Genetic factors as predictors of weight gain in young adult Dutch men and women

International Journal of Obesity

Volumn 26, Issue 4, 2002, Pages 517-528

  van Rossum, Caroline T M ^a   Hoebee, B ^a   Seidell, J C ^a   Bouchard, C ^b   van Baak, M A ^c   de Graaf, C P G M ^d   Chagnon, M ^b   de Graaf, C ^d   Saris, W H M ^c  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Adrenergic receptor; Candidate genes; Epidemiology; Genetics; Leptin receptor; Obesity; Peroxisome proliferator activated receptor; Uncoupling protein; Weight gain

Indexed keywords

ADULT; CARRIER PROTEINS; COHORT STUDIES; DIET; EXERCISE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LIFE STYLE; MALE; NETHERLANDS; OBESITY; POLYMORPHISM, GENETIC; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, CELL SURFACE; SOCIAL CLASS; WEIGHT GAIN;

ADRENERGIC RECEPTOR; LEPTIN RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; UNCOUPLING PROTEIN;

ADULT; ARTICLE; DIETARY INTAKE; DNA POLYMORPHISM; FEMALE; GENETIC SUSCEPTIBILITY; HEREDITY; HUMAN; MALE; NETHERLANDS; OBESITY; PHYSICAL ACTIVITY; PRIORITY JOURNAL; WEIGHT GAIN;

EID: 85047697137     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0801964     Document Type: Article

References (54)

1. Environmental contributions to the obesity epidemic
2. Familial predisposition for obesity may modify the predictive value of serum leptin concentrations for long-term weight change in obese women
3. The body-mass index of twins who have been reared apart
4. The response to long-term overfeeding in identical twins
5. The search for human obesity genes
6. Genetics of body-weight regulation
7. The human obesity gene map: The 1999 update
8. Human uncoupling proteins and obesity
9. Relation between leptin and the regulation of glucose metabolism
10. Leptin and its potential role in human obesity
11. PPARgamma, the ultimate thrifty gene
12. Adrenoceptor genes in human obesity
13. Cardiovascular disease risk factors in The Netherlands
14. Consistency and change of body mass index and weight. A study on 5967 adult Finnish twin pairs
15. Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima Indians
16. The Bcl I polymorphism of the human uncoupling protein (ucp) gene is due to a point mutation in the 5-flanking region
17. Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPARgamma) gene in diabetic Caucasians: Identification of a Pro12Ala PPAR gamma 2 missense mutation
18. Exonic and intronic sequence variation in the human leptin receptor gene (LEPR)
19. Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function
20. Amino acid variants in the human leptin receptor: Lack of association to juvenile onset obesity
21. Baised tests of association: Comparisons of allele frequencies when departing from Hardy-Weinberg proportions
22. Metabolic predictors of weight gain
23. Self-reported weight and height
24. Impact of polymorphisms of the human beta2-adrenoceptor gene on obesity in a French population
25. Association of polymorphism in the beta2-arenergic receptor gene with obesity, hypertriglyceridaemia, and diabetes mellitus
26. The different effects of a Gln27Glu beta(2)-adrenoceptor gene polymorphism on obesity in males and in females
27. The Gln27Glu beta2-adrenergic receptor variant is associated with obesity due to subcutaneous fat accumulation in Japanese men
28. An uncoupling protein 2 gene variant is associated with a raised body mass index but not type II diabetes
29. Impact of the v/v 55 polymorphism of the uncoupling protein 2 gene on 24-h energy expenditure and substrate oxidation
30. Additive effect of A→G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity
31. Polymorphisms of uncoupling protein (UCP) and beta 3 adrenoreceptor genes in obese people submitted to a low calorie diet
32. DNA polymorphism in the uncoupling protein (UCP) gene and human body fat
33. Structure and sequence variation at the human leptin receptor gene in lean and obese Pima Indians
34. Hypertension in obesity and the leptin receptor gene locus
35. Leptin receptor gene variation and obesity: Lack of association in a white British male population
36. A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
37. Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor gamma 2 gene with obesity in two Caucasian populations
38. Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): Divergent modulating effects on body mass index in obese and lean Caucasian men
39. The Pro12Ala variant of peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) is associated with measures of obesity in Mexican Americans
40. A genetic polymorphism of the peroxisome proliferator-activated receptor gamma gene influences plasma leptin levels in obese humans
41. The Gln27Glu polymorphism in the beta2-adrenergic receptor gene is not associated with morbid obesity in Austrian women
42. Lack of association between a human beta-2 adrenoceptor gene polymorphism (gln27glu) and morbid obesity
43. Mutational analysis of the coding region of the uncoupling protein 2 gene in obese NIDDM patients: Impact of a common amino acid polymorphism on juvenile and maturity onset forms of obesity and insulin resistance
44. Molecular screening of uncoupling protein 2 gene in patients with noninsulin-dependent diabetes mellitus or obesity
45. An untranslated insertion variant in the uncoupling protein 2 gene is not related to body mass index and changes in body weight during a 26-year follow-up in Danish Caucasian men
46. Studies of genetic variability of the uncoupling protein 1 gene in Caucasian subjects with juvenile-onset obesity
47. DNA polymorphism in the uncoupling protein 1 (UCP1) gene has no effect on obesity related phenotypes in the Swedish Obese Subjects cohorts
48. Human leptin receptor gene in obese Japanese subjects: Evidence against either obesity-causing mutations or association of sequence variants with obesity
49. Combination of polymorphisms in OB-R and the OB gene associated with insulin resistance in Nauruan males
50. The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes
51. Two polymorphisms in the peroxisome proliferator-activated receptor-gamma gene are associated with severe overweight among obese women
52. Implications of genetic variability of human beta 2-adrenergic receptor structure