Transcriptional and functional analysis of galactooligosaccharide uptake by lacS in Lactobacillus acidophilus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 43, 2011, Pages 17785-17790

  Andersen, Joakim M ^a,d   Barrangou, Rodolphe ^b   Hachem, Maher Abou ^a   Lahtinen, Sampo ^c   Goh, Yong Jun ^d   Svensson, Birte ^a   Klaenhammer, Todd R ^d  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b Danisco USA Inc   (United States)

^c Health and Nutrition   (Finland)

^d NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Catabolite repression element; Lactose permease

Indexed keywords

BACTERIAL ENZYME; BETA GALACTOSIDASE; BETA GALACTOSIDASE LACA; BETA GALACTOSIDASE LACLM; GALACTOSE OLIGOSACCHARIDE; GALACTOSIDE; GLUCOSE; LACS PERMEASE; LACTITOL; LACTOSE; OLIGONUCLEOTIDE; PENTOSE; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIUM MUTANT; CARBOHYDRATE TRANSPORT; CATABOLISM; DNA MICROARRAY; GENE CLUSTER; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; GENE LOCUS; GENETIC TRANSCRIPTION; GENOME; GLUCOSE UTILIZATION; LACTOBACILLUS ACIDOPHILUS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; UPREGULATION;

BETA-GALACTOSIDASE; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION, BACTERIAL; LACTOBACILLUS ACIDOPHILUS; MEMBRANE TRANSPORT PROTEINS; MICROARRAY ANALYSIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGOSACCHARIDES; PREBIOTICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS ACIDOPHILUS NCFM;

EID: 80055067370     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114152108     Document Type: Article

References (54)

1. Tang ML, Lahtinen SJ, Boyle RJ (2010) Probiotics and prebiotics: Clinical effects in allergic disease. Curr Opin Pediatr 22:626-634.
2. Leyer GJ, Li S, Mubasher ME, Reifer C, Ouwehand AC (2009) Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics 124:e172-e179.
3. Hedin C, Whelan K, Lindsay JO (2007) Evidence for the use of probiotics and prebiotics in inflammatory bowel disease: A review of clinical trials. Proc Nutr Soc 66:307-315. (Pubitemid 47076227)
4. Reid G, et al. (2003) New scientific paradigms for probiotics and prebiotics. J Clin Gastroenterol 37:105-118. (Pubitemid 36875569)
5. Qin J, et al.; MetaHIT Consortium (2010) A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464(7285):59-65.
6. Roberfroid M (2007) Prebiotics: The concept revisited. J Nutr 137 (3, Suppl 2):830S-837S.
7. Callaway TR, et al. (2008) Probiotics, prebiotics and competitive exclusion for prophylaxis against bacterial disease. Anim Health Res Rev 9:217-225.
8. Park AR, Oh DK (2010) Galacto-oligosaccharide production using microbial beta-galactosidase: current state and perspectives. Appl Microbiol Biotechnol 85:1279-1286.
9. Macfarlane GT, Steed H, Macfarlane S (2008) Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics. J Appl Microbiol 104:305-344.
10. Rastall RA (2010) Functional oligosaccharides: Application and manufacture. Annu Rev Food Sci Technol 1:305-339.
11. Ben XM, et al. (2004) Supplementation of milk formula with galacto-oligosaccharides improves intestinal micro-flora and fermentation in term infants. Chin Med J (Engl) 117:927-931.
12. Silk DB, Davis A, Vulevic J, Tzortzis G, Gibson GR (2009) Clinical trial: The effects of a trans-galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome. Aliment Pharmacol Ther 29:508-518.
13. Drakoularakou A, Tzortzis G, Rastall RA, Gibson GR (2010) A double-blind, placebo-controlled, randomized human study assessing the capacity of a novel galacto-oligosaccharide mixture in reducing travellers' diarrhoea. Eur J Clin Nutr 64(2):146-152.
14. Sinclair HR, de Slegte J, Gibson GR, Rastall RA (2009) Galactooligosaccharides (GOS) inhibit Vibrio cholerae toxin binding to its GM1 receptor. J Agric Food Chem 57:3113-3119.
15. Quintero M, et al. (2011) Adherence inhibition of Cronobacter sakazakii to intestinal epithelial cells by prebiotic oligosaccharides. Curr Microbiol 62:1448-1454.
16. Searle LE, et al. (2010) Purified galactooligosaccharide, derived from a mixture produced by the enzymic activity of Bifidobacterium bifidum, reduces Salmonella enterica serovar Typhimurium adhesion and invasion in vitro and in vivo. J Med Microbiol 59:1428-1439.
17. Jones L, Seymour GB, Knox JP (1997) Localization of pectic galactan in tomato cell walls using a monoclonal antibody specific to (1[->]4)-[beta]-D- galactan. Plant Physiol 113:1405-1412. (Pubitemid 27210636)
18. Chaturvedi P, Warren CD, Ruiz-Palacios GM, Pickering LK, Newburg DS (1997) Milk oligosaccharide profiles by reversed-phase HPLC of their perbenzoylated derivatives. Anal Biochem 251(1):89-97. (Pubitemid 27352148)
19. Miller JB, McVeagh P (1999) Human milk oligosaccharides: 130 reasons to breast-feed. Br J Nutr 82:333-335.
20. Ninonuevo MR, et al. (2006) A strategy for annotating the human milk glycome. J Agric Food Chem 54:7471-7480. (Pubitemid 44645760)
21. Marcobal A, et al. (2010) Consumption of human milk oligosaccharides by gut-related microbes. J Agric Food Chem 58:5334-5340.
22. Sela DA, et al. (2008) The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome. Proc Natl Acad Sci USA 105:18964-18969.
23. Altermann E, et al. (2005) Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM. Proc Natl Acad Sci USA 102:3906-3912. (Pubitemid 40388530)
24. Duong T, Barrangou R, Russell WM, Klaenhammer TR (2006) Characterization of the tre locus and analysis of trehalose cryoprotection in Lactobacillus acidophilus NCFM. Appl Environ Microbiol 72:1218-1225. (Pubitemid 43271229)
25. Barrangou R, Altermann E, Hutkins R, Cano R, Klaenhammer TR (2003) Functional and comparative genomic analyses of an operon involved in fructooligosaccharide utilization by Lactobacillus acidophilus. Proc Natl Acad Sci USA 100:8957-8962. (Pubitemid 36899205)
26. Barrangou R, et al. (2006) Global analysis of carbohydrate utilization by Lactobacillus acidophilus using cDNA microarrays. Proc Natl Acad Sci USA 103:3816-3821. (Pubitemid 43376638)
27. Makarova K, et al. (2006) Comparative genomics of the lactic acid bacteria. Proc Natl Acad Sci USA 103:15611-15616. (Pubitemid 44625640)
28. Cantarel BL, et al. (2009) The Carbohydrate-Active EnZymes database (CAZy): An expert resource for Glycogenomics. Nucleic Acids Res 37(Database issue):D233-D238.
29. Bendtsen JD, Nielsen H, von Heijne G, Brunak S (2004) Improved prediction of signal peptides: SignalP 3.0. J Mol Biol 340:783-795. (Pubitemid 38829638)
30. Nguyen TH, et al. (2007) Characterization and molecular cloning of a heterodimeric beta-galactosidase from the probiotic strain Lactobacillus acidophilus R22. FEMS Microbiol Lett 269(1):136-144.
31. Pan Q, et al. (2010) Functional identification of a putative beta-galactosidase gene in the special lac gene cluster of Lactobacillus acidophilus. Curr Microbiol 60(1):172-178.
32. Fortina MG, Ricci G, Mora D, Guglielmetti S, Manachini PL (2003) Unusual organization for lactose and galactose gene clusters in Lactobacillus helveticus. Appl Environ Microbiol 69:3238-3243. (Pubitemid 36693327)
33. Goh YJ, et al. (2009) Development and application of a upp-based counterselective gene replacement system for the study of the S-layer protein SlpX of Lactobacillus acidophilus NCFM. Appl Environ Microbiol 75:3093-3105.
34. Ouwehand AC, Tiihonen K, Saarinen M, Putaala H, Rautonen N (2009) Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: Intestinal and immune parameters. Br J Nutr 101:367-375.
35. Leong-Morgenthaler P, Zwahlen MC, Hottinger H (1991) Lactose metabolism in Lactobacillus bulgaricus: Analysis of the primary structure and expression of the genes involved. J Bacteriol 173:1951-1957.
36. Vaughan EE, David S, de Vos WM (1996) The lactose transporter in Leuconostoc lactis is a new member of the LacS subfamily of galactoside-pentose- hexuronide translocators. Appl Environ Microbiol 62:1574-1582. (Pubitemid 26143426)
37. Vaillancourt K, Moineau S, Frenette M, Lessard C, Vadeboncoeur C (2002) Galactose and lactose genes from the galactose-positive bacterium Streptococcus salivarius and the phylogenetically related galactose-negative bacterium Streptococcus thermophilus: Organization, sequence, transcription, and activity of the gal gene products. J Bacteriol 184:785-793. (Pubitemid 34150226)
38. Ventura M, et al. (2009) Genome-scale analyses of health-promoting bacteria: Probiogenomics. Nat Rev Microbiol 7(1):61-71.
39. van de Guchte M, et al. (2006) The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution. Proc Natl Acad Sci USA 103:9274-9279.
40. Nelson KE, et al.; Human Microbiome Jumpstart Reference Strains Consortium (2010) A catalog of reference genomes from the human microbiome. Science 328:994-999.
41. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ (1990) Basic local alignment search tool. J Mol Biol 215:403-410.
42. Moro G, et al. (2002) Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formula-fed term infants. J Pediatr Gastroenterol Nutr 34:291-295. (Pubitemid 34437523)
43. Vulevic J, Drakoularakou A, Yaqoob P, Tzortzis G, Gibson GR (2008) Modulation of the fecal microflora profile and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers. Am J Clin Nutr 88:1438-1446.
44. Davis LM, Martínez I, Walter J, Hutkins R (2010) A dose dependent impact of prebiotic galactooligosaccharides on the intestinal microbiota of healthy adults. Int J Food Microbiol 144:285-292.
45. Ben XM, et al. (2008) Low level of galacto-oligosaccharide in infant formula stimulates growth of intestinal Bifidobacteria and Lactobacilli. World J Gastroenterol 14:6564-6568.
46. Pfeiler EA, Azcarate-Peril MA, Klaenhammer TR (2007) Characterization of a novel bile-inducible operon encoding a two-component regulatory system in Lactobacillus acidophilus. J Bacteriol 189:4624-4634. (Pubitemid 47025574)
47. Saier MH, Jr., Yen MR, Noto K, Tamang DG, Elkan C (2009) The transporter classification database: Recent advances. Nucleic Acids Res 37(Database issue):D274-D278.
48. Callanan M, et al. (2008) Genome sequence of Lactobacillus helveticus, an organism distinguished by selective gene loss and insertion sequence element expansion. J Bacteriol 190:727-735. (Pubitemid 351360089)
49. Kimmel SA, Roberts RF (1998) Development of a growth medium suitable for exopolysaccharide production by Lactobacillus delbrueckii ssp. bulgaricus RR. Int J Food Microbiol 40(1-2):87-92. (Pubitemid 28185197)
50. Daniels L, Zeikus JG (1975) Improved culture flask for obligate anaerobes. Appl Microbiol 29:710-711.
51. Walker DC, Klaenhammer TR (1994) Isolation of a novel IS3 group insertion element and construction of an integration vector for Lactobacillus spp. J Bacteriol 176:5330-5340. (Pubitemid 24273520)
52. Kingsford CL, Ayanbule K, Salzberg SL (2007) Rapid, accurate, computational discovery of Rho-independent transcription terminators illuminates their relationship to DNA uptake. Genome Biol 8(2):R22.
53. Law J, et al. (1995) A system to generate chromosomal mutations in Lactococcus lactis which allows fast analysis of targeted genes. J Bacteriol 177:7011-7018.
54. Russell WM, Klaenhammer TR (2001) Efficient system for directed integration into the Lactobacillus acidophilus and Lactobacillus gasseri chromosomes via homologous recombination. Appl Environ Microbiol 67:4361-4364. (Pubitemid 33641741)