol.7 , Issue.3 , pp. 491-499
    • Gan, X.T.1    Ettinger, G.2    Huang, C.X.3    Burton, J.P.4    Haist, J.V.5    Rajapurohitam, V.6
  • 16
    • 38949166977 scopus 로고    scopus 로고
    • An improved DNA isolation method for metagenomic analysis of the microbial flora of the human intestine
    • Morita H, Kuwahara T, Oshima K, Sasamoto H, Itoh K, Hattori M, et al. An improved DNA isolation method for metagenomic analysis of the microbial flora of the human intestine. Microbes Environ. 2007; 22(3):214-22.
    • (2007) Microbes Environ. , vol.22 , Issue.3 , pp. 214-222
    • Morita, H.1    Kuwahara, T.2    Oshima, K.3    Sasamoto, H.4    Itoh, K.5    Hattori, M.6
  • 17
    • 84881478467 scopus 로고    scopus 로고
    • Robustness of gut microbiota of healthy adults in response to probiotic intervention revealed by high-throughput pyrosequencing
    • PMID: 23571675
    • Kim SW, Suda W, Kim S, Oshima K, Fukuda S, Ohno H, et al. Robustness of gut microbiota of healthy adults in response to probiotic intervention revealed by high-throughput pyrosequencing. DNA Res. 2013; 20(3):241-53. https://doi.org/10.1093/dnares/dst006 PMID: 23571675
    • (2013) DNA Res. , vol.20 , Issue.3 , pp. 241-253
    • Kim, S.W.1    Suda, W.2    Kim, S.3    Oshima, K.4    Fukuda, S.5    Ohno, H.6
  • 18
    • 78751575501 scopus 로고    scopus 로고
    • UniFrac: An effective distance metric for microbial community comparison
    • PMID: 20827291
    • Lozupone C, Lladser ME, Knights D, Stombaugh J, Knight R. UniFrac: an effective distance metric for microbial community comparison. ISME J. 2011; 5(2):169-72. https://doi.org/10.1038/ismej.2010.133 PMID: 20827291
    • (2011) ISME J. , vol.5 , Issue.2 , pp. 169-172
    • Lozupone, C.1    Lladser, M.E.2    Knights, D.3    Stombaugh, J.4    Knight, R.5
  • 19
    • 33947269742 scopus 로고    scopus 로고
    • Quantitative and qualitative beta diversity measures lead to different insights into factors that structure microbial communities
    • PMID: 17220268
    • Lozupone CA, Hamady M, Kelley ST, Knight R. Quantitative and qualitative beta diversity measures lead to different insights into factors that structure microbial communities. Appl Environ Microbiol. 2007; 73(5):1576-85. https://doi.org/10.1128/AEM.01996-06 PMID: 17220268
    • (2007) Appl Environ Microbiol. , vol.73 , Issue.5 , pp. 1576-1585
    • Lozupone, C.A.1    Hamady, M.2    Kelley, S.T.3    Knight, R.4
  • 20
    • 84879472039 scopus 로고    scopus 로고
    • Heart failure in elderly patients: Distinctive features and unresolved issues
    • PMID: 23429975
    • Lazzarini V, Mentz RJ, Fiuzat M, Metra M, O'Connor CM. Heart failure in elderly patients: distinctive features and unresolved issues. Eur J Heart Fail. 2013; 15(7):717-23. https://doi.org/10.1093/eurjhf/hft028 PMID: 23429975
    • (2013) Eur J Heart Fail , vol.15 , Issue.7 , pp. 717-723
    • Lazzarini, V.1    Mentz, R.J.2    Fiuzat, M.3    Metra, M.4    O'Connor, C.M.5
  • 21
    • 84921304368 scopus 로고    scopus 로고
    • Antimicrobial defense of the intestine
    • PMID: 25607457
    • Mukherjee S, Hooper LV. Antimicrobial defense of the intestine. Immunity. 2015; 42(1):28-39. https://doi.org/10.1016/j.immuni.2014.12.028 PMID: 25607457
    • (2015) Immunity , vol.42 , Issue.1 , pp. 28-39
    • Mukherjee, S.1    Hooper, L.V.2
  • 22
    • 84959082239 scopus 로고    scopus 로고
    • Pathogenic gut flora in patients with chronic heart failure
    • PMID: 26682791
    • Pasini E, Aquilani R, Testa C, Baiardi P, Angioletti S, Boschi F, et al. Pathogenic Gut Flora in Patients With Chronic Heart Failure. JACC Heart Fail. 2016; 4(3):220-7. https://doi.org/10.1016/j.jchf.2015.10.009 PMID: 26682791
    • (2016) JACC Heart Fail , vol.4 , Issue.3 , pp. 220-227
    • Pasini, E.1    Aquilani, R.2    Testa, C.3    Baiardi, P.4    Angioletti, S.5    Boschi, F.6
  • 23
    • 84929857413 scopus 로고    scopus 로고
    • Recent advances in characterizing the gastrointestinal microbiome in Crohn's disease: A systematic review
    • PMID: 25844959
    • Wright EK, Kamm MA, Teo SM, Inouye M, Wagner J, Kirkwood CD. Recent advances in characterizing the gastrointestinal microbiome in Crohn's disease: a systematic review. Inflamm Bowel Dis. 2015; 21 (6):1219-28. https://doi.org/10.1097/MIB.0000000000000382 PMID: 25844959
    • (2015) Inflamm Bowel Dis. , vol.21 , Issue.6 , pp. 1219-1228
    • Wright, E.K.1    Kamm, M.A.2    Teo, S.M.3    Inouye, M.4    Wagner, J.5    Kirkwood, C.D.6
  • 24
    • 84891524250 scopus 로고    scopus 로고
    • Assessing the human gut microbiota in metabolic diseases
    • PMID: 24065795
    • Karlsson F, Tremaroli V, Nielsen J, Backhed F. Assessing the human gut microbiota in metabolic diseases. Diabetes. 2013; 62(10):3341-9. https://doi.org/10.2337/db13-0844 PMID: 24065795
    • (2013) Diabetes , vol.62 , Issue.10 , pp. 3341-3349
    • Karlsson, F.1    Tremaroli, V.2    Nielsen, J.3    Backhed, F.4
  • 25
    • 84937549863 scopus 로고    scopus 로고
    • Gut dysbiosis is linked to hypertension
    • PMID: 25870193
    • Yang T, Santisteban MM, Rodriguez V, Li E, Ahmari N, Carvajal JM, et al. Gut dysbiosis is linked to hypertension. Hypertension. 2015; 65(6):1331-40. https://doi.org/10.1161/HYPERTENSIONAHA.115. 05315 PMID: 25870193
    • (2015) Hypertension. , vol.65 , Issue.6 , pp. 1331-1340
    • Yang, T.1    Santisteban, M.M.2    Rodriguez, V.3    Li, E.4    Ahmari, N.5    Carvajal, J.M.6
  • 26
    • 84988372530 scopus 로고    scopus 로고
    • The gut microbiota and metabolic disease: Current understanding and future perspectives
    • PMID: 27071815
    • Arora T, Backhed F. The gut microbiota and metabolic disease: current understanding and future perspectives. J Intern Med. 2016; 280(4):339-49. https://doi.org/10.1111/joim.12508 PMID: 27071815
    • (2016) J Intern Med. , vol.280 , Issue.4 , pp. 339-349
    • Arora, T.1    Backhed, F.2
  • 27
    • 84963838320 scopus 로고    scopus 로고
    • Brain-gut-bone marrow axis: Implications for hypertension and related therapeutics
    • PMID: 27081113
    • Santisteban MM, Kim S, Pepine CJ, Raizada MK. Brain-Gut-Bone Marrow Axis: Implications for Hypertension and Related Therapeutics. Circ Res. 2016; 118(8):1327-36. https://doi.org/10.1161/CIRCRESAHA.116.307709 PMID: 27081113
    • (2016) Circ Res. , vol.118 , Issue.8 , pp. 1327-1336
    • Santisteban, M.M.1    Kim, S.2    Pepine, C.J.3    Raizada, M.K.4
  • 28
    • 0028126829 scopus 로고
    • The phylogeny of the genus clostridium: Proposal of five new genera and eleven new species combinations
    • PMID: 7981107
    • Collins MD, Lawson PA, Willems A, Cordoba JJ, Fernandez-Garayzabal J, Garcia P, et al. The phylogeny of the genus Clostridium: proposal of five new genera and eleven new species combinations. Int J Syst Bacteriol. 1994; 44(4):812-26. https://doi.org/10.1099/00207713-44-4-812 PMID: 7981107
    • (1994) Int J Syst Bacteriol. , vol.44 , Issue.4 , pp. 812-826
    • Collins, M.D.1    Lawson, P.A.2    Willems, A.3    Cordoba, J.J.4    Fernandez-Garayzabal, J.5    Garcia, P.6
  • 29
    • 0036199905 scopus 로고    scopus 로고
    • Reclassification of eubacterium formicigenerans holdeman and moore 1974 as dorea formicigenerans gen. Nov., comb. Nov., and description of dorea longicatena sp. Nov., isolated from human faeces
    • PMID: 11931151
    • Taras D, Simmering R, Collins MD, Lawson PA, Blaut M. Reclassification of Eubacterium formicigenerans Holdeman and Moore 1974 as Dorea formicigenerans gen. nov., comb. nov., and description of Dorea longicatena sp. nov., isolated from human faeces. Int J Syst Evol Microbiol. 2002; 52(Pt 2):423-8. https://doi.org/10.1099/00207713-52-2-423 PMID: 11931151
    • (2002) Int J Syst Evol Microbiol. , vol.52 , pp. 423-428
    • Taras, D.1    Simmering, R.2    Collins, M.D.3    Lawson, P.A.4    Blaut, M.5
  • 30
    • 63849241608 scopus 로고    scopus 로고
    • Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine
    • PMID: 19222573
    • Louis P, Flint HJ. Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine. FEMS Microbiol Lett. 2009; 294(1):1-8. https://doi.org/10.1111/j.1574-6968. 2009.01514.x PMID: 19222573
    • (2009) FEMS Microbiol Lett. , vol.294 , Issue.1 , pp. 1-8
    • Louis, P.1    Flint, H.J.2
  • 31
    • 84865525269 scopus 로고    scopus 로고
    • Butyrate: Implications for intestinal function
    • PMID: 22797568
    • Leonel AJ, Alvarez-Leite JI. Butyrate: implications for intestinal function. Curr Opin Clin Nutr Metab Care. 2012; 15(5):474-9. https://doi.org/10.1097/MCO.0b013e32835665fa PMID: 22797568
    • (2012) Curr Opin Clin Nutr Metab Care , vol.15 , Issue.5 , pp. 474-479
    • Leonel, A.J.1    Alvarez-Leite, J.I.2
  • 32
    • 84890564250 scopus 로고    scopus 로고
    • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
    • Epub 2013/11/15. PMID: 24226770
    • Furusawa Y, Obata Y, Fukuda S, Endo TA, Nakato G, Takahashi D, et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature. 2013; 504(7480):446-50. Epub 2013/11/15. https://doi.org/10.1038/nature12721 PMID: 24226770
    • (2013) Nature , vol.504 , Issue.7480 , pp. 446-450
    • Furusawa, Y.1    Obata, Y.2    Fukuda, S.3    Endo, T.A.4    Nakato, G.5    Takahashi, D.6
  • 33
    • 84910139873 scopus 로고    scopus 로고
    • Collateral damage: Microbiota-derived metabolites and immune function in the antibiotic era
    • PMID: 25121745
    • Lopez CA, Kingsbury DD, Velazquez EM, Baumler AJ. Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era. Cell Host Microbe. 2014; 16(2):156-63. https://doi.org/10.1016/j.chom.2014.07.009 PMID: 25121745
    • (2014) Cell Host Microbe. , vol.16 , Issue.2 , pp. 156-163
    • Lopez, C.A.1    Kingsbury, D.D.2    Velazquez, E.M.3    Baumler, A.J.4
  • 34
    • 3142628485 scopus 로고    scopus 로고
    • Contribution of acetate to butyrate formation by human faecal bacteria
    • PMID: 15182395
    • Duncan SH, Holtrop G, Lobley GE, Calder AG, Stewart CS, Flint HJ. Contribution of acetate to butyrate formation by human faecal bacteria. Br J Nutr. 2004; 91(6):915-23. https://doi.org/10.1079/BJN20041150 PMID: 15182395
    • (2004) Br J Nutr. , vol.91 , Issue.6 , pp. 915-923
    • Duncan, S.H.1    Holtrop, G.2    Lobley, G.E.3    Calder, A.G.4    Stewart, C.S.5    Flint, H.J.6
  • 35
    • 84973667684 scopus 로고    scopus 로고
    • Acetate mediates a microbiomebrain-beta-cell axis to promote metabolic syndrome
    • PMID: 27279214
    • Perry RJ, Peng L, Barry NA, Cline GW, Zhang D, Cardone RL, et al. Acetate mediates a microbiomebrain-beta-cell axis to promote metabolic syndrome. Nature. 2016; 534(7606):213-7. https://doi.org/10.1038/nature18309 PMID: 27279214
    • (2016) Nature , vol.534 , Issue.7606 , pp. 213-217
    • Perry, R.J.1    Peng, L.2    Barry, N.A.3    Cline, G.W.4    Zhang, D.5    Cardone, R.L.6
  • 36
    • 84910125156 scopus 로고    scopus 로고
    • Determining microbial products and identifying molecular targets in the human microbiome
    • PMID: 25440055
    • Joice R, Yasuda K, Shafquat A, Morgan XC, Huttenhower C. Determining microbial products and identifying molecular targets in the human microbiome. Cell Metab. 2014; 20(5):731-41. https://doi.org/10.1016/j.cmet.2014.10.003 PMID: 25440055
    • (2014) Cell Metab. , vol.20 , Issue.5 , pp. 731-741
    • Joice, R.1    Yasuda, K.2    Shafquat, A.3    Morgan, X.C.4    Huttenhower, C.5
  • 37
    • 84930004775 scopus 로고    scopus 로고
    • Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide
    • PMID: 25784704
    • Romano KA, Vivas EI, Amador-Noguez D, Rey FE. Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide. MBio. 2015; 6(2):e02481. https://doi.org/10.1128/mBio.02481-14 PMID: 25784704
    • (2015) MBio. , vol.6 , Issue.2 , pp. e02481
    • Romano, K.A.1    Vivas, E.I.2    Amador-Noguez, D.3    Rey, F.E.4
  • 38
    • 84950297830 scopus 로고    scopus 로고
    • Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis
    • PMID: 26687352
    • Wang Z, Roberts AB, Buffa JA, Levison BS, Zhu W, Org E, et al. Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis. Cell. 2015; 163(7):1585-95. https://doi.org/10.1016/j.cell.2015.11.055 PMID: 26687352
    • (2015) Cell , vol.163 , Issue.7 , pp. 1585-1595
    • Wang, Z.1    Roberts, A.B.2    Buffa, J.A.3    Levison, B.S.4    Zhu, W.5    Org, E.6
  • 39
    • 84968918909 scopus 로고    scopus 로고
    • Population-level analysis of gut microbiome variation
    • PMID: 27126039
    • Falony G, Joossens M, Vieira-Silva S, Wang J, Darzi Y, Faust K, et al. Population-level analysis of gut microbiome variation. Science. 2016; 352(6285):560-4. https://doi.org/10.1126/science.aad3503 PMID: 27126039
    • (2016) Science , vol.352 , Issue.6285 , pp. 560-564
    • Falony, G.1    Joossens, M.2    Vieira-Silva, S.3    Wang, J.4    Darzi, Y.5    Faust, K.6
  • 40
    • 84968901892 scopus 로고    scopus 로고
    • Populationbased metagenomics analysis reveals markers for gut microbiome composition and diversity
    • PMID: 27126040
    • Zhernakova A, Kurilshikov A, Bonder MJ, Tigchelaar EF, Schirmer M, Vatanen T, et al. Populationbased metagenomics analysis reveals markers for gut microbiome composition and diversity. Science. 2016; 352(6285):565-9. https://doi.org/10.1126/science.aad3369 PMID: 27126040
    • (2016) Science , vol.352 , Issue.6285 , pp. 565-569
    • Zhernakova, A.1    Kurilshikov, A.2    Bonder, M.J.3    Tigchelaar, E.F.4    Schirmer, M.5    Vatanen, T.6
  • 41
    • 84954286591 scopus 로고    scopus 로고
    • Proton pump inhibitors affect the gut microbiome
    • PMID: 26657899
    • Imhann F, Bonder MJ, Vich Vila A, Fu J, Mujagic Z, Vork L, et al. Proton pump inhibitors affect the gut microbiome. Gut. 2016; 65(5):740-8. https://doi.org/10.1136/gutjnl-2015-310376 PMID: 26657899
    • (2016) Gut. , vol.65 , Issue.5 , pp. 740-748
    • Imhann, F.1    Bonder, M.J.2    Vich Vila, A.3    Fu, J.4    Mujagic, Z.5    Vork, L.6
  • 42
    • 84954286470 scopus 로고    scopus 로고
    • Proton pump inhibitors alter the composition of the gut microbiota
    • PMID: 26719299
    • Jackson MA, Goodrich JK, Maxan ME, Freedberg DE, Abrams JA, Poole AC, et al. Proton pump inhibitors alter the composition of the gut microbiota. Gut. 2016; 65(5):749-56. https://doi.org/10.1136/gutjnl-2015-310861 PMID: 26719299
    • (2016) Gut. , vol.65 , Issue.5 , pp. 749-756
    • Jackson, M.A.1    Goodrich, J.K.2    Maxan, M.E.3    Freedberg, D.E.4    Abrams, J.A.5    Poole, A.C.6
  • 44
    • 84864722033 scopus 로고    scopus 로고
    • Gut microbiota composition correlates with diet and health in the elderly
    • PMID: 22797518
    • Claesson MJ, Jeffery IB, Conde S, Power SE, O'Connor EM, Cusack S, et al. Gut microbiota composition correlates with diet and health in the elderly. Nature. 2012; 488(7410):178-84. https://doi.org/10.1038/nature11319 PMID: 22797518
    • (2012) Nature , vol.488 , Issue.7410 , pp. 178-184
    • Claesson, M.J.1    Jeffery, I.B.2    Conde, S.3    Power, S.E.4    O'Connor, E.M.5    Cusack, S.6
  • 45
    • 84902996282 scopus 로고    scopus 로고
    • Heart failure with preserved ejection fraction: Molecular pathways of the aging myocardium
    • PMID: 24951760
    • Loffredo FS, Nikolova AP, Pancoast JR, Lee RT. Heart failure with preserved ejection fraction: molecular pathways of the aging myocardium. Circ Res. 2014; 115(1):97-107. https://doi.org/10.1161/CIRCRESAHA.115.302929 PMID: 24951760
    • (2014) Circ Res. , vol.115 , Issue.1 , pp. 97-107
    • Loffredo, F.S.1    Nikolova, A.P.2    Pancoast, J.R.3    Lee, R.T.4
  • 46
    • 84948992933 scopus 로고    scopus 로고
    • Gut microbiota and aging
    • PMID: 26785481
    • O'Toole PW, Jeffery IB. Gut microbiota and aging. Science. 2015; 350(6265):1214-5. https://doi.org/10.1126/science.aac8469 PMID: 26785481
    • (2015) Science , vol.350 , Issue.6265 , pp. 1214-1215
    • O'Toole, P.W.1    Jeffery, I.B.2
  • 47
    • 84959523025 scopus 로고    scopus 로고
    • Taking it personally: Personalized utilization of the human microbiome in health and disease
    • PMID: 26764593
    • Zmora N, Zeevi D, Korem T, Segal E, Elinav E. Taking it Personally: Personalized Utilization of the Human Microbiome in Health and Disease. Cell Host Microbe. 2016; 19(1):12-20. https://doi.org/10.1016/j.chom.2015.12.016 PMID: 26764593
    • (2016) Cell Host Microbe. , vol.19 , Issue.1 , pp. 12-20
    • Zmora, N.1    Zeevi, D.2    Korem, T.3    Segal, E.4    Elinav, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.