Amino acid variants in the human leptin receptor: Lack of association to juvenile onset obesity

Biochemical and Biophysical Research Communications

Volumn 233, Issue 1, 1997, Pages 248-252

  Echwald, Søren M ^a   Sørensen, Tina D ^a   Sørensen, Thorkild I A ^b   Tybjærg Hansen, Anne ^b,c   Andersen, Teis ^b   Chung, Wendy K ^d   Leibel, Rudolph L ^d   Pedersen, Oluf ^a  

^a STENO DIABETES CENTER   (Denmark)

^b Rigshospitalet   (Denmark)

^c GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BRAIN RECEPTOR; DNA; LEPTIN;

ARTICLE; BODY MASS; CONTROLLED STUDY; GENE FREQUENCY; GENETIC VARIABILITY; HETEROZYGOTE; HUMAN; HUMAN CELL; HYPOTHALAMUS; MAJOR CLINICAL STUDY; MALE; OBESITY; ONSET AGE; PRIORITY JOURNAL; PROTEIN VARIANT; RECEPTOR GENE; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 17344387584     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1997.6430     Document Type: Article

References (21)

1. 1. Herskind, A. M., McGue, M., Sørensen, T. I. A., and Harvald, B. (1996) Int. J. Obesity Rel. Metab. Disorders 20, 106-113.
2. 2. Stunkard, A. J., Harris, J. R., Pedersen, N. L., and McClearn, G. E. (1990) N. Engl. J. Med. 322, 1483-1487.
3. 3. Stunkard, A. J., Sørensen, T. I. A., Hanis, C., Teasdale, T. W., Chakraborty, R., Schull, W. J., and Schulsinger, F. (1986) N. Engl. J. Med. 314, 193-198.
4. 4. Sørensen, T. I. A., Price, R. A., Stunkard, A. J., and Schulsinger, F. (1989) Br. Med. J. 298, 87-90.
5. 5. Vogler, G. P., Sørensen, T. I. A., Stunkard, A. J., Srinivasan, M. R., and Rao, D. C. (1995) Int. J. Obesity Rel. Metab Disorders 19, 40-45.
6. 6. Leibel, R. L., Rosenbaum, M., and Hirsch, J. (1995) N. Engl. J. Med. 332, 621-628.
7. 7. Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M. (1994) Nature 372, 425-432.
8. 8. Tartaglia, L. A., Dembski, M., Weng, X., Deng, N. H., Culpepper, J., Devos, R., Richards, G. J., Campfield, L. A., Clark, F. T., Deeds, J., Muir, C., Sanker, S., Moriarty, A., Moore, K. J., Smutko, J. S., Mays, G. G., Woolf, E. A., Monroe, C. A., and Tepper, R. I. (1995) Cell 83, 1263-1271.
9. 9. Sørensen, T. I. A., Echwald, S. M., and Holm, J. C. (1996) Br. Med. J. 313, 953-954.
10. 10. Lee, G. H., Proenca, R., Montez, J. M., Carroll, K. M., Darvishzadeh, J. G., Lee, J. I., and Friedman, J. M. (1996) Nature 379, 632-635.
11. 11. Cioffi, J. A., Shafer, A. W., Zupancic, T. J., Smithgbur, J., Mikhail, A., Platika, D., and Snodgrass, H. R. (1996) Nature Med. 2, 585-589.
12. 12. Chen, H., Charlat, O., Tartaglia, L. A., Woolf, E. A., Weng, X., Ellis, S. J., Lakey, N. D., Culpepper, J., Moore, K. J., Breitbart, R. E., Duyk, G. M., Tepper, R. I., and Morgenstern, J. P. (1996) Cell 84, 491-495.
13. 13. Echwald, S. M., Rasmussen, S. B., Sørensen, T. I. A., Andersen, T., Tybjærg-Hansen, A., Clausen, J. O., Hansen, L., Hansen, T., and Pedersen, O. (1997) Int. J. Obesity Rel. Metab. Disorders, in press.
14. 14. Sørensen, T. I. A., and Sonne-Holm, S. (1988) Am. J. Epidemiol. 127, 104-113.
15. 15. Sonne-Holm, S., Sørensen, T. I. A., Jensen, G., and Schnohr, P. (1989) Int. J. Obesity Rel. Metab. Disorders 14, 319-326.
16. 16. Miller, S. A., Dykes, D. D., and Polesky, H. F. (1988) Nucleic Acids Res. 16, 1215-1216.
17. 17. Chung, W. K., Power-Kehoe, L., Chua, M., Chu, F., Devoto, M., Aronne, L., Huma, Z., Sothern, M., Udall, J. N., Kahle, B., Chagnon, Y., Pérusse, L., Bouchard, C., and Leibel, R. (1997)Diabetes, in press.
18. 18. Echwald, S. M., Bjorbaek, C., Hansen, T., Clausen, J. O., Vestergaard, H., Zierath, J. R., Printz, R. L., Granner, D. K., and Pedersen, O. (1995) Diabetes 44, 347-353.
19. 19. Mercer, J. G., Hoggard, N., Williams, L. M., Lawrence, C. B., Hannah, L. T., and Trayhurn, P. (1996) FEBS Lett. 387, 113-116.
20. 20. Devos, R., Richards, J. G., Campfield, L. A., Tartaglia, L. A., Guisez, Y., Vanderheyden, J., Travernier, J., Plaetinck, G., and Burn, P. (1996) Proc. Natl. Acad. Sci. USA 93, 5668-5673.
21. 21. Considine, R. V., Considine, E. L., Williams, C. J., Hyde, T. M., and Caro, J. F. (1996) Diabetes 45, 992-994.