Effect of inhaled interleukin-5 on airway hyperreactivity and eosinophilia in asthmatics

American Journal of Respiratory and Critical Care Medicine

Volumn 157, Issue 1, 1998, Pages 204-209

  Shi, Huan Zhong ^a   Xiao, Chang Qing ^a   Zhong, Ding ^a   Qin, Shou Ming ^a   Liu, Yi ^a   Liang, Guo Rong ^a   Xu, Hui ^a   Chen, Yi Qiang ^a   Long, Xue Ming ^a   Xie, Zheng Fu ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EOSINOPHIL CATIONIC PROTEIN; ESCHERICHIA COLI ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; METHACHOLINE CHLORIDE; RECOMBINANT INTERLEUKIN 5;

ADULT; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; EOSINOPHILIA; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; INHALATIONAL DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; SPIROMETRY; SPUTUM ANALYSIS;

EID: 15144358845     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.157.1.9703027     Document Type: Article

References (35)

1. Oddera, S., M. Silvestri, A. Balbo, B. O. Jovovich, R. Penna, E. Crimi, and G. A. Rossi. 1996. Airway eosinophilic inflammation, epithelial damage, and bronchial hyperresponsiveness in patients with mild-moderate, stable asthma. Allergy 51:100-107.
2. Sanderson, C. J. 1992. Interleukin-5, eosinophils, and disease. Blood 79: 3101-3109.
3. Clutterbuck, E. T., E. M. A. Hirst, and C. J. Sanderson. 1989. Human interleukin 5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6, and GM-CSF. Blood 73:1504-1512.
4. Yamaguchi, Y., I. Suda, M. Eguchi, Y. Miura, N. Harada, A. Tominaga, and K. Takatsu. 1988. Purified interleukin 5 supports the terminal differentiation and proliferation of mature eosinophilic precursors. J. Exp. Med. 167:43-56.
5. Yamaguchi, Y., Y. Hayashi, Y. Sugama, Y. Miura, T. Kasahara, S. Kitamura, M. Torisu, S. Mita, A. Tominaga, K. Takatsu, and T. Suda. 1988. Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. J. Exp. Med. 167:1737-1742.
6. Lopez, A. F., C. J. Sanderson, J. R. Gamble, H. D. Campbell, I. G. Young, and M. A. Vadas. 1988. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J. Exp. Med. 167: 219-224.
7. Fujisawa, T., R. Abu-Ghazaleh, H. Kita, C. J. Sanderson, and G. J. Gleich. 1990. Regulatory effect of cytokines on eosinophil degranulation. J. Immunol. 144:642-646.
8. Walsh, G. M., A. Hartnell, A. J. Wardlaw, K. Kurihara, C. J. Sanderson, and A. B. Kay. 1990. IL-5 enhances the in vivo adhesion of human eosinophils, but not neutrophils, in a leukocytes integrin (CD11/18)-dependent manner. Immunology 71:258-265.
9. Shi, K-Z., S.-M. Qin, G.-W. Huang, Y.-Q. Chen, C-Q. Xiao, G.-R. Liang, Z.-F. Xie, X.-Z. Qin, J. Wu, G.-X. Li, and C.-M. Zhang. 1997. Infiltration of eosinophils into the asthmatic airways caused by interleukin-5. Am. J. Respir. Cell Mol. Biol. 16:220-224.
10. American Thoracic Society. 1987. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am. Rev. Respir. Dis. 136:225-244.
11. Hargreave, F. E., G. Ryan, N. C. Thomson, P. M. O'Byrne, K. Latimer, E. F. Juniper, and J. Dolovich. 1981. Bronchial rcsponsiveness to histamine or methacholine in asthma: measurement and clinical significance. J. Allergy Clin. Immunol. 68:347-355.
12. Pin, L. A. P. Freitag, P. M. O'Byrne, A. Girgis-Gabardo, R. M. Watson, J. Dolovich, J. Denburg, and F. E. Hargreave. 1992. Changes in cellular profile of induced sputum after allergen-induced asthmatic response. Am. Rev. Respir. Dis. 145:1265-1269.
13. + T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea. Am. Rev. Respir. Dis. 146:374-377.
14. Akutsu, I., T. Kojima, A. Kariyone, T. Fukuda, S. Makino, and K. Takatsu. 1995. Antibody against interleukin-5 prevents antigen-induced eosinophil infiltration and bronchial hyperreactivity in the guinea pig airways. Immunol. Lett. 45:109-116.
15. van Oosterhout, A. J. M., A. R. C. Ladenius, H. F. J. Savelkoul, I. van Ark, K. C. Deleman, and F. P. Nikamp. 1993. Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs. Am. Rev. Respir. Dis. 147:548-552.
16. Pin, I., P. G. Gilbson, R. Kolendowicz, A. Girgis-Gabardo, J. A. Denburg, F. E. Hargreave, and J. Dolovich. 1992. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 47: 25-29.
17. Fahy, J. V., J. Liu, H. Wong, and H. A. Boushey. 1994. Analysis of cellular and biochemical constituents in induced sputum after allergen challenge: a method for studying allergic airway inflammation. J. Allergy Clin. Immunol. 93:1031-1039.
18. Fahy, J. V., J. Liu, H. Wong, and H. A. Boushey. 1993. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am. Rev. Respir. Dis. 147:1126-1131.
19. Bacci, E., S. Cianchetti, P. L. Paggiaro, S. Carnrvall, L. Bancalari, F. L. Dente, A. D. Franco, D. Giannini, B. Vagaggini, and C. Giuntini. 1996. Comparison between hypersonic and isotonic saline-induced sputum in the evaluation of airway inflammation in subjects with moderate asthma. Clin. Exp. Allergy 26:1395-1400.
20. + T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am. J. Respir. Cell Mol. Biol. 10:587-593.
21. Mauser, P. J., A. M. Pitman, X. Fernandez, S. K. Foran, G. K. Adams, III. W. Kreuter, R. W. Egan, and R. W. Chapman. 1995. Effect of an antibody to interleukin-5 in a monkey model of asthma. Am. J. Respir. Crit. Care Med. 152:467-472.
22. Robinson, D., Q. Hamid, S. Ying, A. Bentley, B. Assoufi, S. Durham, and A. B. Kay. 1993. Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-cytokine gene expression. Am. Rev. Respir. Dis. 148:401-406.
23. Ackerman, V., M. Marini, E. Vittori, A. Bellini, G. Vassali, and S. Mattoli. 1994. Detection of cytokines and their cell sources in bronchial biopsy specimens from asthmatic patients: relationship to atopic status, symptoms, and level of airway hyperresponsiveness. Chest 105:687-696.
24. Hamid, Q., M. Azzawi, Y. Sun, R. Moqbel, A. J. Wardlaw. C. J. Corrigan, B. Bradley, S. R. Durham, J. V. Collins, P. K. Jeffery, D. J. Quint, and A. B. Kay. 1991. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J. Clin. Invest. 87:1541-1546.
25. Pizzichini, E., M. M. M. Pizzichini, A. Efthimiadis, S. Evans, M. M. Morris, D. Squillace, G. J. Gleich, J. Dolovich, and F. E. Hargeave. 1996. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am. J. Respir. Crit. Care Med. 154:308-317.
26. Gleich, G. J. 1990. The eosinophil and bronchial asthma: current understanding. J. Allergy Clin. Immunol. 85:422-436.
27. Wardlaw, A. J., S. Dunnette, G. J. Gleich, J. V. Collins, and A. B. Kay. 1988. Eosinophils and mast cells in bronchoalveolar lavage in subjects with asthma: relationship to bronchial hyperreactivity. Am. Rev. Respir. Dis. 137:62-69.
28. Gundel, R. H., L. G. Letts, and G. J. Gleich. 1941. Human eosinophil major basic protein induces airway constriction and airway hyperresponsiveness in primates. J. Clin. Invest. 87:1470-1473.
29. Lefort, J., M. A. Nahori, C. Ruffie, B. B. Vargaftig, and M. Pretolani. 1996. In vivo neutralization of eosinophil-derived major basic protein inhibits antigen-induced bronchial hyperreactivity in sensitized guinea pigs. J. Clin. Invest. 97:1117-1121.
30. Busse, W. W., W. F. Calhoun, and J. D. Sedgwick. 1993. Mechanism of airway inflammation in asthma. Am. Rev. Respir. Dis. 147:S20-S24.
31. Rylander, R., B. Bake, J. J. Fisher, and I. M. Helander. 1989. Pulmonary function and symptoms after inhalation of endotoxin. Am. Rev. Respir. Dis. 140:981-986.
32. Michel, O., J. Duchateau, and R. Sergysels. 1989. Effects of inhaled endotoxin on bronchial reactivity in asthmatic and normal subjects. J. Appl. Physiol. 66:1059-1064.
33. Michel, O., R. Ginanni, and R. Sergysels. 1992. Relation between the bronchial obstructive response to inhaled lipopolysaccharide and bronchial responsiveness to histamine. Thorax 47:288-291.
34. Hunt, L. W., G. J. Gleich, T. Ohnishi, D. A. Weller, E. S. Mansfield, H. Kita, and S. Sur. 1994. Endotoxin contamination causes neutrophilia following pulmonary allergen challenge. Am. J. Respir. Crit. Care Med. 149:1471-1475.
35. Michel, O., R. Ginanni, B. Le Bon, J. Content, J. Duchateau, and R. Sergysels. 1992. Inflammatory response to acute inhalation of endotoxin in asthmatic patients. Am. Rev. Respir. Dis. 146:352-357.